GSK

Company Information

We are a science-led global healthcare company with a special purpose: to help people do more, feel better, live longer.


We have 3 global businesses that research, develop and manufacture innovative pharmaceutical medicines, vaccines and consumer healthcare products.

Our goal is to be one of the world’s most innovative, best performing and trusted healthcare companies.

Our values and expectations are at the heart of everything we do and help define our culture - so that together we can deliver extraordinary things for our patients and consumers and make GSK a brilliant place to work.

Our values are Patient focus, Transparency, Respect, Integrity.
Our expectations are Courage, Accountability, Development, Teamwork.

Our Pharmaceuticals business has a broad portfolio of innovative and established medicines with commercial leadership in respiratory and HIV. Our R&D approach focuses on science related to the immune system, use of genetics and advanced technologies.


Our Vaccines business has a broad portfolio and innovative pipeline of vaccines to help protect people throughout life. We deliver over two million vaccine doses per day to people living in over 160 countries.


Our Consumer Healthcare business develops and markets an innovative portfolio of consumer preferred and expert recommended brands in the Pain relief, Respiratory, Digestive health, Oral health, Nutrition and Skin health categories.

On 19 December 2018 we announced our agreement with Pfizer to form a new world-leading Consumer Healthcare Joint Venture. Within 3 years of the closing of the transaction, we intend to separate the Joint Venture via a demerger. With our future intention to separate, the transaction also presents a clear pathway forward for us to create a new global Pharmaceuticals/Vaccines company, and a new world-leading Consumer Healthcare company.



