PHARCO

Company Information

History :  Pharco Pharmaceuticals is the founder member of Pharco Corporation, founded by Dr. Hassan Abbas Helmy, started operation in 1987.Pharco Corporation is a group of nine health care companies operating in the pharmaceutical field for development,manufacturing,marketing, distributing and exporting of a comprehensive array of branded and generic drugs, together with a rising number of licensed pharmaceutical products.Today Pharco employs 5700 employees, and boasts over 345 Million units in sales, ranking number one in the Egyptian pharmaceutical market, with 13.2% market share in 2011. Pharco exports to 57 countries around the globe. Pharco works towards one goal, to provide highly effective, safe pharmaceutical products to patients at an affordable price.

Logo

  • No. of Employees: 5000 - 10000

  • Range of expected salary for med. Rep.: After Interview

  • Car policy: yes

  • Incentive scheme: yes

  • factory: yes

  • Company rank (IMS) 2018: 4

  • Company link: https://www.pharco.org/

Products

Trade NameGeneric NameCompanyPharmacology PriceDescription
ACNE ZINC topical solution 20 MLERYTHROMYCIN -- ZINC ACETATEPHARCO8.5About Erythromycin*Macrolide Antibiotic.*Mechanism of Action of Erythromycin*Erythromycin is a member of macrolide antibiotics. It binds to the 50S sub unit of bacterial ribosome and inhibits translocation.ie: they interfere with the transfer of the newly formed peptide chain from the A site to the P site and fails to expose the A site .So that A site is unable to bind with the next aminoacyl t RNA complex. This leads to premature termination of amino acid chain and there by inhibits protein synthesis.*Indications for Erythromycin*1.Tonsilitis *2.Pharyngitis *3.Pneumonia *4.Diphtheria *5.Pertusis *6.Tetanus *7.SABE *8.Syphilis *9.Gonorrhea *10.Wound and burn infection *11.Rheumatic fever *12.Acne *13.Urogenital infection *14.Chancroid *15.Intestinal amoebiasis *16.Skin and soft tissue infections *17.Urethritis
ADOLOR 10 mg 20 F.C. Tab.KETOROLAC TROMETHAMINEPHARCONSAID.Acetic acid derivatives12.75"Mechanism of action Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) chemically related to indomethacin and tolmetin. Ketorolac tromethamine is a racemic mixture of [-]S- and [plus]R-enantiomeric forms, with the S-form having analgesic activity. Its antiinflammatory effects are believed to be due to inhibition of both cylooxygenase-1 (COX-1) and cylooxygenase-2 (COX-2) which leads to the inhibition of prostaglandin synthesis leading to decreased formation of precursors of prostaglandins and thromboxanes from arachidonic acid. The resultant reduction in prostaglandin synthesis and activity may be at least partially responsible for many of the adverse, as well as the therapeutic, effects of these medications. Analgesia is probably produced via a peripheral action in which blockade of pain impulse generation results from decreased prostaglandin activity."
ADOLOR 15 MG 3 AMPKETOROLAC TROMETHAMINEPHARCO7.5About Ketorolac*NSAID, heterocyclic acetic acid derivative, Analgesic,antipyretic,antiinflammatory.**Mechanism of Action of Ketorolac*This Non Steroidal Anti Inflammatory Drug`s peripheral analgesics action is by the reduction of the prostaglandin synthesis which mediates many of the inflammatory changes and fever at that time. Prostaglandin synthesis is reduced due to its cyclo oxygenase inhibition. At higher concentration it reduce production of super oxide radicals, induce apoptosis, inhibit the expression of adhesion molecules, decrease nitric oxide synthase , reduce pro inflammatory cytokines, modify lymphocyte activity, and alter cellular membrane functions.**Interactions for Ketorolac*Anticoagulants: May prolong prothrombin time. *Beta blockers: Antihypertensive effect may be impaired. *Cyclosporine: Nephrotoxicity of both agents may be increased. *Lithium: Serum lithium levels may be increased resulting in toxicity. *
ADOLOR 30 MG 3 AMPKETOROLAC TROMETHAMINEPHARCO12About Ketorolac*NSAID, heterocyclic acetic acid derivative, Analgesic,antipyretic,antiinflammatory.**Mechanism of Action of Ketorolac*This Non Steroidal Anti Inflammatory Drug`s peripheral analgesics action is by the reduction of the prostaglandin synthesis which mediates many of the inflammatory changes and fever at that time. Prostaglandin synthesis is reduced due to its cyclo oxygenase inhibition. At higher concentration it reduce production of super oxide radicals, induce apoptosis, inhibit the expression of adhesion molecules, decrease nitric oxide synthase , reduce pro inflammatory cytokines, modify lymphocyte activity, and alter cellular membrane functions.**Interactions for Ketorolac*Anticoagulants: May prolong prothrombin time. *Beta blockers: Antihypertensive effect may be impaired. *Cyclosporine: Nephrotoxicity of both agents may be increased. *Lithium: Serum lithium levels may be increased resulting in toxicity. *
ALERTIN 20 TABS.CAFFEINE--ETHAMIVANPHARCOCNS.Stimulant8
ALGASON MASSAGE cream 40 GMCAMPHOR -- DIETHYLAMINE SALICYLATE--MENTHOLPHARCO10.5Mechanism of Action of Camphor*Camphor acts as a rubefacient when it is rubbed on the skin and causes localized vasodilatation- which gives feelings of comfort and warmth. When applied gently on the skin, it acts as an anti-pruritic agent and creates a feeling of coolness, and a mild local anaesthetic effect and relieves itching. When ingested in small amounts, it creates feelings of warmth and comfort in the epigastrium. Camphor acts as a local anesthetic on the respiratory passageways and causing cough suppression.*Pharmacokinets of Camphor*Absorption: Well absorbed through the skin, Distribution: Widely distributed in the body and crosses the placenta, Metabolism: Metabolized in liver, Excretion: Excreted mainly through urine and a minor portion is excreted through lungs.
AMFLUX 1g vialAMOXICILLIN--FLUCLOXACILLINPHARCOPenicillins.Penicillin with B-lactamase inhbitor7.25"amoxycillin and flucloxacillin - generally exhibit an additive effect against sensitive bacteria and bacteria that are sensitive to amoxycillin or to flucloxacillin remain sensitive to the combination, showing that antagonism does not occur when the two components are combined.*Typical indications include:*Acute and chronic bronchitis *Pelvic inflammatory disease*Pneumonia *Urinary tract infections*Ear, nose and throat infections Skin and soft tissue infections*Gynaecological infections"
AMFLUX 500mg vialAMOXICILLIN--FLUCLOXACILLINPHARCOPenicillins.Penicillin with B-lactamase inhbitor5.5"amoxycillin and flucloxacillin - generally exhibit an additive effect against sensitive bacteria and bacteria that are sensitive to amoxycillin or to flucloxacillin remain sensitive to the combination, showing that antagonism does not occur when the two components are combined.*Typical indications include:*Acute and chronic bronchitis *Pelvic inflammatory disease*Pneumonia *Urinary tract infections*Ear, nose and throat infections Skin and soft tissue infections*Gynaecological infections"
AMPIFLUX 250mg/5ml 60ml susp.AMPICILLIN -- FLUCLOXACILLINPHARCOPenicillins.Penicillin with B-lactamase inhbitor11.75This medicine contains 2 antibiotics called Flucloxacillin and Ampicillin.**This combination of Flucloxacillin and Ampicillin is also known as Co-Fluampicil. This medicine belongs to a group of antibiotics called the penicillins.**Co-Fluampicil is used to treat certain bacterial infections of the ear, nose, throat, lungs, skin or bladder.**interaction:*Do not take antacids together with Co-Fluampicil. Antacids could reduce the effectiveness of Co-Fluampicil. If you must take antacids, take them at least 1 hour before or 2 hours after Co-Fluampicil.**Inform your doctor if you are taking birth-control pills that contain oestrogen. Co-Fluampicil may decrease the effectiveness of these pills. You may wish to discuss additional birth-control methods with your doctor or pharmacist.
AMPIFLUX 500mg 12 Caps.AMPICILLIN -- FLUCLOXACILLINPHARCOPenicillins.Penicillin with B-lactamase inhbitor12This medicine contains 2 antibiotics called Flucloxacillin and Ampicillin.**This combination of Flucloxacillin and Ampicillin is also known as Co-Fluampicil. This medicine belongs to a group of antibiotics called the penicillins.**Co-Fluampicil is used to treat certain bacterial infections of the ear, nose, throat, lungs, skin or bladder.**interaction:*Do not take antacids together with Co-Fluampicil. Antacids could reduce the effectiveness of Co-Fluampicil. If you must take antacids, take them at least 1 hour before or 2 hours after Co-Fluampicil.**Inform your doctor if you are taking birth-control pills that contain oestrogen. Co-Fluampicil may decrease the effectiveness of these pills. You may wish to discuss additional birth-control methods with your doctor or pharmacist.
ANAHAL 100% inhalation solution 100 MLISOFLURANEPHARCO150"Description *A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.**Mechanism of action *Isoflurane induces a reduction in junctional conductance by decreasing gap junction channel opening times and increasing gap junction channel closing times. Isoflurane also activates calcium dependent ATPase in the sarcoplasmic reticulum by increasing the fluidity of the lipid membrane. Also appears to bind the D subunit of ATP synthase and NADH dehydogenase. Isoflurane also binds to the GABA receptor, the large conductance Ca2 activated potassium channel, the glutamate receptor and the glycine receptor."
ANAHAL 100% inhalation solution 250 MLISOFLURANEPHARCO220"Description *A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.**Mechanism of action *Isoflurane induces a reduction in junctional conductance by decreasing gap junction channel opening times and increasing gap junction channel closing times. Isoflurane also activates calcium dependent ATPase in the sarcoplasmic reticulum by increasing the fluidity of the lipid membrane. Also appears to bind the D subunit of ATP synthase and NADH dehydogenase. Isoflurane also binds to the GABA receptor, the large conductance Ca2 -- activated potassium channel, the glutamate receptor and the glycine receptor."
ANTHELMIN 0.6gm/30ml 30ml susp.MEBENDAZOLEPHARCOAnthelmintic3.5About Mebendazole*A benzimidazole derivative, Anthelmintic.**Mechanism of Action of Mebendazole*Mebendazole is a benzimidazole used as a broad spectrum anthelminthic which acts by blocking glucose uptake in the parasite and depletion of its glycogen stores. Intracellular microtubules in the cells of the worm are gradually lost. The drug binds to beta tubulin of susceptible worms with high affinity and inhibits its polymerization. Ascaris ova are killed. It also inhibits hatching of nematode eggs and larvae.*Indications for Mebendazole*1. Ascariasis *2. Pinworm infection *3. Hook worm infection *4. Tape worm infection *5. Whip worm infections *6. Threadworm infections *7. Hydatid disease *8. Cappillariasis *9. Mixed infestation **
ASCORBOVIT 1gm 6 sachetsVITAMIN CPHARCO5About Vitamin C*Water soluble vitamin, antioxidant.*Mechanism of Action of Vitamin C*Vitamin C exerts it`s action by influencing the biologic oxidations and reductions used in cellular respirations. It directly stimulates collagen synthesis and maintains intracellular connective tissue. It involves in various metabolic reactions such as 1).Hydroxylation of praline and lysine residues of protocollagen which is essential for formation and stabilization of collagen triple helix, 2).hydroxylation of carnitine, 3).Conversion of folic acid to folinic acid, 4).biosynthesis of adrenal steroids, catecholamines, oxytocin, and ADH, 5).Metabolism of cyclic nucleotides and prostaglandins. Vitamin C is important in resistance to infections.*Interactions for Vitamin C*Oral contraceptives and estrogens: Vitamin C increases serum levels of oestrogen resulting in adverse reactions . *Warfarin: The anticoagulant effects of warfarin is reduced. *Lab Tests: Large doses (-500 mg) of vitamin C may ca*
ATELOL 100mg 20 tab.ATENOLOLPHARCOAnti-hypertensive.Beta blocker.Selective B110"Description : *A cardioselective beta-adrenergic blocker possessing properties and potency similar to propranolol, but without a negative inotropic effect.**dose:*Adult: PO- Angina pectoris- HTN- 50-100 mg once daily. Migraine prophylaxis 50-100 mg/day. **Indication :*For the management of hypertention and long-term management of patients with angina pectoris**Mechanism of action:*Like metoprolol, atenolol competes with sympathomimetic neurotransmitters such as catecholamines for binding at beta(1)-adrenergic receptors in the heart and vascular smooth muscle, inhibiting sympathetic stimulation. This results in a reduction in resting heart rate, cardiac output, systolic and diastolic blood pressure, and reflex orthostatic hypotension. Higher doses of atenolol also competitively block beta(2)-adrenergic responses in the bronchial and vascular smooth muscles.*"
ATELOL 50mg 20 tab.ATENOLOLPHARCOAnti-hypertensive.Beta blocker.Selective B17.5"Description : *A cardioselective beta-adrenergic blocker possessing properties and potency similar to propranolol, but without a negative inotropic effect.**dose:*Adult: PO- Angina pectoris- HTN- 50-100 mg once daily. Migraine prophylaxis 50-100 mg/day. **Indication :*For the management of hypertention and long-term management of patients with angina pectoris**Mechanism of action:*Like metoprolol, atenolol competes with sympathomimetic neurotransmitters such as catecholamines for binding at beta(1)-adrenergic receptors in the heart and vascular smooth muscle, inhibiting sympathetic stimulation. This results in a reduction in resting heart rate, cardiac output, systolic and diastolic blood pressure, and reflex orthostatic hypotension. Higher doses of atenolol also competitively block beta(2)-adrenergic responses in the bronchial and vascular smooth muscles.*"
AZOMYCIN 200mg/5ml 15ml susp.AZITHROMYCINPHARCOAntibiotic.Macrolide15.6"Description: *Azithromycin is a semi-synthetic macrolide antibiotic of the azalide class.**dose:*Adult: PO- Respiratory tract, Skin and soft tissue infections- 500 mg once daily for 3 days. Or 500mg on day 1 followed by 250mg on days 2 to 5. *Typhoid- 500 mg once daily for 7 days. *Uncomplicated gonorrhoea- 2 g single dose. *Granuloma inguinale- Initial: 1 g, then 500 mg/day until all lesions has healed completely.*Chancroid/Chlamydial urethritis: 1 g single dose Prophylaxis of disseminated MAC infections 1.2 g once weekly. Treatment or secondary prophylaxis: administered along with other antimycobacterials: 500 mg once daily. **Mechanism of action Azithromycin binds to the 50S subunit of the 70S bacterial ribosomes, and therefore inhibits RNA-dependent protein synthesis in bacterial cells.**Half life :*68 hours"
AZOMYCIN 250mg 6 Caps.AZITHROMYCINPHARCOAntibiotic.Macrolide25.2"Description: *Azithromycin is a semi-synthetic macrolide antibiotic of the azalide class.**dose:*Adult: PO- Respiratory tract, Skin and soft tissue infections- 500 mg once daily for 3 days. Or 500mg on day 1 followed by 250mg on days 2 to 5. *Typhoid- 500 mg once daily for 7 days. *Uncomplicated gonorrhoea- 2 g single dose. *Granuloma inguinale- Initial: 1 g, then 500 mg/day until all lesions has healed completely.*Chancroid/Chlamydial urethritis: 1 g single dose Prophylaxis of disseminated MAC infections 1.2 g once weekly. Treatment or secondary prophylaxis: administered along with other antimycobacterials: 500 mg once daily. **Mechanism of action Azithromycin binds to the 50S subunit of the 70S bacterial ribosomes, and therefore inhibits RNA-dependent protein synthesis in bacterial cells.**Half life :*68 hours"
BABY COMFORT OINT. 20 GMPHARCO16Skin soothing for diaper area.
BABY REST 40mg/0.6ml oral dropsSIMETHICONEPHARCO4.3About Simethicone*Oral anti-foaming agent, Silicones, Antiflatulent.*Mechanism of Action of Simethicone*This anti-gas (anti-flatulence) medication acts in the stomach and intestines to change the surface tension of gas bubbles, enabling smaller bubbles to join together into bigger bubbles. It results elimination of gas more easily by belching or passing flatus.*Indications for Simethicone*1. Abdominal pain which is due to excessive gas in the digestive tract *2. Before gastroscopy or radiography of the bowel
BARAKA 100 MG 24 CAPS.NIGELLA SATIVA OILPHARCO5
BARAKA 450 MG 24 CAPS.NIGELLA SATIVA OILPHARCO7
BILICHOL 24 Caps.BORNEOL -- CAMPHENE -- CINEOL -- MENTHOL -- MENTHONE -- PINENE ( ALPHA & BETA )PHARCO5.9
BIPERIDEN 2mg 30 tab.BIPERIDENEPHARCOAntiparkinson Agents. Muscarinic Antagonist13.2"Description *A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.**Indication:*For use as an adjunct in the therapy of all forms of parkinsonism and control of extrapyramidal disorders secondary to neuroleptic drug therapy.**Mechanism of action Parkinsonism is thought to result from an imbalance between the excitatory (cholinergic) and inhibitory (dopaminergic) systems in the corpus striatum. The mechanism of action of centrally active anticholinergic drugs such as biperiden is considered to relate to competitive antagonism of acetylcholine at cholinergic receptors in the corpus striatum, which then restores the balance."
BISOLOCK 10mg 20 F.C.tab.BISOPROLOL FUMARATEPHARCOAnti-hypertensive.Beta blocker.Selective B111About Bisoprolol*Beta1-selective adrenergic blocker, Antihypertensive.**Mechanism of Action of Bisoprolol*Bisoprolol is a cardio selective beta-1 adrenergic antagonist.It has negative chronotropic and negative inotropic effects on heart. It decreases oxygen consumption- cardiac work and aortic pressure. It decreases central sympathetic out flow and also decreases nor adrenaline and renin releases. The drug decreases BP in hypertensive individuals. **Indications for Bisoprolol*1.Hypertension *2.Coronary artery diseases **Contra-indications of Bisoprolol*1.Hypersensitivity to the drug *2.Second or third degree heart block *3.Congestive heart failure *4.Cardiogenic shock *5.Sinus Bradycardia *6.Chronic obstructive pulmonary diseases *7.Bronchial asthma *9.Peripheral arteriolar disorders *10.Renal impairment.
BISOLOCK 2.5mg 20 F.C.tab.BISOPROLOL FUMARATEPHARCOAnti-hypertensive.Beta blocker.Selective B17.5About Bisoprolol*Beta1-selective adrenergic blocker, Antihypertensive.**Mechanism of Action of Bisoprolol*Bisoprolol is a cardio selective beta-1 adrenergic antagonist.It has negative chronotropic and negative inotropic effects on heart. It decreases oxygen consumption- cardiac work and aortic pressure. It decreases central sympathetic out flow and also decreases nor adrenaline and renin releases. The drug decreases BP in hypertensive individuals. **Indications for Bisoprolol*1.Hypertension *2.Coronary artery diseases **Contra-indications of Bisoprolol*1.Hypersensitivity to the drug *2.Second or third degree heart block *3.Congestive heart failure *4.Cardiogenic shock *5.Sinus Bradycardia *6.Chronic obstructive pulmonary diseases *7.Bronchial asthma *9.Peripheral arteriolar disorders *10.Renal impairment.
BISOLOCK 5mg 20 F.C.tab.BISOPROLOL FUMARATEPHARCOAnti-hypertensive.Beta blocker.Selective B19About Bisoprolol*Beta1-selective adrenergic blocker, Antihypertensive.**Mechanism of Action of Bisoprolol*Bisoprolol is a cardio selective beta-1 adrenergic antagonist.It has negative chronotropic and negative inotropic effects on heart. It decreases oxygen consumption- cardiac work and aortic pressure. It decreases central sympathetic out flow and also decreases nor adrenaline and renin releases. The drug decreases BP in hypertensive individuals. **Indications for Bisoprolol*1.Hypertension *2.Coronary artery diseases **Contra-indications of Bisoprolol*1.Hypersensitivity to the drug *2.Second or third degree heart block *3.Congestive heart failure *4.Cardiogenic shock *5.Sinus Bradycardia *6.Chronic obstructive pulmonary diseases *7.Bronchial asthma *9.Peripheral arteriolar disorders *10.Renal impairment.
BISOLOCK-D 5/12.5mg 20 F.C.tabBISOPROLOL FUMARATE -- HYDROCHLOROTHIAZIDEPHARCOAnti-hypertensive.Combined Beta blocker with Diuretic9Indications for Bisoprolol -- Hydrochlorothiazide*It is the combination of beta blocker Bisoprolol and diuretic Hydrochlorothiazide. *Hypertention **Typical Dosage for Bisoprolol -- Hydrochlorothiazide*1 tablet / day**Pregnancy Related Information*Contraindicated- since Hydrochlorothiazide is contraindicated in pregnancy, the combination generic cannot be used in pregnancy*Breast Feeding Related Information*Contraindicated- since Hydrochlorothiazide is contraindicated in lactation, the combination generic cannot be used in breast feeding.*
BUCCAZOLE 2% oral gelMICONAZOLEPHARCOantifungals.Imidazoles7About Miconazole*An imidazole derivative, Broad spectrum Antifungal.**Mechanism of Action of Miconazole*Miconazole is fungicidal or fungistatic depending on the drug concentrations. I t inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochromeP450 enzyme 14 alpha demethylase and impair ergosterol synthesis*Indications for Miconazole*1.Tinea versicolor *2.Vulvovaginal candidiasis *3.Tinea pedis *4.Tinea corporis *5.Tinea cruris *6.Otomycosis *7.Onychomycosis *8.Oral candidiasis *9.Intestinal candidiasis *10.Diaper dermatitis*
CALAMINE lotion 120 ML B.P 93CALAMINE -- ZINC OXIDEPHARCO5
CALCIUM PHARCO 115mg/5ml 120ml syrupCALCIUMPHARCOSupplement8.5Mechanism of Action of Calcium*Calcium is essential for maintaining the functional integrity of nervous, muscular, and skeletal system. It controls excitability of nerves and muscles and regulates permeability of cell membrane. It also regulates cell adhesion and maintains integrity of cell membrane. Calcium acts as intracellular messenger for hormones, autacoids, and transmitters. It is required for excitation-contraction coupling in all types of muscle and excitation-secretion coupling in exocrine and endocrine glands. It is essential for release of transmitters from nerve endings and other release reactions. It is also essential for impulse generation in heart and determines level of automaticity and *A-V conduction. Calcium is also required for blood-coagulation. **Indications for Calcium*1.Hypocalcaemia *2.Calcium and vitamin D deficiency *3.Calcium deficiency during pregnancy and lactation *4.Rickets *5.Prevention of osteoporosis in postmenopausal women *6.Chronic renal
CALCIUM PHARCO 950mg 20 chewable tab.CALCIUM CITRATEPHARCO4.5About Calcium Citrate Malate*Calcium citrate malate is a water-soluble calcium supplement. It is the calcium salt of citric acid and malic acid with variable composition. It is purported to be highly bioavailable.
CANDEBLOCK 16mg 20 tabs.CANDESARTAN CILEXETILPHARCOAntihypertensive.ARBs31.2About Candesartan Cilexetil*Angiotensin || Antagonist, Antihypertensive agent*Mechanism of Action of Candesartan Cilexetil*It is a antagonist of angiotensin 2 at AT-1 receptor.It decreases peripheral resistance and lowers BP in hypertensive individuals. It blocks all actions of angiotensin-2 such as 1.Vasoconstriction,2. Central and peripheral sympathetic stimulus,3. Release of aldosterone and adrenaline,4. Salt and water reabsorption ,5.Central actions like thirst,vasopressin release, and growth promoting actions on heart and blood vessals*Indications for Candesartan Cilexetil*Hypertension*Interactions for Candesartan Cilexetil*Diuretics and other antihypertensives: Increased risk of hypotension *Lithium: Increased lithium blood level *NSAID: Decreased antihypertensive effect *Potassium sparing diuretics, Potassium supplements: Increased risk of hyperkalemia
CANDEBLOCK 8mg 20 tabs.CANDESARTAN CILEXETILPHARCOAntihypertensive.ARBs20About Candesartan Cilexetil*Angiotensin || Antagonist, Antihypertensive agent*Mechanism of Action of Candesartan Cilexetil*It is a antagonist of angiotensin 2 at AT-1 receptor.It decreases peripheral resistance and lowers BP in hypertensive individuals. It blocks all actions of angiotensin-2 such as 1.Vasoconstriction,2. Central and peripheral sympathetic stimulus,3. Release of aldosterone and adrenaline,4. Salt and water reabsorption ,5.Central actions like thirst,vasopressin release, and growth promoting actions on heart and blood vessals*Indications for Candesartan Cilexetil*Hypertension*Interactions for Candesartan Cilexetil*Diuretics and other antihypertensives: Increased risk of hypotension *Lithium: Increased lithium blood level *NSAID: Decreased antihypertensive effect *Potassium sparing diuretics, Potassium supplements: Increased risk of hyperkalemia
CANDEBLOCK- D 16/12.5mg 20 tab.CANDESARTAN CILEXETIL -- HYDROCHLOROTHIAZIDEPHARCOAnti-hypertensive. combined angiotensin blocker with diuretic36About Candesartan Cilexetil*Angiotensin || Antagonist, Antihypertensive agent*Mechanism of Action of Candesartan Cilexetil*It is a antagonist of angiotensin 2 at AT-1 receptor.It decreases peripheral resistance and lowers BP in hypertensive individuals. It blocks all actions of angiotensin-2 such as 1.Vasoconstriction,2. Central and peripheral sympathetic stimulus,3. Release of aldosterone and adrenaline,4. Salt and water reabsorption ,5.Central actions like thirst,vasopressin release, and growth promoting actions on heart and blood vessals*Indications for Candesartan Cilexetil*Hypertension*Interactions for Candesartan Cilexetil*Diuretics and other antihypertensives: Increased risk of hypotension *Lithium: Increased lithium blood level *NSAID: Decreased antihypertensive effect *Potassium sparing diuretics, Potassium supplements: Increased risk of hyperkalemia
CEREBROCETAM 1gm/5ml 6 amp.PIRACETAMPHARCO14.5The way piracetam works is not fully understood. It may work by altering the availability of the brain s supply of neurochemicals (neurotransmitters, enzymes and hormones) or by improving the brain s oxygen supply.**What is it used for?*Uncontrollable twitching or jerking of the muscles, particularly in the arms and legs, caused by a problem in the brain or nervous system (myoclonus of cortical origin). This medicine is used in combination with other treatments for this condition.***
CEREBROCETAM 20gm/100ml oral soln.PIRACETAMPHARCO12The way piracetam works is not fully understood. It may work by altering the availability of the brain s supply of neurochemicals (neurotransmitters, enzymes and hormones) or by improving the brain s oxygen supply.**What is it used for?*Uncontrollable twitching or jerking of the muscles, particularly in the arms and legs, caused by a problem in the brain or nervous system (myoclonus of cortical origin). This medicine is used in combination with other treatments for this condition.***
CEREBROCETAM 400mg 30 Caps.PIRACETAMPHARCO12.75The way piracetam works is not fully understood. It may work by altering the availability of the brain s supply of neurochemicals (neurotransmitters, enzymes and hormones) or by improving the brain s oxygen supply.**What is it used for?*Uncontrollable twitching or jerking of the muscles, particularly in the arms and legs, caused by a problem in the brain or nervous system (myoclonus of cortical origin). This medicine is used in combination with other treatments for this condition.***
CEREBROCETAM 800mg 30 F.C. tabs.PIRACETAMPHARCO15The way piracetam works is not fully understood. It may work by altering the availability of the brain s supply of neurochemicals (neurotransmitters, enzymes and hormones) or by improving the brain s oxygen supply.**What is it used for?*Uncontrollable twitching or jerking of the muscles, particularly in the arms and legs, caused by a problem in the brain or nervous system (myoclonus of cortical origin). This medicine is used in combination with other treatments for this condition.***
CETRAK 10mg 10 tab.CETIRIZINEPHARCOAnti-histamine.Anti-Allergy8About Cetirizine*Second Generation H1 Antagonist, Metabolite of hydroxyzine, Antihistamine.**Mechanism of Action of Cetirizine*This drug is a selective peripheral H1 receptor antagonist. Thus it inhibits the allergic symptoms produced by histamines like cold, rhinorrhea, sneezing, urticaria etc. The drug has some mast cell stabilizing properties. It also inhibit eotaxin-induced eosinophil TEM through both dermal and lung micro vascular endothelial cells. So inhibit eosinophil chemotaxis and also inflammation caused by it.**Indications for Cetirizine*1. Sneezing *2. Rhinorrhoea *3. Postnasal discharge. *4. Common coughs *5. Colds. *6. Chronic urticaria *7. Dermatitis *8. Pruritic skin disorders *9. Hay fever *10. Angioedema
CETRAK 1mg/ml 120ml syrupCETIRIZINEPHARCOAnti-histamine.Anti-Allergy8About Cetirizine*Second Generation H1 Antagonist, Metabolite of hydroxyzine, Antihistamine.**Mechanism of Action of Cetirizine*This drug is a selective peripheral H1 receptor antagonist. Thus it inhibits the allergic symptoms produced by histamines like cold, rhinorrhea, sneezing, urticaria etc. The drug has some mast cell stabilizing properties. It also inhibit eotaxin-induced eosinophil TEM through both dermal and lung micro vascular endothelial cells. So inhibit eosinophil chemotaxis and also inflammation caused by it.**Indications for Cetirizine*1. Sneezing *2. Rhinorrhoea *3. Postnasal discharge. *4. Common coughs *5. Colds. *6. Chronic urticaria *7. Dermatitis *8. Pruritic skin disorders *9. Hay fever *10. Angioedema
CETRIMIDE 1% cream 20 GMCETRIMIDEPHARCO3.4About Cetrimide*Quaternary ammonium compound, a cationic surfactant, Antiseptic agent, a detergent ,disinfectant.*Mechanism of Action of Cetrimide*Cetrimide is a cationic surfactant. It destroys or damages the cell membrane by lowering surface tension. It causes microbial protein denaturation and produces antiseptic action.
CHOLESTRAN 4g 12 sachetsCHOLESTYRAMINEPHARCOAntihyperlipidemic.Bile acid sequestrants19.8About Cholestyramine*Bile Acid Sequestrant, chloride salt of a basic anion exchange resin, Antilipemic(cholesterol lowering agent).
