RAMEDA

Company Information

History :

Our Vision:To become the most valuable emerging pharmaceutical company in Egypt.Our Mission:To provide our customers quality health care solutions in a cost effective manner by developing products and services that satisfy their health requirements.EstablishmentRameda began operations in 1994 and was established by a group of Gulf investors with the intention of creating one of the largest pharmaceutical operations in the region.Owners hired V-Konsult of Germany to create a state-of-the art design.Contracted British Carter Construction company to build the Rameda’s facilities.Partnership with AlconIn 1999, Rameda entered into an agreement with Alcon to manufacture – under license - their ophthalmology products. In order to guarantee the quality of their products, Alcon built one of the highest quality eye production facilities in the region at Rameda.Quality enhancementRameda renewed the syrup production to become GMP (Good Manufacturing Practice).A new Beginning In 2011, Compass Capital led a consortium of private equity investors for the acquisition of 100% of Rameda. Compass Capital plans to establish Rameda as a regional leader in the industry.To execute this strategy Rameda hired a new management team with a proven track record to complement the existing team.Company has commissioned M+W Group to transform solid dosage and beta lactam areas into GMP. Brining entire facility to compliance.

 

Logo

  • Size of Organization :: 10,001+ employees

  • Type OF Organization: pharmaceutical

  • Range of expected salary .: After interview

  • Car policy: yes

  • Incentive scheme: yes

  • Factory: yes

  • Company rank (IMS) year 2018: 75

  • Company link: http://www.ramedapharma.com/

Products

Trade NameGeneric NameCompanyPharmacology PriceDescription
ACETASEE 1% eye dropsPREDNISOLONERAMEDA7.5About Prednisolone*Systemic synthetic Glucocorticoid, Immunosuppressant.*Mechanism of Action of Prednisolone*The drug exerts it`s pharmacological action by penetrating and binding to cytoplasmic receptor protein and causes a structural change in steroid receptor complex. This structural change allows it`s migration in to the nucleus and then binding to specific sites on the DNA which leads to transcription of specific m-RNA and which ultimately regulates protein synthesis. It exerts more selective glucocorticoid action with little mineralocorticoid actions. *The drug exerts anti-inflammatory and immunosuppressant actions as follows: - 1) Induce lipocortins in macrophages, endothelium, and fibroblasts which inhibits phospholipase A2 and thus decreases the production of Prostaglandins, leukotriens (LT), and platelet activating factor, 2) Causes negative regulation of genes for cytokines in macrophages, endothelial cells and lymphocytes and thus decreases the production of interleukin
ADAMINE 100mg 20 Caps.AMANTADINERAMEDAAnti-Viral.Uncoating inhibitor7(Indications) :* This medication is a synthetic anti-viral and antiparkinson agent, prescribed for Parkinson s disease and also for treating certain types of flu. It also is used to prevent and treat respiratory infections caused by influenza A virus** (Dosage) :*- Influenza A -100 mg/day for 5 days. *- Herpes zoster- 100 mg twice daily for 14 days, may continue for another 14 day if pain persists.*Parkinson s disease-100 mg/day, up to 100 mg twice daily after 1 wk. Max: 400 mg/day**
AGGREX 250mg 20 tab.ACETYLSALICYLIC ACIDRAMEDANSAID.Salicylates6Description:*belongs to a group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs)**Indication:*Mild to moderate pain including headache, migraine, nerve pain (neuralgia), toothache, sore throat, period pain.*Relieving aches, pains and fever associated with colds and flu.*Relieving pain and inflammation of sprains and strains, rheumatic pain, sciatica, backache, fibrositis, muscular aches and pains, joint swelling, and stiffness.*To improve survival in emergency situation of a heart attack.**Warning!*Children under 16 years of age should not take aspirin, unless on the advice of a doctor. This is because aspirin use in children has been associated with a rare condition called Reye s syndrome.This condition affects the brain and liver and though extremely rare, can be fatal. ********
AGGREX 75mg 60 tabletsACETYLSALICYLIC ACIDRAMEDANSAID.Salicylates12Description:*belongs to a group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs)**Indication:*Prophylaxis of cerebrovascular disease or myocardial infarction*To improve survival in emergency situation of a heart attack.
AMOFLUXIN 1 GM 12 F.C. TABS.AMOXICILLIN -- FLUCLOXACILLINRAMEDAPenicillins.Penicillin with B-lactamase inhbitor14.4"amoxycillin and flucloxacillin - generally exhibit an additive effect against sensitive bacteria and bacteria that are sensitive to amoxycillin or to flucloxacillin remain sensitive to the combination, showing that antagonism does not occur when the two components are combined.*Typical indications include:*Acute and chronic bronchitis *Pelvic inflammatory disease*Pneumonia *Urinary tract infections*Ear, nose and throat infections Skin and soft tissue infections*Gynaecological infections"
AMOFLUXIN 500mg 12 Caps.AMOXICILLIN -- FLUCLOXACILLINRAMEDAPenicillins.Penicillin with B-lactamase inhbitor10.5"amoxycillin and flucloxacillin - generally exhibit an additive effect against sensitive bacteria and bacteria that are sensitive to amoxycillin or to flucloxacillin remain sensitive to the combination, showing that antagonism does not occur when the two components are combined.*Typical indications include:*Acute and chronic bronchitis *Pelvic inflammatory disease*Pneumonia *Urinary tract infections*Ear, nose and throat infections Skin and soft tissue infections*Gynaecological infections"
AMOFLUXIN 500mg vialAMOXICILLIN -- FLUCLOXACILLINRAMEDAPenicillins.Penicillin with B-lactamase inhbitor5.5"amoxycillin and flucloxacillin - generally exhibit an additive effect against sensitive bacteria and bacteria that are sensitive to amoxycillin or to flucloxacillin remain sensitive to the combination, showing that antagonism does not occur when the two components are combined.*Typical indications include:*Acute and chronic bronchitis *Pelvic inflammatory disease*Pneumonia *Urinary tract infections*Ear, nose and throat infections Skin and soft tissue infections*Gynaecological infections"
ANAUSAN 120ml syrupMETOCLOPRAMIDE -- VITAMIN B6RAMEDA4.8About Metoclopramide*It is a dopamine antagonist - antiemetic gastroprokinetic agent.*Mechanism of Action of Metoclopramide*Metoclopramide acts through both serotonergic and dopaminergic receptors. Metoclopramide binds to Serotonin (5 HT3 &5HT4) and Dopamine (D2) receptor. *Antiemetic action: Metoclopramide inhibits Dopamine receptor in the chemoreceptor trigger zone and produces antiemetic action. *Intestinal motility modifying action: The binding of Metoclopramide on 5HT4 receptor will activate interneuron and enhance the release of acetylcholine innervating the smooth muscles. This produces gastric emptying and enhances lower esophageal sphincter tone. *Migraine: Metoclopramide is used in migraine to relieve nausea and vomiting *Anaesthetic adjuncts: It is used preoperatively in order to reduce the post operative vomiting.
BEMASTRIM 10 mg 7 F.C. Tab.ROSUVASTATINRAMEDAAntihyperlipidemic.Statins31.2About Rosuvastatin*Statin, HMG-CoA Reductase Inhibitor, Antilipemic.*Mechanism of Action of Rosuvastatin*It is a hypolipidaemic statin which competitively inhibits the conversion of 3-hydroxy-3-methyl glutaryl coenzyme A (HMG CoA) to mevalonate. The drug exerts it`s action by specific inhibition of enzyme- 3-hydroxy-3-methyl glutaryl coenzyme A reductase (HMG CoA reductase) and reduces cholesterol synthesis up to 50% at therapeutic doses. This results in compensatory increase in low density lipoprotein (LDL) receptor expression in liver which ultimately leads to increased receptor mediated uptake and catabolism of intermediate density lipoprotein(IDL) and low density lipoprotein (LDL). It causes dose dependent lowering of LDL cholesterol and reduces hepatic synthesis of very low density lipoprotein (VLDL) and lowers plasma triglyceride levels. It also increases high density lipoprotein (HDL) levels.
CEPHRAMEDIN 250 MG vialCEPHRADINERAMEDA5.25"Description *A semi-synthetic cephalosporin antibiotic.**Mechanism of action Cefradine* is a first generation cephalosporin antibiotic with a spectrum of activity similar to Cefalexin. Cefradine, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins- it is possible that Cefradine interferes with an autolysin inhibitor."
CEPHRAMEDIN 500 MG vialCEPHRADINERAMEDA6.25"Description *A semi-synthetic cephalosporin antibiotic.**Mechanism of action Cefradine* is a first generation cephalosporin antibiotic with a spectrum of activity similar to Cefalexin. Cefradine, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins- it is possible that Cefradine interferes with an autolysin inhibitor."