  • No. of Employees: Big Organization      10.000+

  • Range of expected salary for Med. Rep.: After Interview

  • Car Policy: Yes

  • Incentive scheme: yes

  • Factory: yes

  • Company rank (IMS) 2018: 2

  • company link: https://www.gsk.com

Products

Trade NameGeneric NameCompanyPharmacology PriceDescription
ABILAXINE 10mg 5 adult supp.BISACODYLGLAXO SMITHKLINE4About Bisacodyl*Diphenyl methane derivative ,Stimulant (irritant)Laxative**Mechanism of Action of Bisacodyl*Bisacodyl is a stimulant (irritant) laxative. It acts directly on the colonic mucosa-where it stimulates sensory nerve endings in the walls of the intestine and the rectum to produce parasympathetic reflexes resulting in increased peristaltic contractions of the colon and cause defecation.**Indications for Bisacodyl*1.Bowel evacuation in prior to radiological examinations *2.Constipation *3.Laxative in postoperative, ante partum, or postpartum care**Contra-indications of Bisacodyl*1.Hypersensitivity to Bisacodyl *2.Intestinal obstruction *3.Obstruction of the intestines due to loss of intestinal movement *4.Severe dehydration *5.Sudden abdominal conditions requiring surgery (appendicitis) *6.Sudden attacks of inflammatory bowel disease (ulcerative colitis or Crohn`s disease) *7.Anal fissure *8.Ulcerative proctitis
ABILAXINE 5 mg 20 coated tab.BISACODYLGLAXO SMITHKLINE4.5About Bisacodyl*Diphenyl methane derivative ,Stimulant (irritant)Laxative**Mechanism of Action of Bisacodyl*Bisacodyl is a stimulant (irritant) laxative. It acts directly on the colonic mucosa-where it stimulates sensory nerve endings in the walls of the intestine and the rectum to produce parasympathetic reflexes resulting in increased peristaltic contractions of the colon and cause defecation.**Indications for Bisacodyl*1.Bowel evacuation in prior to radiological examinations *2.Constipation *3.Laxative in postoperative, ante partum, or postpartum care**Contra-indications of Bisacodyl*1.Hypersensitivity to Bisacodyl *2.Intestinal obstruction *3.Obstruction of the intestines due to loss of intestinal movement *4.Severe dehydration *5.Sudden abdominal conditions requiring surgery (appendicitis) *6.Sudden attacks of inflammatory bowel disease (ulcerative colitis or Crohn`s disease) *7.Anal fissure *8.Ulcerative proctitis
ABILAXINE 5mg 5 infantile supp.BISACODYLGLAXO SMITHKLINE3.2About Bisacodyl*Diphenyl methane derivative ,Stimulant (irritant)Laxative**Mechanism of Action of Bisacodyl*Bisacodyl is a stimulant (irritant) laxative. It acts directly on the colonic mucosa-where it stimulates sensory nerve endings in the walls of the intestine and the rectum to produce parasympathetic reflexes resulting in increased peristaltic contractions of the colon and cause defecation.**Indications for Bisacodyl*1.Bowel evacuation in prior to radiological examinations *2.Constipation *3.Laxative in postoperative, ante partum, or postpartum care**Contra-indications of Bisacodyl*1.Hypersensitivity to Bisacodyl *2.Intestinal obstruction *3.Obstruction of the intestines due to loss of intestinal movement *4.Severe dehydration *5.Sudden abdominal conditions requiring surgery (appendicitis) *6.Sudden attacks of inflammatory bowel disease (ulcerative colitis or Crohn`s disease) *7.Anal fissure *8.Ulcerative proctitis
ABIMOL 150mg/5ml 125ml syrupPARACETAMOL(ACETAMINOPHEN)GLAXO SMITHKLINEAntipyretic5About Paracetamol*Acetanilide derivative, Non narcotic Analgesic,Antipyretic.*Mechanism of Action of Paracetamol*Paracetamol has analgesic and antipyretic action. *It is more active on cyclo-oxygenase enzyme in brain. Peripherally it is a poor inhibitor of prostaglandin synthesis. *Analgesic action: Paracetamol raises the pain threshold and produces analgesic effect. *Antipyretic action: Paracetamol lowers fever by direct action on the thermoregulatory centre in the Hypothalamus and block the effects of endogenous pyrogen. *Indications for Paracetamol*1. To relieve pain and fever *2. Acute gout *3. Migraine *Interactions for Paracetamol*Cholestyramine: Reduces absorption of paracetamol. *Charcoal: Activated, administered immediately reduces absorption of paracetamol. *Domperidone and metochlopramide: Enhance absorption of paracetamol. *Alcohol: Chronic excessive ingestion of alcohol potentiates hepatotoxicity of paracetamol. *
ABIMOL 300mg 5 rectal supp.PARACETAMOL(ACETAMINOPHEN)GLAXO SMITHKLINEAntipyretic4.5About Paracetamol*Acetanilide derivative, Non narcotic Analgesic,Antipyretic.*Mechanism of Action of Paracetamol*Paracetamol has analgesic and antipyretic action. *It is more active on cyclo-oxygenase enzyme in brain. Peripherally it is a poor inhibitor of prostaglandin synthesis. *Analgesic action: Paracetamol raises the pain threshold and produces analgesic effect. *Antipyretic action: Paracetamol lowers fever by direct action on the thermoregulatory centre in the Hypothalamus and block the effects of endogenous pyrogen. *Indications for Paracetamol*1. To relieve pain and fever *2. Acute gout *3. Migraine *Interactions for Paracetamol*Cholestyramine: Reduces absorption of paracetamol. *Charcoal: Activated, administered immediately reduces absorption of paracetamol. *Domperidone and metochlopramide: Enhance absorption of paracetamol. *Alcohol: Chronic excessive ingestion of alcohol potentiates hepatotoxicity of paracetamol. *
ABIMOL 500 MG 20 TABLETSPARACETAMOL(ACETAMINOPHEN)GLAXO SMITHKLINEAntipyretic8mechanism:*It is thought paracetamol reduces fever by affecting an area of the brain that regulates our body temperature (the hypothalamic heat-regulating center).*Paracetamol is about as effective as aspirin or ibuprofen at relieving mild to moderate pain and fever, but unlike aspirin and ibuprofen it has no anti-inflammatory effect.
ABIMOL EXTRA 20tab.CAFFEINE-PARACETAMOL(ACETAMINOPHEN)GLAXO SMITHKLINE9mechanism:*It is thought paracetamol reduces fever by affecting an area of the brain that regulates our body temperature (the hypothalamic heat-regulating center).*Paracetamol is about as effective as aspirin or ibuprofen at relieving mild to moderate pain and fever, but unlike aspirin and ibuprofen it has no anti-inflammatory effect.*Caffeine is a mild stimulant that helps reduce fatigue. Caffeine is also thought to enhance the painkilling effect of paracetamol.**What is it used for?*Mild to moderate pain, such as headache, migraine, toothache, sore throat, muscular and rheumatic pain, nerve pain (neuralgia), backache (lumbago) and period pain.*Relieving aches, pains, sore throat and fever associated with colds and flu.***
ABIVIT-A 50.000 I.U.20 CAPVITAMIN AGLAXO SMITHKLINE3.75
ACTIFED 12 tab.PSEUDOEPHEDRINE--TRIPROLIDINEGLAXO SMITHKLINE5About Pseudoephedrine*Alpha/Beta Adrenergic Agonist, a phenethylamine derivative, A nasal decongestant.*Mechanism of Action of Pseudoephedrine*It is a nasal decongestant with alpha-2 agonistic action. It produces local vasoconstriction, reduces blood flow, and causes shrinkage of mucosa which provides relief of nasal congestion. It reduces oedema of the nasal mucosa, thus improving ventilation, drainage and nasal stuffiness.*About Triprolidine*First generation histamine H1 antagonist, Alkylamine derivative, Antihistamine.*Mechanism of Action of Triprolidine*Triprolidine hydrochloride exerts it`s action by acting as an H1 receptor antagonist. It antagonizes most of the pharmacological actions of Histamine and reduces allergic symptoms. It also has anticholinergic properties and reduces secretions
ACTIFED 120ml syrupPSEUDOEPHEDRINE--TRIPROLIDINEGLAXO SMITHKLINE5.5About Pseudoephedrine*Alpha/Beta Adrenergic Agonist, a phenethylamine derivative, A nasal decongestant.*Mechanism of Action of Pseudoephedrine*It is a nasal decongestant with alpha-2 agonistic action. It produces local vasoconstriction, reduces blood flow, and causes shrinkage of mucosa which provides relief of nasal congestion. It reduces oedema of the nasal mucosa, thus improving ventilation, drainage and nasal stuffiness.*About Triprolidine*First generation histamine H1 antagonist, Alkylamine derivative, Antihistamine.*Mechanism of Action of Triprolidine*Triprolidine hydrochloride exerts it`s action by acting as an H1 receptor antagonist. It antagonizes most of the pharmacological actions of Histamine and reduces allergic symptoms. It also has anticholinergic properties and reduces secretions