CIPROFAR 250mg 10 F.C.tab.CIPROFLOXACINPHARCOAntibiotic.quinolone27About Ciprofloxacin*It is a broad spectrum fluoroquinolone with activity against Pseudomonas aeruginosa. **Indications for Ciprofloxacin*1.Urinary tract infection *2.Respiratory tract infection *3.Bone and joint infections, *4.Infectious diarrhoea *5.Gonorrhoea *6.ENT infections *7.Skin and soft tissue infections *8.Typhoid fever *9.Intra-abdominal infections *10.Prostatitis *11. Sinusitis *12.Chancroid *13.Gynaecological infections *14.Tularemia**Special Precautions while taking Ciprofloxacin*1.Hepatic impairment *2.Renal impairment *3.Epilepsy *4.Dehydration *5.Caution while driving the vehicle or operating machine or involved in any hazardous activities. **
CIPROFAR 3% eye drops 5 MLCIPROFLOXACINPHARCOAntibiotic.quinolone12About Ciprofloxacin*It is a broad spectrum fluoroquinolone with activity against Pseudomonas aeruginosa. *EYE DROPS: It is a fluroquinolone antibacterial having broad spectrum of activity.**Indications for Ciprofloxacin*1.Urinary tract infection *2.Respiratory tract infection *3.Bone and joint infections, *4.Infectious diarrhoea *5.Gonorrhoea *6.ENT infections *7.Skin and soft tissue infections *8.Typhoid fever *9.Intra-abdominal infections *10.Prostatitis *11. Sinusitis *12.Chancroid *13.Gynaecological infections *14.Tularemia**Special Precautions while taking Ciprofloxacin*1.Hepatic impairment *2.Renal impairment *3.Epilepsy *4.Dehydration *5.Caution while driving the vehicle or operating machine or involved in any hazardous activities. **
CIPROFAR 500mg 10 F.C.tab.CIPROFLOXACINPHARCOAntibiotic.quinolone36About Ciprofloxacin*It is a broad spectrum fluoroquinolone with activity against Pseudomonas aeruginosa. **Indications for Ciprofloxacin*1.Urinary tract infection *2.Respiratory tract infection *3.Bone and joint infections, *4.Infectious diarrhoea *5.Gonorrhoea *6.ENT infections *7.Skin and soft tissue infections *8.Typhoid fever *9.Intra-abdominal infections *10.Prostatitis *11. Sinusitis *12.Chancroid *13.Gynaecological infections *14.Tularemia**Special Precautions while taking Ciprofloxacin*1.Hepatic impairment *2.Renal impairment *3.Epilepsy *4.Dehydration *5.Caution while driving the vehicle or operating machine or involved in any hazardous activities. **
CIPROFAR 750mg 10 F.C.tab.CIPROFLOXACINPHARCOAntibiotic.quinolone45About Ciprofloxacin*It is a broad spectrum fluoroquinolone with activity against Pseudomonas aeruginosa. **Indications for Ciprofloxacin*1.Urinary tract infection *2.Respiratory tract infection *3.Bone and joint infections, *4.Infectious diarrhoea *5.Gonorrhoea *6.ENT infections *7.Skin and soft tissue infections *8.Typhoid fever *9.Intra-abdominal infections *10.Prostatitis *11. Sinusitis *12.Chancroid *13.Gynaecological infections *14.Tularemia**Special Precautions while taking Ciprofloxacin*1.Hepatic impairment *2.Renal impairment *3.Epilepsy *4.Dehydration *5.Caution while driving the vehicle or operating machine or involved in any hazardous activities. **
CITROLIN mouth wash and gargleCETRIMIDE -- LIDOCAINEPHARCO3.3"is used to obtain a local anaesthesia of the*lining of the inside of the mouth (buccal mucosa).*It contains two active ingredients:*ï؟½ lidocaine, a local anaesthetic, which numbs the painful*area temporarily,*ï؟½ cetrimide, an antiseptic, which kills any micro?organisms*that are present.*XYLONOR SPRAY is for children over 4 years old and adults.*Only a dentist can administer this product.*"
CITROLIN-F gargleCETRIMIDE -- CHLORHEXIDINE -- LIDOCAINE -- SODIUM FLUORIDEPHARCO3.5About Chlorhexidine*A bisbiguanide antimicrobial agent, Anti-infective, antiseptic.*Mechanism of Action of Chlorhexidine*This drug has positive charge so it attach to the negative charge cell wall. This destabilizes and destroys the integrity and penetrates bacterial cell membranes. It results precipitation of the cytoplasm and interferes with membrane function by inhibiting oxygen utilization leading to a decrease in cellular ATP levels and cell death. In gram-negative bacteria, chlorhexidine affects the outer membrane allowing the release of periplasmic enzymes. The inner membrane of these organisms is not ruptured but the uptake of small molecules is impaired. At low concentrations chlorhexidine exhibits a bacteriostatic effect while at high concentrations it is bactericidal.
CLAVIMOX 1 GM 8 F.C. TAB.AMOXICILLIN -- CLAVULANIC ACIDPHARCOPenicillins.Penicillin with B-lactamase inhbitor23.5Amoxicillin is an analog of ampicillin, derived from the basic penicillin nucleus, 6-aminopenicillanic acid*Clavulanic acid is produced by the fermentation of Streptomyces clavuligerus. It is a beta-lactam structurally related to the penicillins and possesses the ability to inactivate some beta-lactamases by blocking the active sites of these enzymes.*Lower Respiratory Tract Infections - caused by beta-lactamase-producing isolates of Haemophilus influenzae and Moraxella catarrhalis.**Acute Bacterial Otitis Media - caused by beta-lactamase-producing isolates of H. influenzae and M. catarrhalis.**Sinusitis - caused by beta-lactamase-producing isolates of H. influenzae and M. catarrhalis.**Skin and Skin Structure Infections - caused by beta-lactamase-producing isolates of Staphylococcus aureus, Escherichia coli, and Klebsiella species.**Urinary Tract Infections - caused by beta-lactamase-producing isolates of E. coli, Klebsiella species, and Enterobacter species.
CLAVIMOX 228.5mg/5ml pd. for oral 70ml susp.AMOXICILLIN -- CLAVULANIC ACIDPHARCOPenicillins.Penicillin with B-lactamase inhbitor17.25Amoxicillin is an analog of ampicillin, derived from the basic penicillin nucleus, 6-aminopenicillanic acid*Clavulanic acid is produced by the fermentation of Streptomyces clavuligerus. It is a beta-lactam structurally related to the penicillins and possesses the ability to inactivate some beta-lactamases by blocking the active sites of these enzymes.*Lower Respiratory Tract Infections - caused by beta-lactamase-producing isolates of Haemophilus influenzae and Moraxella catarrhalis.**Acute Bacterial Otitis Media - caused by beta-lactamase-producing isolates of H. influenzae and M. catarrhalis.**Sinusitis - caused by beta-lactamase-producing isolates of H. influenzae and M. catarrhalis.**Skin and Skin Structure Infections - caused by beta-lactamase-producing isolates of Staphylococcus aureus, Escherichia coli, and Klebsiella species.**Urinary Tract Infections - caused by beta-lactamase-producing isolates of E. coli, Klebsiella species, and Enterobacter species.
CLAVIMOX 312.5mg/5ml pd. for oral 60 mlAMOXICILLIN -- CLAVULANIC ACIDPHARCOPenicillins.Penicillin with B-lactamase inhbitor16.5Amoxicillin is an analog of ampicillin, derived from the basic penicillin nucleus, 6-aminopenicillanic acid*Clavulanic acid is produced by the fermentation of Streptomyces clavuligerus. It is a beta-lactam structurally related to the penicillins and possesses the ability to inactivate some beta-lactamases by blocking the active sites of these enzymes.*Lower Respiratory Tract Infections - caused by beta-lactamase-producing isolates of Haemophilus influenzae and Moraxella catarrhalis.**Acute Bacterial Otitis Media - caused by beta-lactamase-producing isolates of H. influenzae and M. catarrhalis.**Sinusitis - caused by beta-lactamase-producing isolates of H. influenzae and M. catarrhalis.**Skin and Skin Structure Infections - caused by beta-lactamase-producing isolates of Staphylococcus aureus, Escherichia coli, and Klebsiella species.**Urinary Tract Infections - caused by beta-lactamase-producing isolates of E. coli, Klebsiella species, and Enterobacter species.
CLAVIMOX 457mg/5ml pd. for oral 75 mlAMOXICILLIN -- CLAVULANIC ACIDPHARCOPenicillins.Penicillin with B-lactamase inhbitor25.25Amoxicillin is an analog of ampicillin, derived from the basic penicillin nucleus, 6-aminopenicillanic acid*Clavulanic acid is produced by the fermentation of Streptomyces clavuligerus. It is a beta-lactam structurally related to the penicillins and possesses the ability to inactivate some beta-lactamases by blocking the active sites of these enzymes.*Lower Respiratory Tract Infections - caused by beta-lactamase-producing isolates of Haemophilus influenzae and Moraxella catarrhalis.**Acute Bacterial Otitis Media - caused by beta-lactamase-producing isolates of H. influenzae and M. catarrhalis.**Sinusitis - caused by beta-lactamase-producing isolates of H. influenzae and M. catarrhalis.**Skin and Skin Structure Infections - caused by beta-lactamase-producing isolates of Staphylococcus aureus, Escherichia coli, and Klebsiella species.**Urinary Tract Infections - caused by beta-lactamase-producing isolates of E. coli, Klebsiella species, and Enterobacter species.
CLAVIMOX 625 MG 12 F.C. TAB.AMOXICILLIN -- CLAVULANIC ACIDPHARCOPenicillins.Penicillin with B-lactamase inhbitor29Amoxicillin is an analog of ampicillin, derived from the basic penicillin nucleus, 6-aminopenicillanic acid*Clavulanic acid is produced by the fermentation of Streptomyces clavuligerus. It is a beta-lactam structurally related to the penicillins and possesses the ability to inactivate some beta-lactamases by blocking the active sites of these enzymes.*Lower Respiratory Tract Infections - caused by beta-lactamase-producing isolates of Haemophilus influenzae and Moraxella catarrhalis.**Acute Bacterial Otitis Media - caused by beta-lactamase-producing isolates of H. influenzae and M. catarrhalis.**Sinusitis - caused by beta-lactamase-producing isolates of H. influenzae and M. catarrhalis.**Skin and Skin Structure Infections - caused by beta-lactamase-producing isolates of Staphylococcus aureus, Escherichia coli, and Klebsiella species.**Urinary Tract Infections - caused by beta-lactamase-producing isolates of E. coli, Klebsiella species, and Enterobacter species.
COLOMINT 24 Caps.PEPPERMINT OILPHARCO5.5Peppermint oil is derived from the peppermint plant -- a cross between water mint and spearmint -- that thrives in Europe and North America.**Peppermint oil is commonly used as flavoring in foods and beverages and as a fragrance in soaps and cosmetics. Peppermint oil also is used for a variety of health conditions and can be taken orally in dietary supplements or topically as a skin cream or ointment.*
DALIVENT 0.5 MG 10 F.C. TABS.ROFLUMILASTPHARCO20Roflumilast is a drug that acts as a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). It has anti-inflammatory effects and is used as an orally administered drug for the treatment of inflammatory conditions of the lungs such as chronic obstructive pulmonary disease (COPD).**Its primary clinical use is in the prevention of exacerbations (lung attacks) in severe COPD.
DECLOPHEN 0.1% eye dropsDICLOFENAC SODIUMPHARCONSAID.Acetic acid derivatives4.5"Description *A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt. **Indication :*For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.**Mechanism of action The antiinflammatory effects of diclofenac are believed to be due to inhibition of both leukocyte migration and the enzyme cylooxygenase (COX-1 and COX-2), leading to the peripheral inhibition of prostaglandin synthesis. As prostaglandins sensitize pain receptors, inhibition of their synthesis is responsible for the analgesic effects of diclofenac. Antipyretic effects may be due to action on the hypothalamus, resulting in peripheral dilation, increased cutaneous blood flow, and subsequent heat dissipation."
DECLOPHEN 100mg 5 supp.DICLOFENAC SODIUMPHARCONSAID.Acetic acid derivatives10.5"Description *A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt. **Indication :*For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.**Mechanism of action The antiinflammatory effects of diclofenac are believed to be due to inhibition of both leukocyte migration and the enzyme cylooxygenase (COX-1 and COX-2), leading to the peripheral inhibition of prostaglandin synthesis. As prostaglandins sensitize pain receptors, inhibition of their synthesis is responsible for the analgesic effects of diclofenac. Antipyretic effects may be due to action on the hypothalamus, resulting in peripheral dilation, increased cutaneous blood flow, and subsequent heat dissipation."
DECLOPHEN 12.5mg 5 infantile supp.DICLOFENAC SODIUMPHARCONSAID.Acetic acid derivatives6.5"Description *A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt. **Indication :*For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.**Mechanism of action The antiinflammatory effects of diclofenac are believed to be due to inhibition of both leukocyte migration and the enzyme cylooxygenase (COX-1 and COX-2), leading to the peripheral inhibition of prostaglandin synthesis. As prostaglandins sensitize pain receptors, inhibition of their synthesis is responsible for the analgesic effects of diclofenac. Antipyretic effects may be due to action on the hypothalamus, resulting in peripheral dilation, increased cutaneous blood flow, and subsequent heat dissipation."
DECLOPHEN 25mg 20 tab.DICLOFENAC SODIUMPHARCONSAID.Acetic acid derivatives9.75"Description *A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt. **Indication :*For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.**Mechanism of action The antiinflammatory effects of diclofenac are believed to be due to inhibition of both leukocyte migration and the enzyme cylooxygenase (COX-1 and COX-2), leading to the peripheral inhibition of prostaglandin synthesis. As prostaglandins sensitize pain receptors, inhibition of their synthesis is responsible for the analgesic effects of diclofenac. Antipyretic effects may be due to action on the hypothalamus, resulting in peripheral dilation, increased cutaneous blood flow, and subsequent heat dissipation."
DECLOPHEN 25mg 5 INFANTILE supp.DICLOFENAC SODIUMPHARCONSAID.Acetic acid derivatives7.5"Description *A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt. **Indication :*For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.**Mechanism of action The antiinflammatory effects of diclofenac are believed to be due to inhibition of both leukocyte migration and the enzyme cylooxygenase (COX-1 and COX-2), leading to the peripheral inhibition of prostaglandin synthesis. As prostaglandins sensitize pain receptors, inhibition of their synthesis is responsible for the analgesic effects of diclofenac. Antipyretic effects may be due to action on the hypothalamus, resulting in peripheral dilation, increased cutaneous blood flow, and subsequent heat dissipation."
DECLOPHEN 50 mg 20 tab.DICLOFENAC SODIUMPHARCONSAID.Acetic acid derivatives11.25"Description *A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt. **Indication :*For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.**Mechanism of action The antiinflammatory effects of diclofenac are believed to be due to inhibition of both leukocyte migration and the enzyme cylooxygenase (COX-1 and COX-2), leading to the peripheral inhibition of prostaglandin synthesis. As prostaglandins sensitize pain receptors, inhibition of their synthesis is responsible for the analgesic effects of diclofenac. Antipyretic effects may be due to action on the hypothalamus, resulting in peripheral dilation, increased cutaneous blood flow, and subsequent heat dissipation."
DECLOPHEN 75mg 6 ampsDICLOFENAC SODIUMPHARCONSAID.Acetic acid derivatives22.5"Description *A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt. **Indication :*For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.**Mechanism of action The antiinflammatory effects of diclofenac are believed to be due to inhibition of both leukocyte migration and the enzyme cylooxygenase (COX-1 and COX-2), leading to the peripheral inhibition of prostaglandin synthesis. As prostaglandins sensitize pain receptors, inhibition of their synthesis is responsible for the analgesic effects of diclofenac. Antipyretic effects may be due to action on the hypothalamus, resulting in peripheral dilation, increased cutaneous blood flow, and subsequent heat dissipation."
DECLOPHEN Emulgel 1% 30 GMDICLOFENAC SODIUMPHARCONSAID.Acetic acid derivatives10.5"Description *A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt. **Indication :*For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.**Mechanism of action The antiinflammatory effects of diclofenac are believed to be due to inhibition of both leukocyte migration and the enzyme cylooxygenase (COX-1 and COX-2), leading to the peripheral inhibition of prostaglandin synthesis. As prostaglandins sensitize pain receptors, inhibition of their synthesis is responsible for the analgesic effects of diclofenac. Antipyretic effects may be due to action on the hypothalamus, resulting in peripheral dilation, increased cutaneous blood flow, and subsequent heat dissipation."
DECLOPHEN FAST 50mg Gr. for Oral susp. 10 SACHETSDICLOFENAC POTASSIUMPHARCONSAID.Acetic acid derivatives18About Diclofenac Potassium*NSAID, anti-inflammatory ,antipyretic and analgesic.**Mechanism of Action of Diclofenac Potassium*Diclofenac possess analgesic, anti-inflammatory and antipyretic action. It inhibits the enzyme cyclo-oxygenase and there by inhibits the synthesis of Prostaglandins (((PGs))). It is more potent against cyclo-oxygenase-2 enzyme as compared to other NSAIDs like Indomethacin, Naproxen etc. It reduces intracellular concentrations of free arachidonic acid in leukocyte by altering its release or uptake.**Indications for Diclofenac Potassium*1.Rheumatoid arthritis *2.Ankylosing spondylitis *3.Acute gout *4.Joint disorders e.g. inflammatory disease in joints, crystal deposition in the joints *5.Osteoarthritis *6.For the relief of pain and inflammation in dental minor surgery and orthopedic *7.Dysmenorrhoea
DECLOPHEN PLUS 50/250mg 20 Caps.CHLORZOXAZONE -- DICLOFENAC POTASSIUMPHARCOskeletal muscle relaxant12About Chlorzoxazone*A benzoxazolone derivative, Centrally acting Muscle relaxant and mild sedative.*Mechanism of Action of Chlorzoxazone*This muscle relaxant works by blocking nerve impulses (or pain sensations) that are sent to your brain. It inhibits degranulation of mast cells, subsequently preventing the release of histamine and slow-reacting substance of anaphylaxis (SRS-A), mediators of type I allergic reactions. It may also reduce the release of inflammatory leukotrienes. Chlorzoxazone may act by inhibiting calcium influx.
DECLOPHEN S.R. 100mg 8 Caps.DICLOFENAC SODIUMPHARCONSAID.Acetic acid derivatives18"Description *A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt. **Indication :*For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.**Mechanism of action The antiinflammatory effects of diclofenac are believed to be due to inhibition of both leukocyte migration and the enzyme cylooxygenase (COX-1 and COX-2), leading to the peripheral inhibition of prostaglandin synthesis. As prostaglandins sensitize pain receptors, inhibition of their synthesis is responsible for the analgesic effects of diclofenac. Antipyretic effects may be due to action on the hypothalamus, resulting in peripheral dilation, increased cutaneous blood flow, and subsequent heat dissipation."
DENTOCAINE 7.5% dental gel 10 GMBENZOCAINEPHARCOAnalgesic.Local Anesthetic4About Benzocaine*Ester Local Anesthetic**Mechanism of Action of Benzocaine*It binds to sodium channel and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions. This results the blocking of depolarization of the neuronal membrane and initiation and conduction of nerve impulses at the site where it applies.**Indications for Benzocaine*1.Local anaesthetic agent *2.Topical Analgesics **Typical Dosage for Benzocaine*Topical- *Dental pain and dental procedures- *Adults and children- 20% gel or paste to area whenever necessary *Pruritic conditions- *Adult- 1%- 20% topical preparation to the affected area 3 to 4 times daily *Otitis media and other forms of otitis- *Adults- 4 to 5 drops in external auditory canal- repeat every 1 to 2 hour *Sore throat pain- *Adults and children (-3 years) - 3:1 lozenge whenever necessary *Slowly dissolved in the mouth *Male genital desensitization- *Adults- 3 to 7.5 % (water soluble base) topical prep
DENTOCALM oral oint. 5 GMBENZOCAINE -- CLOVE OILPHARCO3.5
DEPOFORT B12 1mg/ml 2 amp.HYDROXOCOBALAMINPHARCOvitamin6.75"Description *Injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency.**Mechanism of action *Vitamin B12 exists in four major forms referred to collectively as cobalamins- deoxyadenosylcobalamin, methylcobalamin, hydroxocobalamin, and cyanocobalamin. Two of these, methylcobalamin and 5-deoxyadenosyl cobalamin, are primarily used by the body. Methionine synthase needs methylcobalamin as a cofactor. This enzyme is involved in the conversion of the amino acid homocysteine into methionine. Methionine in turn is required for DNA methylation. 5-Deoxyadenosyl cobalamin is a cofactor needed by the enzyme that converts L-methylmalonyl-CoA to succinyl-CoA. This conversion is an important step in the extraction of energy from proteins and fats. Furthermore, succinyl CoA is necessary for the production of hemoglobin, the substances that carries oxygen in red blood cells."
DERMABIOTIC 10g topical powderBACITRACIN -- NEOMYCINPHARCO4.5"Mechanism of Action of Bacitracin*Bacitracin is an antibiotic produced by the strain of Bacillus subtilis. It acts by inhibiting bacterial cell wall synthesis. It is active against a variety of gram positive and a few gram negative organisms.**Mechanism of Action of Neomycin*Aminoglycosides like neomycin ""irreversibly"" bind to specific 30S-subunit proteins and 16S rRNA. Specifically neomycin binds to four nucleotides of 16S rRNA and a single amino acid of protein S12. This interferes with decoding site in the vicinity of nucleotide 1400 in 16S rRNA of 30S subunit. This region interacts with the wobble base in the anticodon of tRNA. This leads to interference with the initiation complex, misreading of mRNA so incorrect amino acids are inserted into the polypeptide leading to nonfunctional or toxic peptides and the breakup of polysomes into nonfunctional monosomes."
DERMABIOTIC 6g topical powderBACITRACIN -- NEOMYCINPHARCO4"Mechanism of Action of Bacitracin*Bacitracin is an antibiotic produced by the strain of Bacillus subtilis. It acts by inhibiting bacterial cell wall synthesis. It is active against a variety of gram positive and a few gram negative organisms.**Mechanism of Action of Neomycin*Aminoglycosides like neomycin ""irreversibly"" bind to specific 30S-subunit proteins and 16S rRNA. Specifically neomycin binds to four nucleotides of 16S rRNA and a single amino acid of protein S12. This interferes with decoding site in the vicinity of nucleotide 1400 in 16S rRNA of 30S subunit. This region interacts with the wobble base in the anticodon of tRNA. This leads to interference with the initiation complex, misreading of mRNA so incorrect amino acids are inserted into the polypeptide leading to nonfunctional or toxic peptides and the breakup of polysomes into nonfunctional monosomes."
DERMABIOTIC oint. 20 GMBACITRACIN -- NEOMYCINPHARCO5"Mechanism of Action of Bacitracin*Bacitracin is an antibiotic produced by the strain of Bacillus subtilis. It acts by inhibiting bacterial cell wall synthesis. It is active against a variety of gram positive and a few gram negative organisms.**Mechanism of Action of Neomycin*Aminoglycosides like neomycin ""irreversibly"" bind to specific 30S-subunit proteins and 16S rRNA. Specifically neomycin binds to four nucleotides of 16S rRNA and a single amino acid of protein S12. This interferes with decoding site in the vicinity of nucleotide 1400 in 16S rRNA of 30S subunit. This region interacts with the wobble base in the anticodon of tRNA. This leads to interference with the initiation complex, misreading of mRNA so incorrect amino acids are inserted into the polypeptide leading to nonfunctional or toxic peptides and the breakup of polysomes into nonfunctional monosomes."
DERMATIN 1% top. cream 14 GMCLOTRIMAZOLEPHARCOantifungals.Imidazoles4.25How does it work?*clotrimazole cream 1% contains the active ingredient clotrimazole, which is an antifungal medicine used to treat infections with fungi and yeasts.**mechanism:*Clotrimazole kills fungi and yeasts by interfering with their cell membranes. It works by stopping the fungi from producing a substance called ergosterol, which is an essential component of fungal cell membranes. The disruption in production of ergosterol causes holes to appear in the fungal cell membrane.**What is it used for?*Skin infections caused by yeasts (eg Candida), dermatophytes (eg Trichophyton, Tinea), moulds and other fungi, such as the following:*Athlete s foot (tinea pedis).*Fungal infection of the groin, ie jock itch (tinea cruris).*Ringworm (tinea corporis).*Fungal nappy rash caused by infection with Candida albicans.*Sweat rash caused by infection with Candida albicans.*Relieving the external symptoms (candidal vulvitis) of vaginal thrush (candidal vaginitis).
DERMATIN 1% TOP. POWDER 10 GMCLOTRIMAZOLEPHARCOantifungals.Imidazoles4.5How does it work?*clotrimazole, which is an antifungal medicine used to treat infections with fungi and yeasts.**mechanism:*Clotrimazole kills fungi and yeasts by interfering with their cell membranes. It works by stopping the fungi from producing a substance called ergosterol, which is an essential component of fungal cell membranes. The disruption in production of ergosterol causes holes to appear in the fungal cell membrane.**What is it used for?*Skin infections caused by yeasts (eg Candida), dermatophytes (eg Trichophyton, Tinea), moulds and other fungi, such as the following:*Athlete s foot (tinea pedis).*Fungal infection of the groin, ie jock itch (tinea cruris).*Ringworm (tinea corporis).*Fungal nappy rash caused by infection with Candida albicans.*Sweat rash caused by infection with Candida albicans.*Relieving the external symptoms (candidal vulvitis) of vaginal thrush (candidal vaginitis).
DERMATIN 1% topical soln. 20 MLCLOTRIMAZOLEPHARCOantifungals.Imidazoles3.3How does it work?*Care clotrimazole cream 1% contains the active ingredient clotrimazole, which is an antifungal medicine used to treat infections with fungi and yeasts.**mechanism:*Clotrimazole kills fungi and yeasts by interfering with their cell membranes. It works by stopping the fungi from producing a substance called ergosterol, which is an essential component of fungal cell membranes. The disruption in production of ergosterol causes holes to appear in the fungal cell membrane.**What is it used for?*Skin infections caused by yeasts (eg Candida), dermatophytes (eg Trichophyton, Tinea), moulds and other fungi, such as the following:*Athlete s foot (tinea pedis).*Fungal infection of the groin, ie jock itch (tinea cruris).*Ringworm (tinea corporis).*Fungal nappy rash caused by infection with Candida albicans.*Sweat rash caused by infection with Candida albicans.*Relieving the external symptoms (candidal vulvitis) of vaginal thrush (candidal vaginitis).
DERMATIN CORT topical cream 15 GMCLOTRIMAZOLE -- HYDROCORTISONEPHARCO5.5About Clotrimazole*A broad-spectrum antifungal antibiotic, imidazole derivative, Oral Nonabsorbed Antifungal Agent.*Mechanism of Action of Clotrimazole*Clotrimazole is fungicidal or fungistatic depending on the drug concentrations. It inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochromeP450 enzyme 14 alpha demethylase and impair ergosterol synthesis which is an essential constituent of cell membrane. Inhibition of ergosterol synthesis will alter the membrane permeability of the susceptible fungus and kill or inhibit them.
DERMOCARE cream 20 GMCETRIMIDE -- DIMETHICONEPHARCO3.5About Cetrimide*Quaternary ammonium compound, a cationic surfactant, Antiseptic agent, a detergent ,disinfectant.*Mechanism of Action of Cetrimide*Cetrimide is a cationic surfactant. It destroys or damages the cell membrane by lowering surface tension. It causes microbial protein denaturation and produces antiseptic action.
DERMOZOL 2% gel 15 GMMICONAZOLEPHARCOantifungals.Imidazoles6About Miconazole*An imidazole derivative, Broad spectrum Antifungal.**Mechanism of Action of Miconazole*Miconazole is fungicidal or fungistatic depending on the drug concentrations. I t inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochromeP450 enzyme 14 alpha demethylase and impair ergosterol synthesis*Indications for Miconazole*1.Tinea versicolor *2.Vulvovaginal candidiasis *3.Tinea pedis *4.Tinea corporis *5.Tinea cruris *6.Otomycosis *7.Onychomycosis *8.Oral candidiasis *9.Intestinal candidiasis *10.Diaper dermatitis*
DERMOZOL CORT cream 15 GMHYDROCORTISONE -- MICONAZOLEPHARCO7About Hydrocortisone*Systemic synthetic glucocorticoid, anti-inflammatory**Indications for Hydrocortisone*Intra-articular injection : *1. Rheumatoid arthritis *2. Gouty arthritis *3. Osteoarthritis *4. Joint sequelae of fractures and dislocations *5. Other inflammatory conditions of joints. *Periarticular or soft tissue injections: *1. Bursitis *2. Synovitis *3. Tendinitis *4. Taenosinovitis *5. Cystic tumors of tendon or aponeurosis *6. Epicondylitis *7. Scapulo-humeral periarthritis *8. Periarthritis of hip *9. Tarsalgias *10. Meta-tarsalgias *11. Dupuytren`s contracture *12. Peyronie`s disease.
DEXAPHEN 120ml syrupCHLORPHENIRAMINE -- DEXAMETHASONEPHARCOAnti-histamine.Anti-Allergy.Combined With glucocorticoid steroid9"DEXAMETHASONE*Description *An anti-inflammatory 9-fluoro-glucocorticoid.*Mechanism of action Dexamethasone is a glucocorticoid agonist. Unbound dexamethasone crosses cell membranes and binds with high affinity to specific cytoplasmic glucocorticoid receptors. This complex binds to DNA elements (glucocorticoid response elements) which results in a modification of transcription and, hence, protein synthesis in order to achieve inhibition of leukocyte infiltration at the site of inflammation, interference in the function of mediators of inflammatory response, suppression of humoral immune responses, and reduction in edema or scar tissue. The antiinflammatory actions of dexamethasone are thought to involve phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes."
DIABEN 5mg 20 tab.GLIBENCLAMIDE(GLYBURIDE)PHARCOAnti-Diabetic.Secretagogues.Sulfonylurea4"About Glibenclamide*Second generation sulfonylurea, Oral anti-diabetic.**Mechanism of Action of Glibenclamide*The drug exerts it`s action by increasing insulin release from the pancreas and by improving glucose tolerance. It acts on the ""sulfonylurea receptors"" on pancreatic ?-cell membrane and reduces conductance of ATP sensitive K -- channels and thus causes depolarization. This enhances Ca2 -- influx and degranultion and thus increases insulin secretion rate at any glucose concentration. It primarily increases 2nd phase insulin secretion and has little effect on 1st phase. It also slows hepatic degradation of insulin and minor action of reducing glucagon release and increasing Somatostatin release. It also exerts extrapancreatic action- by sensitizing the target tissues such as liver to insulin action. It increases the number of insulin receptors and through a post receptor action improving translation of receptor activation."