CLINDACINE 1% topical gel 20 GMCLINDAMYCINRAMEDAAntibiotic.Lincomycins7mechanism*Clindamycin works by preventing bacteria from producing proteins that are essential to them. Without these proteins the bacteria cannot grow, replicate and increase in numbers. The remaining bacteria eventually die or are destroyed by the immune system. This treats the infection.**indication:*Bacterial infections of the skin and soft tissue, such as infected ulcers, erysipelas, cellulitis.*Bacterial infections of joints and bone (eg osteomyelitis).*Bacterial infections of the abdominal cavity (peritonitis).*Dental abscesses.*Treating falciparum malaria (unlicensed use).****
CLINDACINE 150mg 6 Caps.CLINDAMYCINRAMEDAAntibiotic.Lincomycins10.5mechanism*Clindamycin works by preventing bacteria from producing proteins that are essential to them. Without these proteins the bacteria cannot grow, replicate and increase in numbers. The remaining bacteria eventually die or are destroyed by the immune system. This treats the infection.**indication:*Bacterial infections of the skin and soft tissue, such as infected ulcers, erysipelas, cellulitis.*Bacterial infections of joints and bone (eg osteomyelitis).*Bacterial infections of the abdominal cavity (peritonitis).*Dental abscesses.*Treating falciparum malaria (unlicensed use).****
CLINDACINE 300 mg 12 Caps.CLINDAMYCINRAMEDAAntibiotic.Lincomycins12mechanism*Clindamycin works by preventing bacteria from producing proteins that are essential to them. Without these proteins the bacteria cannot grow, replicate and increase in numbers. The remaining bacteria eventually die or are destroyed by the immune system. This treats the infection.**indication:*Bacterial infections of the skin and soft tissue, such as infected ulcers, erysipelas, cellulitis.*Bacterial infections of joints and bone (eg osteomyelitis).*Bacterial infections of the abdominal cavity (peritonitis).*Dental abscesses.*Treating falciparum malaria (unlicensed use).****
CLOROCEF 250mg/5ml susp. 60 MLCEFACLORRAMEDAAntibiotic.cephalosporin.Second-generation27About Cefaclor*A second-generation cephalosporin antibiotic, Oral Broad-spectrum antibiotics.**Mechanism of Action*Cefaclor is a 2nd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefaclor inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefaclor. *Cefaclor has more activity against ampicillin resistant haemophilus influenzae and branhamella catarrhalis **Indications for Cefaclor*1.Pneumonia & Pulmonary infections *2.Otitismedia *3.Urinary tract infections & genital tract infections *4.Pharyngitis & Tonsillitis *5.Skin & wound infections *6.Bronchitis & Sinusitis
COLONA 30 F.C.tab.MEBEVERINE -- SULPIRIDERAMEDA31.5About Mebeverine*Reserpine derivative, antimuscarinic, a musculotropic antispasmodic, Motility stimulant.*Mechanism of Action of Mebeverine*Mebeverine has a direct relaxant effect on smooth muscle. This will inhibits gastrointestinal propulsive motility and gastric acid secretion.
DEFLAX sachetsSIMETHICONE -- SORBITOLRAMEDA2.5About Simethicone*Oral anti-foaming agent, Silicones, Antiflatulent.*Mechanism of Action of Simethicone*This anti-gas (anti-flatulence) medication acts in the stomach and intestines to change the surface tension of gas bubbles, enabling smaller bubbles to join together into bigger bubbles. It results elimination of gas more easily by belching or passing flatus.*Indications for Simethicone*1. Abdominal pain which is due to excessive gas in the digestive tract *2. Before gastroscopy or radiography of the bowel *Typical Dosage for Simethicone*Oral- *Adults and teenagers- *60 -125mg four times a day, after meals and at bedtime. Not more than 500 mg should be taken in twenty-four hours. *Chewable tablets: *Adults and teenagers- *40 -125 mg four times a day, after meals and at bedtime or 150 mg three times a day, after meals. Not more than 500 mg should be taken in twenty-four hours. *Suspension: *Adults and teenagers- *40 -95 mg four times a day, after meals and at bedtime.
DIANORMAL 80mg 20 tab.GLICLAZIDERAMEDAAnti-Diabetic.Secretagogues.Sulfonylurea8.5"About Gliclazide*First generation Sulfonylurea, Oral Antidiabetic Agent.*Mechanism of Action of Gliclazide*It is an antidiabetic drug which exerts it`s action by increasing insulin release from the pancreas and by improving glucose tolerance. It acts on the ""sulfonylurea receptors"" on pancreatic ?-cell membrane and reduces conductance of ATP sensitive K -- channels and thus causes depolarization. This enhances Ca2 -- influx and degranultion and thus increases insulin secretion rate at any glucose concentration. It primarily increases 2nd phase insulin secretion and has little effect on 1st phase. It also slows hepatic degradation of insulin and minor action of reducing glucagon release and increasing Somatostatin release. It also exerts extrapancreatic action- by sensitizing the target tissues such as liver to insulin action. It increases the number of insulin receptors and through a post receptor action improving translation of receptor activation. It also possesses anti-platelet actio"
DOLOBAN 250mg tabDIFLUNISALRAMEDANSAID.Antirehumatic.Salicylates6.5About Diflunisal*NSAID,salicylic acid derivative, Nonopioid analgesic, anti-inflammatory.
FEMIREEM 30 F.C. TABS.GENISTEIN -- VITAMIN D3RAMEDA27Used during menopause.*Dose: Once daily.*
FEMIREEM PLUS 30 H.G. CAPS.GENISTEIN -- CALCIUM -- VITAMIN D3 -- VITAMIN KRAMEDA33Used during menopause.*Dose: Once daily.*
FINCAR 5mg 10f.c.tab.FINASTERIDERAMEDA22About Finasteride*5 Alpha-Reductase Inhibitor, Synthetic anti-androgen.**Mechanism of Action of Finasteride*This synthetic 4-azasteroid derivative competitively inhibits steroid 5alpha reductase, which is an enzyme responsible for active androgen dehydrotestosterone (this enzyme influences the development of prostate gland, so decreasing level of this hormone relieve the symptoms associated with benign prostatic hyperplasia)from testosterone.**Indications for Finasteride*1. Benign prostatic hyperplasia *2. 1st stage of prostate cancer *3. Hirsuitism *4. Acne *5. Adjuvant therapy of radical prostectomy *6. Androgenic baldness
FLU-C 6 sachets.CAFFEINE -- CHLORPHENIRAMINE -- PARACETAMOL(ACETAMINOPHEN) -- VITAMIN CRAMEDA6.5
GERVIZINE 20 Caps.CALCIUM PANTOTHENATE -- FOLIC ACID -- MAGNESIUM -- MANGANESE -- NICOTINAMIDE -- VITAMIN(A -- B1 -- B2 -- B6 -- C -- D3 -- E) -- ZINCRAMEDAvitamin12"Indication Studied for the treatment of many uses such as treatment of testicular torsion, diabetic ulceration, wound healing, acne, obesity, diabetic peripheral polyneuropathy. It has also been investigated for its hypolipidemic effects and as cholesterol lowering agent.*Mechanism of action Pantothenic acid is incorporated into COENZYME A and protects cells against peroxidative damage by increasing the level of GLUTATHIONE."
HIPRESS-D 20 Caps.ATENOLOLRAMEDAAnti-hypertensive.Beta blocker.Selective B111"Description : *A cardioselective beta-adrenergic blocker possessing properties and potency similar to propranolol, but without a negative inotropic effect.**dose:*Adult: PO- Angina pectoris- HTN- 50-100 mg once daily. Migraine prophylaxis 50-100 mg/day. **Indication :*For the management of hypertention and long-term management of patients with angina pectoris**Mechanism of action:*Like metoprolol, atenolol competes with sympathomimetic neurotransmitters such as catecholamines for binding at beta(1)-adrenergic receptors in the heart and vascular smooth muscle, inhibiting sympathetic stimulation. This results in a reduction in resting heart rate, cardiac output, systolic and diastolic blood pressure, and reflex orthostatic hypotension. Higher doses of atenolol also competitively block beta(2)-adrenergic responses in the bronchial and vascular smooth muscles.*"
IDELOX 400mg 5 F.C. Tab.MOXIFLOXACINRAMEDAAntibiotic.quinolone58About Moxifloxacin*A third generation synthetic fluoroquinolone Antibiotic, A broad spectrum antibiotic.*Mechanism of Action of Moxifloxacin*Moxifloxacin acts by inhibiting the enzyme DNA gyrase (Topoisomerase 2) and Topoisomerase 4.DNA gyrase helps in the formation of a highly condensed three dimensional structure of the DNA by its nicking and closing activity and also by introducing negative supercoil in to the DNA double helix. Moxifloxacin inhibits DNA gyrase which results in abnormal linkage between opened DNA and gyrase and negative supercoiling is impaired. This will inhibits transcription of DNA in to RNA and subsequent protein synthesis.**Indications for Moxifloxacin*1.Pneumonia *2.Bronchitis *3.Sinusitis *4.Skin infections *Interactions for Moxifloxacin*Antiarrhythmic agents (amiodarone, bretylium, disopyramide, procainamide, quinidine, sotalol): The risk of threatening cardiac arrhythmias may be increased.