ACTIFED EXPECTORANT 120ml syrupGUAIFENESIN--PSEUDOEPHEDRINE--TRIPROLIDINEGLAXO SMITHKLINEAnti-Cough.Antitussive and expectorant6.25"Description *An expectorant that also has some muscle relaxing action*Mechanism of action Guaifenesin may act as an irritant to gastric vagal receptors, and recruit efferent parasympathetic reflexes that cause glandular exocytosis of a less viscous mucus mixture. Cough may be provoked. This combination may flush tenacious, congealed mucopurulent material from obstructed small airways and lead to a temporary improvement in dyspnea or the work of breathing."
ALTARGO 1% top.oint.RETAPAMULINGLAXO SMITHKLINE31.5"It s an antibiotic used in treatment of impetigo, small infected lacerations, abrasions and wounds that have sutured.*Use: Twice daily for five days.*Retapamulin is an antibiotic belonging to the ""pleuromutilin"""
AMBROXOL 15 mg/5ml syp.AMBROXOLGLAXO SMITHKLINE7.5"(Indications):*This medication is a mucolytic agent, prescribed for various respiratory diseases such as emphysema with bronchitis pneumoconiosis, chronic inflammatory pulmonary conditions, tracheobronchitis (respiratory tract inflammation), bronchiectasis, bronchitis with bronchospasm asthma. **(dosage) :* The recommended dose is 30-120 mg/day in 2-3 divided doses.**(Warnings and Precautions) : * Caution needed for pregnant and breastfeeding women.*"
AMBROXOL 30 mg 20 tab.AMBROXOLGLAXO SMITHKLINE5.5"(Indications):*This medication is a mucolytic agent, prescribed for various respiratory diseases such as emphysema with bronchitis pneumoconiosis, chronic inflammatory pulmonary conditions, tracheobronchitis (respiratory tract inflammation), bronchiectasis, bronchitis with bronchospasm asthma. **(dosage) :* The recommended dose is 30-120 mg/day in 2-3 divided doses.**(Warnings and Precautions) : * Caution needed for pregnant and breastfeeding women.*"
AMBROXOL 7.5mg/ml oral dropsAMBROXOLGLAXO SMITHKLINE5"(Indications):*This medication is a mucolytic agent, prescribed for various respiratory diseases such as emphysema with bronchitis pneumoconiosis, chronic inflammatory pulmonary conditions, tracheobronchitis (respiratory tract inflammation), bronchiectasis, bronchitis with bronchospasm asthma. **(dosage) :* The recommended dose is 30-120 mg/day in 2-3 divided doses.**(Warnings and Precautions) : * Caution needed for pregnant and breastfeeding women.*"
AMBROXOL 75mg S.R 10Caps.AMBROXOLGLAXO SMITHKLINE9.25"(Indications):*This medication is a mucolytic agent, prescribed for various respiratory diseases such as emphysema with bronchitis pneumoconiosis, chronic inflammatory pulmonary conditions, tracheobronchitis (respiratory tract inflammation), bronchiectasis, bronchitis with bronchospasm asthma. **(dosage) :* The recommended dose is 30-120 mg/day in 2-3 divided doses.**(Warnings and Precautions) : * Caution needed for pregnant and breastfeeding women.*"
ARIXTRA 10mg/0.8ml 10 S.C. injectionFONDAPARINUX SODIUMGLAXO SMITHKLINEAnticoagulant.Low MWT heparin Synthetic pentasaccharide1050"Mechanism of action *The antithrombotic activity of fondaparinux is the result of ATIII-mediated selective inhibition of Factor Xa. By selectively binding to ATIII, Fondaparinux potentiates (about 300 times) the neutralization of Factor Xa by ATIII. Neutralization of Factor Xa interrupts the blood coagulation cascade and thus inhibits thrombin formation and thrombus development. It is thought that fondaparinux is unlikely to induce thrombocytopenia via a heparin-induced thrombocytopenia (HIT)-like mechanism given its chemical structure (PMID 19825921). As a result, fondaparinux has been used as an alternative anticoagulant in heparin-induced thrombocytopenia (HIT) patients (PMID 19737996, 19432027, 18217156). However, it is important to note that rare cases of HIT have been reported in patients treated with fondaparinux"
ARIXTRA 2.5mg/0.5ml 10 S.C. injection.FONDAPARINUX SODIUMGLAXO SMITHKLINEAnticoagulant.Low MWT heparin Synthetic pentasaccharide546"Mechanism of action *The antithrombotic activity of fondaparinux is the result of ATIII-mediated selective inhibition of Factor Xa. By selectively binding to ATIII, Fondaparinux potentiates (about 300 times) the neutralization of Factor Xa by ATIII. Neutralization of Factor Xa interrupts the blood coagulation cascade and thus inhibits thrombin formation and thrombus development. It is thought that fondaparinux is unlikely to induce thrombocytopenia via a heparin-induced thrombocytopenia (HIT)-like mechanism given its chemical structure (PMID 19825921). As a result, fondaparinux has been used as an alternative anticoagulant in heparin-induced thrombocytopenia (HIT) patients (PMID 19737996, 19432027, 18217156). However, it is important to note that rare cases of HIT have been reported in patients treated with fondaparinux"
ARIXTRA 5mg/0.4ml 10 S.C. injectionFONDAPARINUX SODIUMGLAXO SMITHKLINEAnticoagulant.Low MWT heparin Synthetic pentasaccharide980"Mechanism of action *The antithrombotic activity of fondaparinux is the result of ATIII-mediated selective inhibition of Factor Xa. By selectively binding to ATIII, Fondaparinux potentiates (about 300 times) the neutralization of Factor Xa by ATIII. Neutralization of Factor Xa interrupts the blood coagulation cascade and thus inhibits thrombin formation and thrombus development. It is thought that fondaparinux is unlikely to induce thrombocytopenia via a heparin-induced thrombocytopenia (HIT)-like mechanism given its chemical structure (PMID 19825921). As a result, fondaparinux has been used as an alternative anticoagulant in heparin-induced thrombocytopenia (HIT) patients (PMID 19737996, 19432027, 18217156). However, it is important to note that rare cases of HIT have been reported in patients treated with fondaparinux"
ARIXTRA 7.5mg/0.6ml 10 S.C injectionFONDAPARINUX SODIUMGLAXO SMITHKLINEAnticoagulant.Low MWT heparin Synthetic pentasaccharide1050"Mechanism of action *The antithrombotic activity of fondaparinux is the result of ATIII-mediated selective inhibition of Factor Xa. By selectively binding to ATIII, Fondaparinux potentiates (about 300 times) the neutralization of Factor Xa by ATIII. Neutralization of Factor Xa interrupts the blood coagulation cascade and thus inhibits thrombin formation and thrombus development. It is thought that fondaparinux is unlikely to induce thrombocytopenia via a heparin-induced thrombocytopenia (HIT)-like mechanism given its chemical structure (PMID 19825921). As a result, fondaparinux has been used as an alternative anticoagulant in heparin-induced thrombocytopenia (HIT) patients (PMID 19737996, 19432027, 18217156). However, it is important to note that rare cases of HIT have been reported in patients treated with fondaparinux"
AUGMENTIN 6.25mg/ml infant dropsAMOXICILLIN -- CLAVULANIC ACIDGLAXO SMITHKLINEPenicillins.Penicillin with B-lactamase inhbitor29Amoxicillin is an analog of ampicillin, derived from the basic penicillin nucleus, 6-aminopenicillanic acid*Clavulanic acid is produced by the fermentation of Streptomyces clavuligerus. It is a beta-lactam structurally related to the penicillins and possesses the ability to inactivate some beta-lactamases by blocking the active sites of these enzymes.*Lower Respiratory Tract Infections - caused by beta-lactamase-producing isolates of Haemophilus influenzae and Moraxella catarrhalis.**Acute Bacterial Otitis Media - caused by beta-lactamase-producing isolates of H. influenzae and M. catarrhalis.**Sinusitis - caused by beta-lactamase-producing isolates of H. influenzae and M. catarrhalis.**Skin and Skin Structure Infections - caused by beta-lactamase-producing isolates of Staphylococcus aureus, Escherichia coli, and Klebsiella species.**Urinary Tract Infections - caused by beta-lactamase-producing isolates of E. coli, Klebsiella species, and Enterobacter species.