DIGESTIN 120ml syrupPAPAIN -- PEPSIN -- SANZYME 3500PHARCO7.5About Pepsin*A digestive protease, A digestive aid.*Indications for Pepsin*1.Improve blood circulation *2.Prevent abnormal blood clotting. *3.Reduce pain and inflammation associated with Phlebitis. *4.Alleviate the pain, inflammation, and discomfort of varicose veins. *5.Minimize muscle pain that occurs after exercise. *6.Minimize the inflammation and pain associated with Osteoarthritis and Rheumatoid Arthritis. *7.Alleviate the symptoms of Sinusitis. *8.Alleviate oedema.*Papain*About Papain*A fruit-derived cysteine protease enzyme present in papaya, Dietary supplement, a digestive aid.*Indications for Papain*1.Improve blood circulation *2.Prevent abnormal blood clotting. *3.Reduce pain and inflammation associated with Phlebitis. *4.Alleviate the pain, inflammation, and discomfort of varicose veins. *5.Minimize muscle pain that occurs after exercise. *6.Minimize the inflammation and pain associated with Osteoarthritis and Rheumatoid Arthritis. *7.Alleviate the symp
DIGESTIN 20 tab.PAPAIN -- SANZYME 3500PHARCO12About Papain*A fruit-derived cysteine protease enzyme present in papaya, Dietary supplement, a digestive aid.*Indications for Papain*1.Improve blood circulation *2.Prevent abnormal blood clotting. *3.Reduce pain and inflammation associated with Phlebitis. *4.Alleviate the pain, inflammation, and discomfort of varicose veins. *5.Minimize muscle pain that occurs after exercise.
DORZOLAMIDE 2% eye dropDORZOLAMIDEPHARCO30About Dorzolamide*Carbonic anhydrase inhibitor, Thiophene derivative, a sulfonamide, Antiglucoma.**Mechanism of Action of Dorzolamide*Dorzolamide is a sulfonamide used as topical carbonic anhydrase inhibitor. Inhibition of carbonic anhydrase-2 in ciliary processes of eye leads to reducing intra ocular tension by decreasing aqueous humor secretion by slowing the formation of bicarbonate ions with subsequent decrease in sodium and fluid transport.**Indications for Dorzolamide*1. Ocular hypertension *2. Open angle glaucoma **Interactions for Dorzolamide*Similar to diuretics (carbonic anhydrase inhibitor) ? as possibility of systemic absorption after topical administration.
DORZOLAMOL eye drops 5 MLDORZOLAMIDE -- TIMOLOLPHARCO30About Dorzolamide*Carbonic anhydrase inhibitor, Thiophene derivative, a sulfonamide, Antiglucoma.*Mechanism of Action of Dorzolamide*Dorzolamide is a sulfonamide used as topical carbonic anhydrase inhibitor. Inhibition of carbonic anhydrase-2 in ciliary processes of eye leads to reducing intra ocular tension by decreasing aqueous humor secretion by slowing the formation of bicarbonate ions with subsequent decrease in sodium and fluid transport.*About Timolol*Nonselective Beta Adrenergic,Blocker,Ophthalmic- Antiglaucoma,antimigraine.*Mechanism of Action of Timolol*Timolol is a non selective beta blocker. It inhibits the beta receptors (?2) present in the eye such as in the ciliary body epithelium and blood vessels. This will leads to decreased aqueous production and reduced intraocular pressure. Aqueous humor production is activated by ? receptor mediated cyclic AMP phosphokinase pathway. Beta receptor blockers will decreases the intracellular cyclic AMP level and reduces intraoc
DUVADILAN 20mg 30 tab.ISOXSUPRINEPHARCOUtirine Relaxation9.5About Isoxsuprine*A beta-adrenergic agonist, Tocolytic agent,Peripheral vasodilator.*Mechanism of Action of Isoxsuprine*The drug exerts vasodilatory and smooth muscle relaxant action through acting as a beta adrenergic receptor agonist. It relaxes veins and arteries and causes dilatation and thus improves blood flow through them. It causes uterine relaxation due to it`s direct smooth muscle relaxant action.*Indications for Isoxsuprine*1. Cerebral and peripheral vascular diseases *2. Prevention of premature labour and threatened abortion. *Typical Dosage for Isoxsuprine*Cerebral and peripheral vascular diseases: *Oral: *Starts with 20mg- 6th hourly. Reduces the dosage up to 10mg 8th hourly based on patient`s response. *I.V.: Initially at an infusion rate of 0.3mg/minute. Then adjust the dosage based on the patient`s response. *I.M.: Initially 5mg 8th hourly and gradually increases to 10 to 20mg 8th hourly. *
DYSENTERIN COMPOUND 6 sachetsDIIODOHYDROXYQUINOLINE -- KAOLIN -- NICOTINAMIDE -- PECTIN -- STREPTOMYCIN -- SUCCINYLSULPHATHIAZOLE -- SULPHADIAZINEPHARCO3.5Diiodohydroxyquinoline is used in the treatment of:*Blastocystis Infections*Cystinuria*Dysentery, Amebic**Do not take Diiodohydroxyquinoline if you have:*Drug Hypersensitivity*Liver Diseases*Optic Neuropathy, Ischemic****
ECODERM 1% topical lotion 20 MLECONAZOLEPHARCOantifungals.Imidazoles5.5About Econazole*Synthetic Imidazole derivative, Antifungal.*Mechanism of Action of Econazole**Econazole exerts its effects by altering cellular membrane and interfering with cellular enzymes.It is active against many fungi, dermatophytes and yeasts as well as some gram positive bacteria.**Indications for Econazole*1.Cutaneous candidiasis *2.Tinea pedis *3.Tinea cruris *4.Tinea versicolor **Typical Dosage for Econazole*Cutaneous candidiasis: Gently rub sufficient quantity to the affected area 2 times daily. *Tinea infection:Gently rub in to the affected area once daily.
ERYTHROMYCIN PHARCO 200mg/5ml 60ml susp.ERYTHROMYCINPHARCOAntibiotic.Macrolide7.5About Erythromycin*Macrolide Antibiotic.**Mechanism of Action of Erythromycin*Erythromycin is a member of macrolide antibiotics. It binds to the 50S sub unit of bacterial ribosome and inhibits translocation.ie: they interfere with the transfer of the newly formed peptide chain from the A site to the P site and fails to expose the A site .So that A site is unable to bind with the next aminoacyl t RNA complex. This leads to premature termination of amino acid chain and there by inhibits protein synthesis.**Indications for Erythromycin*1.Tonsilitis *2.Pharyngitis *3.Pneumonia *4.Diphtheria *5.Pertusis *6.Tetanus *7.SABE *8.Syphilis *9.Gonorrhea *10.Wound and burn infection *11.Rheumatic fever *12.Acne *13.Urogenital infection *14.Chancroid *15.Intestinal amoebiasis *16.Skin and soft tissue infections *17.Urethritis
ETODINE 300mg 10 Caps.ETODOLACPHARCONSAID.Acetic acid derivatives14.4About Etodolac*A member of pyranocarboxylic acid group of NSAID, Analgesic, Anti-inflammatory.**Mechanism of Action of Etodolac*Etodolac is an acetic acid derivative. Etodolac produces its analgesics and anti-inflammatory actions by inhibiting Prostaglandin synthesis. It has also some COX2 selective action. So its anti-inflammatory action and the frequency of gastric irritation is less as compared to other NSAIDs.**Indications for Etodolac*1. Osteoarthritis *2. Rheumatoid arthritis *3..Pain **Typical Dosage for Etodolac*Adult: 600mg - 1000mg / day in 2 - 3 divided doses. *Pain: 200 - 400 mg 3 - 4 times daily. Maximum 1g
EYE CLEAR 0.05% ophthalmic drops 15 MLTETRAHYDROZOLINEPHARCO6Tetrahydrozoline is a decongestant used to relieve redness in the eyes caused by minor eye irritations (e.g., smog, swimming, dust, or smoke). It belongs to a class of drugs known as sympathomimetic amines. It works by temporarily narrowing the blood vessels in the eye.*Some brands of tetrahydrozoline eye drops may contain lubricants. Lubricants help protect the eyes from more irritation and dryness.
FARCOBRASONE OPHTH. SUSP. 5 MLDEXAMETHASONE -- TOBRAMYCINPHARCO7.5About Dexamethasone*A potent synthetic glucocorticoid, Antiasthmatic, anti-inflammatory and immunosuppressant.*Mechanism of Action of Dexamethasone*The drug exerts it`s pharmacological action by penetrating and binding to cytoplasmic receptor protein and causes a structural change in steroid receptor complex. This structural change allows it`s migration in to the nucleus and then binding to specific sites on the DNA which leads to transcription of specific m-RNA and which ultimately regulates protein synthesis. It exerts highly selective glucocorticoid action. It stimulates the enzymes needed to decrease the inflammatory response. *The drug exerts anti-inflammatory and immunosuppressant actions as follows: - 1) Induce lipocortins in macrophages, endothelium, and fibroblasts which inhibits phospholipase A2 and thus decreases the production of Prostaglandins, leukotriens (LT), and platelet activating factor, 2) Causes negative regulation of genes for cytokines in macrophages, endothe
FARCO-CAINE 10% spray. 50 MLLIDOCAINEPHARCOAnalgesic.Local Anesthetic18"Indication *For production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks.**Mechanism of action *Lidocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses thereby effecting local anesthetic action. Lidocaine alters signal conduction in neurons by blocking the fast voltage gated sodium (Na -- ) channels in the neuronal cell membrane that are responsible for signal propagation. With sufficient blockage the membrane of the postsynaptic neuron will not depolarize and will thus fail to transmit an action potential. This creates the anaesthetic effect by not merely preventing pain signals from propagating to the brain but by aborting their birth in the first place."
FARCO-CAINE 5% oint. 20 GMLIDOCAINEPHARCOAnalgesic.Local Anesthetic4.25"Indication *For production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks.**Mechanism of action *Lidocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses thereby effecting local anesthetic action. Lidocaine alters signal conduction in neurons by blocking the fast voltage gated sodium (Na -- ) channels in the neuronal cell membrane that are responsible for signal propagation. With sufficient blockage the membrane of the postsynaptic neuron will not depolarize and will thus fail to transmit an action potential. This creates the anaesthetic effect by not merely preventing pain signals from propagating to the brain but by aborting their birth in the first place."
FARCOCIN 0.1% 15gram creamGENTAMICINPHARCO4.6About Gentamicin*Aminoglycoside antibiotic.**Mechanism of Action of Gentamicin*Gentamicin exerts its bactericidal action against gram negative organisms & some of gram positive organisms by inhibiting bacterial protein synthesis. The process involves 1. Penetration of bacterial cell membrane & binding directly to the bacterial ribosome, 2. Misleading of m-RNA codon by bacterial ribosome, 3. Formation of peptide chains with wrong amino acid sequence which gets incorporated into bacterial cell membrane and alters its permeability, 4. Bacterial cell lysis. Some bacterial strains resistant to other amino glycosides are sensitive to Gentamicin.**Indications for Gentamicin*1. Infections caused by staphylococci, pseudomonas, proteous, klebsiella, enterobacter & serratia. *2. Meningitis. *3. Endocarditis *4. Urinary Tract Infections. *5. Otitis & Ocular infections. *6. Infections of burns & Skin ulcers
FARCOCIN 0.1% 20gram creamGENTAMICINPHARCO4.75About Gentamicin*Aminoglycoside antibiotic.**Mechanism of Action of Gentamicin*Gentamicin exerts its bactericidal action against gram negative organisms & some of gram positive organisms by inhibiting bacterial protein synthesis. The process involves 1. Penetration of bacterial cell membrane & binding directly to the bacterial ribosome, 2. Misleading of m-RNA codon by bacterial ribosome, 3. Formation of peptide chains with wrong amino acid sequence which gets incorporated into bacterial cell membrane and alters its permeability, 4. Bacterial cell lysis. Some bacterial strains resistant to other amino glycosides are sensitive to Gentamicin.**Indications for Gentamicin*1. Infections caused by staphylococci, pseudomonas, proteous, klebsiella, enterobacter & serratia. *2. Meningitis. *3. Endocarditis *4. Urinary Tract Infections. *5. Otitis & Ocular infections. *6. Infections of burns & Skin ulcers
FARCOCIN 0.1% oint. 20 GMGENTAMICINPHARCO4.6About Gentamicin*Aminoglycoside antibiotic.**Mechanism of Action of Gentamicin*Gentamicin exerts its bactericidal action against gram negative organisms & some of gram positive organisms by inhibiting bacterial protein synthesis. The process involves 1. Penetration of bacterial cell membrane & binding directly to the bacterial ribosome, 2. Misleading of m-RNA codon by bacterial ribosome, 3. Formation of peptide chains with wrong amino acid sequence which gets incorporated into bacterial cell membrane and alters its permeability, 4. Bacterial cell lysis. Some bacterial strains resistant to other amino glycosides are sensitive to Gentamicin.**Indications for Gentamicin*1. Infections caused by staphylococci, pseudomonas, proteous, klebsiella, enterobacter & serratia. *2. Meningitis. *3. Endocarditis *4. Urinary Tract Infections. *5. Otitis & Ocular infections. *6. Infections of burns & Skin ulcers
FARCOCROM 4% eye drops 10 MLSODIUM CROMOGLYCATEPHARCOAnti-histamine.Anti-Allergy8About Sodium Cromoglycate*Synthetic chromone derivative, Mast Cell Stabilizer, Antiallergic, asthma prophylactic.*Mechanism of Action of Sodium Cromoglycate*This synthetic chromone derivative has several mechanism of action 1. It is a mast cell stabilizer 2. It inhibit chloride channels and inhibit the exaggerated neuronal reflexes triggered by stimulation of irritant receptors on sensory nerve endings (e.g. exercise-induced asthma) and release of preformed cytokines from several type of inflammatory cells (T-cell, Eosinophil) in allergen-induced asthma.3. It inhibit calcium influx of the cell 4.It inhibit the enzyme phosphodiesterase 5. It reduce alpha-adrenoreceptor density 6. It inhibit Ig-E dependant secretion of cells other than mast cells.
FARCODARONE 200mg 30 tab.AMIODARONEPHARCOAntiarrhythmias.Class III21"Description *An antianginal and antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting Na,K-activated myocardial adenosine triphosphatase. There is a resulting decrease in heart rate and in vascular resistance.**Indication :*Intravenously, for initiation of treatment and prophylaxis of frequently recurring ventricular fibrillation and hemodynamically unstable ventricular tachycardia in patients refractory to other therapy. Orally, for the treatment of life-threatening recurrent ventricular arrhythmias such as recurrent ventricular fibrillation and recurrent hemodynamically unstable ventricular tachycardia.**Contra-indications :*1.Hypersensitivity to the drug *2.2nd or third degree heart block *3.Congestive Heart failure *4.Cardiogenic shock *5.Severe bradycardia *6.Severe obstructive pulmonary diseases *7.Electrolyte imbalance *8.Severe Hypotension *9.Myasthenia gravis *10.Sinus node dysfunction *11.Atrial conduction defect"
FARCODARONE CONCENTRATE 50mg/ml 5 amp.AMIODARONEPHARCOAntiarrhythmias.Class III21.6"Description *An antianginal and antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting Na,K-activated myocardial adenosine triphosphatase. There is a resulting decrease in heart rate and in vascular resistance.**Indication :*Intravenously, for initiation of treatment and prophylaxis of frequently recurring ventricular fibrillation and hemodynamically unstable ventricular tachycardia in patients refractory to other therapy. Orally, for the treatment of life-threatening recurrent ventricular arrhythmias such as recurrent ventricular fibrillation and recurrent hemodynamically unstable ventricular tachycardia.**Contra-indications :*1.Hypersensitivity to the drug *2.2nd or third degree heart block *3.Congestive Heart failure *4.Cardiogenic shock *5.Severe bradycardia *6.Severe obstructive pulmonary diseases *7.Electrolyte imbalance *8.Severe Hypotension *9.Myasthenia gravis *10.Sinus node dysfunction *11.Atrial conduction defect"
FARCODOXIN 100mg 10 Caps.DOXYCYCLINEPHARCO11About Doxycycline*Tetracycline Derivative, Antibiotic.**Mechanism of Action of Doxycycline*Doxycycline is a broad spectrum antibiotic which acts against both gram positive and gram negative organisms. It exerts its bacteriostatic action by accumulating inside the bacteria through specific transporter protein and by passive diffusion & inhibits bacterial protein synthesis by attaching to 30 S subunit of bacterial ribosome (which are absent in mammals).Doxycycline interfering the attachment of aminoacyl-tRNA to the mRNA-ribosome complex and peptide chain fails to grow. It chelates cations like Ca &Mg and inhibits functioning of various enzymes & ribosome. **Indications for Doxycycline*1. Syphilis *2. Lympho granuloma veneram *3. Typhus fever *4. Respiratory tract infections *5. Prophylaxis of malaria *6. Urinogenital tract infections *7. Trachoma *8. Pelvic inflammatory disease*9. Acne *10. Diarrhoea *11. Gonorrhea in penicillin allergic individuals *12. Pneumonia *
FARCOLAC 667gm/l 120ml syrupLACTULOSEPHARCOLaxative7.5About Lactulose*A synthetic Disaccharide, Osmotic Laxative, Ammonium Detoxicant.*Mechanism of Action of Lactulose*Laxative: Lactulose is a synthetic disaccharide of galactose and fructose that resist intestinal disaccharidase activity. The sugars are joined by a beta glycosidic linkage and are resistant to hydrolysis by human digestive enzymes. Lactulose is fermented by a limited number of colonic bacteria. This can lead to changes in the colonic ecosystem in favor of some bacteria, such as lactobacilli and bifidobacteria, which may confer some health benefits. The products of fermentation include lactic acid and small-chain fatty acids. Degradation to short chain fatty acids also increases the osmotic pressure in the intestinal lumen. It also cause an increase in fecal volume due to intraluminal water retention and stimulate colonic propulsive motility result in increased fecal bulk and stimulation of peristalsis. *
FARCOLIN 120ml syrupAMMONIUM CHLORIDE -- SALBUTAMOLPHARCO6.75About Ammonium chloride*Ammonium compound, Acidifier,Expectorant.
FARCOLIN 2mg 20 tab.SALBUTAMOLPHARCO5.25About Salbutamol*Beta2-Adrenergic Agonist, Phenethylamine derivative, Bronchodilator(Antiasthma), uterine relaxant.*Mechanism of Action of Salbutamol*Salbutamol is a short acting ?2 receptor agonist. It selectively stimulates ?2 receptors present in airway, Uterus, and Vascular Smooth muscles. It directly relaxes the airway smooth muscles and produces bronchodilation. Stimulation of ?2 receptors activates Gs adenylyl-cyclase -cyclic AMP path way and produces reduction in smooth muscle tone. ?2 receptor agonists also increases the conductance of large Ca2 -- sensitive K -- channels in airway smooth muscles and leads to membrane hyperpolarisation and relaxation of smooth muscles. *?2 receptor agonists also suppress the release of Leukotrienes and histamine from the mast cells in the lung tissue and enhance mucociliary function and decrease micro vascular permeability and also inhibits Phospholipase A2 which produces inhibition of prostaglandins production.
FARCOLIN RESPIRATOR 0.5% soln. 20 MLSALBUTAMOLPHARCO18About Salbutamol*Beta2-Adrenergic Agonist, Phenethylamine derivative, Bronchodilator(Antiasthma), uterine relaxant.*Mechanism of Action of Salbutamol*Salbutamol is a short acting BETA 2 receptor agonist. It selectively stimulates BETA 2 receptors present in airway, Uterus, and Vascular Smooth muscles. It directly relaxes the airway smooth muscles and produces bronchodilation. Stimulation of BETA 2 receptors activates Gs adenylyl-cyclase -cyclic AMP path way and produces reduction in smooth muscle tone. BETA 2 receptor agonists also increases the conductance of large Ca2 -- sensitive K -- channels in airway smooth muscles and leads to membrane hyperpolarisation and relaxation of smooth muscles. *BETA 2 receptor agonists also suppress the release of Leukotrienes and histamine from the mast cells in the lung tissue and enhance mucociliary function and decrease micro vascular permeability and also inhibits Phospholipase A2 which produces inhibition of prostaglandins production.
FARCOMETHACIN 1% topical gel 20 GMINDOMETHACINPHARCONSAID.Acetic acid derivatives5.5About Indomethacin*NSAID, Indole derivative, Anti-inflammatory, potent antipyretic and analgesic.**Mechanism of Action of Indomethacin*Indomethacin acts by inhibition of Prostaglandin (PGs) synthesis and their release at the site of injury. Prostaglandins cause tenderness and amplify the action of other algesics. Indomethacin does not affect the tenderness induced by PGs but block the pain producing mechanism induced by inflammatory mediators by inhibiting the enzyme cyclo-oxygenase. **Interactions for Indomethacin*Anticoagulants: May prolong prothrombin time. Instruct patients to watch for signs & symptoms of bleeding. *Beta-Blockers: Antihypertensive effect may be blunted. *Cyclosporine: Nephrotoxicity of both agents may be increased. *Digoxin: Serum digoxin levels may be increased by ibuprofen and indomethacin. *Hydantoins: Serum hydantoin levels increased resulting in increased pharmacological and toxic effects. *Lithium: Serum lithium levels may be increased. *
FARCONCIL 1gm vialAMOXICILLINPHARCOPenicillins.Monocomponent8(Indications):* is a penicillin-like , beta-lactam antibiotic. It is used to treat bacterial infections caused by susceptible microorganisms. It prevents the bacterial growth and is used in the treatment of a number of infections such as pneumonia, bronchitis, gonorrhea, and infections of the ears, nose, throat, urinary tract, and skin. * *(Dosage):*Adult : 250 mg to 500 mg 3 times/day*Child : The recommended dose is 25 mg/kg/day in divided doses every 12 hours. ***
FARCONCIL 250mg vialAMOXICILLINPHARCOPenicillins.Monocomponent5.5(Indications):* is a penicillin-like , beta-lactam antibiotic. It is used to treat bacterial infections caused by susceptible microorganisms. It prevents the bacterial growth and is used in the treatment of a number of infections such as pneumonia, bronchitis, gonorrhea, and infections of the ears, nose, throat, urinary tract, and skin. * *(Dosage):*Adult : 250 mg to 500 mg 3 times/day*Child : The recommended dose is 25 mg/kg/day in divided doses every 12 hours. ***
FARCONCIL 500mg vialAMOXICILLINPHARCOPenicillins.Monocomponent6.5(Indications):* is a penicillin-like , beta-lactam antibiotic. It is used to treat bacterial infections caused by susceptible microorganisms. It prevents the bacterial growth and is used in the treatment of a number of infections such as pneumonia, bronchitis, gonorrhea, and infections of the ears, nose, throat, urinary tract, and skin. * *(Dosage):*Adult : 250 mg to 500 mg 3 times/day*Child : The recommended dose is 25 mg/kg/day in divided doses every 12 hours. ***
FARCOPHYLLINE 125mg 5 paed.supp.PIPERAZINE THEOPHYLLINE ETHANOATEPHARCO2.7About Piperazine*A GABA receptor agonist, Anthelmintic -Antinematodal.*Mechanism of Action of Piperazine*The drug exerts its action by acting as a GABA agonist and causing hyperpolarisation of worm muscle and relaxation and depresses the contractile action of acetyl choline resulting in flaccid paralysis of worms, which are then expelled by peristaltic movements*Indications for Piperazine*1. Ascariasis *2. Enterobiasis
FARCOPRIL 25mg 20 tab.CAPTOPRILPHARCOAnti-hypertensive.ACE4.25About Captopril*A specific competitive Angiotensin-Converting Enzyme (ACE) Inhibitor, Antihypertensive.*Mechanism of Action of Captopril*It is an angiotensin converting enzyme inhibitor prevents the conversion of angiotensin-1 to angiotensin-2 and abolishes the pressor actions of angiotensin. It decreases aldosterone secretion, sodium and water retention, and total peripheral resistance, leads to fall in BP. The arterioles dilate and the compliance of larger arteries is increased. Both systolic and diastolic BP is lowered. It has no effect on cardiac output and cardiovascular reflexes. And there is little dilatation of capacitance vessels- so postural hypotension is not a problem. The drug does not compromise renal, cerebral, and coronary blood flow. BP lowering depending up on sodium status and renin angiotensin activity. So greater fall in BP occurs in Reno vascular accelerated and malignant hypertension. The drug also increases plasma kinin levels and potentiate the hypotensive a
FARCOPRIL 50mg 20 tab.CAPTOPRILPHARCOAnti-hypertensive.ACE11About Captopril*A specific competitive Angiotensin-Converting Enzyme (ACE) Inhibitor, Antihypertensive.*Mechanism of Action of Captopril*It is an angiotensin converting enzyme inhibitor prevents the conversion of angiotensin-1 to angiotensin-2 and abolishes the pressor actions of angiotensin. It decreases aldosterone secretion, sodium and water retention, and total peripheral resistance, leads to fall in BP. The arterioles dilate and the compliance of larger arteries is increased. Both systolic and diastolic BP is lowered. It has no effect on cardiac output and cardiovascular reflexes. And there is little dilatation of capacitance vessels- so postural hypotension is not a problem. The drug does not compromise renal, cerebral, and coronary blood flow. BP lowering depending up on sodium status and renin angiotensin activity. So greater fall in BP occurs in Reno vascular accelerated and malignant hypertension. The drug also increases plasma kinin levels and potentiate the hypotensive a
FARCOPRIL PLUS 25/50mg 20 tab.CAPTOPRIL -- HYDROCHLOROTHIAZIDEPHARCOAnti-hypertensive.Combined ACE with diuretic15.6About Captopril*A specific competitive Angiotensin-Converting Enzyme (ACE) Inhibitor, Antihypertensive.*About Hydrochlorothiazide*Thiazide derivatibve, Diuretic.*Mechanism of Action of Hydrochlorothiazide*It is thiazide diuretic which exerts its action by acting at site-3(central dilating segment of early distal tubule). It binds to Na -- Cl- symporter and inhibits Na -- Cl- symport at the luminal membrane. It has additional carbonic anhydrase inhibitory actions in proximal tubules. It increases natriuresis, kaliuresis and diuresis. It decreases Ca2 -- excretion and increases Mg2 -- excretion. It also has minor carbonic anhydrase inhibitory action. It also causes direct arteriolar vasodilatation and decreases total peripheral resistance. The antihypertensive actions of the drug may be attributable to depletion of sodium and subsequent reduction in plasma volume and a decrease in peripheral resistance. Decrease in peripheral resistance is due to either the loss of sodium from the arteriolar w
FARCORELAXIN 100mg/100ml 120ml syrup.HYOSCIN-N-BUTYLBROMIDPHARCOAnti-Muscarinic.antispasmodic4.5About Hyoscine Butyl Bromide*Anti-cholinergic, a tropane alkaloid, Antispasmodic in GI and GU spasm.*Mechanism of Action of Hyoscine Butyl Bromide**Hyoscine butyl bromide is an anticholinergic drug. It exerts its action by inhibiting muscarinic (cholinergic) receptors on smooth muscles and prevents the effect of Acetylcholine. Inhibition of Acetylcholine produces relaxation of smooth muscles of gastrointestinal tract and genitourinary tract and reduces the painful spasm and cramp. *It does not produce CNS effect. *Antivertigo: Hyoscine suppresses the end organ receptors or inhibit central cholinergic pathway in vestibular nuclei. *General anaesthesia: Once muscle paralysis is no longer desired, acetyl cholinesterase inhibitors are combined with a muscarinic receptor antagonist such as Glycopyrrolate or Hyoscine or Atropine to offset the muscarinic activation resulting from esterase inhibition
FARCORELAXIN 10mg 5 adult supp.HYOSCIN-N-BUTYLBROMIDPHARCOAnti-Muscarinic.antispasmodic5About Hyoscine Butyl Bromide*Anti-cholinergic, a tropane alkaloid, Antispasmodic in GI and GU spasm.*Mechanism of Action of Hyoscine Butyl Bromide**Hyoscine butyl bromide is an anticholinergic drug. It exerts its action by inhibiting muscarinic (cholinergic) receptors on smooth muscles and prevents the effect of Acetylcholine. Inhibition of Acetylcholine produces relaxation of smooth muscles of gastrointestinal tract and genitourinary tract and reduces the painful spasm and cramp. *It does not produce CNS effect. *Antivertigo: Hyoscine suppresses the end organ receptors or inhibit central cholinergic pathway in vestibular nuclei. *General anaesthesia: Once muscle paralysis is no longer desired, acetyl cholinesterase inhibitors are combined with a muscarinic receptor antagonist such as Glycopyrrolate or Hyoscine or Atropine to offset the muscarinic activation resulting from esterase inhibition
FARCORELAXIN 20mg I.V./I.M. 3 amp.HYOSCIN-N-BUTYLBROMIDPHARCOAnti-Muscarinic.antispasmodic9About Hyoscine Butyl Bromide*Anti-cholinergic, a tropane alkaloid, Antispasmodic in GI and GU spasm.*Mechanism of Action of Hyoscine Butyl Bromide**Hyoscine butyl bromide is an anticholinergic drug. It exerts its action by inhibiting muscarinic (cholinergic) receptors on smooth muscles and prevents the effect of Acetylcholine. Inhibition of Acetylcholine produces relaxation of smooth muscles of gastrointestinal tract and genitourinary tract and reduces the painful spasm and cramp. *It does not produce CNS effect. *Antivertigo: Hyoscine suppresses the end organ receptors or inhibit central cholinergic pathway in vestibular nuclei. *General anaesthesia: Once muscle paralysis is no longer desired, acetyl cholinesterase inhibitors are combined with a muscarinic receptor antagonist such as Glycopyrrolate or Hyoscine or Atropine to offset the muscarinic activation resulting from esterase inhibition
FARCORELAXIN 7.5mg 5 INFANTILE supp.HYOSCIN-N-BUTYLBROMIDPHARCOAnti-Muscarinic.antispasmodic4.5About Hyoscine Butyl Bromide*Anti-cholinergic, a tropane alkaloid, Antispasmodic in GI and GU spasm.*Mechanism of Action of Hyoscine Butyl Bromide**Hyoscine butyl bromide is an anticholinergic drug. It exerts its action by inhibiting muscarinic (cholinergic) receptors on smooth muscles and prevents the effect of Acetylcholine. Inhibition of Acetylcholine produces relaxation of smooth muscles of gastrointestinal tract and genitourinary tract and reduces the painful spasm and cramp. *It does not produce CNS effect. *Antivertigo: Hyoscine suppresses the end organ receptors or inhibit central cholinergic pathway in vestibular nuclei. *General anaesthesia: Once muscle paralysis is no longer desired, acetyl cholinesterase inhibitors are combined with a muscarinic receptor antagonist such as Glycopyrrolate or Hyoscine or Atropine to offset the muscarinic activation resulting from esterase inhibition
FARCOSOLVIN 120ml syrupAMBROXOL -- GUAIFENESIN -- THEOPHYLLINEPHARCO7.5"(Indications) : *This medication is a mucolytic agent, prescribed for various respiratory diseases such as emphysema with bronchitis pneumoconiosis, chronic inflammatory pulmonary conditions, tracheobronchitis (respiratory tract inflammation), bronchiectasis, bronchitis with bronchospasm asthma. *Theophylline and guaifenesin combination is used to treat or prevent the symptoms of asthma or to treat chronic bronchitis and emphysema. This medicine relieves cough, wheezing, shortness of breath, and troubled breathing. It works by opening up the bronchial tubes (air passages) of the lungs and increasing the flow of air through them. ***"
FARCOSOLVIN 24 Caps.AMBROXOL -- GUAIFENESIN -- THEOPHYLLINEPHARCO11.25"(Indications) : *This medication is a mucolytic agent, prescribed for various respiratory diseases such as emphysema with bronchitis pneumoconiosis, chronic inflammatory pulmonary conditions, tracheobronchitis (respiratory tract inflammation), bronchiectasis, bronchitis with bronchospasm asthma. *Theophylline and guaifenesin combination is used to treat or prevent the symptoms of asthma or to treat chronic bronchitis and emphysema. This medicine relieves cough, wheezing, shortness of breath, and troubled breathing. It works by opening up the bronchial tubes (air passages) of the lungs and increasing the flow of air through them. ***"
FARCOTILIUM 10 MG 10 EFF. SACHETSDOMPERIDONEPHARCO5About Domperidone*Antidopaminergic, Motility stimulant,Piperidine derivative, Antiemetic, anti-vertigo.*Mechanism of Action of Domperidone*Domperidone is a potent dopamine receptor antagonist. It acts centrally and blocks the Dopamine receptor in the Chemoreceptor trigger zone and produces Antiemetic effect. *Domperidone acts peripherally in the gastrointestinal system and increases oesophageal peristalsis, oesophageal sphincter pressure and gastric motility. These all facilitates gastric emptying. Domperidone is used in migraine to relieve nausea and vomiting. *Anaesthetic adjuncts: It is used preoperatively in order to reduce the post operative vomiting. **Indications for Domperidone*1.Nausea and vomiting associated with gastrointestinal disorder and migraine. *2.Delayed gastric emptying of functional origin *3.As an Antiemetic in patient receiving cytotoxic drugs *4.Preanaesthetic medication
FARCOTILIUM 100mg/100ml 120ml susp.DOMPERIDONEPHARCO6.25About Domperidone*Antidopaminergic, Motility stimulant,Piperidine derivative, Antiemetic, anti-vertigo.*Mechanism of Action of Domperidone*Domperidone is a potent dopamine receptor antagonist. It acts centrally and blocks the Dopamine receptor in the Chemoreceptor trigger zone and produces Antiemetic effect. *Domperidone acts peripherally in the gastrointestinal system and increases oesophageal peristalsis, oesophageal sphincter pressure and gastric motility. These all facilitates gastric emptying. Domperidone is used in migraine to relieve nausea and vomiting. *Anaesthetic adjuncts: It is used preoperatively in order to reduce the post operative vomiting. **Indications for Domperidone*1.Nausea and vomiting associated with gastrointestinal disorder and migraine. *2.Delayed gastric emptying of functional origin *3.As an Antiemetic in patient receiving cytotoxic drugs *4.Preanaesthetic medication
FARCOTILIUM 10mg 24 Caps.DOMPERIDONEPHARCO7.75About Domperidone*Antidopaminergic, Motility stimulant,Piperidine derivative, Antiemetic, anti-vertigo.*Mechanism of Action of Domperidone*Domperidone is a potent dopamine receptor antagonist. It acts centrally and blocks the Dopamine receptor in the Chemoreceptor trigger zone and produces Antiemetic effect. *Domperidone acts peripherally in the gastrointestinal system and increases oesophageal peristalsis, oesophageal sphincter pressure and gastric motility. These all facilitates gastric emptying. Domperidone is used in migraine to relieve nausea and vomiting. *Anaesthetic adjuncts: It is used preoperatively in order to reduce the post operative vomiting. **Indications for Domperidone*1.Nausea and vomiting associated with gastrointestinal disorder and migraine. *2.Delayed gastric emptying of functional origin *3.As an Antiemetic in patient receiving cytotoxic drugs *4.Preanaesthetic medication
FARCOTILIUM 10mg infantile supp. (CANCELLED)DOMPERIDONEPHARCO4.5About Domperidone*Antidopaminergic, Motility stimulant,Piperidine derivative, Antiemetic, anti-vertigo.*Mechanism of Action of Domperidone*Domperidone is a potent dopamine receptor antagonist. It acts centrally and blocks the Dopamine receptor in the Chemoreceptor trigger zone and produces Antiemetic effect. *Domperidone acts peripherally in the gastrointestinal system and increases oesophageal peristalsis, oesophageal sphincter pressure and gastric motility. These all facilitates gastric emptying. Domperidone is used in migraine to relieve nausea and vomiting. *Anaesthetic adjuncts: It is used preoperatively in order to reduce the post operative vomiting. **Indications for Domperidone*1.Nausea and vomiting associated with gastrointestinal disorder and migraine. *2.Delayed gastric emptying of functional origin *3.As an Antiemetic in patient receiving cytotoxic drugs *4.Preanaesthetic medication
FARCOVIT B12 30 Caps.CYNARA DRY EXTRACT -- INOSITOL -- OROTIC ACID -- PHOSPHOLIPIDS -- SAFFLOWER OIL -- VITAMINSPHARCOLiver Support Supplement13.5
FARCOZEPAM 5mg 20 tab.DIAZEPAMPHARCOAnti-epileptic.Benzodiazepines4.5About Diazepam*A benzodiazepine derivative with CNS depressant, Anxiolytic, anticonvulsant, hypnotic, sedative, skeletal muscle relaxant and amnestic.**Mechanism of Action of Diazepam*Diazepam mainly acts on Limbic system and ascending reticular formation in the CNS and binds to the BZD receptor. The binding will facilitates GABA mediated chloride channel opening and produce hyperpolarisation. This will produce an increase in the concentration of the inhibitory neurotransmitter GABA and chloride ions and decreases firing rate of neuron. These in turn alters normal functions of the body. *Antivertigo action: Although intravenous diazepam has been used to abort acute attacks of vertigo of peripheral origin, it can prolong compensation and recovery from vestibular lesions **Interactions for Diazepam*Alcohol and other CNS depressants: Enhanced CNS effects. *Aminophylline: Antagonizes the sedative effect. *Cimetidine, Oral contraceptives, Disulfiram, Fluoxetine, Isoniazid
FARCOZOL PLUS 120ml susp.DILOXANIDE FUROATE -- METRONIDAZOLEPHARCOAntiprotozoal.Nitroimidazole6"About Diloxanide Furoate*Dichloroacetamide derivative, anti-protozoal, Luminal amebicides.*Mechanism of Action of Diloxanide Furoate*Diloxanide Furoate is a dicloroacetamide derivative which acts as a luminal amoebicide. It exerts its action by directly killing the trophozoites responsible for production of cysts.**Indications for Diloxanide Furoate*1. Mild intestinal Amoebiasis, *2. Asymptomatic cyst passers of Entamoeba histolitica **Mechanism of action Metronidazole *is a prodrug. Unionized metronidazole is selective for anaerobic bacteria due to their ability to intracellularly reduce metronidazole to its active form. This reduced metronidazole then covalently binds to DNA, disrupt its helical structure, inhibiting bacterial nucleic acid synthesis and resulting in bacterial cell death."