INDOTOPIC 1% gel 20 gmINDOMETHACINRAMEDANSAID.Acetic acid derivatives5.25About Indomethacin*NSAID, Indole derivative, Anti-inflammatory, potent antipyretic and analgesic.**Mechanism of Action of Indomethacin*Indomethacin acts by inhibition of Prostaglandin (PGs) synthesis and their release at the site of injury. Prostaglandins cause tenderness and amplify the action of other algesics. Indomethacin does not affect the tenderness induced by PGs but block the pain producing mechanism induced by inflammatory mediators by inhibiting the enzyme cyclo-oxygenase. **Interactions for Indomethacin*Anticoagulants: May prolong prothrombin time. Instruct patients to watch for signs & symptoms of bleeding. *Beta-Blockers: Antihypertensive effect may be blunted. *Cyclosporine: Nephrotoxicity of both agents may be increased. *Digoxin: Serum digoxin levels may be increased by ibuprofen and indomethacin. *Hydantoins: Serum hydantoin levels increased resulting in increased pharmacological and toxic effects. *Lithium: Serum lithium levels may be increased. *
KIZOL 200mg 10 tab. (CANCELLED)KETOCONAZOLERAMEDAantifungals.Imidazoles21.6About Ketoconazole*Imidazole derivative, A broad spectrum Antifungal.**Mechanism of Action of Ketoconazole*Ketoconazole is fungicidal or fungistatic depending on concentrations. I t inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochromeP450 enzyme 14 alpha demethylase and impair ergosterol synthesis. This will alter cell membrane and its permeability. This will results in loss of intracellular components. It also inhibits biosynthesis of triglycerides and phospholipids by fungi. It also inhibits several enzymes (e.g. Oxidative and peroxidative enzymes) which are involved in detoxification process. This will leads to cellular necrosis. **Interactions for Ketoconazole*Antacids & Histamine H2 antagonists: Increased gastric pH may inhibit ketoconazole absorption. *Isoniazid: The bioavailability of Ketoconazole may be decreased. *Rifampicin: Decreased serum levels of either drug may occur. **
LACTULAX 67% 120ml syrupLACTULOSERAMEDALaxative12About Lactulose*A synthetic Disaccharide, Osmotic Laxative, Ammonium Detoxicant.*Mechanism of Action of Lactulose*Laxative: Lactulose is a synthetic disaccharide of galactose and fructose that resist intestinal disaccharidase activity. The sugars are joined by a beta glycosidic linkage and are resistant to hydrolysis by human digestive enzymes. Lactulose is fermented by a limited number of colonic bacteria. This can lead to changes in the colonic ecosystem in favor of some bacteria, such as lactobacilli and bifidobacteria, which may confer some health benefits. The products of fermentation include lactic acid and small-chain fatty acids. Degradation to short chain fatty acids also increases the osmotic pressure in the intestinal lumen. It also cause an increase in fecal volume due to intraluminal water retention and stimulate colonic propulsive motility result in increased fecal bulk and stimulation of peristalsis. *
LINTARAM 90MG 30 -- 20 FILM COATED TABLETTICAGRELORRAMEDA203.25Ticagrelor is a platelet aggregation inhibitor. It works by slowing or stopping platelets from sticking to blood vessel walls or injured tissues.**Ticagrelor is used for reducing the risk of stroke, heart attack, or death in certain patients who have had a heart attack or who have angina (chest pain). It should be used along with aspirin as directed by your doctor.
MAGNETREL 10/20MG 30 Caps.AMLODIPINE -- BENAZEPRILRAMEDAAnti-hypertensive.Combined ACE with calcium channel blocker79"Mechanism of Action of Amlodipine*Amlodipine is a second generation dihydropyridine Ca channel blocker. It exerts it`s antihypertensive, antianginal actions through blocking the influx of Ca ions through voltage gated L-type Ca channels to the peripheral vascular smooth muscle cells, Coronary smooth muscle cells and to the myocardial cells. Thus causes dilatation of vascular endothelium, decrease peripheral resistance, & reduce myocardial oxygen demand .It markedly relax arterioles and milder effects on veins. They do not compromise haemodynamics and cerebral and renal perfusion.*Mechanism of action Benazeprilat, the active metabolite of Benazepril, competes with angiotensin I for binding at the angiotensin-converting enzyme, blocking the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in decreased plasma angiotensin II. As angiotensin II is a vasoconstrictor and a negative-feedback mediator for renin activity, lower concentrations result in a decrease in blo"
MAGNETREL 2.5/10MG 30 Caps.AMLODIPINE -- BENAZEPRILRAMEDAAnti-hypertensive.Combined ACE with calcium channel blocker54"Mechanism of Action of Amlodipine*Amlodipine is a second generation dihydropyridine Ca channel blocker. It exerts it`s antihypertensive, antianginal actions through blocking the influx of Ca ions through voltage gated L-type Ca channels to the peripheral vascular smooth muscle cells, Coronary smooth muscle cells and to the myocardial cells. Thus causes dilatation of vascular endothelium, decrease peripheral resistance, & reduce myocardial oxygen demand .It markedly relax arterioles and milder effects on veins. They do not compromise haemodynamics and cerebral and renal perfusion.*Mechanism of action Benazeprilat, the active metabolite of Benazepril, competes with angiotensin I for binding at the angiotensin-converting enzyme, blocking the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in decreased plasma angiotensin II. As angiotensin II is a vasoconstrictor and a negative-feedback mediator for renin activity, lower concentrations result in a decrease in blo"
MAGNETREL 5/10MG 30 Caps.AMLODIPINE -- BENAZEPRILRAMEDAAnti-hypertensive.Combined ACE with calcium channel blocker63"Mechanism of Action of Amlodipine*Amlodipine is a second generation dihydropyridine Ca channel blocker. It exerts it`s antihypertensive, antianginal actions through blocking the influx of Ca ions through voltage gated L-type Ca channels to the peripheral vascular smooth muscle cells, Coronary smooth muscle cells and to the myocardial cells. Thus causes dilatation of vascular endothelium, decrease peripheral resistance, & reduce myocardial oxygen demand .It markedly relax arterioles and milder effects on veins. They do not compromise haemodynamics and cerebral and renal perfusion.*Mechanism of action Benazeprilat, the active metabolite of Benazepril, competes with angiotensin I for binding at the angiotensin-converting enzyme, blocking the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in decreased plasma angiotensin II. As angiotensin II is a vasoconstrictor and a negative-feedback mediator for renin activity, lower concentrations result in a decrease in blo"
MAGNETREL 5/20MG 30 Caps.AMLODIPINE -- BENAZEPRILRAMEDAAnti-hypertensive.Combined ACE with calcium channel blocker72"Mechanism of Action of Amlodipine*Amlodipine is a second generation dihydropyridine Ca channel blocker. It exerts it`s antihypertensive, antianginal actions through blocking the influx of Ca ions through voltage gated L-type Ca channels to the peripheral vascular smooth muscle cells, Coronary smooth muscle cells and to the myocardial cells. Thus causes dilatation of vascular endothelium, decrease peripheral resistance, & reduce myocardial oxygen demand .It markedly relax arterioles and milder effects on veins. They do not compromise haemodynamics and cerebral and renal perfusion.*Mechanism of action Benazeprilat, the active metabolite of Benazepril, competes with angiotensin I for binding at the angiotensin-converting enzyme, blocking the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in decreased plasma angiotensin II. As angiotensin II is a vasoconstrictor and a negative-feedback mediator for renin activity, lower concentrations result in a decrease in blo"
MAGSILON 120ml susp.DIMETHICONE -- MAGALDRATERAMEDA6About Dimethicone*Oral anti -foaming agent, a flexible silicone polymer, Antiflatulent ,Antibloating agent.*Mechanism of Action of Dimethicone*Activated Dimethicone relieves flatulence by dispensing and preventing formation of mucus surrounding gas pockets in the gastro-intestinal tract. It lowers the surface tension of the gas bubbles and bringing together all the small bubbles of gas (coalesce) to form a large bubble, which is then expelled. Thus the gas is freed by belching or passing flatus. *Antiflatulents are added to an antacid gum coating to be effective antigas materials and eliminate trapped gas. The most common antigas material is Dimethicone and when mixed with silicone dioxide becomes Simethicone. Simethicone is also referred to as activated Dimethicone. Simethicone is the most common antigas material and may be the only drug approved antiflatulent. *As the antacid chewing tablet is chewed, the active antacid and antiflatulent in the gum coating is released into the s
MAGSILON 20 chew. tab.DIMETHICONE -- MAGALDRATERAMEDA5About Dimethicone*Oral anti -foaming agent, a flexible silicone polymer, Antiflatulent ,Antibloating agent.*Mechanism of Action of Dimethicone*Activated Dimethicone relieves flatulence by dispensing and preventing formation of mucus surrounding gas pockets in the gastro-intestinal tract. It lowers the surface tension of the gas bubbles and bringing together all the small bubbles of gas (coalesce) to form a large bubble, which is then expelled. Thus the gas is freed by belching or passing flatus. *Antiflatulents are added to an antacid gum coating to be effective antigas materials and eliminate trapped gas. The most common antigas material is Dimethicone and when mixed with silicone dioxide becomes Simethicone. Simethicone is also referred to as activated Dimethicone. Simethicone is the most common antigas material and may be the only drug approved antiflatulent. *As the antacid chewing tablet is chewed, the active antacid and antiflatulent in the gum coating is released into the s