AUGMENTIN DUO 228mg/5ml 70ml susp.AMOXICILLIN -- CLAVULANIC ACIDGLAXO SMITHKLINEPenicillins.Penicillin with B-lactamase inhbitor47Amoxicillin is an analog of ampicillin, derived from the basic penicillin nucleus, 6-aminopenicillanic acid*Clavulanic acid is produced by the fermentation of Streptomyces clavuligerus. It is a beta-lactam structurally related to the penicillins and possesses the ability to inactivate some beta-lactamases by blocking the active sites of these enzymes.*Lower Respiratory Tract Infections - caused by beta-lactamase-producing isolates of Haemophilus influenzae and Moraxella catarrhalis.**Acute Bacterial Otitis Media - caused by beta-lactamase-producing isolates of H. influenzae and M. catarrhalis.**Sinusitis - caused by beta-lactamase-producing isolates of H. influenzae and M. catarrhalis.**Skin and Skin Structure Infections - caused by beta-lactamase-producing isolates of Staphylococcus aureus, Escherichia coli, and Klebsiella species.**Urinary Tract Infections - caused by beta-lactamase-producing isolates of E. coli, Klebsiella species, and Enterobacter species.
AVAMYS nasal sprayFLUTICASONE FUROATEGLAXO SMITHKLINEBronchodilator.Anti-inflammatory.glucocorticoid steroid60About Fluticasone*Synthetic topical glucocorticoid, Anti inflammatory and antipruritic in corticosteroid-responsive dermatoses- atopic dermatitis.**Mechanism of Action of Fluticasone*It reduces prostaglandin synthesis by inhibiting cyclo oxygenase enzymes both COX1 and COX2.In higher doses it reduces the thromboxane A2 synthesis by COX1 inhibition. So platelet aggregation is inhibited by this drug. After topical application in the case of ophthalmic preparation it prevents miosis by reducing ocular prostaglandins synthesis. It is a phenylalkalonic acid derivative Non Steroidal Anti Inflammatory Drug.
BACTROBAN 2% topical cream 15 GMMUPIROCINGLAXO SMITHKLINEAnti-Bacterial.Protein Synthesis Inhibitor27About Mupirocin*A naturally antibiotic isolated from Pseudomonas fluorescens, Antibiotic.**Mechanism of Action of Mupirocin*Mupirocin exerts its action by reversibly binding to isoleucyl transfer RNA synthetase and inhibits the enzyme activity. This enzyme is necessary for the synthesis of proteins in the bacteria. Inhibition of isoleucyl transfer RNA synthetase results in inhibition of protein synthesis and produce microbicidal action. It is more active against gram positive bacteria as compared to gram negative bacteria.**Indications for Mupirocin*Bacterial skin infections: *1. Impetigo *2. Infected eczema *3. Folliculitis *4. Eradication of nasal colonization of Methicillin resistant S.aureus *
BACTROBAN 2% topical oint. 15 GMMUPIROCINGLAXO SMITHKLINEAnti-Bacterial.Protein Synthesis Inhibitor27About Mupirocin*A naturally antibiotic isolated from Pseudomonas fluorescens, Antibiotic.**Mechanism of Action of Mupirocin*Mupirocin exerts its action by reversibly binding to isoleucyl transfer RNA synthetase and inhibits the enzyme activity. This enzyme is necessary for the synthesis of proteins in the bacteria. Inhibition of isoleucyl transfer RNA synthetase results in inhibition of protein synthesis and produce microbicidal action. It is more active against gram positive bacteria as compared to gram negative bacteria.**Indications for Mupirocin*Bacterial skin infections: *1. Impetigo *2. Infected eczema *3. Folliculitis *4. Eradication of nasal colonization of Methicillin resistant S.aureus *
BETNOVATE 0.1 % scalp application 30 MLBETAMETHASONEGLAXO SMITHKLINE12About Betamethasone*Potent glucocorticoid, Anti-inflammatory, immunosuppressent.**Mechanism of Action of Betamethasone*The drug exerts it`s pharmacological action by penetrating and binding to cytoplasmic receptor protein and causes a structural change in steroid receptor complex. This structural change allows it`s migration in to the nucleus and then binding to specific sites on the DNA which leads to transcription of specific m-RNA and which ultimately regulates protein synthesis. It exerts highly selective glucocorticoid action. It stimulates the enzymes needed to decrease the inflammatory response. **Indications for Betamethasone*1.Inflammatory conditions *2.Allergic reactions *3.Shock *4.Anaphylaxis *5.Intra-articular and soft tissue inflammation *6.Asthma *7.Rheumatoid arthritis *8.Adrenal insufficiency *9.Tuberculous meningitis *10.Respiratory diseases *11.Malignancies *12.Cerebral oedema *13.Collagen diseases *14.Addison`s disease *15.Simmond`s disease *
CALMEPAM 1.5mg 30tab.BROMAZEPAMGLAXO SMITHKLINEpsychiatric.Anxiolytics-hypnotics10.8About Bromazepam*Benzodiazepine derivative,Anxiolytic,Sedative,Hypnotic,Skeletal muscle relaxant**Mechanism of Action of Bromazepam*Bromazepam binds to the GABA receptor GABAA. These will facilitates GABA mediated chloride channel opening and produce hyperpolarisation.This will produce an increase in the concentration of inhibitory neurotransmitter GABA and chloride ions and decreases firing rate of neurons.These alter normal excitatory functions of the body.**Indications for Bromazepam*1.Anxiety *2.Preanaesthetic medication *3.Epigastric pain *4.Hypertension *5.Insomnia *Interactions for Bromazepam*Alcohol and other CNS depressants--Enhanced CNS effect *Cemetidine,Disulfiram,Fluoxetine,Isoniazid,Ketoconazole,Propranalol,Propoxyphene, *Valproic Acid: Bromazepam activity enhanced *Digoxin,Imipiramine&Desipramine:Enhanced activity of these drugs *Levodopa:Decrease in antiparkinsonism efficacy
CALMEPAM 3mg 20 tab.BROMAZEPAMGLAXO SMITHKLINEpsychiatric.Anxiolytics-hypnotics8.6About Bromazepam*Benzodiazepine derivative,Anxiolytic,Sedative,Hypnotic,Skeletal muscle relaxant**Mechanism of Action of Bromazepam*Bromazepam binds to the GABA receptor GABAA. These will facilitates GABA mediated chloride channel opening and produce hyperpolarisation.This will produce an increase in the concentration of inhibitory neurotransmitter GABA and chloride ions and decreases firing rate of neurons.These alter normal excitatory functions of the body.**Indications for Bromazepam*1.Anxiety *2.Preanaesthetic medication *3.Epigastric pain *4.Hypertension *5.Insomnia *Interactions for Bromazepam*Alcohol and other CNS depressants--Enhanced CNS effect *Cemetidine,Disulfiram,Fluoxetine,Isoniazid,Ketoconazole,Propranalol,Propoxyphene, *Valproic Acid: Bromazepam activity enhanced *Digoxin,Imipiramine&Desipramine:Enhanced activity of these drugs *Levodopa:Decrease in antiparkinsonism efficacy
CEPOREX 1 GM 8 tabletsCEFALEXINGLAXO SMITHKLINEAntibiotic.cephalosporin.First-generation30.75About Cefalexin*A first-generation cephalosporin antibiotic.**Mechanism of Action *Cephalexin is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cephalexin inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cephalexin **Indications for Cefalexin*1.Respiratory tract infections *2.Urinary tract infections *3.Surgical prophylaxis *4.Skin infections` *5.Joint & bone infections *6.Otitis media` *7.Reproductive tract infections` **Contra-indications*1.Hypersensitivity to cephalosporins *2.Porphyria *3.Neuromuscular disorders.
CEPOREX 125mg /5ml 60ml syrupCEFALEXINGLAXO SMITHKLINEAntibiotic.cephalosporin.First-generation8About Cefalexin*A first-generation cephalosporin antibiotic.**Mechanism of Action *Cephalexin is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cephalexin inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cephalexin **Indications for Cefalexin*1.Respiratory tract infections *2.Urinary tract infections *3.Surgical prophylaxis *4.Skin infections` *5.Joint & bone infections *6.Otitis media` *7.Reproductive tract infections` **Contra-indications*1.Hypersensitivity to cephalosporins *2.Porphyria *3.Neuromuscular disorders.
CEPOREX 250 mg 12 tabletsCEFALEXINGLAXO SMITHKLINEAntibiotic.cephalosporin.First-generation12.75About Cefalexin*A first-generation cephalosporin antibiotic.**Mechanism of Action *Cephalexin is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cephalexin inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cephalexin **Indications for Cefalexin*1.Respiratory tract infections *2.Urinary tract infections *3.Surgical prophylaxis *4.Skin infections` *5.Joint & bone infections *6.Otitis media` *7.Reproductive tract infections` **Contra-indications*1.Hypersensitivity to cephalosporins *2.Porphyria *3.Neuromuscular disorders.