FAWAR COLA 6 sachetsCITRIC ACID -- SODIUM BICARBONTE -- TARTARIC ACIDPHARCO5.25INTERACTIONS:*Antacids*Concurrent use of antacids with citrates may result in systemic alkalosis.*Concomitant administration of antacids with sodium citrate and sodium bicarbonate may promote the development of calcium stones in patients with uric acid stones and may also cause hypernatraemia.*Concurrent use of aluminium-containing antacids with citrate salts can increase aluminium absorption, possibly resulting in acute aluminium toxicity, especially in patients with renal insufficiency.*Quinolones*Citrates may reduce the solubility of ciprofloxacin, norfloxacin, or ofloxacin in the urine. Patients should be observed for signs of crystalluria and nephrotoxicity.*Salicylates
FAWAR FRUIT 6 sachetsCITRIC ACID -- SODIUM BICARBONTE -- TARTARIC ACIDPHARCO6INTERACTIONS:*Antacids*Concurrent use of antacids with citrates may result in systemic alkalosis.*Concomitant administration of antacids with sodium citrate and sodium bicarbonate may promote the development of calcium stones in patients with uric acid stones and may also cause hypernatraemia.*Concurrent use of aluminium-containing antacids with citrate salts can increase aluminium absorption, possibly resulting in acute aluminium toxicity, especially in patients with renal insufficiency.*Quinolones*Citrates may reduce the solubility of ciprofloxacin, norfloxacin, or ofloxacin in the urine. Patients should be observed for signs of crystalluria and nephrotoxicity.*Salicylates
FAWAR FRUIT 60 SACHETSCITRIC ACID -- SODIUM BICARBONTE -- TARTARIC ACIDPHARCO20INTERACTIONS:*Antacids*Concurrent use of antacids with citrates may result in systemic alkalosis.*Concomitant administration of antacids with sodium citrate and sodium bicarbonate may promote the development of calcium stones in patients with uric acid stones and may also cause hypernatraemia.*Concurrent use of aluminium-containing antacids with citrate salts can increase aluminium absorption, possibly resulting in acute aluminium toxicity, especially in patients with renal insufficiency.*Quinolones*Citrates may reduce the solubility of ciprofloxacin, norfloxacin, or ofloxacin in the urine. Patients should be observed for signs of crystalluria and nephrotoxicity.*Salicylates
FAWAR LEMON 6 sachetsCITRIC ACID -- SODIUM BICARBONTE -- TARTARIC ACIDPHARCO5.25INTERACTIONS:*Antacids*Concurrent use of antacids with citrates may result in systemic alkalosis.*Concomitant administration of antacids with sodium citrate and sodium bicarbonate may promote the development of calcium stones in patients with uric acid stones and may also cause hypernatraemia.*Concurrent use of aluminium-containing antacids with citrate salts can increase aluminium absorption, possibly resulting in acute aluminium toxicity, especially in patients with renal insufficiency.*Quinolones*Citrates may reduce the solubility of ciprofloxacin, norfloxacin, or ofloxacin in the urine. Patients should be observed for signs of crystalluria and nephrotoxicity.*Salicylates
FEBRIMOL 500mg 20 tab.PARACETAMOL(ACETAMINOPHEN)PHARCOAntipyretic3.5About Paracetamol*Acetanilide derivative, Non narcotic Analgesic,Antipyretic.*Mechanism of Action of Paracetamol*Paracetamol has analgesic and antipyretic action. *It is more active on cyclo-oxygenase enzyme in brain. Peripherally it is a poor inhibitor of prostaglandin synthesis. *Analgesic action: Paracetamol raises the pain threshold and produces analgesic effect. *Antipyretic action: Paracetamol lowers fever by direct action on the thermoregulatory centre in the Hypothalamus and block the effects of endogenous pyrogen. *Indications for Paracetamol*1. To relieve pain and fever *2. Acute gout *3. Migraine *Interactions for Paracetamol*Cholestyramine: Reduces absorption of paracetamol. *Charcoal: Activated, administered immediately reduces absorption of paracetamol. *Domperidone and metochlopramide: Enhance absorption of paracetamol. *Alcohol: Chronic excessive ingestion of alcohol potentiates hepatotoxicity of paracetamol. *
FEBRIMOL oral drops 20 MLPARACETAMOL(ACETAMINOPHEN)PHARCOAntipyretic4About Paracetamol*Acetanilide derivative, Non narcotic Analgesic,Antipyretic.*Mechanism of Action of Paracetamol*Paracetamol has analgesic and antipyretic action. *It is more active on cyclo-oxygenase enzyme in brain. Peripherally it is a poor inhibitor of prostaglandin synthesis. *Analgesic action: Paracetamol raises the pain threshold and produces analgesic effect. *Antipyretic action: Paracetamol lowers fever by direct action on the thermoregulatory centre in the Hypothalamus and block the effects of endogenous pyrogen. *Indications for Paracetamol*1. To relieve pain and fever *2. Acute gout *3. Migraine *Interactions for Paracetamol*Cholestyramine: Reduces absorption of paracetamol. *Charcoal: Activated, administered immediately reduces absorption of paracetamol. *Domperidone and metochlopramide: Enhance absorption of paracetamol. *Alcohol: Chronic excessive ingestion of alcohol potentiates hepatotoxicity of paracetamol. *
FEMIGIN B vaginal sachetsSIMETHICONE -- SODIUM CHLORIDE -- SODIUM LAURYL SULPHATE -- SODIUM PHOSPHATEPHARCO4A
FERRO-6 24 soft gelatin Caps.COPPER SULPHATE -- FOLIC ACID -- IRON -- MANGANESE SULPHATE -- VITAMIN B12 -- VITAMIN CPHARCOvitamin15.75About Copper*Third most abundant essential trace mineral, A cofactor for many proteins, iron utilization enhancer, Copper deficiency.*Mechanism of Action of Copper*Copper is one of a relatively small group of metallic elements which are essential to human health. These elements, along with amino and fatty acids as well as vitamins, are required for normal metabolic processes.
FOLICAP 0.5mg 24 Caps.FOLIC ACIDPHARCOvitamin6"About Folic Acid*Dietary supplement, Folate derivative( B9 ), Water Soluble Vitamin.**Mechanism of Action of Folic Acid*Folic acid reduced by enzymes folate reductase and dihydrofolate reductase and forms dihydrofolic acid tetrahydrofolic acid respectively. Tetrahydrofolic acid acts as a coenzyme which mediates a number of one carbon transfer reactions by carrying a methyl group as an adduct. It involves a number of reactions such as 1).conversion of homocysteine to methionine. 2).synthesis of thymidylate which is an essential constituent of DNA from methylene-tetrahydrofolic acid. 3). Conversion of serine to glycine by tetrahydrofolic acid and forms methylene-tetrahydrofolic acid. 4).to introduce carbon units at position 2 and 8 during de novo purine synthesis requires formyl-tetrahydrofolic acid and methenyl-tetrahydrofolic acid.5).generation and utilization of ""formate pool"". 6).For mediating formino group transfer in histidine metabolism."
FRUSETONE 20/100 mg 10 F.C.tabFUROSEMIDE -- SPIRONOLACTONEPHARCO11.25"Description *A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for edema and chronic renal insufficiency. *Mechanism of action Furosemide, a loop diuretic, inhibits water reabsorption in the nephron by blocking the sodium-potassium-chloride cotransporter (NKCC2) in the thick ascending limb of the loop of Henle. This is achieved through competitive inhibition at the chloride binding site on the cotransporter, thus preventing the transport of sodium from the lumen of the loop of Henle into the basolateral interstitium. Consequently, the lumen becomes more hypertonic while the interstitium becomes less hypertonic, which in turn diminishes the osmotic gradient for water reabsorption throughout the nephron. Because the thick ascending limb is responsible for 25% of sodium reabsorption in the nephron, furosemide is a very potent diuretic."
FRUSETONE 20/50mg 10 F.C. tabs.FUROSEMIDE -- SPIRONOLACTONEPHARCO7.25"Description *A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for edema and chronic renal insufficiency. *Mechanism of action Furosemide, a loop diuretic, inhibits water reabsorption in the nephron by blocking the sodium-potassium-chloride cotransporter (NKCC2) in the thick ascending limb of the loop of Henle. This is achieved through competitive inhibition at the chloride binding site on the cotransporter, thus preventing the transport of sodium from the lumen of the loop of Henle into the basolateral interstitium. Consequently, the lumen becomes more hypertonic while the interstitium becomes less hypertonic, which in turn diminishes the osmotic gradient for water reabsorption throughout the nephron. Because the thick ascending limb is responsible for 25% of sodium reabsorption in the nephron, furosemide is a very potent diuretic."
G.C. MOL 6 EFF. SachetGUAIFENESIN -- PARACETAMOL(ACETAMINOPHEN) -- VITAMIN CPHARCO5"Description *An expectorant that also has some muscle relaxing action*Mechanism of action Guaifenesin may act as an irritant to gastric vagal receptors, and recruit efferent parasympathetic reflexes that cause glandular exocytosis of a less viscous mucus mixture. Cough may be provoked. This combination may flush tenacious, congealed mucopurulent material from obstructed small airways and lead to a temporary improvement in dyspnea or the work of breathing."
GINSENG 100 MG 24 S.G. CAPS.GINSENGPHARCOTonic8About Ginseng*Steroid glycosides.**Mechanism of Action of Ginseng*It contains chemicals called ginsenosides that seem to affect insulin levels in the body and lower blood sugar. Other chemicals, called polysaccharides, might affect the immune system.**Indications for Ginseng*1.Adaptogen-adapt to internal/external stressors, fight fatigue, increase stamina *2.Lowering blood sugar after a meal in people with type 2 diabetes *3.Preventing respiratory tract infections such as the common cold or influenza in adults *Interactions for Ginseng*1.Warfarin:Ginseng decreases its effectiveness. *2.Medications for diabetes (Antidiabetes drugs). *3.Antidepressants: Panax ginseng might stimulate the body.. Taking Panax ginseng with these medications used for depression might cause too much stimulation. This might cause side effects such as anxiousness, headache, restlessness, and insomnia. *
GINSENG SYRUP 120 MLGINSENGPHARCOTonic5About Ginseng*Steroid glycosides.**Mechanism of Action of Ginseng*It contains chemicals called ginsenosides that seem to affect insulin levels in the body and lower blood sugar. Other chemicals, called polysaccharides, might affect the immune system.**Indications for Ginseng*1.Adaptogen-adapt to internal/external stressors, fight fatigue, increase stamina *2.Lowering blood sugar after a meal in people with type 2 diabetes *3.Preventing respiratory tract infections such as the common cold or influenza in adults *Interactions for Ginseng*1.Warfarin:Ginseng decreases its effectiveness. *2.Medications for diabetes (Antidiabetes drugs). *3.Antidepressants: Panax ginseng might stimulate the body.. Taking Panax ginseng with these medications used for depression might cause too much stimulation. This might cause side effects such as anxiousness, headache, restlessness, and insomnia. *
GLUVILDAN 50 mg 10 tab.VILDAGLIPTINPHARCOAnti-Diabetic.Secretagogues.DPP-4 inhibitors21
GLYCERIN ADULT 5 SUPP. (PHARCO)GELATIN -- GLYCERINPHARCO5.25Mechanism of Action of Glycerine*Glycerine is a sweet clear viscous liquid with dehydrating property. It produces a warm sensation and irritates mucous membranes. When used as a suppository and applied to anal canal it induces evacuation. Glycerine soothes the irritated skin so it is used as a component of cough mixtures. When a 50% solution of Glycerine in water is applied to dry and chapped skin it acts as an emollient. When used a 10% solution I.V. it reduces intraocular or intracranial pressure. When used as a diuretic it significantly increases the osmolality of plasma and tubular fluid. It is pharmacologically inert and freely filtered at glomerulus and undergoes limited reabsorption by renal tubule and acts as osmotic diuretic.
GLYCERIN ICHTHYOL vaginal pessariesGLYCERIN -- ICHTAMMOLPHARCO3.5Mechanism of Action of Glycerine*Glycerine is a sweet clear viscous liquid with dehydrating property. It produces a warm sensation and irritates mucous membranes. When used as a suppository and applied to anal canal it induces evacuation. Glycerine soothes the irritated skin so it is used as a component of cough mixtures. When a 50% solution of Glycerine in water is applied to dry and chapped skin it acts as an emollient. When used a 10% solution I.V. it reduces intraocular or intracranial pressure. When used as a diuretic it significantly increases the osmolality of plasma and tubular fluid. It is pharmacologically inert and freely filtered at glomerulus and undergoes limited reabsorption by renal tubule and acts as osmotic diuretic.
GLYCERIN INFANTILE 5 SUPP. (PHARCO)GELATIN -- GLYCERINPHARCO5.25Mechanism of Action of Glycerine*Glycerine is a sweet clear viscous liquid with dehydrating property. It produces a warm sensation and irritates mucous membranes. When used as a suppository and applied to anal canal it induces evacuation. Glycerine soothes the irritated skin so it is used as a component of cough mixtures. When a 50% solution of Glycerine in water is applied to dry and chapped skin it acts as an emollient. When used a 10% solution I.V. it reduces intraocular or intracranial pressure. When used as a diuretic it significantly increases the osmolality of plasma and tubular fluid. It is pharmacologically inert and freely filtered at glomerulus and undergoes limited reabsorption by renal tubule and acts as osmotic diuretic.
GRIPE BABY WATER 120 MLTERPENELESS DILL SEED OILPHARCO8For flatulence in infants and children
GYNOZOL 2% vaginal cream 40 GMMICONAZOLEPHARCOantifungals.Imidazoles27About Miconazole*An imidazole derivative, Broad spectrum Antifungal.**Mechanism of Action of Miconazole*Miconazole is fungicidal or fungistatic depending on the drug concentrations. I t inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochromeP450 enzyme 14 alpha demethylase and impair ergosterol synthesis*Indications for Miconazole*1.Tinea versicolor *2.Vulvovaginal candidiasis *3.Tinea pedis *4.Tinea corporis *5.Tinea cruris *6.Otomycosis *7.Onychomycosis *8.Oral candidiasis *9.Intestinal candidiasis *10.Diaper dermatitis*
GYNOZOL 200mg 6 VAG. OVULESMICONAZOLEPHARCOantifungals.Imidazoles15About Miconazole*An imidazole derivative, Broad spectrum Antifungal.**Mechanism of Action of Miconazole*Miconazole is fungicidal or fungistatic depending on the drug concentrations. I t inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochromeP450 enzyme 14 alpha demethylase and impair ergosterol synthesis*Indications for Miconazole*1.Tinea versicolor *2.Vulvovaginal candidiasis *3.Tinea pedis *4.Tinea corporis *5.Tinea cruris *6.Otomycosis *7.Onychomycosis *8.Oral candidiasis *9.Intestinal candidiasis *10.Diaper dermatitis*
GYNOZOL 400mg 3 VAG. OVULESMICONAZOLEPHARCOantifungals.Imidazoles15About Miconazole*An imidazole derivative, Broad spectrum Antifungal.**Mechanism of Action of Miconazole*Miconazole is fungicidal or fungistatic depending on the drug concentrations. I t inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochromeP450 enzyme 14 alpha demethylase and impair ergosterol synthesis*Indications for Miconazole*1.Tinea versicolor *2.Vulvovaginal candidiasis *3.Tinea pedis *4.Tinea corporis *5.Tinea cruris *6.Otomycosis *7.Onychomycosis *8.Oral candidiasis *9.Intestinal candidiasis *10.Diaper dermatitis*
HAIR GAIN 2% lotionMINOXIDILPHARCOAntihypertensives.Hair regrowth.Vasodilator Agents30About Minoxidil*A potassium channel agonist,Direct-Acting Vasodilator, Hair- growth stimulant,In androgenic alopecia.**Mechanism of Action of Minoxidil*Minoxidil works by activating PGHS 1 (prostaglandin endoperoxide synthase-1) which helps promote hair growth. It enhances follicular size and results in thicker hair shafts and stimulates and prolongs the anagen phase of the hair cycle. This will results in longer and increased number of hairs.**Indications for Minoxidil*1. Alopecia areata *2. Androgenic alopecia
HALOTHANE-PHARCO (100ml) inhalerHALOTHANEPHARCO45About Halothane*Haloalkane derivative, Inhalation General Anesthetic.**Mechanism of Action of Halothane*Halothane will alter presynaptic activity and the release of neurotransmitters due to alterations in intracellular signaling. Halothane similarly inhibit non-NMDA and NMDA receptor-mediated excitatory postsynaptic currents in both cell types at low concentrations but preferentially blocked responses to exogenously applied AMPA at higher concentrations. Synaptically but not directly evoked action potentials in interneurons were inhibited by halothane.**Indications for Halothane*1. Inhalational anaesthesia *2. Operations where blood-less field is required
HALOTHANE-PHARCO (250ml) inhalerHALOTHANEPHARCO80About Halothane*Haloalkane derivative, Inhalation General Anesthetic.**Mechanism of Action of Halothane*Halothane will alter presynaptic activity and the release of neurotransmitters due to alterations in intracellular signaling. Halothane similarly inhibit non-NMDA and NMDA receptor-mediated excitatory postsynaptic currents in both cell types at low concentrations but preferentially blocked responses to exogenously applied AMPA at higher concentrations. Synaptically but not directly evoked action potentials in interneurons were inhibited by halothane.**Indications for Halothane*1. Inhalational anaesthesia *2. Operations where blood-less field is required
HERBARIL topical gel 40 GMAESCIN -- DIETHYLAMINE SALICYLATEPHARCONSAID.Antirehumatic.Salicylates9Indications :**- In cases of contusions, crush injuries, sprains .bruises, haematoma and tenosynovitis.*- Painful conditions of the vertebral column (disc lesions, neck pain, lumbago, sciatica).*- In superficial thrombophlebitis ,varicose veins ,for care of*- the veins after injections or infusions.**Contraindications :**Hypersensitivity to any of the drug components. Reparil-Gel N should not be applied to eyes, broken skin, mucous membranes or skin areas exposed to radiotherapy.
HICONCIL 100gm/ml paed.dropsAMOXICILLINPHARCOPenicillins.Monocomponent7.5(Indications):* is a penicillin-like , beta-lactam antibiotic. It is used to treat bacterial infections caused by susceptible microorganisms. It prevents the bacterial growth and is used in the treatment of a number of infections such as pneumonia, bronchitis, gonorrhea, and infections of the ears, nose, throat, urinary tract, and skin. * *(Dosage):*Adult : 250 mg to 500 mg 3 times/day*Child : The recommended dose is 25 mg/kg/day in divided doses every 12 hours. ***
HICONCIL 125mg/5ml 60ml susp.AMOXICILLINPHARCOPenicillins.Monocomponent7(Indications):* is a penicillin-like , beta-lactam antibiotic. It is used to treat bacterial infections caused by susceptible microorganisms. It prevents the bacterial growth and is used in the treatment of a number of infections such as pneumonia, bronchitis, gonorrhea, and infections of the ears, nose, throat, urinary tract, and skin. * *(Dosage):*Adult : 250 mg to 500 mg 3 times/day*Child : The recommended dose is 25 mg/kg/day in divided doses every 12 hours. ***
HICONCIL 125mg/5ml 80ml susp.AMOXICILLINPHARCOPenicillins.Monocomponent8(Indications):* is a penicillin-like , beta-lactam antibiotic. It is used to treat bacterial infections caused by susceptible microorganisms. It prevents the bacterial growth and is used in the treatment of a number of infections such as pneumonia, bronchitis, gonorrhea, and infections of the ears, nose, throat, urinary tract, and skin. * *(Dosage):*Adult : 250 mg to 500 mg 3 times/day*Child : The recommended dose is 25 mg/kg/day in divided doses every 12 hours. ***
HICONCIL 250mg 12Caps.AMOXICILLINPHARCOPenicillins.Monocomponent6.5(Indications):* is a penicillin-like , beta-lactam antibiotic. It is used to treat bacterial infections caused by susceptible microorganisms. It prevents the bacterial growth and is used in the treatment of a number of infections such as pneumonia, bronchitis, gonorrhea, and infections of the ears, nose, throat, urinary tract, and skin. * *(Dosage):*Adult : 250 mg to 500 mg 3 times/day*Child : The recommended dose is 25 mg/kg/day in divided doses every 12 hours. ***
HICONCIL 250mg/5ml 60ml susp.AMOXICILLINPHARCOPenicillins.Monocomponent7(Indications):* is a penicillin-like , beta-lactam antibiotic. It is used to treat bacterial infections caused by susceptible microorganisms. It prevents the bacterial growth and is used in the treatment of a number of infections such as pneumonia, bronchitis, gonorrhea, and infections of the ears, nose, throat, urinary tract, and skin. * *(Dosage):*Adult : 250 mg to 500 mg 3 times/day*Child : The recommended dose is 25 mg/kg/day in divided doses every 12 hours. ***
HICONCIL 250mg/5ml 80ml susp.AMOXICILLINPHARCOPenicillins.Monocomponent11(Indications):* is a penicillin-like , beta-lactam antibiotic. It is used to treat bacterial infections caused by susceptible microorganisms. It prevents the bacterial growth and is used in the treatment of a number of infections such as pneumonia, bronchitis, gonorrhea, and infections of the ears, nose, throat, urinary tract, and skin. * *(Dosage):*Adult : 250 mg to 500 mg 3 times/day*Child : The recommended dose is 25 mg/kg/day in divided doses every 12 hours. ***
HICONCIL 500mg 12 Caps.AMOXICILLINPHARCOPenicillins.Monocomponent11.6(Indications):* is a penicillin-like , beta-lactam antibiotic. It is used to treat bacterial infections caused by susceptible microorganisms. It prevents the bacterial growth and is used in the treatment of a number of infections such as pneumonia, bronchitis, gonorrhea, and infections of the ears, nose, throat, urinary tract, and skin. * *(Dosage):*Adult : 250 mg to 500 mg 3 times/day*Child : The recommended dose is 25 mg/kg/day in divided doses every 12 hours. ***
HYDIKAL 20 tab.AMILORIDE -- HYDROCHLOROTHIAZIDEPHARCODiuretic.Combined thiazide with Potassium-sparing6Pregnancy Related Information*Contraindicated- since Amiloride and Hydrochlorothiazide are contraindicated in pregnancy.*Breast Feeding Related Information*Contraindicated- since Amiloride and Hydrochlorothiazide are contraindicated in lactation.*Indications for Amiloride -- Hydrochlorothiazide*Hypertention*Typical Dosage for Amiloride -- Hydrochlorothiazide*Adults: 1 - 2 tablets / day preferably in the morning (Amiloride 5mg -- Hydrochlorothiazide 50mg )*Mechanism of Action of Amiloride*Amiloride is a guanidine derivative which exerts its diuretic action by interacting with renal epithelial Na -- channels in distal tubules and collecting duct and prevents sodium reabsorption. It prevents potassium lose. It also increases chloride, bicarbonate, and water excretion and decreases H -- excretion. The drug augment the natriuretic and anti hypertensive response of other drugs.
HYPOTEN 30 tab.CLOPAMIDE -- DIHYDROERGOTOXINE -- RESERPINEPHARCO8About Clopamide*A piperidine diuretic, sulfamyl, thiazide like diuretics, Anti hypertensive ,diuretic.*Mechanism of Action of Clopamide*It exerts thiazides like diuretic action by acting at site-3(central dilating segment of early distal tubule). It binds to Na -- -Cl- symporter and inhibits Na -- -Cl- symport at the luminal membrane. It increases natriuresis, kaliuresis and diuresis. It decreases Ca2 -- excretion and increases Mg2 -- and hence used to correct hypocalcaemia. It also reduces glomerular filtration rate. The antihypertensive actions of the drug may be attributable to depletion of sodium and subsequent reduction in plasma volume and a decrease in peripheral resistance. Decrease in peripheral resistance is due to either the loss of sodium from the arteriolar wall or a direct action on the vascular bed. It is an effective drug in edema associated with congestive heart failure.