MARVIGOLINE 0.5mg 2 tab.CABERGOLINERAMEDA45"Description *Cabergoline, an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor. It is used to treat hyperprolactinemic disorders and Parkinsonian Syndrome. Cabergoline possesses potent agonist activity on dopamine D2 receptors.**Indication *For the treatment of hyperprolactinemic disorders, either idiopathic or due to prolactinoma (prolactin-secreting adenomas). May also be used to manage symptoms of Parkinsonian Syndrome as monotherapy during initial symptomatic management or as an adjunct to levodopa therapy during advanced stages of disease.**Mechanism of action The dopamine D2 receptor is a 7-transmembrane G-protein coupled receptor associated with Gi proteins. In lactotrophs, stimulation of dopamine D2 causes inhibition of adenylyl cyclase, which decreases intracellular cAMP concentrations and blocks IP3-dependent release of Ca2 -- from intracellular stores. Decreases in intracellular calcium levels may also be brought about via inhibition of calcium"
MAXIPAN 30 F.C. Tab.DIFLUNISAL -- NAPROXENRAMEDANSAID.Analgesic.Combination32.4About Diflunisal*NSAID,salicylic acid derivative, Nonopioid analgesic, anti-inflammatory.
MAXIPRIL 20mg 30 tab.LISINOPRILRAMEDAAnti-hypertensive.ACE36About Lisinopril*Dicarboxylate-containing Angiotensin-Converting Enzyme (ACE) Inhibitor, Antihypertensive.*Mechanism of Action of Lisinopril*It is an angiotensin converting enzyme inhibitor prevents the conversion of angiotensin-1 to angiotensin-2 and abolishes the pressor actions of angiotensin. It decreases aldosterone secretion, sodium and water retention, and total peripheral resistance, leads to fall in BP. The arterioles dilate and the compliance of larger arteries is increased. Both systolic and diastolic BP is lowered. It has no effect on cardiac output and cardiovascular reflexes. There is little dilatation of capacitance vessels- so postural hypotension is not a problem. The drug does not compromise renal, cerebral, and coronary blood flow. BP lowering depending up on sodium status and renin angiotensin activity. So greater fall in BP occurs in Reno vascular accelerated and malignant hypertension.
MAXIPRIL 5mg 30 scored tab.LISINOPRILRAMEDAAnti-hypertensive.ACE18About Lisinopril*Dicarboxylate-containing Angiotensin-Converting Enzyme (ACE) Inhibitor, Antihypertensive.*Mechanism of Action of Lisinopril*It is an angiotensin converting enzyme inhibitor prevents the conversion of angiotensin-1 to angiotensin-2 and abolishes the pressor actions of angiotensin. It decreases aldosterone secretion, sodium and water retention, and total peripheral resistance, leads to fall in BP. The arterioles dilate and the compliance of larger arteries is increased. Both systolic and diastolic BP is lowered. It has no effect on cardiac output and cardiovascular reflexes. There is little dilatation of capacitance vessels- so postural hypotension is not a problem. The drug does not compromise renal, cerebral, and coronary blood flow. BP lowering depending up on sodium status and renin angiotensin activity. So greater fall in BP occurs in Reno vascular accelerated and malignant hypertension.
MEGAFEN 20 tab.IBUPROFEN -- PARACETAMOL(ACETAMINOPHEN)RAMEDA8.5Ibuprofen is a type of medicine called a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the action of a substance in the body called cyclo-oxygenase (COX). Cyclo-oxygenase is involved in the production of various chemicals in the body, some of which are known as prostaglandins. Prostaglandins are produced in response to injury and certain diseases and conditions, and cause pain, swelling and inflammation. NSAIDs block the production of these prostaglandins and are therefore effective at reducing inflammation and pain.**It is thought paracetamol reduces fever by affecting an area of the brain that regulates our body temperature (the hypothalamic heat-regulating centre).**
MEGAFEN-N 100MG/5ML SUSP. 120 MLIBUPROFENRAMEDANSAID.Propionic acid derivatives10.5Ibuprofen is a type of medicine called a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the action of a substance in the body called cyclo-oxygenase (COX). Cyclo-oxygenase is involved in the production of various chemicals in the body, some of which are known as prostaglandins. Prostaglandins are produced in response to injury and certain diseases and conditions, and cause pain, swelling and inflammation. NSAIDs block the production of these prostaglandins and are therefore effective at reducing inflammation and pain.**It is thought paracetamol reduces fever by affecting an area of the brain that regulates our body temperature (the hypothalamic heat-regulating centre).**
MEGAFEN-N 100MG/5ML SUSP. 60 MLIBUPROFENRAMEDA4.75Ibuprofen is a type of medicine called a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the action of a substance in the body called cyclo-oxygenase (COX). Cyclo-oxygenase is involved in the production of various chemicals in the body, some of which are known as prostaglandins. Prostaglandins are produced in response to injury and certain diseases and conditions, and cause pain, swelling and inflammation. NSAIDs block the production of these prostaglandins and are therefore effective at reducing inflammation and pain.**It is thought paracetamol reduces fever by affecting an area of the brain that regulates our body temperature (the hypothalamic heat-regulating centre).**
MUCLEAR 20 Caps.BROMHEXINE -- GUAIFENESINRAMEDA4.75"(Indications):*This medication is a mucolytic agent, prescribed for various respiratory diseases such as emphysema with bronchitis pneumoconiosis, chronic inflammatory pulmonary conditions, tracheobronchitis (respiratory tract inflammation), bronchiectasis, bronchitis with bronchospasm asthma. **(dosage) :* The recommended dose is 30-120 mg/day in 2-3 divided doses.**(Warnings and Precautions) : * Caution needed for pregnant and breastfeeding women."
MUCLEAR 4mg/5ml 120ml syrupBROMHEXINERAMEDA4.75About Bromhexine*Mucolytic (secretolytic)**Mechanism of Action of Bromhexine*Bromhexine hydrochloride acts as a mucokinetic and mucolytic agent. It decreases mucus viscosity by altering its structure. It depolymerises mucopolysaccharides directly as well as by liberating lysosomal enzymes and network of fibres in tenacious sputum is broken. It induces thin copious bronchial secretion.**Indications for Bromhexine*1. As Expectorant and mucolytic *2. Conditions associated with production of viscid mucous *3. Bronchitis *4. Pharyngitis *5. Laryngitis *6. Rhinitis *7. Sinusitis *8. Asthmatic bronchitis *9. Mucous bronchiectasis *10.Chronic Pneumonia.**dose*Oral: 8mg thrice daily. *Children (5 to 10 years): 4mg thrice daily *Children (1 to 5 years): 4mg twice da
MUCOSIN 15mg 20 LozengesAMBROXOLRAMEDA6.25"(Indications):*This medication is a mucolytic agent, prescribed for various respiratory diseases such as emphysema with bronchitis pneumoconiosis, chronic inflammatory pulmonary conditions, tracheobronchitis (respiratory tract inflammation), bronchiectasis, bronchitis with bronchospasm asthma. **(dosage) :* The recommended dose is 30-120 mg/day in 2-3 divided doses.**(Warnings and Precautions) : * Caution needed for pregnant and breastfeeding women.*"
MUCOSIN 7.5mg/ml oral dropsAMBROXOLRAMEDA5"(Indications):*This medication is a mucolytic agent, prescribed for various respiratory diseases such as emphysema with bronchitis pneumoconiosis, chronic inflammatory pulmonary conditions, tracheobronchitis (respiratory tract inflammation), bronchiectasis, bronchitis with bronchospasm asthma. **(dosage) :* The recommended dose is 30-120 mg/day in 2-3 divided doses.**(Warnings and Precautions) : * Caution needed for pregnant and breastfeeding women.*"
MUCOSIN PLUS 120ml syrupAMBROXOL -- GUAIFENESINRAMEDA7About Ambroxol*Active N-desmethyl metabolite of bromhexine,systemically active mucolytic agent, Secretomotoric and expectoration improver.*Mechanism of Action of Ambroxol*Ambroxol hydrochloride acts as an expectoration improver and mucolytic agent. It decreases mucus viscosity by altering its structure. It depolymerises mucopolysaccharides directly as well as by liberating lysosomal enzymes and by breaking network of fibres in tenacious sputum . It induces thin copious bronchial secretion and possesses antioxidant properties.
MUCOSIN SR 75mg 10 Caps.AMBROXOLRAMEDA8.5"(Indications):*This medication is a mucolytic agent, prescribed for various respiratory diseases such as emphysema with bronchitis pneumoconiosis, chronic inflammatory pulmonary conditions, tracheobronchitis (respiratory tract inflammation), bronchiectasis, bronchitis with bronchospasm asthma. **(dosage) :* The recommended dose is 30-120 mg/day in 2-3 divided doses.**(Warnings and Precautions) : * Caution needed for pregnant and breastfeeding women.*"