CEPOREX 250 mg/5ml 60ml syrupCEFALEXINGLAXO SMITHKLINEAntibiotic.cephalosporin.First-generation18About Cefalexin*A first-generation cephalosporin antibiotic.**Mechanism of Action *Cephalexin is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cephalexin inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cephalexin **Indications for Cefalexin*1.Respiratory tract infections *2.Urinary tract infections *3.Surgical prophylaxis *4.Skin infections` *5.Joint & bone infections *6.Otitis media` *7.Reproductive tract infections` **Contra-indications*1.Hypersensitivity to cephalosporins *2.Porphyria *3.Neuromuscular disorders.
CEPOREX 500mg 12 tabletsCEFALEXINGLAXO SMITHKLINEAntibiotic.cephalosporin.First-generation27About Cefalexin*A first-generation cephalosporin antibiotic.**Mechanism of Action *Cephalexin is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cephalexin inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cephalexin **Indications for Cefalexin*1.Respiratory tract infections *2.Urinary tract infections *3.Surgical prophylaxis *4.Skin infections` *5.Joint & bone infections *6.Otitis media` *7.Reproductive tract infections` **Contra-indications*1.Hypersensitivity to cephalosporins *2.Porphyria *3.Neuromuscular disorders.
CERVARIX 0.5ml vaccineHUMAN PAPILLOMAVIRUS VACCINEGLAXO SMITHKLINE300
CUTIVATE 0.05% top. cream 15 GMFLUTICASONE PROPIONATEGLAXO SMITHKLINEAnti-inflammatory.glucocorticoid.bronchodilator17.25"Description *Fluticasone propionate, a medium-potency synthetic corticosteroid, is used topically to relieve inflammatory and pruritic symptoms of dermatoses and psoriasis, intranasally to manage symptoms of allergic and non-allergic rhinitis, and orally for the treatment of asthma. Fluticasone proprionate is marketed under several different brand names such as Flonaseï؟½. Fluticasone propionate is also available as a combination product of azelastine hydrochloride and fluticasone propionate called Dymistaï؟½. Dymistaï؟½ is indicated in patients over 12 years old for symptomatic relief of seasonal allergic rhinitis.**Indication * is used topically to relieve inflammatory and pruritic symptoms of dermatoses and psoriasis, intranasally to manage symptoms of allergic and non-allergic rhinitis, and orally for the maintenance treatment of asthma as prophylactic therapy and for patients requiring oral corticosteroid therapy for asthma."
DARAPRIM 25mg 30tab.PYRIMETHAMINEGLAXO SMITHKLINE11About Pyrimethamine*Folic acid antagonist, Pyrimidine derivative, Antiprotozoal, Antimalarial.*Mechanism of Action of Pyrimethamine*Pyrimethamine binds to dihydrofolate reductase enzyme and inhibits the reduction of Dihydrofolic acid (DHFA) to Tetra hydrofolic acid (THFA) .This will interfere the synthesis of folic acid in malarial parasite.
DELAY-TIAZEM SR 120 mg 10 Caps.DILTIAZEMGLAXO SMITHKLINEAntihypertensive.Nonselective calcium channel blocker11.8About Diltiazem*A Benzothiazepine derivative, Calcium channel blocker, Anti hypertensive, anti-anginal, class IV antiarrhythmic.**Mechanism of Action of Diltiazem*Diltiazem is a Benzothiazepine- Ca channel blocker. It exerts it`s antianginal, antihypertensive, antiarrythmic actions through blocking the influx of Ca ions through voltage gated L-type Ca channels to the peripheral vascular smooth muscle cells, Coronary smooth muscle cells and to the myocardial cells. Thus causes dilatation of vascular endothelium, decrease peripheral resistance, and decrease BP in hypertensive individuals. **Indications for Diltiazem*1. Hypertension *2. Prinzmetal`s angina *3. Stable angina
DELAY-TIAZEM SR 180 mg 10Caps.DILTIAZEMGLAXO SMITHKLINEAntihypertensive.Nonselective calcium channel blocker15.95About Diltiazem*A Benzothiazepine derivative, Calcium channel blocker, Anti hypertensive, anti-anginal, class IV antiarrhythmic.**Mechanism of Action of Diltiazem*Diltiazem is a Benzothiazepine- Ca channel blocker. It exerts it`s antianginal, antihypertensive, antiarrythmic actions through blocking the influx of Ca ions through voltage gated L-type Ca channels to the peripheral vascular smooth muscle cells, Coronary smooth muscle cells and to the myocardial cells. Thus causes dilatation of vascular endothelium, decrease peripheral resistance, and decrease BP in hypertensive individuals. **Indications for Diltiazem*1. Hypertension *2. Prinzmetal`s angina *3. Stable angina
DELAY-TIAZEM SR 90 mg 10Caps.DILTIAZEMGLAXO SMITHKLINEAntihypertensive.Nonselective calcium channel blocker9.5About Diltiazem*A Benzothiazepine derivative, Calcium channel blocker, Anti hypertensive, anti-anginal, class IV antiarrhythmic.**Mechanism of Action of Diltiazem*Diltiazem is a Benzothiazepine- Ca channel blocker. It exerts it`s antianginal, antihypertensive, antiarrythmic actions through blocking the influx of Ca ions through voltage gated L-type Ca channels to the peripheral vascular smooth muscle cells, Coronary smooth muscle cells and to the myocardial cells. Thus causes dilatation of vascular endothelium, decrease peripheral resistance, and decrease BP in hypertensive individuals. **Indications for Diltiazem*1. Hypertension *2. Prinzmetal`s angina *3. Stable angina
DERMOVATE 0.05 % ointment 25 GMCLOBETASOL PROPIONATEGLAXO SMITHKLINE15.75About Clobetasol propionate*Topical adenocorticoid, Anti inflammatory.**Mechanism of Action of Clobetasol propionate*Clobetasol is a topical corticosteroid. It induces peptide Lipocortins which inhibit the enzyme Phospholipase A2. Phospholipase A2 is essential for the conversion of membrane phospholipids to Arachidonic acid. From this Arachidonic acid inflammatory mediators like prostaglandins, kinins, histamine, liposomal enzymes and the complement system are produced. By inhibiting Phospholipase A2 inflammatory mediators are not released. It also inhibits the migration of macrophages and leukocytes to the inflamed area by its vasoconstrictive properties. Corticosteroids also inhibit capillary production, collagen deposition and keloid (scar) formation. **Indications for Clobetasol propionate*1.Skin disorders *2.Eczema *3.Psoriasis *4.Alopecia areata *5.Inflammation of corticosteroid dermatoses (secondary infected) *6.Chronic discoid lupus Erythematosus
DERMOVATE 0.05% top. cream 25 GMCLOBETASOL PROPIONATEGLAXO SMITHKLINE15.75About Clobetasol propionate*Topical adenocorticoid, Anti inflammatory.**Mechanism of Action of Clobetasol propionate*Clobetasol is a topical corticosteroid. It induces peptide Lipocortins which inhibit the enzyme Phospholipase A2. Phospholipase A2 is essential for the conversion of membrane phospholipids to Arachidonic acid. From this Arachidonic acid inflammatory mediators like prostaglandins, kinins, histamine, liposomal enzymes and the complement system are produced. By inhibiting Phospholipase A2 inflammatory mediators are not released. It also inhibits the migration of macrophages and leukocytes to the inflamed area by its vasoconstrictive properties. Corticosteroids also inhibit capillary production, collagen deposition and keloid (scar) formation. **Indications for Clobetasol propionate*1.Skin disorders *2.Eczema *3.Psoriasis *4.Alopecia areata *5.Inflammation of corticosteroid dermatoses (secondary infected) *6.Chronic discoid lupus Erythematosus
ENGERIX B (PEDIATRIC)I.M. injection 10 mcg/0.5ml vialVACCINE HEPATITIS BGLAXO SMITHKLINE11
EUMOVATE 0.05gm/100gm top. cream 15 GMCLOBETASONEGLAXO SMITHKLINE8.5About Clobetasone *Corticosteroid, ophthalmic anti inflammatory.**Mechanism of Action of Clobetasone*Clobetasone is a topical corticosteroid. It induces peptide Lipocortins which inhibit the enzyme Phospholipase A2. Phospholipase A2 is essential for the conversion of membrane phospholipids to Arachidonic acid. From this Arachidonic acid inflammatory mediators like prostaglandins, kinins, histamine, liposomal enzymes and the complement system are produced. By inhibiting Phospholipase A2 inflammatory mediators are not released. It also inhibits the migration of macrophages and leukocytes to the inflamed area by its vasoconstrictive properties. Corticosteroids also inhibit capillary production, collagen deposition and keloid (scar) formation on the inflamed area. Thus inhibiting inflammatory mediators and other actions Clobetasone are used for anti-inflammatory conditions.