INDOMETHACIN 1% topical SPRAY 50 MLINDOMETHACINPHARCONSAID.Acetic acid derivatives14.4About Indomethacin*NSAID, Indole derivative, Anti-inflammatory, potent antipyretic and analgesic.**Mechanism of Action of Indomethacin*Indomethacin acts by inhibition of Prostaglandin (PGs) synthesis and their release at the site of injury. Prostaglandins cause tenderness and amplify the action of other algesics. Indomethacin does not affect the tenderness induced by PGs but block the pain producing mechanism induced by inflammatory mediators by inhibiting the enzyme cyclo-oxygenase. **Interactions for Indomethacin*Anticoagulants: May prolong prothrombin time. Instruct patients to watch for signs & symptoms of bleeding. *Beta-Blockers: Antihypertensive effect may be blunted. *Cyclosporine: Nephrotoxicity of both agents may be increased. *Digoxin: Serum digoxin levels may be increased by ibuprofen and indomethacin. *Hydantoins: Serum hydantoin levels increased resulting in increased pharmacological and toxic effects. *Lithium: Serum lithium levels may be increased. *
INDOMETHACIN 25mg 24 Caps.INDOMETHACINPHARCONSAID.Acetic acid derivatives4.75About Indomethacin*NSAID, Indole derivative, Anti-inflammatory, potent antipyretic and analgesic.**Mechanism of Action of Indomethacin*Indomethacin acts by inhibition of Prostaglandin (PGs) synthesis and their release at the site of injury. Prostaglandins cause tenderness and amplify the action of other algesics. Indomethacin does not affect the tenderness induced by PGs but block the pain producing mechanism induced by inflammatory mediators by inhibiting the enzyme cyclo-oxygenase. **Interactions for Indomethacin*Anticoagulants: May prolong prothrombin time. Instruct patients to watch for signs & symptoms of bleeding. *Beta-Blockers: Antihypertensive effect may be blunted. *Cyclosporine: Nephrotoxicity of both agents may be increased. *Digoxin: Serum digoxin levels may be increased by ibuprofen and indomethacin. *Hydantoins: Serum hydantoin levels increased resulting in increased pharmacological and toxic effects. *Lithium: Serum lithium levels may be increased. *
INDOMETHACIN 50mg 24 Caps.INDOMETHACINPHARCONSAID.Acetic acid derivatives5.25About Indomethacin*NSAID, Indole derivative, Anti-inflammatory, potent antipyretic and analgesic.**Mechanism of Action of Indomethacin*Indomethacin acts by inhibition of Prostaglandin (PGs) synthesis and their release at the site of injury. Prostaglandins cause tenderness and amplify the action of other algesics. Indomethacin does not affect the tenderness induced by PGs but block the pain producing mechanism induced by inflammatory mediators by inhibiting the enzyme cyclo-oxygenase. **Interactions for Indomethacin*Anticoagulants: May prolong prothrombin time. Instruct patients to watch for signs & symptoms of bleeding. *Beta-Blockers: Antihypertensive effect may be blunted. *Cyclosporine: Nephrotoxicity of both agents may be increased. *Digoxin: Serum digoxin levels may be increased by ibuprofen and indomethacin. *Hydantoins: Serum hydantoin levels increased resulting in increased pharmacological and toxic effects. *Lithium: Serum lithium levels may be increased. *
IODOSEPT 10% 120ml mouthwashPOVIDONE- IODINEPHARCO6About Povidone Iodine*Iodine preparation, External broad microbicidal spectrum antiseptic.*Mechanism of Action of Povidone Iodine*Povidone iodine is an iodophore antiseptic and is a microbicidal drug. It releases iodine from its complex and produces pharmacological actions. The released iodine produces antiseptic actions. Iodine is highly reactive with surrounding and has strong oxidizing effect on functional groups of amino acids (-NH 2, -SH etc.), Nucleotides, and fatty acids (double bond of unsaturated fatty acids). Interaction of Iodine with these groups in a cell results in disintegration of the cytoplasm, enzyme denaturation, loss of integrity in the bacterial cell membrane and fungal cell wall .These will leads to destruction of microbial protein and DNA and finally kills the microbes.
IODOSEPT 10% 60ml mouthwashPOVIDONE- IODINEPHARCO4About Povidone Iodine*Iodine preparation, External broad microbicidal spectrum antiseptic.*Mechanism of Action of Povidone Iodine*Povidone iodine is an iodophore antiseptic and is a microbicidal drug. It releases iodine from its complex and produces pharmacological actions. The released iodine produces antiseptic actions. Iodine is highly reactive with surrounding and has strong oxidizing effect on functional groups of amino acids (-NH 2, -SH etc.), Nucleotides, and fatty acids (double bond of unsaturated fatty acids). Interaction of Iodine with these groups in a cell results in disintegration of the cytoplasm, enzyme denaturation, loss of integrity in the bacterial cell membrane and fungal cell wall .These will leads to destruction of microbial protein and DNA and finally kills the microbes.
IODOSEPT 10% topical solutionPOVIDONE- IODINEPHARCO4About Povidone Iodine*Iodine preparation, External broad microbicidal spectrum antiseptic.*Mechanism of Action of Povidone Iodine*Povidone iodine is an iodophore antiseptic and is a microbicidal drug. It releases iodine from its complex and produces pharmacological actions. The released iodine produces antiseptic actions. Iodine is highly reactive with surrounding and has strong oxidizing effect on functional groups of amino acids (-NH 2, -SH etc.), Nucleotides, and fatty acids (double bond of unsaturated fatty acids). Interaction of Iodine with these groups in a cell results in disintegration of the cytoplasm, enzyme denaturation, loss of integrity in the bacterial cell membrane and fungal cell wall .These will leads to destruction of microbial protein and DNA and finally kills the microbes.
IODOSEPT 10% VAGINAL DOUCHE 120 MLPOVIDONE- IODINEPHARCO6About Povidone Iodine*Iodine preparation, External broad microbicidal spectrum antiseptic.*Mechanism of Action of Povidone Iodine*Povidone iodine is an iodophore antiseptic and is a microbicidal drug. It releases iodine from its complex and produces pharmacological actions. The released iodine produces antiseptic actions. Iodine is highly reactive with surrounding and has strong oxidizing effect on functional groups of amino acids (-NH 2, -SH etc.), Nucleotides, and fatty acids (double bond of unsaturated fatty acids). Interaction of Iodine with these groups in a cell results in disintegration of the cytoplasm, enzyme denaturation, loss of integrity in the bacterial cell membrane and fungal cell wall .These will leads to destruction of microbial protein and DNA and finally kills the microbes.
KETOTI PHARCO 1 mg 20 tab.KETOTIFENPHARCOAnti-histamine.Second-Generation10.5About Ketotifen*Second Generation H1 Antagonist, Mast Cell Stabilizer, Antihistamine.**Mechanism of Action of Ketotifen*It is a mast cell stabilizer. This inhibit the development of airway hyper reactivity (associated with activation of platelets by PAF (Platelet Activating Factor) or caused by neural activation following the use of sympathomimetic drugs or the exposure to allergen) by suppressing the priming of eosinophils by human recombinant cytokines and thereby suppression of the influx of eosinophils into inflammatory site. In addition, Ketotifen is a potent antiallergic substance possessing a powerful and sustained noncompetitive histamine (H 1) blocking property. **Indications for Ketotifen*1. Rhinitis *2. Conjunctivitis *3. Prophylaxis for bronchial asthma *Interactions for Ketotifen*Sedatives, Hypnotics & Alcohol: May potentiate the effects of these agents, leading to CNS depression. *Oral antidiabetics: Avoid as fall in thrombocyte count reported. *
KETOTI PHARCO 1mg/5ml 120ml syrupKETOTIFENPHARCOAnti-histamine.Second-Generation10About Ketotifen*Second Generation H1 Antagonist, Mast Cell Stabilizer, Antihistamine.**Mechanism of Action of Ketotifen*It is a mast cell stabilizer. This inhibit the development of airway hyper reactivity (associated with activation of platelets by PAF (Platelet Activating Factor) or caused by neural activation following the use of sympathomimetic drugs or the exposure to allergen) by suppressing the priming of eosinophils by human recombinant cytokines and thereby suppression of the influx of eosinophils into inflammatory site. In addition, Ketotifen is a potent antiallergic substance possessing a powerful and sustained noncompetitive histamine (H 1) blocking property. **Indications for Ketotifen*1. Rhinitis *2. Conjunctivitis *3. Prophylaxis for bronchial asthma *Interactions for Ketotifen*Sedatives, Hypnotics & Alcohol: May potentiate the effects of these agents, leading to CNS depression. *Oral antidiabetics: Avoid as fall in thrombocyte count reported. *
LAXIN 10mg 20 enteric coated tab.BISACODYLPHARCO3.25About Bisacodyl*Diphenyl methane derivative ,Stimulant (irritant)Laxative**Mechanism of Action of Bisacodyl*Bisacodyl is a stimulant (irritant) laxative. It acts directly on the colonic mucosa-where it stimulates sensory nerve endings in the walls of the intestine and the rectum to produce parasympathetic reflexes resulting in increased peristaltic contractions of the colon and cause defecation.**Indications for Bisacodyl*1.Bowel evacuation in prior to radiological examinations *2.Constipation *3.Laxative in postoperative, ante partum, or postpartum care**Contra-indications of Bisacodyl*1.Hypersensitivity to Bisacodyl *2.Intestinal obstruction *3.Obstruction of the intestines due to loss of intestinal movement *4.Severe dehydration *5.Sudden abdominal conditions requiring surgery (appendicitis) *6.Sudden attacks of inflammatory bowel disease (ulcerative colitis or Crohn`s disease) *7.Anal fissure *8.Ulcerative proctitis
LOMEXCURE 3mg/ml eye drops 5 MLLOMEFLOXACINPHARCOAntibiotic.quinolone9.25About Lomefloxacin*A second generation fluoroquinolone antibiotic, Antibiotic.**Mechanism of Action of Lomefloxacin*Lomefloxacin is a bactericidal drug. It act by inhibiting the enzyme DNA gyrase (Topoisomerase 2) and Topoisomerase 4.DNA gyrase helps in the formation of a highly condensed three dimensional structure of the DNA by its nicking and closing activity and also by introducing negative supercoil in to the DNA double helix. Lomefloxacin inhibits DNA gyrase which results in abnormal linkage between opened DNA and gyrase and negative supercoiling is also impaired. This will inhibits transcription of DNA in to RNA and subsequent protein synthesis.**Indications for Lomefloxacin*1.Urinary tract infection *2.Bronchitis *3.Gonorrhoea *4.Skin and soft tissue infections**Interactions for Lomefloxacin*Antacids (Aluminium/Magnesium hydroxide), Iron salts, Sucralfate, Zinc salts: Decreases absorption of lomefloxacin resulting in reduced serum levels. *
LORAL 30mg 10 Caps.LANZOPRAZOLPHARCOPeptic Ulcer.proton pump inhibitor30"Description *Lansoprazole is a proton pump inhibitor which prevents the stomach from producing acid. It is manufactured by TAP Pharmaceutical Products**Mechanism of action *Lansoprazole belongs to a class of antisecretory compounds, the substituted benzimidazoles, that do not exhibit anticholinergic or histamine H2-receptor antagonist properties, but rather suppress gastric acid secretion by specific inhibition of the (H -- ,K -- )-ATPase enzyme system at the secretory surface of the gastric parietal cell. Because this enzyme system is regarded as the acid (proton) pump within the parietal cell, Lansoprazole has been characterized as a gastric acid-pump inhibitor, in that it blocks the final step of acid production. This effect is dose-related and leads to inhibition of both basal and stimulated gastric acid secretion irrespective of the stimulus."
MENTHOLAX HERBAL 24 Caps.PEPPERMINT -- SENNAPHARCO6.5Peppermint oil is derived from the peppermint plant -- a cross between water mint and spearmint -- that thrives in Europe and North America.**Peppermint oil is commonly used as flavoring in foods and beverages and as a fragrance in soaps and cosmetics. Peppermint oil also is used for a variety of health conditions and can be taken orally in dietary supplements or topically as a skin cream or ointment.
MENTOTHICONE 12 Caps.PEPPERMINT OIL -- SIMETHICONEPHARCO5.5Peppermint oil is derived from the peppermint plant -- a cross between water mint and spearmint -- that thrives in Europe and North America.**Peppermint oil is commonly used as flavoring in foods and beverages and as a fragrance in soaps and cosmetics. Peppermint oil also is used for a variety of health conditions and can be taken orally in dietary supplements or topically as a skin cream or ointment.
MIOPAN 10.8gm/100ml 100ml susp.MAGALDRATEPHARCO6About Magaldrate*Chemical complex of aluminum and magnesium hydroxides, Antacid.**Mechanism of Action of Magaldrate*This neutralizes the gastric acid and increases the gastric pH. This reduces the direct acid irritant effect. It also enhances mucosal barrier integrity and improves gastroesophageal sphincter tone.**Indications for Magaldrate*1. Peptic ulcer *2. Gastritis *3. Reflux oesophagitis *4. Gastric hyperacidity
MIOPAN PLUS 100ml susp.MAGALDRATE -- SIMETHICONEPHARCO6About Magaldrate*Chemical complex of aluminum and magnesium hydroxides, Antacid.*Mechanism of Action of Magaldrate*This neutralizes the gastric acid and increases the gastric pH. This reduces the direct acid irritant effect. It also enhances mucosal barrier integrity and improves gastroesophageal sphincter tone.**Simethicone*About Simethicone*Oral anti-foaming agent, Silicones, Antiflatulent.*Mechanism of Action of Simethicone*This anti-gas (anti-flatulence) medication acts in the stomach and intestines to change the surface tension of gas bubbles, enabling smaller bubbles to join together into bigger bubbles. It results elimination of gas more easily by belching or passing flatus.
MIRAZID 300 MG 12 CAPS.COMMIPHORA MOLMOL EXT.PHARCOAnthelmintic24
MOLFEN 6 sachetsCAFFEINE -- PARACETAMOL(ACETAMINOPHEN)PHARCO4mechanism:*It is thought paracetamol reduces fever by affecting an area of the brain that regulates our body temperature (the hypothalamic heat-regulating center).*Paracetamol is about as effective as aspirin or ibuprofen at relieving mild to moderate pain and fever, but unlike aspirin and ibuprofen it has no anti-inflammatory effect.*Caffeine is a mild stimulant that helps reduce fatigue. Caffeine is also thought to enhance the painkilling effect of paracetamol.**What is it used for?*Mild to moderate pain, such as headache, migraine, toothache, sore throat, muscular and rheumatic pain, nerve pain (neuralgia), backache (lumbago) and period pain.*Relieving aches, pains, sore throat and fever associated with colds and flu.***
MOMENTUM 300mg 24 Caps.HYPERICUMPHARCOpsychiatric.Mood stabilizers14.4"Mechanism of action *Hyperforin is believed to be the primary active constituent responsible for the antidepressant and anxiolytic properties of the extracts of St. John s wort. It acts as a reuptake inhibitor of monoamines, including serotonin, norepinephrine, dopamine, and of GABA and glutamate, with IC50 values of 0.05-0.10 mcg/ml for all compounds, with the exception of glutamate, which is in the 0.5 mcg/ml range. It appears to exert these effects by activating the transient receptor potential ion channel TRPC6. Activation of TRPC6 induces the entry of sodium and calcium into the cell which causes inhibition of monoamine reuptake."
MUCOFAR 15mg/5ml 120ml syrupAMBROXOLPHARCO7"(Indications):*This medication is a mucolytic agent, prescribed for various respiratory diseases such as emphysema with bronchitis pneumoconiosis, chronic inflammatory pulmonary conditions, tracheobronchitis (respiratory tract inflammation), bronchiectasis, bronchitis with bronchospasm asthma. **(dosage) :* The recommended dose is 30-120 mg/day in 2-3 divided doses.**(Warnings and Precautions) : * Caution needed for pregnant and breastfeeding women.*"
NEO-DIGESTIN 120ml syrupPAPAIN -- PEPSIN -- SANZYME 3500PHARCO5.5About Pepsin*A digestive protease, A digestive aid.*Indications for Pepsin*1.Improve blood circulation *2.Prevent abnormal blood clotting. *3.Reduce pain and inflammation associated with Phlebitis. *4.Alleviate the pain, inflammation, and discomfort of varicose veins. *5.Minimize muscle pain that occurs after exercise. *6.Minimize the inflammation and pain associated with Osteoarthritis and Rheumatoid Arthritis. *7.Alleviate the symptoms of Sinusitis. *8.Alleviate oedema.*Papain*About Papain*A fruit-derived cysteine protease enzyme present in papaya, Dietary supplement, a digestive aid.*Indications for Papain*1.Improve blood circulation *2.Prevent abnormal blood clotting. *3.Reduce pain and inflammation associated with Phlebitis. *4.Alleviate the pain, inflammation, and discomfort of varicose veins. *5.Minimize muscle pain that occurs after exercise. *6.Minimize the inflammation and pain associated with Osteoarthritis and Rheumatoid Arthritis. *7.Alleviate the symp
NERVALTA 60mg 10 DELAYED RELEASE Caps.DULOXETINEPHARCOpsychiatric.Antidepressants55About Duloxetine*A serotonin-norepinephrine reuptake inhibitor,Thiophene derivative, Antidepressant.**Mechanism of Action of Duloxetine*Duloxetine preferentially inhibits the re-uptake of Noradrenaline and Serotonin (5 HT) in the CNS nerve terminals .This will result in an increased concentration of neurotransmitter Serotonin in the synaptic cleft and produces antidepressant effect**Indications for Duloxetine*1. Major depressive disorder *2. Diabetic Peripheral Neuropathic Pain *3. Generalised anxiety disorder **Typical Dosage for Duloxetine*Major Depressive Disorder: 20 - 60mg / day in 2 divided doses *Diabetic Peripheral Neuropathic Pain:60 mg/day *Generalized Anxiety Disorder: 60 mg/ day
NIMODIPINE 30 MG 30 TABS.NIMODIPINEPHARCO60About Nimodipine*A dihydropyridine calcium channel blocker, Treatment of neurologic defects associated with subarachnoid hemorrhage.*Mechanism of Action of Nimodipine*Nimodipine is a Ca channel blocker. It exerts its actions through blocking the influx of Ca ions through voltage gated L-type Ca channels to the vascular smooth muscle and resulting in relaxation of vascular smooth muscles. Being highly lipophilic it has greater action on the cerebral vessels.*Indications for Nimodipine*1. Prevention of cerebral vasospasm and resultant ischemia following subarachnoid haemorrhage.*Interactions for Nimodipine*Other calcium channel blockers: Increase its effect. *Phenytoin & caffeine: Increased toxicity of these drugs due to decreased hepatic metabolism.
OCCUMYCINE EYE DROPS 5 MLCHLORAMPHENICOL -- DEXAMETHASONEPHARCO5.5About Chloramphenicol*Bacteriostatic antibiotic, A systemic broad ? spectrum antibacterial agent.*Mechanism of Action of Chloramphenicol*Chloramphenicol is a broad spectrum antibiotic which is primarily bacteriostatic & exerts some bactericidal action at higher concentration. It acts by inhibiting bacterial protein synthesis. Chloramphenicol attaches to 50S subunit of ribosome and interfering with transfer of elongating peptide chain to the newly attached aminoacyl-tRNA at the ribosome-m RNA complex. It prevents the access of aminoacyl-tRNA to the acceptor site for amino acid incorporation. By acting as a peptide analogue it inhibits peptide bond formation
OPRASTA 5mg/100ml soln. for inf. 100 MLZOLEDRONIC ACIDPHARCOOsteoporosis.Bisphosphonates1265About Zoledronic acid*Third-generation bisphosphonate, Osteoclastic bone resorption inhibitor(Calcium regulator).*Mechanism of Action of Zoledronic acid*Zoledronate is a third generation bisphosphonate. It is an analogue of pyrophosphate in which the P-O-P bond is replaced by a non hydrolysable P-C-P bond. With divalent cation such as Ca2 -- (calcium ion) in the bone, they can capable to form chelating complex and form a three dimensional structure. It has high affinity for active remodeling site in the bone. Bisphosphonate retard formation and dissolution of hydroxy apatite crystals within bone and other site. Bisphosphonate remain in the matrix until the bone is remolded and then released in the acid environment of the resorption lacunae beneath the osteoclasts as the overlying mineral matrix is dissolved. It produces antiresorptive action by osteoclasts apoptosis activity and by inhibition of components of the cholesterol biosynthetic pathway.
ORNITATE 3GM 10 SACHETSL-ORNITHINE-L-ASPARTATEPHARCO50"(Indications) : This medication is a stable salt of the amino acids ornithine and aspartic acid, prescribed for the treatment of high ammonia levels or severe liver impairment. It is also used for end-stage cirrhosis. **(Contraindications): *Contraindicated in patients with elevated level of liver enzymes. **Side Effects : *Transient nausea and vomiting.*"
ORNITATE 5gm/10ml 5 amp. For I.V. inf.L-ORNITHINE-L-ASPARTATEPHARCO53"(Indications) : This medication is a stable salt of the amino acids ornithine and aspartic acid, prescribed for the treatment of high ammonia levels or severe liver impairment. It is also used for end-stage cirrhosis. **(Contraindications): *Contraindicated in patients with elevated level of liver enzymes. **Side Effects : *Transient nausea and vomiting.*"
OTOCALM EAR DROPS 10 MLCHLOROBUTANOL -- PHENAZONEPHARCO3.75Analgesic and antiseptic
PARACETAMOL 500mg 20tab. B.P.80PARACETAMOL(ACETAMINOPHEN)PHARCOAntipyretic1.5About Paracetamol*Acetanilide derivative, Non narcotic Analgesic,Antipyretic.*Mechanism of Action of Paracetamol*Paracetamol has analgesic and antipyretic action. *It is more active on cyclo-oxygenase enzyme in brain. Peripherally it is a poor inhibitor of prostaglandin synthesis. *Analgesic action: Paracetamol raises the pain threshold and produces analgesic effect. *Antipyretic action: Paracetamol lowers fever by direct action on the thermoregulatory centre in the Hypothalamus and block the effects of endogenous pyrogen. *Indications for Paracetamol*1. To relieve pain and fever *2. Acute gout *3. Migraine *Interactions for Paracetamol*Cholestyramine: Reduces absorption of paracetamol. *Charcoal: Activated, administered immediately reduces absorption of paracetamol. *Domperidone and metochlopramide: Enhance absorption of paracetamol. *Alcohol: Chronic excessive ingestion of alcohol potentiates hepatotoxicity of paracetamol. *
PHARCOBENZYL 25% lotion 120 MLBENZYL BENZOATEPHARCO4.5Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei. It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection. Benzyl benzoate is lethal to this mite and so is useful in the treatment of scabies. It is also used to treat lice infestation of the head and body. Benzyl benzoate is not the treatment of choice for scabies due to its irritant properties.
PHARCO-VAP oint.CAMPHOR -- EUCALYPTUS OIL -- MENTHOL -- METHYL SALICYLATE -- THYMOLPHARCO6.25Mechanism of Action of Camphor*Camphor acts as a rubefacient when it is rubbed on the skin and causes localized vasodilatation- which gives feelings of comfort and warmth. When applied gently on the skin, it acts as an anti-pruritic agent and creates a feeling of coolness, and a mild local anaesthetic effect and relieves itching. When ingested in small amounts, it creates feelings of warmth and comfort in the epigastrium. Camphor acts as a local anesthetic on the respiratory passageways and causing cough suppression.*Pharmacokinets of Camphor*Absorption: Well absorbed through the skin, Distribution: Widely distributed in the body and crosses the placenta, Metabolism: Metabolized in liver, Excretion: Excreted mainly through urine and a minor portion is excreted through lungs.
PHRAGRA 25 mg 4 F.C.tab.SILDENAFILPHARCOSexual tonic9About Sildenafil Citrate*Phosphodiesterase-5 Enzyme Inhibitor, Anti-erectile dysfunction agent.*Mechanism of Action of Sildenafil Citrate*Sildenafil is a phosphodiesterase enzyme (PDE5) inhibitor. This enzyme is responsible for the degradation cyclic guanosine monophosphate (cGMP) produced in reaction to sexual stimulation. The more cGMP is available, the more durable the erection. Sildenafil inhibits the PDE5 enzyme, preserving cGMP levels, therefore aiding erection viability and durability *Erection of the penis is caused by the filling of the penis with blood. Filling occurs because the blood vessels that bring blood to the penis increase in size and deliver more blood to the penis and at the same time, the blood vessels that take blood away from the penis decrease in size and remove less blood from the penis. *Sexual stimulation that leads to an erection causes the production and release of nitric oxide in the corpora cavernosa of the penis.
PIROXIFAR 0.5% topical gel 30 GMPIROXICAMPHARCONSAID.Oxicam8About Piroxicam*NSAID,Oxicam derivative, Analgesic,antiinflammatory.*Mechanism of Action of Piroxicam*Drug inhibits the biosynthesis and release of prostaglandins by inhibiting cyclooxygenase enzyme in a reversible manner. In this way it reduces the PG (Prostaglandin) concentration in the synovial fluid. It also reduces platelet aggregation (prolong bleeding time), production of IgM rheumatoid factor, chemotaxis of leukocytes and ratio of T-helper to T- suppressor lymphocytes.*Indications for Piroxicam*1. Rheumatoid arthritis *2. Osteoarthritis *3. Ankylosing spondylitis *4. Acute musculo-skeletal disorders *5. Acute gout *6. Post-operative & post-traumatic pain *7. Primary dysmenorrhea *Interactions for Piroxicam*Anticoagulants: May prolong prothrombin time. *Beta-Blockers: Antihypertensive effect may be impaired. *Cyclosporine: Nephrotoxicity of both agents may be increased. *Lithium: Serum lithium levels may be increased. *Hydantoins: Serum hydantoin levels increase
PIROXIFAR 20mg 10 dispersable tab.PIROXICAMPHARCONSAID.Oxicam8.5About Piroxicam*NSAID,Oxicam derivative, Analgesic,antiinflammatory.*Mechanism of Action of Piroxicam*Drug inhibits the biosynthesis and release of prostaglandins by inhibiting cyclooxygenase enzyme in a reversible manner. In this way it reduces the PG (Prostaglandin) concentration in the synovial fluid. It also reduces platelet aggregation (prolong bleeding time), production of IgM rheumatoid factor, chemotaxis of leukocytes and ratio of T-helper to T- suppressor lymphocytes.*Indications for Piroxicam*1. Rheumatoid arthritis *2. Osteoarthritis *3. Ankylosing spondylitis *4. Acute musculo-skeletal disorders *5. Acute gout *6. Post-operative & post-traumatic pain *7. Primary dysmenorrhea *Interactions for Piroxicam*Anticoagulants: May prolong prothrombin time. *Beta-Blockers: Antihypertensive effect may be impaired. *Cyclosporine: Nephrotoxicity of both agents may be increased. *Lithium: Serum lithium levels may be increased. *Hydantoins: Serum hydantoin levels increase
PIROXIFAR 20mg 5 supp.PIROXICAMPHARCONSAID.Oxicam4About Piroxicam*NSAID,Oxicam derivative, Analgesic,antiinflammatory.*Mechanism of Action of Piroxicam*Drug inhibits the biosynthesis and release of prostaglandins by inhibiting cyclooxygenase enzyme in a reversible manner. In this way it reduces the PG (Prostaglandin) concentration in the synovial fluid. It also reduces platelet aggregation (prolong bleeding time), production of IgM rheumatoid factor, chemotaxis of leukocytes and ratio of T-helper to T- suppressor lymphocytes.*Indications for Piroxicam*1. Rheumatoid arthritis *2. Osteoarthritis *3. Ankylosing spondylitis *4. Acute musculo-skeletal disorders *5. Acute gout *6. Post-operative & post-traumatic pain *7. Primary dysmenorrhea *Interactions for Piroxicam*Anticoagulants: May prolong prothrombin time. *Beta-Blockers: Antihypertensive effect may be impaired. *Cyclosporine: Nephrotoxicity of both agents may be increased. *Lithium: Serum lithium levels may be increased. *Hydantoins: Serum hydantoin levels increase
PIROXIFAR 20mg/ml 3 amp.PIROXICAMPHARCONSAID.Oxicam6.5About Piroxicam*NSAID,Oxicam derivative, Analgesic,antiinflammatory.*Mechanism of Action of Piroxicam*Drug inhibits the biosynthesis and release of prostaglandins by inhibiting cyclooxygenase enzyme in a reversible manner. In this way it reduces the PG (Prostaglandin) concentration in the synovial fluid. It also reduces platelet aggregation (prolong bleeding time), production of IgM rheumatoid factor, chemotaxis of leukocytes and ratio of T-helper to T- suppressor lymphocytes.*Indications for Piroxicam*1. Rheumatoid arthritis *2. Osteoarthritis *3. Ankylosing spondylitis *4. Acute musculo-skeletal disorders *5. Acute gout *6. Post-operative & post-traumatic pain *7. Primary dysmenorrhea *Interactions for Piroxicam*Anticoagulants: May prolong prothrombin time. *Beta-Blockers: Antihypertensive effect may be impaired. *Cyclosporine: Nephrotoxicity of both agents may be increased. *Lithium: Serum lithium levels may be increased. *Hydantoins: Serum hydantoin levels increase
PREDNISOLONE 1% eye drops 5 MLPREDNISOLONEPHARCO13.2About Prednisolone*Systemic synthetic Glucocorticoid, Immunosuppressant.*Mechanism of Action of Prednisolone*The drug exerts it`s pharmacological action by penetrating and binding to cytoplasmic receptor protein and causes a structural change in steroid receptor complex. This structural change allows it`s migration in to the nucleus and then binding to specific sites on the DNA which leads to transcription of specific m-RNA and which ultimately regulates protein synthesis. It exerts more selective glucocorticoid action with little mineralocorticoid actions. *The drug exerts anti-inflammatory and immunosuppressant actions as follows: - 1) Induce lipocortins in macrophages, endothelium, and fibroblasts which inhibits phospholipase A2 and thus decreases the production of Prostaglandins, leukotriens (LT), and platelet activating factor, 2) Causes negative regulation of genes for cytokines in macrophages, endothelial cells and lymphocytes and thus decreases the production of interleukin
PREGVIT-ZINC 24 Caps.VITAMINSPHARCOvitamin14.4About Vitamins*Vitamins are substances that are found in foods we eat. The term vitamin is derived from the words vital and amine, because vitamins are required for life and were originally thought to be amines. All vitamins are not amines. Vitamins are different in their chemistry, but they all are organic nutrients that are necessary in small amounts for normal metabolism and good health. Most vitamins must be provided by the diet or by supplements- only three vitamins (D, K, and the B vitamin biotin) can be manufactured in the body from non dietary sources. Vitamins are not sources of energy as are carbohydrates, fats, and proteins. Instead, vitamins serve as chemical partners for the enzymes involved in the body`s metabolism, cell production, tissue repair, and other vital processes. Vitamins serve crucial functions in almost all bodily processes example immune, hormonal and nervous systems. *In humans there are thirteen vitamins, divided into two groups.