NODEP 10mg 30 f.c.tab.ESCITALOPRAMRAMEDApsychiatric.Antidepressants90About Escitalopram*Selective Serotonin Reuptake Inhibitor (SSRI), Antidepressant.**Mechanism of Action of Escitalopram*Escitalopram is the S enantiomer of racemic Citalopram. It is 100 times more potent than R-enantiomer. Escitalopram blocks the re-uptake of neurotransmitter Serotonin from the synapse to the presynaptic nerve terminal in the CNS. This potentiates the action of Serotonin (5HT) and it is useful in the treatment of depression.**Indications for Escitalopram*Depression.**Typical Dosage for Escitalopram*Adult: Initial dose: 10 mg / day, dose can be increased to 20 mg / day if sufficient response does not occur after a minimum of 1 week.
NORMATEN 50/2.5MG 30 SCORED TABS.CAPTOPRIL -- INDAPAMIDERAMEDAAnti-hypertensive.Combined ACE with diuretic18About Indapamide*Thiazide-related(a non-thiazide sulphonamide) drug, Diuretic, Antihypertensive.*Mechanism of Action of Indapamide*It exerts thiazides like diuretic action by acting at site-3(central dilating segment of early distal tubule). It binds to Na -- Cl- symporter and inhibits Na -- Cl- symport at the luminal membrane. It increases natriuresis, kaliuresis and diuresis. It decreases Ca2 -- excretion and increases Mg2 -- excretion. *It causes vasodilatation by Ca channel blockade. It decreases total peripheral resistance and exerts anti hypertensive action. Decrease in peripheral resistance is due to either the loss of sodium from the arteriolar wall or a direct action on the vascular bed. It is an effective drug in edema associated with congestive heart failure. *Indications for Indapamide*1. Hypertension *2. Oedema *Interactions for Indapamide*Diazoxide: Synergistic action - may cause hyperglycemia, hyperuricaemia and hypotension. *
OCUGENT 3% eye/ear dropsGENTAMICINRAMEDA2.75About Gentamicin*Aminoglycoside antibiotic.**Mechanism of Action of Gentamicin*Gentamicin exerts its bactericidal action against gram negative organisms & some of gram positive organisms by inhibiting bacterial protein synthesis. The process involves 1. Penetration of bacterial cell membrane & binding directly to the bacterial ribosome, 2. Misleading of m-RNA codon by bacterial ribosome, 3. Formation of peptide chains with wrong amino acid sequence which gets incorporated into bacterial cell membrane and alters its permeability, 4. Bacterial cell lysis. Some bacterial strains resistant to other amino glycosides are sensitive to Gentamicin.**Indications for Gentamicin*1. Infections caused by staphylococci, pseudomonas, proteous, klebsiella, enterobacter & serratia. *2. Meningitis. *3. Endocarditis *4. Urinary Tract Infections. *5. Otitis & Ocular infections. *6. Infections of burns & Skin ulcers
OLIPTINA 12.5 MG 30 F.C. TABS.ALOGLIPTINRAMEDAAnti-Diabetic.Secretagogues.DPP-4 inhibitors93Alogliptin is an orally administered anti-diabetic drug in the DPP-4 inhibitor class. Like other medications for the treatment of Type 2 diabetes, alogliptin does not decrease the risk of heart attack and stroke. Like other members of the gliptin class, it causes little or no weight gain, exhibits relatively little risk of causing hypoglycemia, and exhibits relatively modest glucose-lowering activity. Alogliptin and other gliptins are commonly used in combination with metformin in patients whose diabetes cannot adequately be controlled with metformin alone.
OLIPTINA 25 MG 30 F.C. TABS.ALOGLIPTINRAMEDAAnti-Diabetic.Secretagogues.DPP-4 inhibitors153Alogliptin is an orally administered anti-diabetic drug in the DPP-4 inhibitor class. Like other medications for the treatment of Type 2 diabetes, alogliptin does not decrease the risk of heart attack and stroke. Like other members of the gliptin class, it causes little or no weight gain, exhibits relatively little risk of causing hypoglycemia, and exhibits relatively modest glucose-lowering activity. Alogliptin and other gliptins are commonly used in combination with metformin in patients whose diabetes cannot adequately be controlled with metformin alone.
OLIPTINA 6.25 MG 30 F.C. TABS.ALOGLIPTINRAMEDAAnti-Diabetic.Secretagogues.DPP-4 inhibitors63Alogliptin is an orally administered anti-diabetic drug in the DPP-4 inhibitor class. Like other medications for the treatment of Type 2 diabetes, alogliptin does not decrease the risk of heart attack and stroke. Like other members of the gliptin class, it causes little or no weight gain, exhibits relatively little risk of causing hypoglycemia, and exhibits relatively modest glucose-lowering activity. Alogliptin and other gliptins are commonly used in combination with metformin in patients whose diabetes cannot adequately be controlled with metformin alone.
ORDESCA 2.5mg/5ml syp. 120 MLDESLORATADINERAMEDAAnti-histamine.Anti-Allergy9About Desloratadine*Second Generation long-acting tricyclic H1 Antagonist, Antihistamine.**Mechanism of Action of Desloratadine*This second generation antihistamine has a selective peripheral H1-antagonist action.Desloratadine competes with free histamine for binding at H1-receptors in the GI tract, uterus, large blood vessels, and bronchial smooth muscle. This inhibit the action of histamine, which subsequently leads to temporary relief of the negative symptoms brought by histamine**Indications for Desloratadine*1. Hay fever *2. Watery eyes *3. Runny nose *4. Itching eyes *5. Sneezing *6. Hives *7. Decongestant **Typical Dosage for Desloratadine**Adult (general dose)- 5mg/day *Children (-12yrs)-Same as adult
ORDESCA 5mg 20 F.C. TABS.DESLORATADINERAMEDAAnti-histamine.Anti-Allergy16.5About Desloratadine*Second Generation long-acting tricyclic H1 Antagonist, Antihistamine.**Mechanism of Action of Desloratadine*This second generation antihistamine has a selective peripheral H1-antagonist action.Desloratadine competes with free histamine for binding at H1-receptors in the GI tract, uterus, large blood vessels, and bronchial smooth muscle. This inhibit the action of histamine, which subsequently leads to temporary relief of the negative symptoms brought by histamine**Indications for Desloratadine*1. Hay fever *2. Watery eyes *3. Runny nose *4. Itching eyes *5. Sneezing *6. Hives *7. Decongestant **Typical Dosage for Desloratadine**Adult (general dose)- 5mg/day *Children (-12yrs)-Same as adult
ORPHAMOL 20 tab.ORPHENADRIN -- PARACETAMOL(ACETAMINOPHEN)RAMEDACNS.Analgesic.skeletal muscle relaxant.Antimuscarinic5.25About Orphenadrine*Anticholinergic(AntiMuscarinic),ethanolamine H1 antagonist, Anti-Parkinson`s Agent,Centrally acting skeletal muscle relaxent.*Mechanism of Action of Orphenadrine*The exact mechanism of action is not known. A lesion in the Nigra striatum may be responsible for Parkinson`s disease which results in a reduction in Dopamine concentrations. This in turn causes a relative imbalance between dopaminergic and cholinergic neurological pathways. Procyclidine acts by blocking the central muscarinic receptors (M1, M2 and M4 receptors). Thereby it balances cholinergic and dopaminergic action in the basal ganglia. *Skeletal muscle relaxant action: It reduces skeletal muscle spasm by its anticholinergic action on cerebral motor centers. *Orphenadrine binds to both H1 receptor and NMDA receptors. It restores the motor disturbances induced by Neuroleptics
PANCEF 250mg/5ml vial for I.V./I.M. inj.CEFUROXIMERAMEDAAntibiotic.cephalosporin.Second-generation6About Cefuroxime*Second Generation Cephalosporin antibiotic.**Mechanism of Action of Cefuroxime*Cefuroxime is a 2nd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefuroxime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefuroxime **Indications for Cefuroxime*1.Meningitis caused by H.influenzae, meningococci, pneumococci etc. *2.Gonorrhea *3.Pneumonia & Pulmonary infections *4.Infections caused by ampicillin resistant H. influenzae *5.Septicemia *6.Tonsillitis *7.Pharyngitis *8.Urinary tract infections *9.Otitis media
PANCEF 750mg I.M/I.V.vialCEFUROXIMERAMEDAAntibiotic.cephalosporin.Second-generation11About Cefuroxime*Second Generation Cephalosporin antibiotic.**Mechanism of Action of Cefuroxime*Cefuroxime is a 2nd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefuroxime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefuroxime **Indications for Cefuroxime*1.Meningitis caused by H.influenzae, meningococci, pneumococci etc. *2.Gonorrhea *3.Pneumonia & Pulmonary infections *4.Infections caused by ampicillin resistant H. influenzae *5.Septicemia *6.Tonsillitis *7.Pharyngitis *8.Urinary tract infections *9.Otitis media
PIMFAST 1 GM VIAL I.V/I.M inj.CEFEPIMERAMEDAAntibiotic.cephalosporin.Fourth-generation34.25About Cefepime*Fourth Generation cephalosporin antibiotic.**Mechanism of Action of Cefepime*Cefepime is a 3rd generation cephalosporin which exerts its bactericidal action by inhibiting bacterial cell wall synthesis. Cefepime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefipime**Indications for Cefepime*1.Pneumonia *2.Resistant hospital acquired infections *3.Septicemia, *4.Empiric therapy in febrile neutropenic patients *5.Urinary tract infections *6.Pyelonephritis *7.Tonsillitis, Pharyngitis etc. *8.Skin & soft tissue infections