FLIXONASE AQUEOUS 50 mcg/metered spray doseFLUTICASONE PROPIONATEGLAXO SMITHKLINEAnti-inflammatory.glucocorticoid.bronchodilator49.5"Description *Fluticasone propionate, a medium-potency synthetic corticosteroid, is used topically to relieve inflammatory and pruritic symptoms of dermatoses and psoriasis, intranasally to manage symptoms of allergic and non-allergic rhinitis, and orally for the treatment of asthma. Fluticasone proprionate is marketed under several different brand names such as Flonaseï؟½. Fluticasone propionate is also available as a combination product of azelastine hydrochloride and fluticasone propionate called Dymistaï؟½. Dymistaï؟½ is indicated in patients over 12 years old for symptomatic relief of seasonal allergic rhinitis.**Indication * is used topically to relieve inflammatory and pruritic symptoms of dermatoses and psoriasis, intranasally to manage symptoms of allergic and non-allergic rhinitis, and orally for the maintenance treatment of asthma as prophylactic therapy and for patients requiring oral corticosteroid therapy for asthma."
FLIXOTIDE DISKUS 100mcg/dose accuhalerFLUTICASONE PROPIONATEGLAXO SMITHKLINEAnti-inflammatory.glucocorticoid.bronchodilator40"Description *Fluticasone propionate, a medium-potency synthetic corticosteroid, is used topically to relieve inflammatory and pruritic symptoms of dermatoses and psoriasis, intranasally to manage symptoms of allergic and non-allergic rhinitis, and orally for the treatment of asthma. Fluticasone proprionate is marketed under several different brand names such as Flonaseï؟½. Fluticasone propionate is also available as a combination product of azelastine hydrochloride and fluticasone propionate called Dymistaï؟½. Dymistaï؟½ is indicated in patients over 12 years old for symptomatic relief of seasonal allergic rhinitis.**Indication * is used topically to relieve inflammatory and pruritic symptoms of dermatoses and psoriasis, intranasally to manage symptoms of allergic and non-allergic rhinitis, and orally for the maintenance treatment of asthma as prophylactic therapy and for patients requiring oral corticosteroid therapy for asthma."
FLIXOTIDE DISKUS 250 mcg/dose inhalerFLUTICASONE PROPIONATEGLAXO SMITHKLINEAnti-inflammatory.glucocorticoid.bronchodilator85"Description *Fluticasone propionate, a medium-potency synthetic corticosteroid, is used topically to relieve inflammatory and pruritic symptoms of dermatoses and psoriasis, intranasally to manage symptoms of allergic and non-allergic rhinitis, and orally for the treatment of asthma. Fluticasone proprionate is marketed under several different brand names such as Flonaseï؟½. Fluticasone propionate is also available as a combination product of azelastine hydrochloride and fluticasone propionate called Dymistaï؟½. Dymistaï؟½ is indicated in patients over 12 years old for symptomatic relief of seasonal allergic rhinitis.**Indication * is used topically to relieve inflammatory and pruritic symptoms of dermatoses and psoriasis, intranasally to manage symptoms of allergic and non-allergic rhinitis, and orally for the maintenance treatment of asthma as prophylactic therapy and for patients requiring oral corticosteroid therapy for asthma."
FLIXOTIDE DISKUS 50mcg/dose accuhalerFLUTICASONE PROPIONATEGLAXO SMITHKLINEAnti-inflammatory.glucocorticoid.bronchodilator36"Description *Fluticasone propionate, a medium-potency synthetic corticosteroid, is used topically to relieve inflammatory and pruritic symptoms of dermatoses and psoriasis, intranasally to manage symptoms of allergic and non-allergic rhinitis, and orally for the treatment of asthma. Fluticasone proprionate is marketed under several different brand names such as Flonaseï؟½. Fluticasone propionate is also available as a combination product of azelastine hydrochloride and fluticasone propionate called Dymistaï؟½. Dymistaï؟½ is indicated in patients over 12 years old for symptomatic relief of seasonal allergic rhinitis.**Indication * is used topically to relieve inflammatory and pruritic symptoms of dermatoses and psoriasis, intranasally to manage symptoms of allergic and non-allergic rhinitis, and orally for the maintenance treatment of asthma as prophylactic therapy and for patients requiring oral corticosteroid therapy for asthma."
FLIXOTIDE EVOHALER 125mcg/actuation inhalerFLUTICASONE PROPIONATEGLAXO SMITHKLINEAnti-inflammatory.glucocorticoid.bronchodilator60"Description *Fluticasone propionate, a medium-potency synthetic corticosteroid, is used topically to relieve inflammatory and pruritic symptoms of dermatoses and psoriasis, intranasally to manage symptoms of allergic and non-allergic rhinitis, and orally for the treatment of asthma. Fluticasone proprionate is marketed under several different brand names such as Flonaseï؟½. Fluticasone propionate is also available as a combination product of azelastine hydrochloride and fluticasone propionate called Dymistaï؟½. Dymistaï؟½ is indicated in patients over 12 years old for symptomatic relief of seasonal allergic rhinitis.**Indication * is used topically to relieve inflammatory and pruritic symptoms of dermatoses and psoriasis, intranasally to manage symptoms of allergic and non-allergic rhinitis, and orally for the maintenance treatment of asthma as prophylactic therapy and for patients requiring oral corticosteroid therapy for asthma."
FLIXOTIDE EVOHALER 50mcg/actuation inhalerFLUTICASONE PROPIONATEGLAXO SMITHKLINEAnti-inflammatory.glucocorticoid.bronchodilator47"Description *Fluticasone propionate, a medium-potency synthetic corticosteroid, is used topically to relieve inflammatory and pruritic symptoms of dermatoses and psoriasis, intranasally to manage symptoms of allergic and non-allergic rhinitis, and orally for the treatment of asthma. Fluticasone proprionate is marketed under several different brand names such as Flonaseï؟½. Fluticasone propionate is also available as a combination product of azelastine hydrochloride and fluticasone propionate called Dymistaï؟½. Dymistaï؟½ is indicated in patients over 12 years old for symptomatic relief of seasonal allergic rhinitis.**Indication * is used topically to relieve inflammatory and pruritic symptoms of dermatoses and psoriasis, intranasally to manage symptoms of allergic and non-allergic rhinitis, and orally for the maintenance treatment of asthma as prophylactic therapy and for patients requiring oral corticosteroid therapy for asthma."
FLUARIX 15 mcg/0.5ml I.M. or S.C. injection in prefilled syringe.VACCINE INFLUENZAGLAXO SMITHKLINE32
FLUREST N 20 TABS.CHLORPHENIRAMINE -- PARACETAMOL(ACETAMINOPHEN) -- PHENYLEPHRINEGLAXO SMITHKLINE9Flurest is a well-balanced combination of:*Paracetamol: Antipyretic and analgesic.*Phenylephrine HCL: A potent vasoconstrictor equal to ephedrine with minimal side effects.*Chlorpheniramine maleate: Antihistaminic of short duration of action with mild sedative effect.**Indications:*Flurest is an effective analgesic, decongestant, antihistaminic and anticatarrhal agent. When used early Flurest can give relief or even abort conditions associated with nasal congestion and hypersecretion such as: Influenza, Cold attacks, Spring catarrh and nasal sensitivity and other nasal congestive inflammatory conditions.
FLUSTOP 20 tab. (CANCELLED)CAFFEINE -- CHLORPHENIRAMINE -- PARACETAMOL(ACETAMINOPHEN) -- PSEUDOEPHEDRINEGLAXO SMITHKLINE4.2"Description *A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma.*Indication For the treatment of rhinitis, urticaria, allergy, common cold, asthma and hay fever.*Pharmacodynamics In allergic reactions an allergen interacts with and cross-links surface IgE antibodies on mast cells and basophils. Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell-degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. Once released, histamine can react with local or widespread tissues through histamine receptors. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Chlorpheniramine, is a histamine H1 antagonist (or more correctly, an inverse histamine agonist) of the alkylamine class."