PROCTOPHAR 5 supp.EPHEDRINE HCL -- BENZOCAINE -- ZINC OXIDE -- LIQUID EXTRACT OF HAMAMELISPHARCO5
PROGEST 100mg 24 Caps.PROGESTERONEPHARCO32.5"Indication *For progesterone supplementation or replacement as part of an Assisted Reproductive Technology (ART) treatment for infertile women with progesterone deficiency and for the treatment of secondary amenorrhea. Also used for the reduction of the incidence of endometrial hyperplasia and the attendant risk of endometrial carcinoma in postmenopausal women receiving estrogen replacement therapy, as well as treatment of abnormal uterine bleeding due to hormonal imbalance in the absence of organic pathology such as fibroids or uterine cancer.*Mechanism of action Progesterone shares the pharmacological actions of the progestins. Progesterone binds to the progesterone and estrogen receptors. Target cells include the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Once bound to the receptor, progestins like Progesterone will slow the frequency of release of gonadotropin releasing hormone (GnRH) from the hypothalamus and blunt the pre-ovulatory LH (lu"
PROSTACAP 50mg 24 Caps.PYGEUM AFRICANUM EXTRACTPHARCO18
PROSTALIN 5 rectal supp.HAMAMELIS EXTRACT -- ICHTAMMOL -- POTASSIUM IODIDEPHARCO4.25
PROSTASIN 2mg 20 tab.TERAZOCINPHARCO12"Indication *For the treatment of symptomatic BPH and mild to moderate hypertension.*Mechanism of action In general, a1-adrenergic receptors mediate contraction and hypertrophic growth of smooth muscle cells. a1-Receptors are 7-transmembrane domain receptors coupled to G proteins, Gq/11. Three a1-receptor subtypes, which share approximately 75% homology in their transmembrane domains, have been identified: a1A (chromosome 8), a1B (chromosome 5), and a1D (chromosome 20). Terazosin is the first a1-receptor antagonist to demonstrate selectivity for the a1A-receptor. All three receptor subtypes appear to be involved in maintaining vascular tone. The a1A-receptor maintains basal vascular tone while the a1B-receptor mediates the vasocontrictory effects of exogenous a1-agonists. Activation of a1-receptors activates Gq-proteins, which results in intracellular stimulation of phospholipases C, A2, and"
PROSTASIN 5mg 20 tab.TERAZOCINPHARCO24"Indication *For the treatment of symptomatic BPH and mild to moderate hypertension.*Mechanism of action In general, a1-adrenergic receptors mediate contraction and hypertrophic growth of smooth muscle cells. a1-Receptors are 7-transmembrane domain receptors coupled to G proteins, Gq/11. Three a1-receptor subtypes, which share approximately 75% homology in their transmembrane domains, have been identified: a1A (chromosome 8), a1B (chromosome 5), and a1D (chromosome 20). Terazosin is the first a1-receptor antagonist to demonstrate selectivity for the a1A-receptor. All three receptor subtypes appear to be involved in maintaining vascular tone. The a1A-receptor maintains basal vascular tone while the a1B-receptor mediates the vasocontrictory effects of exogenous a1-agonists. Activation of a1-receptors activates Gq-proteins, which results in intracellular stimulation of phospholipases C, A2, and"
RANI 150mg 6 sachets.RANITIDINEPHARCOPeptic Ulcer.Anti-Histamine.H2 Antagonist9About Ranitidine*A histamine H2-receptor antagonist, Furan derivative, Anti-secretory G.I agent,Anti ulcer.*Mechanism of Action of Ranitidine*Ranitidine is a H2 (Histamine) receptor antagonist. Histamine is the most potent stimulus of acid secretion and acts as the common mediator. H2 receptor is a G-protein coupled receptor. It induces adenylate cyclase which converts ATP to cyclic AMP. This cyclic AMP acts on proton pump and exchange extracellular potassium ion for intracellular hydrogen ion across the parietal cell membrane. Ranitidine reversibly competes with Histamine for binding to H2 receptors on the parietal cells and predominantly inhibits basal acid secretion. *Anaesthetic adjuncts: It is used in patients undergoing prolonged operations, caesarian section,obese patients those are at increased risk of gastric regurgitation and aspiration pneumonia. It raises pH of gastric juice and also reduces its volume and thus chances of regurgitation.
RANI 50mg/2ml 5 Amp. for I.V/IM injectionRANITIDINEPHARCOPeptic Ulcer.Anti-Histamine.H2 Antagonist13.5About Ranitidine*A histamine H2-receptor antagonist, Furan derivative, Anti-secretory G.I agent,Anti ulcer.*Mechanism of Action of Ranitidine*Ranitidine is a H2 (Histamine) receptor antagonist. Histamine is the most potent stimulus of acid secretion and acts as the common mediator. H2 receptor is a G-protein coupled receptor. It induces adenylate cyclase which converts ATP to cyclic AMP. This cyclic AMP acts on proton pump and exchange extracellular potassium ion for intracellular hydrogen ion across the parietal cell membrane. Ranitidine reversibly competes with Histamine for binding to H2 receptors on the parietal cells and predominantly inhibits basal acid secretion. *Anaesthetic adjuncts: It is used in patients undergoing prolonged operations, caesarian section,obese patients those are at increased risk of gastric regurgitation and aspiration pneumonia. It raises pH of gastric juice and also reduces its volume and thus chances of regurgitation.
RANI 75 mg 12 eff. Gr. IN sachetsRANITIDINEPHARCOPeptic Ulcer.Anti-Histamine.H2 Antagonist7.5About Ranitidine*A histamine H2-receptor antagonist, Furan derivative, Anti-secretory G.I agent,Anti ulcer.*Mechanism of Action of Ranitidine*Ranitidine is a H2 (Histamine) receptor antagonist. Histamine is the most potent stimulus of acid secretion and acts as the common mediator. H2 receptor is a G-protein coupled receptor. It induces adenylate cyclase which converts ATP to cyclic AMP. This cyclic AMP acts on proton pump and exchange extracellular potassium ion for intracellular hydrogen ion across the parietal cell membrane. Ranitidine reversibly competes with Histamine for binding to H2 receptors on the parietal cells and predominantly inhibits basal acid secretion. *Anaesthetic adjuncts: It is used in patients undergoing prolonged operations, caesarian section,obese patients those are at increased risk of gastric regurgitation and aspiration pneumonia. It raises pH of gastric juice and also reduces its volume and thus chances of regurgitation.
RECARDOPRIL 10mg tabs.RAMIPRILPHARCOAnti-hypertensive.ACE19.2About Ramipril*Angiotensin - converting enzyme inhibitor, Antihypertensive.*Mechanism of Action of Ramipril*It is a prodrug and converted in to active Ramiprilat- which is an angiotensin converting enzyme inhibitor prevents the conversion of angiotensin-1 to angiotensin-2 and abolishes the pressor actions of angiotensin. It decreases aldosterone secretion, sodium and water retention, and total peripheral resistance, leads to fall in BP. The arterioles dilate and the compliance of larger arteries is increased. Both systolic and diastolic BP is lowered. The drug does not compromise renal, cerebral, and coronary blood flow. The drug also increases plasma kinin levels and potentiate the hypotensive action of exogenously administered bradykinin. It is used for treatment of systolic heart failure, because it improves symptoms, decrease mortality and reduce ventricular hypertrophy. It reduces both preload and after load and thus increasing cardiac out put in patients with heart failure.
RECARDOPRIL 2.5mg 10tab.RAMIPRILPHARCOAnti-hypertensive.ACE10About Ramipril*Angiotensin - converting enzyme inhibitor, Antihypertensive.*Mechanism of Action of Ramipril*It is a prodrug and converted in to active Ramiprilat- which is an angiotensin converting enzyme inhibitor prevents the conversion of angiotensin-1 to angiotensin-2 and abolishes the pressor actions of angiotensin. It decreases aldosterone secretion, sodium and water retention, and total peripheral resistance, leads to fall in BP. The arterioles dilate and the compliance of larger arteries is increased. Both systolic and diastolic BP is lowered. The drug does not compromise renal, cerebral, and coronary blood flow. The drug also increases plasma kinin levels and potentiate the hypotensive action of exogenously administered bradykinin. It is used for treatment of systolic heart failure, because it improves symptoms, decrease mortality and reduce ventricular hypertrophy. It reduces both preload and after load and thus increasing cardiac out put in patients with heart failure.
RECARDOPRIL 5mg 10tab.RAMIPRILPHARCOAnti-hypertensive.ACE12.3About Ramipril*Angiotensin - converting enzyme inhibitor, Antihypertensive.*Mechanism of Action of Ramipril*It is a prodrug and converted in to active Ramiprilat- which is an angiotensin converting enzyme inhibitor prevents the conversion of angiotensin-1 to angiotensin-2 and abolishes the pressor actions of angiotensin. It decreases aldosterone secretion, sodium and water retention, and total peripheral resistance, leads to fall in BP. The arterioles dilate and the compliance of larger arteries is increased. Both systolic and diastolic BP is lowered. The drug does not compromise renal, cerebral, and coronary blood flow. The drug also increases plasma kinin levels and potentiate the hypotensive action of exogenously administered bradykinin. It is used for treatment of systolic heart failure, because it improves symptoms, decrease mortality and reduce ventricular hypertrophy. It reduces both preload and after load and thus increasing cardiac out put in patients with heart failure.
RECARDOPRIL-D 5/25MG 14 tab.HYDROCHLOROTHIAZIDE -- RAMIPRILPHARCOAnti-hypertensive.Combined ACE with diuretic27.6"This combination product contains two active ingredients: ramipril and hydrochlorothiazide. Ramipril belongs to the class of medications called ACE inhibitors. It works by relaxing blood vessels and by making the heart pump more efficiently. Hydrochlorothiazide belongs to the class of medications known as diuretics or ""water pills"" and helps control blood pressure by getting rid of excess salt and water.**Ramipril - hydrochlorothiazide is used to treat high blood pressure. This combination medication is prescribed when your doctor feels it is appropriate for you to be taking both medications and you have taken ramipril and hydrochlorothiazide as separate medications without any problems. It may take 2 to 4 weeks to see the full effects of this medication."
RESPIRIN 150mg/ml oral dropsHEPTAMINOLPHARCOOrthostatic hypotension5.25Description of Heptaminol*Heptaminol: An amino alcohol that has been used as a myocardial stimulant and vasodilator and to relieve bronchospasm. Its most common therapeutic use is in orthostatic hypotension. The mechanism of heptaminol s therapeutic actions is not well understood although it has been suggested to affect catecholamine release or calcium metabolism.
RIFAM 100MG/5ML 60ml susp.RIFAMPICINPHARCO7About Rifampicin*Rifamycin derivative, Antituberculosis antibiotic.*Mechanism of Action of Rifampicin*Rifampicin is primarily bactericidal and has some bacteriostatic properties also. It acts by inhibiting DNA dependent RNA polymerase and thus stopping the expression of bacterial genes.M.tuberculosis requires DNA dependent RNA polymerase enzyme for the synthesis of RNA and protein. Without this enzyme bacteria cannot reproduce and they die. *Indications for Rifampicin*1. Leprosy *2. Tuberculosis *3. Prophylaxis of meningococcal carriers *4. Prophylaxis of H. influenzae *Interactions for Rifampicin*Rifampicin by inducing the hepatic microsomal enzymes may reduce the efficacy of the following drugs: Acetaminophen, oral anticoagulants, barbiturates, benzodiazepines, chloramphenicol, clofibrate. Oral contraceptives, corticosteroids, cyclosporine, digitoxin, disopyramide, beta blockers oestrogens, hydantoins, mexiletine, quinidine, sulfones, sulphonylureas, theophylline, verapamil
RINOSIN nasal drops 10 MLCHLORPHENIRAMINE -- NAPHAZOLINEPHARCOCorneal vascularity.Antihistamine Combined With alpha 1 agonist3.5INDICATIONS**- Rhinitis (acute, allergic), sinusitis-*- Nasal hemorrhage (as vasoconstrictor) to stop and alleviate conduction of rhinoscopy-*- Hay fever-*- Conjunctivitis (allergic, chronic)-*- Asthenopic disorders (accommodation disturbance in case of enlarged visual activity)*- Spring conjunctivitis (in combined therapy).**CONTRAINDICATIONS*- Rased sensitivity towards any drugï؟½s component.*- Arterial hypertension-*- Tachycardia-*- Hyperthyroidism-*- Evident atherosclerosis-*- Angle-closure glaucoma-*- Parallel intake with MAO inhibitors, and within 14 days after their cancellation.*- Nozeylin is contraindicated to children till the age of 6.**DOSAGE AND ADMINISTRATION**Eye drops:*To adults and children at the age of 6 and elder the recommended dose of the drug is 1-2 drops in conjunctival sac of effected eye (or both eyes) to 4 times a day.*Nose drops:*To adults and children at the age of 6 and elder the recommended dose of the drug is 1-2 drops in every na*
RINOSIN nasal gel 5 GMCHLORPHENIRAMINE -- NAPHAZOLINEPHARCOCorneal vascularity.Antihistamine Combined With alpha 1 agonist4INDICATIONS**- Rhinitis (acute, allergic), sinusitis-*- Nasal hemorrhage (as vasoconstrictor) to stop and alleviate conduction of rhinoscopy-*- Hay fever-*- Conjunctivitis (allergic, chronic)-*- Asthenopic disorders (accommodation disturbance in case of enlarged visual activity)*- Spring conjunctivitis (in combined therapy).**CONTRAINDICATIONS*- Rased sensitivity towards any drugï؟½s component.*- Arterial hypertension-*- Tachycardia-*- Hyperthyroidism-*- Evident atherosclerosis-*- Angle-closure glaucoma-*- Parallel intake with MAO inhibitors, and within 14 days after their cancellation.*- Nozeylin is contraindicated to children till the age of 6.**DOSAGE AND ADMINISTRATION**Eye drops:*To adults and children at the age of 6 and elder the recommended dose of the drug is 1-2 drops in conjunctival sac of effected eye (or both eyes) to 4 times a day.*Nose drops:*To adults and children at the age of 6 and elder the recommended dose of the drug is 1-2 drops in every na*
ROYAL JELLY 1000MG 12 CAPSROYAL JELLYPHARCO45
ROYAL JELLY 600MG 12 CAPS.ROYAL JELLYPHARCO36
RUTIN-C 24 Caps.RUTIN -- VITAMIN CPHARCO3.75About Rutin*Glycoside between the flavonol quercetin and the disaccharide rutinose. Rutin may have antioxidant, anti-inflammatory, anticarcinogenic, antithrombotic,cytoprotective and vasoprotective activities.*Mechanism of Action of Rutin*1.Rutin inhibits platelet aggregation, as well as decreasing capillary permeability, making the blood thinner and improving circulation. *2.Rutin shows anti-inflammatory activity in some animal and in vitro models. *3.Rutin inhibits aldose reductase activit. Aldose reductase is an enzyme normally present in the eye and elsewhere in the body. It helps change glucose into the sugar alcohol sorbitol. *4.Rutin also strengthens the capillaries, and, therefore, can reduce the symptoms of haemophilia. It also may help to prevent a common, unpleasant-looking, venous edema of the legs- however, a double-blind clinical study on the effect of buckwheat tea containing rutin did not show a significant effect above placebo. *
SCHIZONEX 100 mg 50 tab.CLOZAPINEPHARCOpsychiatric.Antipsychotics76About Clozapine*Dibenzodiazepine derivative , Atypical antipsychotic, Tranquilizer, anti-psychotic.*Mechanism of Action of Clozapine*Clozapine binds to dopamine receptors. It has more affinity towards D4 receptor than other Dopamine receptors i.e.D1, D2, D3 &D5 receptors. It exerts its antipsychotic activity by blocking the dopamine projections in the limbic system. It acts as a competitive Dopamine antagonist. Clozapine also produces alpha adrenergic blocking activity, anti-serotonin activity and anticholinergic activity. It also produces moderately potent anticholinergic but paradoxically induce salivation and H1 blocking activity.**Interactions for Clozapine*Anticholinergics: Anticholinergic effects may be potentiated. *Antihypertensives: Hypotensive effects may be potentiated. *CNS drugs: Caution is advised with concomitant use. *Agents that suppress bone marrow function: Avoid concomitant use.
SCHIZONEX 25 mg 50 tab.CLOZAPINEPHARCOpsychiatric.Antipsychotics26About Clozapine*Dibenzodiazepine derivative , Atypical antipsychotic, Tranquilizer, anti-psychotic.*Mechanism of Action of Clozapine*Clozapine binds to dopamine receptors. It has more affinity towards D4 receptor than other Dopamine receptors i.e.D1, D2, D3 &D5 receptors. It exerts its antipsychotic activity by blocking the dopamine projections in the limbic system. It acts as a competitive Dopamine antagonist. Clozapine also produces alpha adrenergic blocking activity, anti-serotonin activity and anticholinergic activity. It also produces moderately potent anticholinergic but paradoxically induce salivation and H1 blocking activity.**Interactions for Clozapine*Anticholinergics: Anticholinergic effects may be potentiated. *Antihypertensives: Hypotensive effects may be potentiated. *CNS drugs: Caution is advised with concomitant use. *Agents that suppress bone marrow function: Avoid concomitant use.
SERTRAL 50mg 10 tab.SERTRALINEPHARCOpsychiatric.Antidepressants21.6About Sertraline*Selective Serotonin Reuptake Inhibitor (SSRI), Antidepressant, Antidepressant*Mechanism of Action of Sertraline*Sertraline blocks the re-uptake of neurotransmitter Serotonin from the synapse in to the presynaptic nerve terminal in the CNS. This will prolong the action of Serotonin (5HT) and it is useful in the treatment of depression.*Side Effects of Sertraline*1. Insomnia *2. Nausea *3. Diarrhoea *4. Headache *5. Fatigue *6. Dizziness *7. Tremor *8. Somnolence *9. Dry mouth *10. Anorexia *11. Impotence *12. Increased sweating *13. Constipation *14. Dyspepsia *15. Agitation *16. Malaise *17. Abdominal pain
SIMVA-EZE 10/10 mg 7tab.EZETIMIBE -- SIMVASTATINPHARCOAntihyperlipidemic.Cholesterol Absorption Inhibitors.Combined with statin15.5About Ezetimibe*Cholesterol Absorption Inhibitor, 2-Azetidinone derivative, Hypolipidemic agent.*Mechanism of Action of Ezetimibe*It reduces the absorption of cholesterol from the intestine by localising at the brush border of the small intestine, where it inhibits the absorption of cholesterol from the diet. Specifically, it appears to bind to the Niemann-Pick C1-Like 1 (NPC1L1) protein on the gastrointestinal tract epithelium, a critical mediator of cholesterol absorption. This decreased cholesterol absorption leads to an increase in LDL-cholesterol uptake into cells, thus decreasing levels in the blood plasma.*Indications for Ezetimibe*1. Adjunct to dietary measures and statin in primary and homozygous familial hypercholesterolaemia *2. Adjunct to dietary measures in homozygous familial sitosterolaemia *Interactions for Ezetimibe*Cyclosporin: Plasma concentraction of ezetimibe increased. Lipid-regulating drugs: Avoid concomitant use with fibrates.
SIMVA-EZE 20/10mg 7tab.EZETIMIBE -- SIMVASTATINPHARCOAntihyperlipidemic.Cholesterol Absorption Inhibitors.Combined with statin21.6About Ezetimibe*Cholesterol Absorption Inhibitor, 2-Azetidinone derivative, Hypolipidemic agent.*Mechanism of Action of Ezetimibe*It reduces the absorption of cholesterol from the intestine by localising at the brush border of the small intestine, where it inhibits the absorption of cholesterol from the diet. Specifically, it appears to bind to the Niemann-Pick C1-Like 1 (NPC1L1) protein on the gastrointestinal tract epithelium, a critical mediator of cholesterol absorption. This decreased cholesterol absorption leads to an increase in LDL-cholesterol uptake into cells, thus decreasing levels in the blood plasma.*Indications for Ezetimibe*1. Adjunct to dietary measures and statin in primary and homozygous familial hypercholesterolaemia *2. Adjunct to dietary measures in homozygous familial sitosterolaemia *Interactions for Ezetimibe*Cyclosporin: Plasma concentraction of ezetimibe increased. Lipid-regulating drugs: Avoid concomitant use with fibrates.
SIMVA-EZE 40/10mg 7tab.EZETIMIBE -- SIMVASTATINPHARCOAntihyperlipidemic.Cholesterol Absorption Inhibitors.Combined with statin23.5About Ezetimibe*Cholesterol Absorption Inhibitor, 2-Azetidinone derivative, Hypolipidemic agent.*Mechanism of Action of Ezetimibe*It reduces the absorption of cholesterol from the intestine by localising at the brush border of the small intestine, where it inhibits the absorption of cholesterol from the diet. Specifically, it appears to bind to the Niemann-Pick C1-Like 1 (NPC1L1) protein on the gastrointestinal tract epithelium, a critical mediator of cholesterol absorption. This decreased cholesterol absorption leads to an increase in LDL-cholesterol uptake into cells, thus decreasing levels in the blood plasma.*Indications for Ezetimibe*1. Adjunct to dietary measures and statin in primary and homozygous familial hypercholesterolaemia *2. Adjunct to dietary measures in homozygous familial sitosterolaemia *Interactions for Ezetimibe*Cyclosporin: Plasma concentraction of ezetimibe increased. Lipid-regulating drugs: Avoid concomitant use with fibrates.
SINE UP 20 tab.CHLORPHENIRAMINE -- PARACETAMOL(ACETAMINOPHEN) -- PHENYLEPHRINEPHARCO6.5
SINE UP SYRUP 120 MLCHLORPHENIRAMINE -- PHENYLEPHRINEPHARCO6.75"Description *A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma.*Indication For the treatment of rhinitis, urticaria, allergy, common cold, asthma and hay fever.*Pharmacodynamics In allergic reactions an allergen interacts with and cross-links surface IgE antibodies on mast cells and basophils. Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell-degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. Once released, histamine can react with local or widespread tissues through histamine receptors. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Chlorpheniramine, is a histamine H1 antagonist (or more correctly, an inverse histamine agonist) of the alkylamine class."
SPASMIN 5 paed.supp.HEXAHYDRO-ADIPHENINE -- PROPYPHENAZONEPHARCO3.05
SPASMO-DIGESTIN 30 tab.DICYCLOMINE -- PAPAIN -- SANZYME 3500 -- SIMETHICONE -- SODIUM DEHYDROCHOLATEPHARCO22.5About Dicyclomine*Anticholinergic ,Antimuscarinic, Antispasmodic and in urinary incontinence.*Mechanism of Action of Dicyclomine*Dicyclomine is an anticholinergic drug. It exerts its action by inhibiting muscarinic (((cholinergic))) receptors on smooth muscles and prevents the effect of Acetylcholine. Inhibition of Acetylcholine produces relaxation of smooth muscles of gastrointestinal tract and genitourinary tract and reduces the painful spasm and cramp. It inhibits gastrointestinal propulsive motility and reduces gastric acid secretion. It also has a direct relaxant effect on smooth muscle. It readily crosses the blood brain barrier and produces CNS effects.
SULBIN 1.5gm vialAMPICILLIN -- SULBACTAMPHARCOPenicillins.Penicillin with B-lactamase inhbitor20.75Other Indications & Uses*Beta-lactamase-producing: S. aureus, E. coli, Klebsiella spp, P. mirabilis, Bacteroides fragilis, Enterobacter spp, Acinetobacter calcoaceticus*Systemic Adverse Reactions*systemic reactions reported in less than 1% of the patients were: itching, nausea, vomiting, candidiasis, fatigue, malaise, headache, chest pain, flatulence, abdominal distension, glossitis, urine retention, dysuria, edema, facial swelling, erythema, chills, tightness in throat, substernal pain, epistaxis and mucosal bleeding.*
SULBIN 375mg vialAMPICILLIN -- SULBACTAMPHARCOPenicillins.Penicillin with B-lactamase inhbitor10.25Other Indications & Uses*Beta-lactamase-producing: S. aureus, E. coli, Klebsiella spp, P. mirabilis, Bacteroides fragilis, Enterobacter spp, Acinetobacter calcoaceticus*Systemic Adverse Reactions*systemic reactions reported in less than 1% of the patients were: itching, nausea, vomiting, candidiasis, fatigue, malaise, headache, chest pain, flatulence, abdominal distension, glossitis, urine retention, dysuria, edema, facial swelling, erythema, chills, tightness in throat, substernal pain, epistaxis and mucosal bleeding.*
SULBIN 750mg vialAMPICILLIN -- SULBACTAMPHARCOPenicillins.Penicillin with B-lactamase inhbitor14.75Other Indications & Uses*Beta-lactamase-producing: S. aureus, E. coli, Klebsiella spp, P. mirabilis, Bacteroides fragilis, Enterobacter spp, Acinetobacter calcoaceticus*Systemic Adverse Reactions*systemic reactions reported in less than 1% of the patients were: itching, nausea, vomiting, candidiasis, fatigue, malaise, headache, chest pain, flatulence, abdominal distension, glossitis, urine retention, dysuria, edema, facial swelling, erythema, chills, tightness in throat, substernal pain, epistaxis and mucosal bleeding.*
TAURAL 50mg/5ml I.V.amp.RANITIDINEPHARCOPeptic Ulcer.Anti-Histamine.H2 Antagonist7About Ranitidine*A histamine H2-receptor antagonist, Furan derivative, Anti-secretory G.I agent,Anti ulcer.*Mechanism of Action of Ranitidine*Ranitidine is a H2 (Histamine) receptor antagonist. Histamine is the most potent stimulus of acid secretion and acts as the common mediator. H2 receptor is a G-protein coupled receptor. It induces adenylate cyclase which converts ATP to cyclic AMP. This cyclic AMP acts on proton pump and exchange extracellular potassium ion for intracellular hydrogen ion across the parietal cell membrane. Ranitidine reversibly competes with Histamine for binding to H2 receptors on the parietal cells and predominantly inhibits basal acid secretion. *Anaesthetic adjuncts: It is used in patients undergoing prolonged operations, caesarian section,obese patients those are at increased risk of gastric regurgitation and aspiration pneumonia. It raises pH of gastric juice and also reduces its volume and thus chances of regurgitation.
THEOFAR 100mg S.R.caps.THEOPHYLLINEPHARCOBronchodilator.Phosphodiesterase Inhibitors3.5About Theophylline*Bronchodilator, a methylxanthine derivative, Anti asthma, in COPD.*Mechanism of Action of Theophylline*It inhibit phosphodiesterase enzyme which degrades cyclic nucleotides intracellularly and it results the cyclic AMP accumulation in the cell. This cause bronchodialatation, cardiac stimulation and vasodilatation. This drug release calcium from sarcoplasmic reticulam, especially in cardiac muscles and results increased cardiac muscle contraction. This drug also blocks adenosine receptors (adenosine acts as a local mediator in CNS & CVS and other organs- which contracts smooth muscles, especially in bronchi, blood vessels etc). This results bronchodialatation and vasodialatation.*Indications for Theophylline*1. Asthma *2. Chronic obstructive pulmonary disease *3. Chronic bronchitis *4. Emphysema *5. It can be used in premature infants who stop breathing *
THEOFAR 200mg S.R.caps.THEOPHYLLINEPHARCOBronchodilator.Phosphodiesterase Inhibitors4.4About Theophylline*Bronchodilator, a methylxanthine derivative, Anti asthma, in COPD.*Mechanism of Action of Theophylline*It inhibit phosphodiesterase enzyme which degrades cyclic nucleotides intracellularly and it results the cyclic AMP accumulation in the cell. This cause bronchodialatation, cardiac stimulation and vasodilatation. This drug release calcium from sarcoplasmic reticulam, especially in cardiac muscles and results increased cardiac muscle contraction. This drug also blocks adenosine receptors (adenosine acts as a local mediator in CNS & CVS and other organs- which contracts smooth muscles, especially in bronchi, blood vessels etc). This results bronchodialatation and vasodialatation.*Indications for Theophylline*1. Asthma *2. Chronic obstructive pulmonary disease *3. Chronic bronchitis *4. Emphysema *5. It can be used in premature infants who stop breathing *
THEOFAR 300mg S.R.caps.THEOPHYLLINEPHARCOBronchodilator.Phosphodiesterase Inhibitors4.8About Theophylline*Bronchodilator, a methylxanthine derivative, Anti asthma, in COPD.*Mechanism of Action of Theophylline*It inhibit phosphodiesterase enzyme which degrades cyclic nucleotides intracellularly and it results the cyclic AMP accumulation in the cell. This cause bronchodialatation, cardiac stimulation and vasodilatation. This drug release calcium from sarcoplasmic reticulam, especially in cardiac muscles and results increased cardiac muscle contraction. This drug also blocks adenosine receptors (adenosine acts as a local mediator in CNS & CVS and other organs- which contracts smooth muscles, especially in bronchi, blood vessels etc). This results bronchodialatation and vasodialatation.*Indications for Theophylline*1. Asthma *2. Chronic obstructive pulmonary disease *3. Chronic bronchitis *4. Emphysema *5. It can be used in premature infants who stop breathing *
TOPICORT 0.1% cream 20 GMTRIAMCINOLONE ACETONIDEPHARCOAnti-inflammatory.glucocorticoid.6About Triamcinolone acetonide*A synthetic glucocorticoid, Topical anti-inflammatory(steroidal).*Mechanism of Action of Triamcinolone acetonide*The drug exerts it`s pharmacological action by penetrating and binding to cytoplasmic receptor protein and causes a structural change in steroid receptor complex. This structural change allows it`s migration in to the nucleus and then binding to specific sites on the DNA which leads to transcription of specific m-RNA and which ultimately regulates protein synthesis. It exerts more selective glucocorticoid action. It stimulates the enzymes needed to decrease the inflammatory response. *The drug exerts anti-inflammatory and immunosuppressant actions as follows: - 1) Induce lipocortins in macrophages, endothelium, and fibroblasts which inhibits phospholipase A2 and thus decreases the production of Prostaglandins, leukotriens (LT), and platelet activating factor, 2) Causes negative regulation of genes for cytokines in macrophages,
ULSTOP 20mg 14 hard gelatin Caps.OMEPRAZOLEPHARCOPeptic Ulcer.proton pump inhibitor42.4About Omeprazole*Proton Pump Inhibitor, Substituted Benzimidazole, Anti-secretory,antiulcer.*Mechanism of Action of Omeprazole*Omeprazole is a proton pump inhibitor and it is a prodrug. After administration it diffuses in to the parietal cell of the stomach and accumulates in the secretory canaliculi. In the acidic medium Omeprazole is converted to sulfenamide. This sulfenamide covalently interacts with sulfhydryl (SH) group in the proton pump *(H -- K -- ATPase) and inhibits the exchange of extracellular K -- for intracellular H -- ion. Omeprazole irreversibly inhibits proton pumps activity and decreases gastric acid secretion.