PIMFAST 2 GM VIAL I.V/I.M inj.CEFEPIMERAMEDAAntibiotic.cephalosporin.Fourth-generation48About Cefepime*Fourth Generation cephalosporin antibiotic.**Mechanism of Action of Cefepime*Cefepime is a 3rd generation cephalosporin which exerts its bactericidal action by inhibiting bacterial cell wall synthesis. Cefepime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefipime**Indications for Cefepime*1.Pneumonia *2.Resistant hospital acquired infections *3.Septicemia, *4.Empiric therapy in febrile neutropenic patients *5.Urinary tract infections *6.Pyelonephritis *7.Tonsillitis, Pharyngitis etc. *8.Skin & soft tissue infections
PONAGIC FORTE 500mg 10f.c.tab.MEFENAMIC ACIDRAMEDANSAID.Fenamates3About Mefenamic Acid*NSAID, Analgesic,antiinflammatory.**Mechanism of Action of Mefenamic Acid*Mefenamic acid has analgesic, anti-inflammatory and antipyretic action. It acts by inhibiting Prostaglandin (PGs) synthesis and their release at the site of injury. Prostaglandins cause tenderness and amplify the action of other analgesics. Mefenamic acid inhibits cyclo-oxygenase enzyme and antagonizes prostaglandin actions.**Indications for Mefenamic Acid*1.Muscular aches *2.Primary Dysmenorrhoea *3.Headaches *4.Acute gout *5.Dental pain *6.Patent ductus arteriosus **Typical Dosage for Mefenamic Acid*Adult: initial dose: 500 mg followed by 250 mg every 6 hours. Treatment is continued maximum up to 1 week. *Children above 14 years: *500 mg followed by 250 mg every 6 hours. Treatment is continued maximum up to 1 week. *Children below 14 years: not recommended.
PRIMOMYCIN 400/100 MG 12 Caps.ERYTHROMYCIN -- TRIMETHOPRIMRAMEDA10.5About Erythromycin*Macrolide Antibiotic.*Mechanism of Action of Erythromycin*Erythromycin is a member of macrolide antibiotics. It binds to the 50S sub unit of bacterial ribosome and inhibits translocation.ie: they interfere with the transfer of the newly formed peptide chain from the A site to the P site and fails to expose the A site .So that A site is unable to bind with the next aminoacyl t RNA complex. This leads to premature termination of amino acid chain and there by inhibits protein synthesis.*Interactions for Erythromycin*Anticoagulants: Efficacy enhanced leading to haemorrhages. *Bromocriptine: Efficacy protentiated leading to toxicity. *Carbamazepine: Dangerous toxic side effects requiring resuscitative measures and hospitalisation. *Digoxin: Serum levels of digoxin enhanced, leading to toxicity. *Disopyramide: Increased disopyramide plasma levels leading to arrhythmias. *Ergot Alkaloids: Acute ergotism manifested as peripheral ischaemia. *
PRIMOMYCIN 60ml susp.ERYTHROMYCIN -- TRIMETHOPRIMRAMEDA8.5About Erythromycin*Macrolide Antibiotic.*Mechanism of Action of Erythromycin*Erythromycin is a member of macrolide antibiotics. It binds to the 50S sub unit of bacterial ribosome and inhibits translocation.ie: they interfere with the transfer of the newly formed peptide chain from the A site to the P site and fails to expose the A site .So that A site is unable to bind with the next aminoacyl t RNA complex. This leads to premature termination of amino acid chain and there by inhibits protein synthesis.*Interactions for Erythromycin*Anticoagulants: Efficacy enhanced leading to haemorrhages. *Bromocriptine: Efficacy protentiated leading to toxicity. *Carbamazepine: Dangerous toxic side effects requiring resuscitative measures and hospitalisation. *Digoxin: Serum levels of digoxin enhanced, leading to toxicity. *Disopyramide: Increased disopyramide plasma levels leading to arrhythmias. *Ergot Alkaloids: Acute ergotism manifested as peripheral ischaemia. *
PRISMAVEN 100MG 30 EXTENDED RELEASE TAB.DESVENLAFAXINERAMEDApsychiatric.Antidepressants117It s a serotonin and norepinephrine reuptake inhibitor(SNRI), is indicated for the treatment of major depressive disorder (MDD).*
PRISMAVEN 50MG 30 EXTENDED RELEASE TAB.DESVENLAFAXINERAMEDApsychiatric.Antidepressants90It s a serotonin and norepinephrine reuptake inhibitor(SNRI), is indicated for the treatment of major depressive disorder (MDD).*
PROPHALLERGE 0.025% eye dropsKETOTIFENRAMEDAAnti-histamine.Second-Generation6.5About Ketotifen*Second Generation H1 Antagonist, Mast Cell Stabilizer, Antihistamine.**Mechanism of Action of Ketotifen*It is a mast cell stabilizer. This inhibit the development of airway hyper reactivity (associated with activation of platelets by PAF (Platelet Activating Factor) or caused by neural activation following the use of sympathomimetic drugs or the exposure to allergen) by suppressing the priming of eosinophils by human recombinant cytokines and thereby suppression of the influx of eosinophils into inflammatory site. In addition, Ketotifen is a potent antiallergic substance possessing a powerful and sustained noncompetitive histamine (H 1) blocking property. **Indications for Ketotifen*1. Rhinitis *2. Conjunctivitis *3. Prophylaxis for bronchial asthma *Interactions for Ketotifen*Sedatives, Hypnotics & Alcohol: May potentiate the effects of these agents, leading to CNS depression. *Oral antidiabetics: Avoid as fall in thrombocyte count reported. *
PROPHALLERGE 1mg 20 tabKETOTIFENRAMEDAAnti-histamine.Second-Generation11About Ketotifen*Second Generation H1 Antagonist, Mast Cell Stabilizer, Antihistamine.**Mechanism of Action of Ketotifen*It is a mast cell stabilizer. This inhibit the development of airway hyper reactivity (associated with activation of platelets by PAF (Platelet Activating Factor) or caused by neural activation following the use of sympathomimetic drugs or the exposure to allergen) by suppressing the priming of eosinophils by human recombinant cytokines and thereby suppression of the influx of eosinophils into inflammatory site. In addition, Ketotifen is a potent antiallergic substance possessing a powerful and sustained noncompetitive histamine (H 1) blocking property. **Indications for Ketotifen*1. Rhinitis *2. Conjunctivitis *3. Prophylaxis for bronchial asthma *Interactions for Ketotifen*Sedatives, Hypnotics & Alcohol: May potentiate the effects of these agents, leading to CNS depression. *Oral antidiabetics: Avoid as fall in thrombocyte count reported. *
PROPHALLERGE 1mg/5ml 120ml syrupKETOTIFENRAMEDAAnti-histamine.Second-Generation11About Ketotifen*Second Generation H1 Antagonist, Mast Cell Stabilizer, Antihistamine.**Mechanism of Action of Ketotifen*It is a mast cell stabilizer. This inhibit the development of airway hyper reactivity (associated with activation of platelets by PAF (Platelet Activating Factor) or caused by neural activation following the use of sympathomimetic drugs or the exposure to allergen) by suppressing the priming of eosinophils by human recombinant cytokines and thereby suppression of the influx of eosinophils into inflammatory site. In addition, Ketotifen is a potent antiallergic substance possessing a powerful and sustained noncompetitive histamine (H 1) blocking property. **Indications for Ketotifen*1. Rhinitis *2. Conjunctivitis *3. Prophylaxis for bronchial asthma *Interactions for Ketotifen*Sedatives, Hypnotics & Alcohol: May potentiate the effects of these agents, leading to CNS depression. *Oral antidiabetics: Avoid as fall in thrombocyte count reported. *
RAMALLERGE 4mg 20tab.CARBINOXAMINERAMEDA4.5About Carbinoxamine maleate*H1 receptor antagonist, Ethanolamine antihistamines, anticholinergic, Antihistamine.*Mechanism of Action of Carbinoxamine maleate*Carbinoxamine maleate exerts it`s action by acting as an H1 receptor antagonist. It antagonizes most of the pharmacological actions of Histamine and reduces allergic symptoms. It also has anticholinergic properties and reduces secretions.
RAMECEFTRAX 1GM IM VIALCEFTRIAXONERAMEDAAntibiotic.cephalosporin.third-generation23.5About Ceftriaxone*Third Generation Cephalosporin antibiotic(Parenteral).**Mechanism of Action of Ceftriaxone*Ceftriaxone is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Ceftriaxone inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Ceftriaxone. **Indications for Ceftriaxone*1.Meningitis *2.Septicaemia *3.Typhoid *4.UTI *5.Prophylaxis in surgical infections *6.Lower respiratory tract infections *7.Pneumonia *8.Pelvic inflammatory disease *9.STD *10.Bacteraemia
RAMECEFTRAX 1GM IV VIALCEFTRIAXONERAMEDAAntibiotic.cephalosporin.third-generation23.5About Ceftriaxone*Third Generation Cephalosporin antibiotic(Parenteral).**Mechanism of Action of Ceftriaxone*Ceftriaxone is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Ceftriaxone inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Ceftriaxone. **Indications for Ceftriaxone*1.Meningitis *2.Septicaemia *3.Typhoid *4.UTI *5.Prophylaxis in surgical infections *6.Lower respiratory tract infections *7.Pneumonia *8.Pelvic inflammatory disease *9.STD *10.Bacteraemia
RAMECEFTRAX 500 MG vial for I.M. inj.CEFTRIAXONERAMEDAAntibiotic.cephalosporin.third-generation20.75About Ceftriaxone*Third Generation Cephalosporin antibiotic(Parenteral).**Mechanism of Action of Ceftriaxone*Ceftriaxone is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Ceftriaxone inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Ceftriaxone. **Indications for Ceftriaxone*1.Meningitis *2.Septicaemia *3.Typhoid *4.UTI *5.Prophylaxis in surgical infections *6.Lower respiratory tract infections *7.Pneumonia *8.Pelvic inflammatory disease *9.STD *10.Bacteraemia