FORTUM 1gm vial.CEFTAZIDIMEGLAXO SMITHKLINEAntibiotic.cephalosporin.third-generation56.25About Ceftazidime*Third Generation Cephalosporin antibiotic, Parenteral antibiotic.**Mechanism of Action of Ceftazidime*Ceftazidime is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Ceftazidime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Ceftazidime.It is more active against pseudomonas.**Indications for Ceftazidime*1.Febrile neutropenic patients with haematological malignancies *2.Burn infections *3.Respiratory tract infections *4.Urinogenital tract infections *5.Bone & Joint infections *6.Septicemia *7.CNS infections *8.Skin & wound infections *9.Meningitis.
FORTUM 250 mg vialCEFTAZIDIMEGLAXO SMITHKLINEAntibiotic.cephalosporin.third-generation18About Ceftazidime*Third Generation Cephalosporin antibiotic, Parenteral antibiotic.**Mechanism of Action of Ceftazidime*Ceftazidime is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Ceftazidime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Ceftazidime.It is more active against pseudomonas.**Indications for Ceftazidime*1.Febrile neutropenic patients with haematological malignancies *2.Burn infections *3.Respiratory tract infections *4.Urinogenital tract infections *5.Bone & Joint infections *6.Septicemia *7.CNS infections *8.Skin & wound infections *9.Meningitis.
FORTUM 500mg vial.CEFTAZIDIMEGLAXO SMITHKLINEAntibiotic.cephalosporin.third-generation34.25About Ceftazidime*Third Generation Cephalosporin antibiotic, Parenteral antibiotic.**Mechanism of Action of Ceftazidime*Ceftazidime is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Ceftazidime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Ceftazidime.It is more active against pseudomonas.**Indications for Ceftazidime*1.Febrile neutropenic patients with haematological malignancies *2.Burn infections *3.Respiratory tract infections *4.Urinogenital tract infections *5.Bone & Joint infections *6.Septicemia *7.CNS infections *8.Skin & wound infections *9.Meningitis.
FUNGRYL 15 spray solutionECONAZOLEGLAXO SMITHKLINEantifungals.Imidazoles13About Econazole*Synthetic Imidazole derivative, Antifungal.*Mechanism of Action of Econazole**Econazole exerts its effects by altering cellular membrane and interfering with cellular enzymes.It is active against many fungi, dermatophytes and yeasts as well as some gram positive bacteria.**Indications for Econazole*1.Cutaneous candidiasis *2.Tinea pedis *3.Tinea cruris *4.Tinea versicolor **Typical Dosage for Econazole*Cutaneous candidiasis: Gently rub sufficient quantity to the affected area 2 times daily. *Tinea infection:Gently rub in to the affected area once daily.
FUNGRYL 1% topical cream 15 GMECONAZOLEGLAXO SMITHKLINEantifungals.Imidazoles5.5About Econazole*Synthetic Imidazole derivative, Antifungal.*Mechanism of Action of Econazole**Econazole exerts its effects by altering cellular membrane and interfering with cellular enzymes.It is active against many fungi, dermatophytes and yeasts as well as some gram positive bacteria.**Indications for Econazole*1.Cutaneous candidiasis *2.Tinea pedis *3.Tinea cruris *4.Tinea versicolor **Typical Dosage for Econazole*Cutaneous candidiasis: Gently rub sufficient quantity to the affected area 2 times daily. *Tinea infection:Gently rub in to the affected area once daily.
GLYCERIN ADULT 5 SUPP. (GLAXO)GLYCERINGLAXO SMITHKLINE5Mechanism of Action of Glycerine*Glycerine is a sweet clear viscous liquid with dehydrating property. It produces a warm sensation and irritates mucous membranes. When used as a suppository and applied to anal canal it induces evacuation. Glycerine soothes the irritated skin so it is used as a component of cough mixtures. When a 50% solution of Glycerine in water is applied to dry and chapped skin it acts as an emollient. When used a 10% solution I.V. it reduces intraocular or intracranial pressure. When used as a diuretic it significantly increases the osmolality of plasma and tubular fluid. It is pharmacologically inert and freely filtered at glomerulus and undergoes limited reabsorption by renal tubule and acts as osmotic diuretic.
GLYCERIN INFANTILE 10 SUPP. (GLAXO)GLYCERINGLAXO SMITHKLINE5Mechanism of Action of Glycerine*Glycerine is a sweet clear viscous liquid with dehydrating property. It produces a warm sensation and irritates mucous membranes. When used as a suppository and applied to anal canal it induces evacuation. Glycerine soothes the irritated skin so it is used as a component of cough mixtures. When a 50% solution of Glycerine in water is applied to dry and chapped skin it acts as an emollient. When used a 10% solution I.V. it reduces intraocular or intracranial pressure. When used as a diuretic it significantly increases the osmolality of plasma and tubular fluid. It is pharmacologically inert and freely filtered at glomerulus and undergoes limited reabsorption by renal tubule and acts as osmotic diuretic.
GYNORYL 1% vag.cream 30 GMECONAZOLEGLAXO SMITHKLINEantifungals.Imidazoles8About Econazole*Synthetic Imidazole derivative, Antifungal.*Mechanism of Action of Econazole**Econazole exerts its effects by altering cellular membrane and interfering with cellular enzymes.It is active against many fungi, dermatophytes and yeasts as well as some gram positive bacteria.**Indications for Econazole*1.Cutaneous candidiasis *2.Tinea pedis *3.Tinea cruris *4.Tinea versicolor **Typical Dosage for Econazole*Cutaneous candidiasis: Gently rub sufficient quantity to the affected area 2 times daily. *Tinea infection:Gently rub in to the affected area once daily.
GYNORYL 150mg 3 vag.supp.ECONAZOLEGLAXO SMITHKLINEantifungals.Imidazoles6.6About Econazole*Synthetic Imidazole derivative, Antifungal.*Mechanism of Action of Econazole**Econazole exerts its effects by altering cellular membrane and interfering with cellular enzymes.It is active against many fungi, dermatophytes and yeasts as well as some gram positive bacteria.**Indications for Econazole*1.Cutaneous candidiasis *2.Tinea pedis *3.Tinea cruris *4.Tinea versicolor **Typical Dosage for Econazole*Cutaneous candidiasis: Gently rub sufficient quantity to the affected area 2 times daily. *Tinea infection:Gently rub in to the affected area once daily.
GYNORYL 50mg 5 vag.ovulesECONAZOLEGLAXO SMITHKLINEantifungals.Imidazoles6.2About Econazole*Synthetic Imidazole derivative, Antifungal.*Mechanism of Action of Econazole**Econazole exerts its effects by altering cellular membrane and interfering with cellular enzymes.It is active against many fungi, dermatophytes and yeasts as well as some gram positive bacteria.**Indications for Econazole*1.Cutaneous candidiasis *2.Tinea pedis *3.Tinea cruris *4.Tinea versicolor **Typical Dosage for Econazole*Cutaneous candidiasis: Gently rub sufficient quantity to the affected area 2 times daily. *Tinea infection:Gently rub in to the affected area once daily.
HAEMOTON 28 soft gelatin Caps.COPPER -- FERROUS FUMARATE -- FOLIC ACID -- MANGANESE -- VITAMIN B12 -- VITAMIN CGLAXO SMITHKLINEAnemia.Iron Supplement16
HEPSERA 10mg 30tab.ADEFOVIRGLAXO SMITHKLINEAnti-Viral.Nucleoside520About Adefovir*Antiretroviral Agent, Reverse Transcriptase Inhibitor (Nucleoside)*Mechanism of Action of Adefovir*Adefovir undergoes phosphorylation in the presence of cellular kinase enzyme to Adefovir diphosphate. This Adefovir diphosphate competitively inhibits HBV DNA polymerase and reverse transcriptase enzyme by competing with nucleoside adenosine triphosphate and inhibits DNA synthesis.*Indications for Adefovir*1.Hepatitis B infection
IBIDROXIL 1 GM 8 F.C. TABS.CEFADROXILGLAXO SMITHKLINEAntibiotic.cephalosporin.First-generation29About Cefadroxil*First Generation Cephalosporin, para-hydroxy derivative of cefalexin, Oral broad-spectrum antibiotic**Mechanism of Action *Cefadroxil is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefadroxil inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefadroxil **Indications for Cefadroxil*1. Urinay tract infections *2. Tonsillitis & Pharyngitis *3. Skin &soft tissue infections *4. Otitis media. **Contra-indications of Cefadroxil*1.Hypersensitivity to cephalosporins *2.Porphyria *3.Neuromuscular disorders. *