URICOL 6 eff. gr. IN SACHETSHEXAMINE -- KHELLIN -- PIPERAZINEPHARCOUrinary.Analgesic.Antiseptic4PROPERTIES:*It is a complementary combination of three active ingredients which ensures superior efficacy in the treatï؟½ ment of urinary tract infections and enhances urinary excretion of uric acid. Hexamine is a urinary tract antiseptic, slowly hydrolyzed to formaldehyde which possesses antiï؟½ bacterial activity against most common urinary tract pathogens. Khellin, a natural ingredient acts directly as a relaxant of the urinary tract smooth muscles thus relieving colics usually associatedwith urinary disorders. Piperazine adds to the benefits of RENAL-S by dissolving uric acid and urate crystals thus preventing their deposition in the urinary tract, ensuring the effectiveness of RENAL-S in treatment of urate calculi.*INDICATIONS:*1-Urinary tract infections: pyelitis, cystitis, urethritis and pyelonephritis.*2-Adjuvant in case of recurrent urate calculi.*3-Spasms of urinary tract.*4-Discomfort caused by hypermotiiity resulting from inflammation due to urinary tract infections.
URICOL PLUS 12 sachetsCOLCHICINE -- KHELLIN -- PIPERAZINE CITRATEPHARCOAntigout.Analgesic6Mechanism of Action of Colchicine*It inhibits microtubule polymerization by binding to tubulin, one of the main constituents of microtubules. This tubulin is essential to mitosis, and therefore it inhibits the development of spindles as the nuclei are dividing. These results the death of rapidly proliferating cells. Colchicines in gout reduce lactic acid production by leukocytes, which results in a decrease in uric acid deposition, and it also reduce phagocytosis, with abatement of the inflammatory response.
URICONTROL 2mg 10 tab.TOLTERODINE L TARTARATEPHARCOUrinary incontinence.Antispasmodics.Muscarinic Antagonists14.4About Tolterodine Tartarate*Anticholinergic ( antimuscarinic), Treat urinary incontinence.*Mechanism of Action of Tolterodine Tartarate*Tolterodine tartrate is a specific muscarinic receptor (M3 receptor) antagonist. It blocks muscarinic receptors which can be found on the muscle cells of the bladder wall. It prevents the action of acetyl choline on these receptors. Acetylcholine acting on these receptors causes the muscle in the bladder wall to contract, and the bladder to empty. By preventing this, Tolterodine helps the muscle in the bladder wall to relax. This reduces unstable, involuntary contractions of the bladder, and thereby increases the capacity of the bladder to hold urine. This in turn reduces the need to pass urine. *Stimulation of muscarinic receptors causes the bladder to contract and empty. Tolterodine relax the involuntary muscle in the wall of the bladder.
URICONTROL SR 4mg 12 CAPS.TOLTERODINE L TARTARATEPHARCOUrinary incontinence.Antispasmodics.Muscarinic Antagonists17.5About Tolterodine Tartarate*Anticholinergic ( antimuscarinic), Treat urinary incontinence.*Mechanism of Action of Tolterodine Tartarate*Tolterodine tartrate is a specific muscarinic receptor (M3 receptor) antagonist. It blocks muscarinic receptors which can be found on the muscle cells of the bladder wall. It prevents the action of acetyl choline on these receptors. Acetylcholine acting on these receptors causes the muscle in the bladder wall to contract, and the bladder to empty. By preventing this, Tolterodine helps the muscle in the bladder wall to relax. This reduces unstable, involuntary contractions of the bladder, and thereby increases the capacity of the bladder to hold urine. This in turn reduces the need to pass urine. *Stimulation of muscarinic receptors causes the bladder to contract and empty. Tolterodine relax the involuntary muscle in the wall of the bladder.
URINEX 24 Caps.ALPHA PINENE -- ANETHOL -- BETA PINENE -- BORNEOL -- CAMPHENE -- CINEOL -- FENCHONELPHARCO9The chemical substance alpha-pinene is a component of many essential oils and has anti-inflammatory and antimicrobial properties.
V2 - 24 Caps.VITAMINSPHARCOvitamin7About Vitamins*Vitamins are substances that are found in foods we eat. The term vitamin is derived from the words vital and amine, because vitamins are required for life and were originally thought to be amines. All vitamins are not amines. Vitamins are different in their chemistry, but they all are organic nutrients that are necessary in small amounts for normal metabolism and good health. Most vitamins must be provided by the diet or by supplements- only three vitamins (D, K, and the B vitamin biotin) can be manufactured in the body from non dietary sources. Vitamins are not sources of energy as are carbohydrates, fats, and proteins. Instead, vitamins serve as chemical partners for the enzymes involved in the body`s metabolism, cell production, tissue repair, and other vital processes. Vitamins serve crucial functions in almost all bodily processes example immune, hormonal and nervous systems. *In humans there are thirteen vitamins, divided into two groups.
V2 PLUS 24 Caps.VITAMINSPHARCOvitamin9About Vitamins*Vitamins are substances that are found in foods we eat. The term vitamin is derived from the words vital and amine, because vitamins are required for life and were originally thought to be amines. All vitamins are not amines. Vitamins are different in their chemistry, but they all are organic nutrients that are necessary in small amounts for normal metabolism and good health. Most vitamins must be provided by the diet or by supplements- only three vitamins (D, K, and the B vitamin biotin) can be manufactured in the body from non dietary sources. Vitamins are not sources of energy as are carbohydrates, fats, and proteins. Instead, vitamins serve as chemical partners for the enzymes involved in the body`s metabolism, cell production, tissue repair, and other vital processes. Vitamins serve crucial functions in almost all bodily processes example immune, hormonal and nervous systems. *In humans there are thirteen vitamins, divided into two groups.
VASONORM 10mg 10 tab.AMLODIPINEPHARCOAntihypertensive.selective calcium channel blocker14.4About Amlodipine*Calcium Channel Blocker, Anti hypertensive,anti angina.**Mechanism of Action of Amlodipine*Amlodipine is a second generation dihydropyridine Ca channel blocker. It exerts it`s antihypertensive, antianginal actions through blocking the influx of Ca ions through voltage gated L-type Ca channels to the peripheral vascular smooth muscle cells, Coronary smooth muscle cells and to the myocardial cells. Thus causes dilatation of vascular endothelium, decrease peripheral resistance, & reduce myocardial oxygen demand .It markedly relax arterioles and milder effects on veins. They do not compromise haemodynamics and cerebral and renal perfusion.**Indications for Amlodipine*1.Hypertension *2.Prinzmetal`s angina *3.Stable angina
VASONORM 5mg 10 tab.AMLODIPINEPHARCOAntihypertensive.selective calcium channel blocker10.5About Amlodipine*Calcium Channel Blocker, Anti hypertensive,anti angina.**Mechanism of Action of Amlodipine*Amlodipine is a second generation dihydropyridine Ca channel blocker. It exerts it`s antihypertensive, antianginal actions through blocking the influx of Ca ions through voltage gated L-type Ca channels to the peripheral vascular smooth muscle cells, Coronary smooth muscle cells and to the myocardial cells. Thus causes dilatation of vascular endothelium, decrease peripheral resistance, & reduce myocardial oxygen demand .It markedly relax arterioles and milder effects on veins. They do not compromise haemodynamics and cerebral and renal perfusion.**Indications for Amlodipine*1.Hypertension *2.Prinzmetal`s angina *3.Stable angina
VASTOR 20mg 20 F.C. Tab.TRIMETAZIDINEPHARCOAnti-Ischemic9About Trimetazidine*Cytoprotective,vasodilator, Anti-ischemic (anti-anginal) agent.*Mechanism of Action of Trimetazidine*It is a cytoprotective drug which reduces anginal attacks and improves exercise tolerance by nonhaemodynamic mechanisms. It improves cellular tolerance to ischaemia by: - 1) Inhibiting mitochondrial long chain 3-ketoacyl-CoA-thiolase- a key enzyme in fatty acid oxidation and there by reducing fatty acid metabolism and increasing glucose metabolism in myocardium. 2) Limiting intracellular acidosis and sodium and calcium accumulation during ischaemia. 3) Protecting against O* free radical induced membrane damage
VENTOPHYL 100mg S.R. 16 caps.THEOPHYLLINEPHARCOBronchodilator.Phosphodiesterase Inhibitors5About Theophylline*Bronchodilator, a methylxanthine derivative, Anti asthma, in COPD.*Mechanism of Action of Theophylline*It inhibit phosphodiesterase enzyme which degrades cyclic nucleotides intracellularly and it results the cyclic AMP accumulation in the cell. This cause bronchodialatation, cardiac stimulation and vasodilatation. This drug release calcium from sarcoplasmic reticulam, especially in cardiac muscles and results increased cardiac muscle contraction. This drug also blocks adenosine receptors (adenosine acts as a local mediator in CNS & CVS and other organs- which contracts smooth muscles, especially in bronchi, blood vessels etc). This results bronchodialatation and vasodialatation.*Indications for Theophylline*1. Asthma *2. Chronic obstructive pulmonary disease *3. Chronic bronchitis *4. Emphysema *5. It can be used in premature infants who stop breathing *
VENTOPHYL 200mg S.R. 16 caps.THEOPHYLLINEPHARCOBronchodilator.Phosphodiesterase Inhibitors6.7About Theophylline*Bronchodilator, a methylxanthine derivative, Anti asthma, in COPD.*Mechanism of Action of Theophylline*It inhibit phosphodiesterase enzyme which degrades cyclic nucleotides intracellularly and it results the cyclic AMP accumulation in the cell. This cause bronchodialatation, cardiac stimulation and vasodilatation. This drug release calcium from sarcoplasmic reticulam, especially in cardiac muscles and results increased cardiac muscle contraction. This drug also blocks adenosine receptors (adenosine acts as a local mediator in CNS & CVS and other organs- which contracts smooth muscles, especially in bronchi, blood vessels etc). This results bronchodialatation and vasodialatation.*Indications for Theophylline*1. Asthma *2. Chronic obstructive pulmonary disease *3. Chronic bronchitis *4. Emphysema *5. It can be used in premature infants who stop breathing *
VINCABRAL 30mg 50 Caps.VINCAMINEPHARCO34.75
VITAMIN A & E soft gelatin 24Caps.VITAMIN A -- VITAMIN EPHARCO4About Vitamin A*Fat-soluble vitamin, Treatment of vitamin A deficiency.*Mechanism of Action of Vitamin A*Vitamin A is required for a variety of physiological functions in the body such as: - 1).Proper functioning of retina and formation of pigment Rhodopsin during dark adaptation. 2).promotes differentiation and maintains structural integrity of epithelia over the body and also retard the malignancies of epithelial structures.3).Promotes mucous secretion. 4).Inhibits keratinization, 5). Maintains proper bone growth, 6).Maintenance of spermatogenesis, 7).Supports foetal development, 8).Improves resistance to infection. It is required for proper antibody response, normal lymphocyte proliferation and killer cell function.
VITAMIN A 50.000I.u. soft gelatin 24Caps.VITAMIN APHARCO3.8About Vitamin A*Fat-soluble vitamin, Treatment of vitamin A deficiency.*Mechanism of Action of Vitamin A*Vitamin A is required for a variety of physiological functions in the body such as: - 1).Proper functioning of retina and formation of pigment Rhodopsin during dark adaptation. 2).promotes differentiation and maintains structural integrity of epithelia over the body and also retard the malignancies of epithelial structures.3).Promotes mucous secretion. 4).Inhibits keratinization, 5). Maintains proper bone growth, 6).Maintenance of spermatogenesis, 7).Supports foetal development, 8).Improves resistance to infection. It is required for proper antibody response, normal lymphocyte proliferation and killer cell function.*Indications for Vitamin A*1. Vitamin A deficiency *2. Xerophthalmia *3. Acne *4. Ichthyosis *5. Bitot`s spots *6. Night blindness
VITAMIN E 1000mg 24 Caps.VITAMIN EPHARCO36Mechanism of Action of Vitamin E*Vitamin E acts as an antioxidant and protecting unsaturated lipids in the cell membrane, coenzyme Q, vitamin A, vitamin C etc. from free radical oxidation damage and generation of toxic peroxidation products. It also decreases platelet aggregation.*Indications for Vitamin E*1. Vitamin E deficiency *2. Intermittent claudication *3. Nocturnal muscle cramps *4. Coronary artery disease *5. Fibrocystic breast disease *6. Cystic fibrosis *7. In premature infants exposed to high concentration of oxygen *8. As antioxidant ***Interactions for Vitamin E*Oral anticoagulants : Hypoprothrombinemic effect may be increased with possibility of bleeding.
VITAMIN E 100mg 24 soft gelatin Caps.VITAMIN EPHARCO5.75Mechanism of Action of Vitamin E*Vitamin E acts as an antioxidant and protecting unsaturated lipids in the cell membrane, coenzyme Q, vitamin A, vitamin C etc. from free radical oxidation damage and generation of toxic peroxidation products. It also decreases platelet aggregation.*Indications for Vitamin E*1. Vitamin E deficiency *2. Intermittent claudication *3. Nocturnal muscle cramps *4. Coronary artery disease *5. Fibrocystic breast disease *6. Cystic fibrosis *7. In premature infants exposed to high concentration of oxygen *8. As antioxidant ***Interactions for Vitamin E*Oral anticoagulants : Hypoprothrombinemic effect may be increased with possibility of bleeding.
VITAMINAT 120ml syrupCALCIUM PANTOTHENATE -- NICOTINAMIDE -- VITAMIN B1 -- VITAMIN B2 -- VITAMIN B12PHARCOvitamin3.9"Indication Studied for the treatment of many uses such as treatment of testicular torsion, diabetic ulceration, wound healing, acne, obesity, diabetic peripheral polyneuropathy. It has also been investigated for its hypolipidemic effects and as cholesterol lowering agent.*Mechanism of action Pantothenic acid is incorporated into COENZYME A and protects cells against peroxidative damage by increasing the level of GLUTATHIONE."
WINDY 200mg 10 sachetACETYLCYSTEINEPHARCO9"Description *Acetylcysteine (also known as N-acetylcysteine or N-acetyl-L-cysteine or NAC) is primarily used as a mucolytic agent and in the management of acetaminophen poisoning. It is a derivative of cysteine with an acetyl group attached to the amino group of cysteine.**Mechanism of action Acetylcysteine protects against acetaminophen overdose-induced hepatotoxicity by maintaining or restoring hepatic concentrations of glutathione. It does this by producing the glutathione precursor L-cysteine. Glutathione is required to inactivate an intermediate metabolite (N-acetyl-p-benzoquinoneimine or NAPQI) of acetaminophen that is thought to be hepatotoxic. In acetaminophen overdose cases, excessive quantities of this metabolite are formed because the primary metabolic (glucuronide and sulfate conjugation) pathways become saturated. Acetylcysteine may act by reducing the metabolite to the parent compound and/or by providing sulfhydryl for conjugation of the metabolite. Experimental eviden"
YUTOPAR 10mg 20 tab.RITODRINEPHARCO24About Ritodrine*A Beta-2 adrenergic agonist, A tocolytic(uterine relaxant).*Mechanism of Action of Ritodrine*Ritodrine is 2 adrenergic agonist. It binds to ?2 adrenergic receptor on outer membrane of myometrial cell and activates adenylyl cyclase. This will result in an increase in cyclic adenosine monophosphate (cyclic AMP) level and decreases intracellular calcium concentration. The decrease of calcium concentration leads to a relaxation of uterine smooth muscle.*Indications for Ritodrine*1. Management of preterm labour
YUTOPAR 10mg/ml amp.RITODRINEPHARCO12.24About Ritodrine*A Beta-2 adrenergic agonist, A tocolytic(uterine relaxant).*Mechanism of Action of Ritodrine*Ritodrine is 2 adrenergic agonist. It binds to ?2 adrenergic receptor on outer membrane of myometrial cell and activates adenylyl cyclase. This will result in an increase in cyclic adenosine monophosphate (cyclic AMP) level and decreases intracellular calcium concentration. The decrease of calcium concentration leads to a relaxation of uterine smooth muscle.*Indications for Ritodrine*1. Management of preterm labour
ZINC & CASTOR OIL oint. B.P.98CASTOR OIL -- ZINC OXIDEPHARCO3
ZINCORHEA SYRUP 80 MLZINCPHARCO9About Zinc*Trance metal, Dietary mineral, Nutritional supplement,Treatment of zinc deficiency,in wound healing.*Mechanism of Action of Zinc*Zinc acts as a cofactor for more than 70 different enzymes. Zinc dependent enzymes are involved in the metabolism of carbohydrates, lipids, and proteins. Zinc facilitates wound healing, normal growth rates, normal skin hydration and maintains senses of taste and smell. It provides normal growth and tissue repair. It also helps in development of cell mediated immunity.*Indications for Zinc*1. Zinc deficiency *2. Acne vulgaris *3. Chronic skin ulcers *4. Adjunct to antimicrobials *5. Delayed wound healing *6. Alopecia
Trade NameGeneric NameCompanyPharmacology PriceDescription
AMIKABIOTIC 100mg/2ml AMP.AMIKACINPHARCO B5"Description *Amikacin is a semi-synthetic aminoglycoside antibiotic derived from kanamycin A. Similar to other aminoglycosides, amikacin disrupts bacterial protein synthesis by binding to the 30S ribosome of susceptible organisms. Binding interferes with mRNA binding and tRNA acceptor sites leading to the production of non-functional or toxic peptides. Other mechanisms not fully understood may confer the bactericidal effects of amikacin. Amikacin is also nephrotoxic and ototoxic.**Indication :*For short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria, including Pseudomonas species, Escherichia coli, species of indole-positive and indole-negative Proteus, Providencia species, Klebsiella-Enterobacter-Serratia species, and Acinetobacter (Mima-Herellea) species. Amikacin may also be used to treat Mycobacterium avium and Mycobacterium tuberculosis infections."
AMIKABIOTIC 500mg/2ml 3 AMP.AMIKACINPHARCO B33"Description *Amikacin is a semi-synthetic aminoglycoside antibiotic derived from kanamycin A. Similar to other aminoglycosides, amikacin disrupts bacterial protein synthesis by binding to the 30S ribosome of susceptible organisms. Binding interferes with mRNA binding and tRNA acceptor sites leading to the production of non-functional or toxic peptides. Other mechanisms not fully understood may confer the bactericidal effects of amikacin. Amikacin is also nephrotoxic and ototoxic.**Indication :*For short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria, including Pseudomonas species, Escherichia coli, species of indole-positive and indole-negative Proteus, Providencia species, Klebsiella-Enterobacter-Serratia species, and Acinetobacter (Mima-Herellea) species. Amikacin may also be used to treat Mycobacterium avium and Mycobacterium tuberculosis infections."
CEFACLOR 125mg/5ml 60ml susp.U.S.P.23CEFACLORPHARCO BAntibiotic.cephalosporin.Second-generation16.8About Cefaclor*A second-generation cephalosporin antibiotic, Oral Broad-spectrum antibiotics.**Mechanism of Action*Cefaclor is a 2nd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefaclor inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefaclor. *Cefaclor has more activity against ampicillin resistant haemophilus influenzae and branhamella catarrhalis **Indications for Cefaclor*1.Pneumonia & Pulmonary infections *2.Otitismedia *3.Urinary tract infections & genital tract infections *4.Pharyngitis & Tonsillitis *5.Skin & wound infections *6.Bronchitis & Sinusitis
CEFACLOR 250mg 12 Caps.CEFACLORPHARCO BAntibiotic.cephalosporin.Second-generation25.2About Cefaclor*A second-generation cephalosporin antibiotic, Oral Broad-spectrum antibiotics.**Mechanism of Action*Cefaclor is a 2nd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefaclor inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefaclor. *Cefaclor has more activity against ampicillin resistant haemophilus influenzae and branhamella catarrhalis **Indications for Cefaclor*1.Pneumonia & Pulmonary infections *2.Otitismedia *3.Urinary tract infections & genital tract infections *4.Pharyngitis & Tonsillitis *5.Skin & wound infections *6.Bronchitis & Sinusitis
CEFACLOR 250mg/5ml 60ml susp.U.S.P.23CEFACLORPHARCO BAntibiotic.cephalosporin.Second-generation26.4About Cefaclor*A second-generation cephalosporin antibiotic, Oral Broad-spectrum antibiotics.**Mechanism of Action*Cefaclor is a 2nd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefaclor inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefaclor. *Cefaclor has more activity against ampicillin resistant haemophilus influenzae and branhamella catarrhalis **Indications for Cefaclor*1.Pneumonia & Pulmonary infections *2.Otitismedia *3.Urinary tract infections & genital tract infections *4.Pharyngitis & Tonsillitis *5.Skin & wound infections *6.Bronchitis & Sinusitis
CEFACLOR 500mg 12Caps.USP 23CEFACLORPHARCO BAntibiotic.cephalosporin.Second-generation31.5About Cefaclor*A second-generation cephalosporin antibiotic, Oral Broad-spectrum antibiotics.**Mechanism of Action*Cefaclor is a 2nd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefaclor inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefaclor. *Cefaclor has more activity against ampicillin resistant haemophilus influenzae and branhamella catarrhalis **Indications for Cefaclor*1.Pneumonia & Pulmonary infections *2.Otitismedia *3.Urinary tract infections & genital tract infections *4.Pharyngitis & Tonsillitis *5.Skin & wound infections *6.Bronchitis & Sinusitis
CEFAXONE 1gm I.M. vialCEFTRIAXONEPHARCO BAntibiotic.cephalosporin.third-generation36About Ceftriaxone*Third Generation Cephalosporin antibiotic(Parenteral).**Mechanism of Action of Ceftriaxone*Ceftriaxone is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Ceftriaxone inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Ceftriaxone. **Indications for Ceftriaxone*1.Meningitis *2.Septicaemia *3.Typhoid *4.UTI *5.Prophylaxis in surgical infections *6.Lower respiratory tract infections *7.Pneumonia *8.Pelvic inflammatory disease *9.STD *10.Bacteraemia
CEFAXONE 1gm I.V. vialCEFTRIAXONEPHARCO BAntibiotic.cephalosporin.third-generation36About Ceftriaxone*Third Generation Cephalosporin antibiotic(Parenteral).**Mechanism of Action of Ceftriaxone*Ceftriaxone is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Ceftriaxone inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Ceftriaxone. **Indications for Ceftriaxone*1.Meningitis *2.Septicaemia *3.Typhoid *4.UTI *5.Prophylaxis in surgical infections *6.Lower respiratory tract infections *7.Pneumonia *8.Pelvic inflammatory disease *9.STD *10.Bacteraemia
CEFAXONE 250mg I.M.vial.CEFTRIAXONEPHARCO BAntibiotic.cephalosporin.third-generation15About Ceftriaxone*Third Generation Cephalosporin antibiotic(Parenteral).**Mechanism of Action of Ceftriaxone*Ceftriaxone is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Ceftriaxone inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Ceftriaxone. **Indications for Ceftriaxone*1.Meningitis *2.Septicaemia *3.Typhoid *4.UTI *5.Prophylaxis in surgical infections *6.Lower respiratory tract infections *7.Pneumonia *8.Pelvic inflammatory disease *9.STD *10.Bacteraemia
CEFAXONE 250mg I.V.vial.CEFTRIAXONEPHARCO BAntibiotic.cephalosporin.third-generation15About Ceftriaxone*Third Generation Cephalosporin antibiotic(Parenteral).**Mechanism of Action of Ceftriaxone*Ceftriaxone is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Ceftriaxone inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Ceftriaxone. **Indications for Ceftriaxone*1.Meningitis *2.Septicaemia *3.Typhoid *4.UTI *5.Prophylaxis in surgical infections *6.Lower respiratory tract infections *7.Pneumonia *8.Pelvic inflammatory disease *9.STD *10.Bacteraemia
CEFAXONE 2gm I.V. vialCEFTRIAXONEPHARCO BAntibiotic.cephalosporin.third-generation50.5About Ceftriaxone*Third Generation Cephalosporin antibiotic(Parenteral).**Mechanism of Action of Ceftriaxone*Ceftriaxone is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Ceftriaxone inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Ceftriaxone. **Indications for Ceftriaxone*1.Meningitis *2.Septicaemia *3.Typhoid *4.UTI *5.Prophylaxis in surgical infections *6.Lower respiratory tract infections *7.Pneumonia *8.Pelvic inflammatory disease *9.STD *10.Bacteraemia
CEFAXONE 500mg I.M. vialCEFTRIAXONEPHARCO BAntibiotic.cephalosporin.third-generation25.25About Ceftriaxone*Third Generation Cephalosporin antibiotic(Parenteral).**Mechanism of Action of Ceftriaxone*Ceftriaxone is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Ceftriaxone inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Ceftriaxone. **Indications for Ceftriaxone*1.Meningitis *2.Septicaemia *3.Typhoid *4.UTI *5.Prophylaxis in surgical infections *6.Lower respiratory tract infections *7.Pneumonia *8.Pelvic inflammatory disease *9.STD *10.Bacteraemia
CEFAXONE 500mg I.V. vialCEFTRIAXONEPHARCO BAntibiotic.cephalosporin.third-generation25.25About Ceftriaxone*Third Generation Cephalosporin antibiotic(Parenteral).**Mechanism of Action of Ceftriaxone*Ceftriaxone is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Ceftriaxone inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Ceftriaxone. **Indications for Ceftriaxone*1.Meningitis *2.Septicaemia *3.Typhoid *4.UTI *5.Prophylaxis in surgical infections *6.Lower respiratory tract infections *7.Pneumonia *8.Pelvic inflammatory disease *9.STD *10.Bacteraemia
CEFAZONE 0.5gm vialCEFOPERAZONEPHARCO BAntibiotic.cephalosporin.third-generation14.25About Cefoperazone Sodium*A third generation cephalosporin antibiotic, Parenteral antibiotic.**Mechanism of Action of Cefoperazone Sodium*Cefoperazone is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefoperazone inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefoperazone. It has greater action against pseudomonas & has good action against salmonella typhi & B.fragilis**Indications for Cefoperazone Sodium*1.Meningitis *2.Biliary infections *3.Septicemia *4.Infections in immunocompromised patients *5.Urinary tract &genital tract infections *6.Surgical prophylaxis *7.Skin & soft tissue infections *8.Bone & Joint infections *9.Gonorrhea, *10.Peritonitis.
CEFAZONE 1gm vialCEFOPERAZONEPHARCO BAntibiotic.cephalosporin.third-generation24.5About Cefoperazone Sodium*A third generation cephalosporin antibiotic, Parenteral antibiotic.**Mechanism of Action of Cefoperazone Sodium*Cefoperazone is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefoperazone inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefoperazone. It has greater action against pseudomonas & has good action against salmonella typhi & B.fragilis**Indications for Cefoperazone Sodium*1.Meningitis *2.Biliary infections *3.Septicemia *4.Infections in immunocompromised patients *5.Urinary tract &genital tract infections *6.Surgical prophylaxis *7.Skin & soft tissue infections *8.Bone & Joint infections *9.Gonorrhea, *10.Peritonitis.
CEFEPIME 1gm I.M/I.V VialCEFEPIMEPHARCO BAntibiotic.cephalosporin.Fourth-generation38About Cefepime*Fourth Generation cephalosporin antibiotic.**Mechanism of Action of Cefepime*Cefepime is a 3rd generation cephalosporin which exerts its bactericidal action by inhibiting bacterial cell wall synthesis. Cefepime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefipime**Indications for Cefepime*1.Pneumonia *2.Resistant hospital acquired infections *3.Septicemia, *4.Empiric therapy in febrile neutropenic patients *5.Urinary tract infections *6.Pyelonephritis *7.Tonsillitis, Pharyngitis etc. *8.Skin & soft tissue infections
CEFEPIME 2gm vial.CEFEPIMEPHARCO BAntibiotic.cephalosporin.Fourth-generation54About Cefepime*Fourth Generation cephalosporin antibiotic.**Mechanism of Action of Cefepime*Cefepime is a 3rd generation cephalosporin which exerts its bactericidal action by inhibiting bacterial cell wall synthesis. Cefepime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefipime**Indications for Cefepime*1.Pneumonia *2.Resistant hospital acquired infections *3.Septicemia, *4.Empiric therapy in febrile neutropenic patients *5.Urinary tract infections *6.Pyelonephritis *7.Tonsillitis, Pharyngitis etc. *8.Skin & soft tissue infections
CEFEPIME 500mg I.M/I.V vialCEFEPIMEPHARCO BAntibiotic.cephalosporin.Fourth-generation25.25About Cefepime*Fourth Generation cephalosporin antibiotic.**Mechanism of Action of Cefepime*Cefepime is a 3rd generation cephalosporin which exerts its bactericidal action by inhibiting bacterial cell wall synthesis. Cefepime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefipime**Indications for Cefepime*1.Pneumonia *2.Resistant hospital acquired infections *3.Septicemia, *4.Empiric therapy in febrile neutropenic patients *5.Urinary tract infections *6.Pyelonephritis *7.Tonsillitis, Pharyngitis etc. *8.Skin & soft tissue infections
CEFIXIME 100mg/5ml 30ml susp.CEFIXIMEPHARCO BAntibiotic.cephalosporin.third-generation21.6About Cefixime*Third Generation Cephalosporin Oral antibiotic**Mechanism of Action of Cefixime*Cefixime is an orally active 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefixime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefixime. It is highly active against enterobacteriaceae, Haemophilus influenzae, Streptococcus pyogens & Streptococcus pneumonia &many beta lactamase producing bacteria.**Indications for Cefixime*1.Tonsillitis *2.Pharyngitis *3.Otitismedia *4.Bronchitis *5.Urinary tract infections *6.Gonorrhea *7.Infections caused by susceptible organisms.
CEFIXIME 100mg/5ml 60ml susp.CEFIXIMEPHARCO BAntibiotic.cephalosporin.third-generation32.4About Cefixime*Third Generation Cephalosporin Oral antibiotic**Mechanism of Action of Cefixime*Cefixime is an orally active 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefixime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefixime. It is highly active against enterobacteriaceae, Haemophilus influenzae, Streptococcus pyogens & Streptococcus pneumonia &many beta lactamase producing bacteria.**Indications for Cefixime*1.Tonsillitis *2.Pharyngitis *3.Otitismedia *4.Bronchitis *5.Urinary tract infections *6.Gonorrhea *7.Infections caused by susceptible organisms.
CEFORAN 1gm vialCEFOTAXIMEPHARCO BAntibiotic.cephalosporin.third-generation21.75About Cefotaxime*Third Generation cephalosporin Parenteral antibiotic.**Mechanism of Action of Cefotaxime*Cefotaxime is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & aerobic gram negative organisms by inhibiting bacterial cell wall synthesis. Cefotaxime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefotaxime**Indications for Cefotaxime*1.Meningitis *2.Resistant hospital acquired infections *3.Septicemia *4.Infections in immunocompromised patients *5.Urinary tract &genital tract infections *6.Surgical prophylaxis *7.Skin & soft tissue infections *8.Bone & Joint infections *9.Gonorrhea. **Interactions for Cefotaxime*Synergy with aminoglycosides.