RAMECEFTRAX 500 MG vial for I.V. inj.CEFTRIAXONERAMEDAAntibiotic.cephalosporin.third-generation16.5About Ceftriaxone*Third Generation Cephalosporin antibiotic(Parenteral).**Mechanism of Action of Ceftriaxone*Ceftriaxone is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Ceftriaxone inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Ceftriaxone. **Indications for Ceftriaxone*1.Meningitis *2.Septicaemia *3.Typhoid *4.UTI *5.Prophylaxis in surgical infections *6.Lower respiratory tract infections *7.Pneumonia *8.Pelvic inflammatory disease *9.STD *10.Bacteraemia
RAMEDAMYCIN 0.3% ophth. soln. 5 MLTOBRAMYCINRAMEDA6About Tobramycin*Aminoglycoside derivative, Antibiotic.*Mechanism of Action of Tobramycin*Tobramycin exerts its bactericidal action against gram- negative organisms & some of gram positive organisms by inhibiting bacterial protein synthesis. The process involves 1. Penetration of bacterial cell membrane & binding directly to the bacterial ribosome, 2. Misleading of m-RNA codon by bacterial ribosome, 3. Formation of peptide chains with wrong amino acid sequence which gets incorporated into bacterial cell membrane and alters its permeability, 4. Bacterial cell lysis. Some bacterial strains like pseudomonas are more sensitive to Tobramycin than Gentamicin.*Indications for Tobramycin*1. Infections caused by pseudomonas, proteous, staphylococcus, klebsiella, E coli, serratia, enterobacter etc *2. Cystic fibrosis with pseudomonas infections: *3. Ocular infections *4. Gastro intestinal diseases *5. Urinary tract infections *6. Endocarditis *7. Meningitis*
RAMEDAMYCIN PLUS eye drops 5 MLDEXAMETHASONE -- TOBRAMYCINRAMEDA7About Dexamethasone*A potent synthetic glucocorticoid, Antiasthmatic, anti-inflammatory and immunosuppressant.*Mechanism of Action of Dexamethasone*The drug exerts it`s pharmacological action by penetrating and binding to cytoplasmic receptor protein and causes a structural change in steroid receptor complex. This structural change allows it`s migration in to the nucleus and then binding to specific sites on the DNA which leads to transcription of specific m-RNA and which ultimately regulates protein synthesis. It exerts highly selective glucocorticoid action. It stimulates the enzymes needed to decrease the inflammatory response. *The drug exerts anti-inflammatory and immunosuppressant actions as follows: - 1) Induce lipocortins in macrophages, endothelium, and fibroblasts which inhibits phospholipase A2 and thus decreases the production of Prostaglandins, leukotriens (LT), and platelet activating factor, 2) Causes negative regulation of genes for cytokines in macrophages, endothe
RAMEDAZOLAMIDE eye dropDORZOLAMIDE -- TIMOLOLRAMEDA45About Dorzolamide*Carbonic anhydrase inhibitor, Thiophene derivative, a sulfonamide, Antiglucoma.*Mechanism of Action of Dorzolamide*Dorzolamide is a sulfonamide used as topical carbonic anhydrase inhibitor. Inhibition of carbonic anhydrase-2 in ciliary processes of eye leads to reducing intra ocular tension by decreasing aqueous humor secretion by slowing the formation of bicarbonate ions with subsequent decrease in sodium and fluid transport.*About Timolol*Nonselective Beta Adrenergic,Blocker,Ophthalmic- Antiglaucoma,antimigraine.*Mechanism of Action of Timolol*Timolol is a non selective beta blocker. It inhibits the beta receptors (?2) present in the eye such as in the ciliary body epithelium and blood vessels. This will leads to decreased aqueous production and reduced intraocular pressure. Aqueous humor production is activated by ? receptor mediated cyclic AMP phosphokinase pathway. Beta receptor blockers will decreases the intracellular cyclic AMP level and reduces intraoc
RAME-DINIR 125MG/5ML PWD FOR ORAL SUSP.CEFDINIRRAMEDAAntibiotic.cephalosporin.third-generation36About Cefdinir*Semisynthetic (Third Generation ) cephalosporin antibiotic, Oral broad-spectrum antibiotic.**Mechanism of Action *Cefdinir is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & aerobic gram negative organisms by inhibiting bacterial cell wall synthesis. Cefdinir inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefdinir**Indications for Cefdinir*1.Pneumonia *2.Bronchitis *3.Pharyngitis *4.Tonsillitis *5.Skin & soft tissue infections *6.Otitismedia *7.Sinusitis
RAME-DINIR 250MG/5ML PWD FOR ORAL SUSP.CEFDINIRRAMEDAAntibiotic.cephalosporin.third-generation48About Cefdinir*Semisynthetic (Third Generation ) cephalosporin antibiotic, Oral broad-spectrum antibiotic.**Mechanism of Action *Cefdinir is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & aerobic gram negative organisms by inhibiting bacterial cell wall synthesis. Cefdinir inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefdinir**Indications for Cefdinir*1.Pneumonia *2.Bronchitis *3.Pharyngitis *4.Tonsillitis *5.Skin & soft tissue infections *6.Otitismedia *7.Sinusitis
RAMEFLUZOLE 150mg 1 Caps.FLUCONAZOLERAMEDAantifungals.Triazoles9.25About Fluconazole*A triazole derivative, A board range Antifungal.**Mechanism of Action of Fluconazole*Fluconazole is fungicidal or fungistatic depending on the drug concentrations. I t inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochromeP450 enzyme 14 alpha demethylase and impair ergosterol synthesis**Interactions for Fluconazole*Cimetidine: Decreased efficacy of fluconazole. *Cyclosporine: Increase in serum cyclosporine plasma concentration. *Hydrochlorothiazide: Reduction in renal clearance of fluconazole. *Phenytoin: Efficacy of phenytoin enhanced. *Rifampicin: Efficacy of fluconazole decreased, higher dosage required. *Sulfonylureas: Efficacy of tolbutamide, glyburide and glipizide increased. *Warfarin: Potentiates the anticoagulant effect resulting in increase in prothrombin time. **Indications for Fluconazole*1.Oesophageal candidiasis *2.Oropharyngeal candidiasis *3.Vaginal candidiasis *4.Systemic candidiasis *5.Cryptoc
RAMENART 600 MG 10 F.C. TABSTELBIVUDINERAMEDAAnti-Viral.Nucleoside131Telbivudine is an antiviral drug used in the treatment of hepatitis B infection. *Telbivudine is a synthetic thymidine BETA-L-nucleoside analogue- it is the L-isomer of thymidine. Telbivudine impairs hepatitis B virus (HBV) DNA replication by leading to chain termination. It differs from the natural nucleotide only with respect to the location of the sugar and base moieties, taking on an levorotatory configuration versus a dextrorotatory configuration as do the natural deoxynucleosides. It is taken orally in a dose of 600 mg once daily with or without food.
RAMETAX 1gm I.V./I.M vialCEFOTAXIMERAMEDAAntibiotic.cephalosporin.third-generation17.25About Cefotaxime*Third Generation cephalosporin Parenteral antibiotic.**Mechanism of Action of Cefotaxime*Cefotaxime is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & aerobic gram negative organisms by inhibiting bacterial cell wall synthesis. Cefotaxime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefotaxime**Indications for Cefotaxime*1.Meningitis *2.Resistant hospital acquired infections *3.Septicemia *4.Infections in immunocompromised patients *5.Urinary tract &genital tract infections *6.Surgical prophylaxis *7.Skin & soft tissue infections *8.Bone & Joint infections *9.Gonorrhea. **Interactions for Cefotaxime*Synergy with aminoglycosides.
RAMETAX 500 MG I.V/I.M vialCEFOTAXIMERAMEDAAntibiotic.cephalosporin.third-generation12.75About Cefotaxime*Third Generation cephalosporin Parenteral antibiotic.**Mechanism of Action of Cefotaxime*Cefotaxime is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & aerobic gram negative organisms by inhibiting bacterial cell wall synthesis. Cefotaxime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefotaxime**Indications for Cefotaxime*1.Meningitis *2.Resistant hospital acquired infections *3.Septicemia *4.Infections in immunocompromised patients *5.Urinary tract &genital tract infections *6.Surgical prophylaxis *7.Skin & soft tissue infections *8.Bone & Joint infections *9.Gonorrhea. **Interactions for Cefotaxime*Synergy with aminoglycosides.
RAME-ZITHRO 200mg/5ml 15ml susp.AZITHROMYCINRAMEDAAntibiotic.Macrolide12"Description: *Azithromycin is a semi-synthetic macrolide antibiotic of the azalide class.**dose:*Adult: PO- Respiratory tract, Skin and soft tissue infections- 500 mg once daily for 3 days. Or 500mg on day 1 followed by 250mg on days 2 to 5. *Typhoid- 500 mg once daily for 7 days. *Uncomplicated gonorrhoea- 2 g single dose. *Granuloma inguinale- Initial: 1 g, then 500 mg/day until all lesions has healed completely.*Chancroid/Chlamydial urethritis: 1 g single dose Prophylaxis of disseminated MAC infections 1.2 g once weekly. Treatment or secondary prophylaxis: administered along with other antimycobacterials: 500 mg once daily. **Mechanism of action Azithromycin binds to the 50S subunit of the 70S bacterial ribosomes, and therefore inhibits RNA-dependent protein synthesis in bacterial cells.**Half life :*68 hours"
SUPER ACT 20 Caps.CAFFEINE -- NICOTINIC ACID -- VITAMIN E -- YOHIMBINERAMEDASexual tonic13.2
SYNCHROGIT 10mg 20 tab.DOMPERIDONERAMEDA8About Domperidone*Antidopaminergic, Motility stimulant,Piperidine derivative, Antiemetic, anti-vertigo.*Mechanism of Action of Domperidone*Domperidone is a potent dopamine receptor antagonist. It acts centrally and blocks the Dopamine receptor in the Chemoreceptor trigger zone and produces Antiemetic effect. *Domperidone acts peripherally in the gastrointestinal system and increases oesophageal peristalsis, oesophageal sphincter pressure and gastric motility. These all facilitates gastric emptying. Domperidone is used in migraine to relieve nausea and vomiting. *Anaesthetic adjuncts: It is used preoperatively in order to reduce the post operative vomiting. **Indications for Domperidone*1.Nausea and vomiting associated with gastrointestinal disorder and migraine. *2.Delayed gastric emptying of functional origin *3.As an Antiemetic in patient receiving cytotoxic drugs *4.Preanaesthetic medication
TAMSUNORM S.R. 0.4mg 30 Caps.TAMSULOSINRAMEDAUrination-difficulty.Alpha Blocker37.5About Tamsulosin*Selective Alpha1a Adrenergic Antagonist , For benign prostatic hyperplasia.*Mechanism of Action of Tamsulosin*Tamsulosin is adrenergic alpha receptor antagonist. It inhibits alpha 1A and alpha 1D subtype receptors. Tamsulosin selectively inhibits alpha 1A receptor in the prostate and leads to relaxation of smooth muscles in the bladder neck and prostate. This will improve urine flow and reduces BPH symptoms. *Adrenergic nerves releases adrenalin which produces contraction of muscles. Tamsulosin is selectively inhibit alpha 1A receptor in the prostate and bladder neck and relaxes the muscles and decrease the obstruction to the flow of urine in prostate hypertrophy. *Indications for Tamsulosin*1. Benign Prostatic hyperplasia (BPH) ***Interactions for Tamsulosin*Cimetidine: Results in significant decrease in clearance of tamsulosin AUC. *Alpha adrenergic blocking agents: Tamsulosin should not be used in combination with other alpha adrenergics.
TAZOX 50mg 30 tab.CILOSTAZOLRAMEDAAntiplatlet.phosphodiesterase 3 inhibitor66"Description *Cilostazol is a medication used in the alleviation of the symptom of intermittent claudication in individuals with peripheral vascular disease. It is manufactured by Otsuka Pharmaceutical Co. under the trade name Pletal. Although drugs similar to cilostazol have increased the risk of death in patients with congestive heart failure, studies of significant size have not addressed people without the disease***Mechanism of action Cilostazol and several of its metabolites are cyclic AMP (cAMP) phosphodiesterase III inhibitors (PDE III inhibitors), inhibiting phosphodiesterase activity and suppressing cAMP degradation with a resultant increase in cAMP in platelets and blood vessels, leading to inhibition of platelet aggregation and vasodilation."
TOLEVO M.R. 4mg 30 CAPS.TOLTERODINE L TARTARATERAMEDAUrinary incontinence.Antispasmodics.Muscarinic Antagonists60About Tolterodine Tartarate*Anticholinergic ( antimuscarinic), Treat urinary incontinence.*Mechanism of Action of Tolterodine Tartarate*Tolterodine tartrate is a specific muscarinic receptor (M3 receptor) antagonist. It blocks muscarinic receptors which can be found on the muscle cells of the bladder wall. It prevents the action of acetyl choline on these receptors. Acetylcholine acting on these receptors causes the muscle in the bladder wall to contract, and the bladder to empty. By preventing this, Tolterodine helps the muscle in the bladder wall to relax. This reduces unstable, involuntary contractions of the bladder, and thereby increases the capacity of the bladder to hold urine. This in turn reduces the need to pass urine. *Stimulation of muscarinic receptors causes the bladder to contract and empty. Tolterodine relax the involuntary muscle in the wall of the bladder.
TREXOTAZ 1.5g I.M. / I.V. VIALCEFOPERAZONE -- SULBACTAMRAMEDA30Indications for Cefoperazone Sodium -- Sulbactam Sodium*It is a combination of third generation Cephalosporins Cefperazone sodium and Beta-lactamase inhibitor Sulbactam. *1.Pharyngitis *2.Tonsillitis *3.Pneumonia *4.Bronchitis *5.Other respiratory tract infections *6.Septicemia *7.Meningitis *8.Urinogenital tract infections *9.Bone & Joint infections *10.Gonorrhea *11.Endometritis *12.Skin & Soft tissue infections *13.Pelvic inflammatory diseases *14.Intra abdominal infections *About Cefoperazone Sodium*A third generation cephalosporin antibiotic, Parenteral antibiotic.*About Sulbactam Sodium*An irreversible ?-lactamase inhibitor, To increase the antibacterial activity of penicillins and cephalosporins against ?-lactamase?producing organisms.
TREXOTAZ 2g I.M. / I.V. VIALCEFOPERAZONE -- SULBACTAMRAMEDA35Indications for Cefoperazone Sodium -- Sulbactam Sodium*It is a combination of third generation Cephalosporins Cefperazone sodium and Beta-lactamase inhibitor Sulbactam. *1.Pharyngitis *2.Tonsillitis *3.Pneumonia *4.Bronchitis *5.Other respiratory tract infections *6.Septicemia *7.Meningitis *8.Urinogenital tract infections *9.Bone & Joint infections *10.Gonorrhea *11.Endometritis *12.Skin & Soft tissue infections *13.Pelvic inflammatory diseases *14.Intra abdominal infections *About Cefoperazone Sodium*A third generation cephalosporin antibiotic, Parenteral antibiotic.*About Sulbactam Sodium*An irreversible ?-lactamase inhibitor, To increase the antibacterial activity of penicillins and cephalosporins against ?-lactamase?producing organisms.
TRICARDIA 20mg 90 tabTRIMETAZIDINERAMEDAAnti-Ischemic42About Trimetazidine*Cytoprotective,vasodilator, Anti-ischemic (anti-anginal) agent.*Mechanism of Action of Trimetazidine*It is a cytoprotective drug which reduces anginal attacks and improves exercise tolerance by nonhaemodynamic mechanisms. It improves cellular tolerance to ischaemia by: - 1) Inhibiting mitochondrial long chain 3-ketoacyl-CoA-thiolase- a key enzyme in fatty acid oxidation and there by reducing fatty acid metabolism and increasing glucose metabolism in myocardium. 2) Limiting intracellular acidosis and sodium and calcium accumulation during ischaemia. 3) Protecting against O* free radical induced membrane damage
TRICARDIA MR 35mg 30 F.C. TABS.TRIMETAZIDINERAMEDAAnti-Ischemic19About Trimetazidine*Cytoprotective,vasodilator, Anti-ischemic (anti-anginal) agent.*Mechanism of Action of Trimetazidine*It is a cytoprotective drug which reduces anginal attacks and improves exercise tolerance by nonhaemodynamic mechanisms. It improves cellular tolerance to ischaemia by: - 1) Inhibiting mitochondrial long chain 3-ketoacyl-CoA-thiolase- a key enzyme in fatty acid oxidation and there by reducing fatty acid metabolism and increasing glucose metabolism in myocardium. 2) Limiting intracellular acidosis and sodium and calcium accumulation during ischaemia. 3) Protecting against O* free radical induced membrane damage
VETOYAGRA 100 mg 5 F.C. tabs.SILDENAFILRAMEDASexual tonic12About Sildenafil Citrate*Phosphodiesterase-5 Enzyme Inhibitor, Anti-erectile dysfunction agent.*Mechanism of Action of Sildenafil Citrate*Sildenafil is a phosphodiesterase enzyme (PDE5) inhibitor. This enzyme is responsible for the degradation cyclic guanosine monophosphate (cGMP) produced in reaction to sexual stimulation. The more cGMP is available, the more durable the erection. Sildenafil inhibits the PDE5 enzyme, preserving cGMP levels, therefore aiding erection viability and durability *Erection of the penis is caused by the filling of the penis with blood. Filling occurs because the blood vessels that bring blood to the penis increase in size and deliver more blood to the penis and at the same time, the blood vessels that take blood away from the penis decrease in size and remove less blood from the penis. *Sexual stimulation that leads to an erection causes the production and release of nitric oxide in the corpora cavernosa of the penis.
VETOYAGRA 50 mg 5 F.C. tabs.SILDENAFILRAMEDASexual tonic9.5About Sildenafil Citrate*Phosphodiesterase-5 Enzyme Inhibitor, Anti-erectile dysfunction agent.*Mechanism of Action of Sildenafil Citrate*Sildenafil is a phosphodiesterase enzyme (PDE5) inhibitor. This enzyme is responsible for the degradation cyclic guanosine monophosphate (cGMP) produced in reaction to sexual stimulation. The more cGMP is available, the more durable the erection. Sildenafil inhibits the PDE5 enzyme, preserving cGMP levels, therefore aiding erection viability and durability *Erection of the penis is caused by the filling of the penis with blood. Filling occurs because the blood vessels that bring blood to the penis increase in size and deliver more blood to the penis and at the same time, the blood vessels that take blood away from the penis decrease in size and remove less blood from the penis. *Sexual stimulation that leads to an erection causes the production and release of nitric oxide in the corpora cavernosa of the penis.


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