CEFORAN 2gm vialCEFOTAXIMEPHARCO BAntibiotic.cephalosporin.third-generation32.5About Cefotaxime*Third Generation cephalosporin Parenteral antibiotic.**Mechanism of Action of Cefotaxime*Cefotaxime is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & aerobic gram negative organisms by inhibiting bacterial cell wall synthesis. Cefotaxime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefotaxime**Indications for Cefotaxime*1.Meningitis *2.Resistant hospital acquired infections *3.Septicemia *4.Infections in immunocompromised patients *5.Urinary tract &genital tract infections *6.Surgical prophylaxis *7.Skin & soft tissue infections *8.Bone & Joint infections *9.Gonorrhea. **Interactions for Cefotaxime*Synergy with aminoglycosides.
CEFORAN 500mg vialCEFOTAXIMEPHARCO BAntibiotic.cephalosporin.third-generation15About Cefotaxime*Third Generation cephalosporin Parenteral antibiotic.**Mechanism of Action of Cefotaxime*Cefotaxime is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & aerobic gram negative organisms by inhibiting bacterial cell wall synthesis. Cefotaxime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefotaxime**Indications for Cefotaxime*1.Meningitis *2.Resistant hospital acquired infections *3.Septicemia *4.Infections in immunocompromised patients *5.Urinary tract &genital tract infections *6.Surgical prophylaxis *7.Skin & soft tissue infections *8.Bone & Joint infections *9.Gonorrhea. **Interactions for Cefotaxime*Synergy with aminoglycosides.
CEFUMAX 1500mg I.M./I.V.vialCEFUROXIMEPHARCO BAntibiotic.cephalosporin.Second-generation31.2About Cefuroxime*Second Generation Cephalosporin antibiotic.**Mechanism of Action of Cefuroxime*Cefuroxime is a 2nd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefuroxime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefuroxime **Indications for Cefuroxime*1.Meningitis caused by H.influenzae, meningococci, pneumococci etc. *2.Gonorrhea *3.Pneumonia & Pulmonary infections *4.Infections caused by ampicillin resistant H. influenzae *5.Septicemia *6.Tonsillitis *7.Pharyngitis *8.Urinary tract infections *9.Otitis media
CEFUMAX 250mg I.V./I.M.vialCEFUROXIMEPHARCO BAntibiotic.cephalosporin.Second-generation8About Cefuroxime*Second Generation Cephalosporin antibiotic.**Mechanism of Action of Cefuroxime*Cefuroxime is a 2nd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefuroxime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefuroxime **Indications for Cefuroxime*1.Meningitis caused by H.influenzae, meningococci, pneumococci etc. *2.Gonorrhea *3.Pneumonia & Pulmonary infections *4.Infections caused by ampicillin resistant H. influenzae *5.Septicemia *6.Tonsillitis *7.Pharyngitis *8.Urinary tract infections *9.Otitis media
CEFUMAX 750mg I.M./I.V.vialCEFUROXIMEPHARCO BAntibiotic.cephalosporin.Second-generation19.2About Cefuroxime*Second Generation Cephalosporin antibiotic.**Mechanism of Action of Cefuroxime*Cefuroxime is a 2nd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefuroxime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefuroxime **Indications for Cefuroxime*1.Meningitis caused by H.influenzae, meningococci, pneumococci etc. *2.Gonorrhea *3.Pneumonia & Pulmonary infections *4.Infections caused by ampicillin resistant H. influenzae *5.Septicemia *6.Tonsillitis *7.Pharyngitis *8.Urinary tract infections *9.Otitis media
CEFZIM 1gm vialCEFTAZIDIMEPHARCO BAntibiotic.cephalosporin.third-generation30.75About Ceftazidime*Third Generation Cephalosporin antibiotic, Parenteral antibiotic.**Mechanism of Action of Ceftazidime*Ceftazidime is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Ceftazidime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Ceftazidime.It is more active against pseudomonas.**Indications for Ceftazidime*1.Febrile neutropenic patients with haematological malignancies *2.Burn infections *3.Respiratory tract infections *4.Urinogenital tract infections *5.Bone & Joint infections *6.Septicemia *7.CNS infections *8.Skin & wound infections *9.Meningitis.
CEFZIM 250mg vialCEFTAZIDIMEPHARCO BAntibiotic.cephalosporin.third-generation13.5About Ceftazidime*Third Generation Cephalosporin antibiotic, Parenteral antibiotic.**Mechanism of Action of Ceftazidime*Ceftazidime is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Ceftazidime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Ceftazidime.It is more active against pseudomonas.**Indications for Ceftazidime*1.Febrile neutropenic patients with haematological malignancies *2.Burn infections *3.Respiratory tract infections *4.Urinogenital tract infections *5.Bone & Joint infections *6.Septicemia *7.CNS infections *8.Skin & wound infections *9.Meningitis.
CEFZIM 2gm vialCEFTAZIDIMEPHARCO BAntibiotic.cephalosporin.third-generation39.75About Ceftazidime*Third Generation Cephalosporin antibiotic, Parenteral antibiotic.**Mechanism of Action of Ceftazidime*Ceftazidime is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Ceftazidime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Ceftazidime.It is more active against pseudomonas.**Indications for Ceftazidime*1.Febrile neutropenic patients with haematological malignancies *2.Burn infections *3.Respiratory tract infections *4.Urinogenital tract infections *5.Bone & Joint infections *6.Septicemia *7.CNS infections *8.Skin & wound infections *9.Meningitis.
CEFZIM 500mg vialCEFTAZIDIMEPHARCO BAntibiotic.cephalosporin.third-generation19About Ceftazidime*Third Generation Cephalosporin antibiotic, Parenteral antibiotic.**Mechanism of Action of Ceftazidime*Ceftazidime is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Ceftazidime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Ceftazidime.It is more active against pseudomonas.**Indications for Ceftazidime*1.Febrile neutropenic patients with haematological malignancies *2.Burn infections *3.Respiratory tract infections *4.Urinogenital tract infections *5.Bone & Joint infections *6.Septicemia *7.CNS infections *8.Skin & wound infections *9.Meningitis.
CEPHARIN 1gm vialCEFAPIRINPHARCO BAntibiotic.cephalosporin.First-generation9.5"Description *Cefapirin (INN, also spelled cephapirin) is an injectable, first-generation cephalosporin antibiotic.*Mechanism of action The bactericidal activity of cephapirin results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs)."
CEPHARIN 500mg vialCEFAPIRINPHARCO BAntibiotic.cephalosporin.First-generation7"Description *Cefapirin (INN, also spelled cephapirin) is an injectable, first-generation cephalosporin antibiotic.*Mechanism of action The bactericidal activity of cephapirin results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs)."
CEPHOXIN 125MG/5ML DRY SUSP. 60 MLCEFALEXINPHARCO BAntibiotic.cephalosporin.First-generation6About Cefalexin*A first-generation cephalosporin antibiotic.**Mechanism of Action *Cephalexin is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cephalexin inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cephalexin **Indications for Cefalexin*1.Respiratory tract infections *2.Urinary tract infections *3.Surgical prophylaxis *4.Skin infections` *5.Joint & bone infections *6.Otitis media` *7.Reproductive tract infections` **Contra-indications*1.Hypersensitivity to cephalosporins *2.Porphyria *3.Neuromuscular disorders.
CEPHOXIN 1g vialCEFALEXINPHARCO BAntibiotic.cephalosporin.First-generation9About Cefalexin*A first-generation cephalosporin antibiotic.**Mechanism of Action *Cephalexin is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cephalexin inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cephalexin **Indications for Cefalexin*1.Respiratory tract infections *2.Urinary tract infections *3.Surgical prophylaxis *4.Skin infections` *5.Joint & bone infections *6.Otitis media` *7.Reproductive tract infections` **Contra-indications*1.Hypersensitivity to cephalosporins *2.Porphyria *3.Neuromuscular disorders.
CEPHOXIN 1gm 8 tab.CEFALEXINPHARCO BAntibiotic.cephalosporin.First-generation13.8About Cefalexin*A first-generation cephalosporin antibiotic.**Mechanism of Action *Cephalexin is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cephalexin inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cephalexin **Indications for Cefalexin*1.Respiratory tract infections *2.Urinary tract infections *3.Surgical prophylaxis *4.Skin infections` *5.Joint & bone infections *6.Otitis media` *7.Reproductive tract infections` **Contra-indications*1.Hypersensitivity to cephalosporins *2.Porphyria *3.Neuromuscular disorders.
CEPHOXIN 250MG/5ML DRY SUSP. 60 MLCEFALEXINPHARCO BAntibiotic.cephalosporin.First-generation6.5About Cefalexin*A first-generation cephalosporin antibiotic.**Mechanism of Action *Cephalexin is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cephalexin inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cephalexin **Indications for Cefalexin*1.Respiratory tract infections *2.Urinary tract infections *3.Surgical prophylaxis *4.Skin infections` *5.Joint & bone infections *6.Otitis media` *7.Reproductive tract infections` **Contra-indications*1.Hypersensitivity to cephalosporins *2.Porphyria *3.Neuromuscular disorders.
CEPHOXIN 500mg 12 tab.CEFALEXINPHARCO BAntibiotic.cephalosporin.First-generation10.5About Cefalexin*A first-generation cephalosporin antibiotic.**Mechanism of Action *Cephalexin is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cephalexin inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cephalexin **Indications for Cefalexin*1.Respiratory tract infections *2.Urinary tract infections *3.Surgical prophylaxis *4.Skin infections` *5.Joint & bone infections *6.Otitis media` *7.Reproductive tract infections` **Contra-indications*1.Hypersensitivity to cephalosporins *2.Porphyria *3.Neuromuscular disorders.
CEPHOXIN 500mg vialCEFALEXINPHARCO BAntibiotic.cephalosporin.First-generation6About Cefalexin*A first-generation cephalosporin antibiotic.**Mechanism of Action *Cephalexin is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cephalexin inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cephalexin **Indications for Cefalexin*1.Respiratory tract infections *2.Urinary tract infections *3.Surgical prophylaxis *4.Skin infections` *5.Joint & bone infections *6.Otitis media` *7.Reproductive tract infections` **Contra-indications*1.Hypersensitivity to cephalosporins *2.Porphyria *3.Neuromuscular disorders.
CURISAFE 125mg/5ml 60ml susp.CEFADROXILPHARCO BAntibiotic.cephalosporin.First-generation12About Cefadroxil*First Generation Cephalosporin, para-hydroxy derivative of cefalexin, Oral broad-spectrum antibiotic**Mechanism of Action *Cefadroxil is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefadroxil inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefadroxil **Indications for Cefadroxil*1. Urinay tract infections *2. Tonsillitis & Pharyngitis *3. Skin &soft tissue infections *4. Otitis media. **Contra-indications of Cefadroxil*1.Hypersensitivity to cephalosporins *2.Porphyria *3.Neuromuscular disorders. *
CURISAFE 1GM 8 TABS.CEFADROXILPHARCO BAntibiotic.cephalosporin.First-generation18About Cefadroxil*First Generation Cephalosporin, para-hydroxy derivative of cefalexin, Oral broad-spectrum antibiotic**Mechanism of Action *Cefadroxil is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefadroxil inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefadroxil **Indications for Cefadroxil*1. Urinay tract infections *2. Tonsillitis & Pharyngitis *3. Skin &soft tissue infections *4. Otitis media. **Contra-indications of Cefadroxil*1.Hypersensitivity to cephalosporins *2.Porphyria *3.Neuromuscular disorders. *
CURISAFE 250mg/5ml 60ml susp.CEFADROXILPHARCO BAntibiotic.cephalosporin.First-generation15About Cefadroxil*First Generation Cephalosporin, para-hydroxy derivative of cefalexin, Oral broad-spectrum antibiotic**Mechanism of Action *Cefadroxil is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefadroxil inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefadroxil **Indications for Cefadroxil*1. Urinay tract infections *2. Tonsillitis & Pharyngitis *3. Skin &soft tissue infections *4. Otitis media. **Contra-indications of Cefadroxil*1.Hypersensitivity to cephalosporins *2.Porphyria *3.Neuromuscular disorders. *
CURISAFE 500mg 8 Caps.CEFADROXILPHARCO BAntibiotic.cephalosporin.First-generation15About Cefadroxil*First Generation Cephalosporin, para-hydroxy derivative of cefalexin, Oral broad-spectrum antibiotic**Mechanism of Action *Cefadroxil is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefadroxil inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefadroxil **Indications for Cefadroxil*1. Urinay tract infections *2. Tonsillitis & Pharyngitis *3. Skin &soft tissue infections *4. Otitis media. **Contra-indications of Cefadroxil*1.Hypersensitivity to cephalosporins *2.Porphyria *3.Neuromuscular disorders. *
CURISAFE 500mg/5ml 60ml susp.CEFADROXILPHARCO BAntibiotic.cephalosporin.First-generation20About Cefadroxil*First Generation Cephalosporin, para-hydroxy derivative of cefalexin, Oral broad-spectrum antibiotic**Mechanism of Action *Cefadroxil is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefadroxil inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefadroxil **Indications for Cefadroxil*1. Urinay tract infections *2. Tonsillitis & Pharyngitis *3. Skin &soft tissue infections *4. Otitis media. **Contra-indications of Cefadroxil*1.Hypersensitivity to cephalosporins *2.Porphyria *3.Neuromuscular disorders. *
CURISAFE pediatric drops 100mg/ml oral dropsCEFADROXILPHARCO BAntibiotic.cephalosporin.First-generation7.15About Cefadroxil*First Generation Cephalosporin, para-hydroxy derivative of cefalexin, Oral broad-spectrum antibiotic**Mechanism of Action *Cefadroxil is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefadroxil inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefadroxil **Indications for Cefadroxil*1. Urinay tract infections *2. Tonsillitis & Pharyngitis *3. Skin &soft tissue infections *4. Otitis media. **Contra-indications of Cefadroxil*1.Hypersensitivity to cephalosporins *2.Porphyria *3.Neuromuscular disorders. *
FARCOSEF 1gm I.V./I.M.vialCEPHRADINEPHARCO B9.75"Description *A semi-synthetic cephalosporin antibiotic.**Mechanism of action Cefradine* is a first generation cephalosporin antibiotic with a spectrum of activity similar to Cefalexin. Cefradine, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins- it is possible that Cefradine interferes with an autolysin inhibitor."
FARCOSEF 250mg vialCEPHRADINEPHARCO B6"Description *A semi-synthetic cephalosporin antibiotic.**Mechanism of action Cefradine* is a first generation cephalosporin antibiotic with a spectrum of activity similar to Cefalexin. Cefradine, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins- it is possible that Cefradine interferes with an autolysin inhibitor."
FARCOSEF 500mg vialCEPHRADINEPHARCO B7"Description *A semi-synthetic cephalosporin antibiotic.**Mechanism of action Cefradine* is a first generation cephalosporin antibiotic with a spectrum of activity similar to Cefalexin. Cefradine, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins- it is possible that Cefradine interferes with an autolysin inhibitor."
GRANIBIOTIC cream 15 GMGRAMICIDIN -- NEOMYCIN -- NYSTATIN -- TRIAMCINOLONEPHARCO B7About Gramicidin*Gramicidin is active against most of the gram positive bacteria and some gram negative bacteria. Its use is limited to topical use only, since systemic use may produce haemolysis.Gramicidin produces its action by increasing the permeability of cell wall. While the permeability increases inorganic monovalent cations enter to the bacterial cell wall and destroy the ion gradient between the cytoplasm and the extra cellular environment.*Special Precautions while taking Gramicidin*1.Use caution while driving vehicle, operating machine and other activities which requires clear vision. *2.Patients using contact lens *Indications for Gramicidin*Bacterial infections of eye
HYDROXOCOBALAMIN 1000 MCG 3 AMP.HYDROXOCOBALAMINPHARCO B8"Preservative free*Description *Injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency.**Mechanism of action *Vitamin B12 exists in four major forms referred to collectively as cobalamins- deoxyadenosylcobalamin, methylcobalamin, hydroxocobalamin, and cyanocobalamin. Two of these, methylcobalamin and 5-deoxyadenosyl cobalamin, are primarily used by the body. Methionine synthase needs methylcobalamin as a cofactor. This enzyme is involved in the conversion of the amino acid homocysteine into methionine. Methionine in turn is required for DNA methylation. 5-Deoxyadenosyl cobalamin is a cofactor needed by the enzyme that converts L-methylmalonyl-CoA to succinyl-CoA. This conversion is an important step in the extraction of energy from proteins and fats. Furthermore, succinyl CoA is necessary for the production of hemoglobin, the substances that carries oxygen in red blood cells."
HYDROXOCOBALAMIN 1500 MCG 3 AMP.HYDROXOCOBALAMINPHARCO B13.5"Description *Injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency.**Mechanism of action *Vitamin B12 exists in four major forms referred to collectively as cobalamins- deoxyadenosylcobalamin, methylcobalamin, hydroxocobalamin, and cyanocobalamin. Two of these, methylcobalamin and 5-deoxyadenosyl cobalamin, are primarily used by the body. Methionine synthase needs methylcobalamin as a cofactor. This enzyme is involved in the conversion of the amino acid homocysteine into methionine. Methionine in turn is required for DNA methylation. 5-Deoxyadenosyl cobalamin is a cofactor needed by the enzyme that converts L-methylmalonyl-CoA to succinyl-CoA. This conversion is an important step in the extraction of energy from proteins and fats. Furthermore, succinyl CoA is necessary for the production of hemoglobin, the substances that carries oxygen in red blood cells."
LIDOCAINE HYDROCHLORIDE 1% & EPINEPHRINE 0.01MG/ML 5 AMP. 10 MLLIDOCAINEPHARCO BAnalgesic.Local Anesthetic43.5
LIDOCAINE HYDROCHLORIDE 10MG/ML AMP 3.5MLLIDOCAINEPHARCO BAnalgesic.Local Anesthetic2.62"Indication *For production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks.**Mechanism of action *Lidocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses thereby effecting local anesthetic action. Lidocaine alters signal conduction in neurons by blocking the fast voltage gated sodium (Na -- ) channels in the neuronal cell membrane that are responsible for signal propagation. With sufficient blockage the membrane of the postsynaptic neuron will not depolarize and will thus fail to transmit an action potential. This creates the anaesthetic effect by not merely preventing pain signals from propagating to the brain but by aborting their birth in the first place."
LIDOCAINE HYDROCHLORIDE 10MG/ML AMP. 2 MLLIDOCAINEPHARCO BAnalgesic.Local Anesthetic2"Indication *For production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks.**Mechanism of action *Lidocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses thereby effecting local anesthetic action. Lidocaine alters signal conduction in neurons by blocking the fast voltage gated sodium (Na -- ) channels in the neuronal cell membrane that are responsible for signal propagation. With sufficient blockage the membrane of the postsynaptic neuron will not depolarize and will thus fail to transmit an action potential. This creates the anaesthetic effect by not merely preventing pain signals from propagating to the brain but by aborting their birth in the first place."
LIDOCAINE HYDROCHLORIDE 10MG/ML AMP. 5 MLLIDOCAINEPHARCO BAnalgesic.Local Anesthetic3"Indication *For production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks.**Mechanism of action *Lidocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses thereby effecting local anesthetic action. Lidocaine alters signal conduction in neurons by blocking the fast voltage gated sodium (Na -- ) channels in the neuronal cell membrane that are responsible for signal propagation. With sufficient blockage the membrane of the postsynaptic neuron will not depolarize and will thus fail to transmit an action potential. This creates the anaesthetic effect by not merely preventing pain signals from propagating to the brain but by aborting their birth in the first place."
LIDOCAINE HYDROCHLORIDE 2% & EPINEPHRINE 0.01MG/ML 5 AMP. 10 MLLIDOCAINEPHARCO BAnalgesic.Local Anesthetic43.5
PARACETAMOL-PHARCO B 1% soln. for I.V. inf.PARACETAMOL(ACETAMINOPHEN)PHARCO BAntipyretic12.5About Paracetamol*Acetanilide derivative, Non narcotic Analgesic,Antipyretic.*Mechanism of Action of Paracetamol*Paracetamol has analgesic and antipyretic action. *It is more active on cyclo-oxygenase enzyme in brain. Peripherally it is a poor inhibitor of prostaglandin synthesis. *Analgesic action: Paracetamol raises the pain threshold and produces analgesic effect. *Antipyretic action: Paracetamol lowers fever by direct action on the thermoregulatory centre in the Hypothalamus and block the effects of endogenous pyrogen. *Indications for Paracetamol*1. To relieve pain and fever *2. Acute gout *3. Migraine *Interactions for Paracetamol*Cholestyramine: Reduces absorption of paracetamol. *Charcoal: Activated, administered immediately reduces absorption of paracetamol. *Domperidone and metochlopramide: Enhance absorption of paracetamol. *Alcohol: Chronic excessive ingestion of alcohol potentiates hepatotoxicity of paracetamol. *
PARACETAMOL-PHARCO B 1% soln. I.V. inf.PARACETAMOL(ACETAMINOPHEN)PHARCO BAntipyretic25.25About Paracetamol*Acetanilide derivative, Non narcotic Analgesic,Antipyretic.*Mechanism of Action of Paracetamol*Paracetamol has analgesic and antipyretic action. *It is more active on cyclo-oxygenase enzyme in brain. Peripherally it is a poor inhibitor of prostaglandin synthesis. *Analgesic action: Paracetamol raises the pain threshold and produces analgesic effect. *Antipyretic action: Paracetamol lowers fever by direct action on the thermoregulatory centre in the Hypothalamus and block the effects of endogenous pyrogen. *Indications for Paracetamol*1. To relieve pain and fever *2. Acute gout *3. Migraine *Interactions for Paracetamol*Cholestyramine: Reduces absorption of paracetamol. *Charcoal: Activated, administered immediately reduces absorption of paracetamol. *Domperidone and metochlopramide: Enhance absorption of paracetamol. *Alcohol: Chronic excessive ingestion of alcohol potentiates hepatotoxicity of paracetamol. *
PODACEF 100mg 10 F.C.tab.CEFPODOXIMEPHARCO BAntibiotic.cephalosporin.third-generation26.4About Cefpodoxime*Third Generation Cephalosporin antibiotic, Oral antibiotic.**Mechanism of Action of Cefpodoxime*Cefpodoxime is a 3rd generation cephalosporin which exerts its bactericidal action mainly against gram positive organisms by inhibiting bacterial cell wall synthesis. Cefpodoxime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefpodoxime. *It is active against enterobacteriaceae, streptococci ,staphylococci aureus, & H. influenzae. **Indications for Cefpodoxime*1.Pneumonia, bronchitis &other respiratory tract infections *2.Sinusitis *3.Urinary tract &genital tract infections *4.Gonorrhea & rectal gonococcal infections *5.Skin infections *6.Otitismedia *7.Tonsillitis, Pharyngitis
PODACEF 100mg/5ml 60ml susp..CEFPODOXIMEPHARCO BAntibiotic.cephalosporin.third-generation24About Cefpodoxime*Third Generation Cephalosporin antibiotic, Oral antibiotic.**Mechanism of Action of Cefpodoxime*Cefpodoxime is a 3rd generation cephalosporin which exerts its bactericidal action mainly against gram positive organisms by inhibiting bacterial cell wall synthesis. Cefpodoxime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefpodoxime. *It is active against enterobacteriaceae, streptococci ,staphylococci aureus, & H. influenzae. **Indications for Cefpodoxime*1.Pneumonia, bronchitis &other respiratory tract infections *2.Sinusitis *3.Urinary tract &genital tract infections *4.Gonorrhea & rectal gonococcal infections *5.Skin infections *6.Otitismedia *7.Tonsillitis, Pharyngitis
PODACEF 200mg 10 f.c.tab.CEFPODOXIMEPHARCO BAntibiotic.cephalosporin.third-generation31.5About Cefpodoxime*Third Generation Cephalosporin antibiotic, Oral antibiotic.**Mechanism of Action of Cefpodoxime*Cefpodoxime is a 3rd generation cephalosporin which exerts its bactericidal action mainly against gram positive organisms by inhibiting bacterial cell wall synthesis. Cefpodoxime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefpodoxime. *It is active against enterobacteriaceae, streptococci ,staphylococci aureus, & H. influenzae. **Indications for Cefpodoxime*1.Pneumonia, bronchitis &other respiratory tract infections *2.Sinusitis *3.Urinary tract &genital tract infections *4.Gonorrhea & rectal gonococcal infections *5.Skin infections *6.Otitismedia *7.Tonsillitis, Pharyngitis
PODACEF 40mg/5ml 60ml susp..CEFPODOXIMEPHARCO BAntibiotic.cephalosporin.third-generation25.2About Cefpodoxime*Third Generation Cephalosporin antibiotic, Oral antibiotic.**Mechanism of Action of Cefpodoxime*Cefpodoxime is a 3rd generation cephalosporin which exerts its bactericidal action mainly against gram positive organisms by inhibiting bacterial cell wall synthesis. Cefpodoxime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefpodoxime. *It is active against enterobacteriaceae, streptococci ,staphylococci aureus, & H. influenzae. **Indications for Cefpodoxime*1.Pneumonia, bronchitis &other respiratory tract infections *2.Sinusitis *3.Urinary tract &genital tract infections *4.Gonorrhea & rectal gonococcal infections *5.Skin infections *6.Otitismedia *7.Tonsillitis, Pharyngitis
VASLOW 10mg/160mg/12.5MG 10 F.C. tab.AMLODIPINE -- HYDROCHLOROTHIAZIDE -- VALSARTANPHARCO BAnti-hypertensive. combined angiotensin blocker with calcium channel blocker34Valsartan is a nonpeptide, orally active, and specific angiotensin II antagonist acting on the AT1 receptor subtype. ** (amlodipine and valsartan) is indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes, including amlodipine and the ARB class to which valsartan principally belongs. There are no controlled trials demonstrating risk reduction with this medicine.
VASLOW 5mg/160mg/12.5MG 10 F.C. tab.AMLODIPINE -- HYDROCHLOROTHIAZIDE -- VALSARTANPHARCO BAnti-hypertensive. combined angiotensin blocker with calcium channel blocker31.5Valsartan is a nonpeptide, orally active, and specific angiotensin II antagonist acting on the AT1 receptor subtype. ** (amlodipine and valsartan) is indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes, including amlodipine and the ARB class to which valsartan principally belongs. There are no controlled trials demonstrating risk reduction with this medicine.
ZILOSPORE 125mg PD. FOR ORAL SUSP. 60 MLCEFPROZILPHARCO BAntibiotic.cephalosporin.Second-generation20.4About Cefprozil*Second Generation Cephalosporin antibiotic, Oral antibiotic.**Mechanism of Action of Cefprozil*Cefprozil is a short acting 2nd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefprozil inhibits transpeptidase & thus prevents cross linking of bacterial cell wall.**Indications for Cefprozil*1.Pharyngitis *2.Sinusitis *3.Pneumonia *4.Acute Bronchitis *5.Skin infection *6.Tonsillitis *7.Otitis media
ZILOSPORE 250mg PD. FOR ORAL SUSP. 60 MLCEFPROZILPHARCO BAntibiotic.cephalosporin.Second-generation25.2About Cefprozil*Second Generation Cephalosporin antibiotic, Oral antibiotic.**Mechanism of Action of Cefprozil*Cefprozil is a short acting 2nd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefprozil inhibits transpeptidase & thus prevents cross linking of bacterial cell wall.**Indications for Cefprozil*1.Pharyngitis *2.Sinusitis *3.Pneumonia *4.Acute Bronchitis *5.Skin infection *6.Tonsillitis *7.Otitis media
ZILOSPORE 500mg 10 F.C.tab.CEFPROZILPHARCO BAntibiotic.cephalosporin.Second-generation35About Cefprozil*Second Generation Cephalosporin antibiotic, Oral antibiotic.**Mechanism of Action of Cefprozil*Cefprozil is a short acting 2nd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefprozil inhibits transpeptidase & thus prevents cross linking of bacterial cell wall.**Indications for Cefprozil*1.Pharyngitis *2.Sinusitis *3.Pneumonia *4.Acute Bronchitis *5.Skin infection *6.Tonsillitis *7.Otitis media
ZINOL 1gm I.M./I.V.vial.CEFAZOLINPHARCO BAntibiotic.cephalosporin.First-generation16.2"Description *A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis.**Indication *Mainly used to treat bacterial infections of the skin. It can also be used to treat moderately severe bacterial infections involving the lung, bone, joint, stomach, blood, heart valve, and urinary tract. It is clinically effective against infections caused by staphylococci and streptococci species of Gram positive bacteria. May be used for surgical prophylaxis- if required metronidazole may be added to cover B. fragilis.**Mechanism of action In vitro tests demonstrate that the bactericidal action of cephalosporins results from inhibition of cell wall synthesis. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins."
ZINOL 250mg vialCEFAZOLINPHARCO BAntibiotic.cephalosporin.First-generation6.5"Description *A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis.**Indication *Mainly used to treat bacterial infections of the skin. It can also be used to treat moderately severe bacterial infections involving the lung, bone, joint, stomach, blood, heart valve, and urinary tract. It is clinically effective against infections caused by staphylococci and streptococci species of Gram positive bacteria. May be used for surgical prophylaxis- if required metronidazole may be added to cover B. fragilis.**Mechanism of action In vitro tests demonstrate that the bactericidal action of cephalosporins results from inhibition of cell wall synthesis. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins."
ZINOL 500mg vialCEFAZOLINPHARCO BAntibiotic.cephalosporin.First-generation8.5"Description *A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis.**Indication *Mainly used to treat bacterial infections of the skin. It can also be used to treat moderately severe bacterial infections involving the lung, bone, joint, stomach, blood, heart valve, and urinary tract. It is clinically effective against infections caused by staphylococci and streptococci species of Gram positive bacteria. May be used for surgical prophylaxis- if required metronidazole may be added to cover B. fragilis.**Mechanism of action In vitro tests demonstrate that the bactericidal action of cephalosporins results from inhibition of cell wall synthesis. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins."
ZONACTAM 1.5g I.M. / I.V. VIALCEFOPERAZONE -- SULBACTAMPHARCO B25Indications for Cefoperazone Sodium -- Sulbactam Sodium*It is a combination of third generation Cephalosporins Cefperazone sodium and Beta-lactamase inhibitor Sulbactam. *1.Pharyngitis *2.Tonsillitis *3.Pneumonia *4.Bronchitis *5.Other respiratory tract infections *6.Septicemia *7.Meningitis *8.Urinogenital tract infections *9.Bone & Joint infections *10.Gonorrhea *11.Endometritis *12.Skin & Soft tissue infections *13.Pelvic inflammatory diseases *14.Intra abdominal infections *About Cefoperazone Sodium*A third generation cephalosporin antibiotic, Parenteral antibiotic.*About Sulbactam Sodium*An irreversible ?-lactamase inhibitor, To increase the antibacterial activity of penicillins and cephalosporins against ?-lactamase?producing organisms.

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