IBIDROXIL 125mg/5ml 60ml susp.CEFADROXILGLAXO SMITHKLINEAntibiotic.cephalosporin.First-generation8.6About Cefadroxil*First Generation Cephalosporin, para-hydroxy derivative of cefalexin, Oral broad-spectrum antibiotic**Mechanism of Action *Cefadroxil is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefadroxil inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefadroxil **Indications for Cefadroxil*1. Urinay tract infections *2. Tonsillitis & Pharyngitis *3. Skin &soft tissue infections *4. Otitis media. **Contra-indications of Cefadroxil*1.Hypersensitivity to cephalosporins *2.Porphyria *3.Neuromuscular disorders. *
IBIDROXIL 250 mg 8 Caps.CEFADROXILGLAXO SMITHKLINEAntibiotic.cephalosporin.First-generation7.9About Cefadroxil*First Generation Cephalosporin, para-hydroxy derivative of cefalexin, Oral broad-spectrum antibiotic**Mechanism of Action *Cefadroxil is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefadroxil inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefadroxil **Indications for Cefadroxil*1. Urinay tract infections *2. Tonsillitis & Pharyngitis *3. Skin &soft tissue infections *4. Otitis media. **Contra-indications of Cefadroxil*1.Hypersensitivity to cephalosporins *2.Porphyria *3.Neuromuscular disorders. *
IBIDROXIL 250 mg/5ml SUSP. 60mlCEFADROXILGLAXO SMITHKLINEAntibiotic.cephalosporin.First-generation17.25About Cefadroxil*First Generation Cephalosporin, para-hydroxy derivative of cefalexin, Oral broad-spectrum antibiotic**Mechanism of Action *Cefadroxil is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefadroxil inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefadroxil **Indications for Cefadroxil*1. Urinay tract infections *2. Tonsillitis & Pharyngitis *3. Skin &soft tissue infections *4. Otitis media. **Contra-indications of Cefadroxil*1.Hypersensitivity to cephalosporins *2.Porphyria *3.Neuromuscular disorders. *
IBIDROXIL 500 mg 8 Caps.CEFADROXILGLAXO SMITHKLINEAntibiotic.cephalosporin.First-generation20About Cefadroxil*First Generation Cephalosporin, para-hydroxy derivative of cefalexin, Oral broad-spectrum antibiotic**Mechanism of Action *Cefadroxil is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefadroxil inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefadroxil **Indications for Cefadroxil*1. Urinay tract infections *2. Tonsillitis & Pharyngitis *3. Skin &soft tissue infections *4. Otitis media. **Contra-indications of Cefadroxil*1.Hypersensitivity to cephalosporins *2.Porphyria *3.Neuromuscular disorders. *
IBIDROXIL 500 mg/5ml SUSP. 60mlCEFADROXILGLAXO SMITHKLINEAntibiotic.cephalosporin.First-generation20About Cefadroxil*First Generation Cephalosporin, para-hydroxy derivative of cefalexin, Oral broad-spectrum antibiotic**Mechanism of Action *Cefadroxil is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefadroxil inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefadroxil **Indications for Cefadroxil*1. Urinay tract infections *2. Tonsillitis & Pharyngitis *3. Skin &soft tissue infections *4. Otitis media. **Contra-indications of Cefadroxil*1.Hypersensitivity to cephalosporins *2.Porphyria *3.Neuromuscular disorders. *
IMIGRAN 100mg 2 tab.SUMATRIPTANGLAXO SMITHKLINEAntimigraine.Vasoconstrictor Agents.Selective Serotonin Agonist32About Sumatriptan*Selective Serotonin 5-HT1B, 1D Agonist, Antimigraine Agent.*Mechanism of Action of Sumatriptan*Sumatriptan is a selective Serotonin (5HT1D) receptor agonist. It selectively constricts the large intracranial blood vessels of the carotid circulation and reduces the blood flow and relieves the migraine. Sumatriptan is used for the acute treatment of migraine attacks and of cluster headache. *Indications for Sumatriptan*1. Acute attack of migraine treatment with or without aura*Interactions for Sumatriptan*Ergotamine containing preparations: Concomitant use should be avoided because of vasospastic reactions. *MAOIs: Concomitant use within 2 weeks of discontinuation of MAOIs is contraindicated. *Lithium: Concomitant use must be avoided.
IMIGRAN 100mg 6 tab.SUMATRIPTANGLAXO SMITHKLINEAntimigraine.Vasoconstrictor Agents.Selective Serotonin Agonist96About Sumatriptan*Selective Serotonin 5-HT1B, 1D Agonist, Antimigraine Agent.*Mechanism of Action of Sumatriptan*Sumatriptan is a selective Serotonin (5HT1D) receptor agonist. It selectively constricts the large intracranial blood vessels of the carotid circulation and reduces the blood flow and relieves the migraine. Sumatriptan is used for the acute treatment of migraine attacks and of cluster headache. *Indications for Sumatriptan*1. Acute attack of migraine treatment with or without aura*Interactions for Sumatriptan*Ergotamine containing preparations: Concomitant use should be avoided because of vasospastic reactions. *MAOIs: Concomitant use within 2 weeks of discontinuation of MAOIs is contraindicated. *Lithium: Concomitant use must be avoided.
IMIGRAN 2 amp.SUMATRIPTANGLAXO SMITHKLINEAntimigraine.Vasoconstrictor Agents.Selective Serotonin Agonist82About Sumatriptan*Selective Serotonin 5-HT1B, 1D Agonist, Antimigraine Agent.*Mechanism of Action of Sumatriptan*Sumatriptan is a selective Serotonin (5HT1D) receptor agonist. It selectively constricts the large intracranial blood vessels of the carotid circulation and reduces the blood flow and relieves the migraine. Sumatriptan is used for the acute treatment of migraine attacks and of cluster headache. *Indications for Sumatriptan*1. Acute attack of migraine treatment with or without aura*Interactions for Sumatriptan*Ergotamine containing preparations: Concomitant use should be avoided because of vasospastic reactions. *MAOIs: Concomitant use within 2 weeks of discontinuation of MAOIs is contraindicated. *Lithium: Concomitant use must be avoided.
IMIGRAN 50mg 2 F.C. Tab.SUMATRIPTANGLAXO SMITHKLINEAntimigraine.Vasoconstrictor Agents.Selective Serotonin Agonist19.2About Sumatriptan*Selective Serotonin 5-HT1B, 1D Agonist, Antimigraine Agent.*Mechanism of Action of Sumatriptan*Sumatriptan is a selective Serotonin (5HT1D) receptor agonist. It selectively constricts the large intracranial blood vessels of the carotid circulation and reduces the blood flow and relieves the migraine. Sumatriptan is used for the acute treatment of migraine attacks and of cluster headache. *Indications for Sumatriptan*1. Acute attack of migraine treatment with or without aura*Interactions for Sumatriptan*Ergotamine containing preparations: Concomitant use should be avoided because of vasospastic reactions. *MAOIs: Concomitant use within 2 weeks of discontinuation of MAOIs is contraindicated. *Lithium: Concomitant use must be avoided.
KIROLL 200mg 10f.c.tab.OFLOXACINGLAXO SMITHKLINEAntibiotic.quinolone34.5About Ofloxacin*A second generation fluoroquinolone(quinolones), Antibiotic.**Mechanism of Action of Ofloxacin*Ofloxacin is a bactericidal drug. It act by inhibiting the enzyme DNA gyrase (Topoisomerase 2) and Topoisomerase 4.DNA gyrase helps in the formation of a highly condensed three dimensional structure of the DNA by its nicking and closing activity and also by introducing negative supercoil in to the DNA double helix. Ofloxacin inhibits DNA gyrase which results in abnormal linkage between opened DNA and gyrase and negative supercoiling is also impaired. This will inhibits transcription of DNA in to RNA and subsequent protein synthesis.*Indications for Ofloxacin*1. Bronchitis *2. Pneumonia *3. Urinary tract infection *4. Bone and joint infections *5. Intra-abdominal infections *6. Gonorrhoea *7. ENT infections *8. Skin and soft tissue infections *9. Typhoid fever *10. Prostatis *11. Otitis *12. Gynaecological infections *13. Conjunctivitis *14. Keratitis *
LACIPIL 2 mg 7 tab.LACIDIPINEGLAXO SMITHKLINEAntihypertensive.selective calcium channel blocker11.5About Lacidipine*Selective calcium channel blocker, Dihydropyridine derivative, Antihypertensive.**Mechanism of Action of Lacidipine*Lacidipine is a vasoselective long acting dihydropyridine Ca channel blocker. It exerts antihypertensive action through blocking the influx of Ca ions through voltage gated L-type Ca channels to the peripheral vascular smooth muscle cells, Coronary smooth muscle cells and to the myocardial cells. Thus causes dilatation of vascular endothelium, decrease peripheral resistance, and blood pressure. It exerts some anti atherosclerotic properties by modulating the secretion of matrix degrading metalloproteinase-9 by human macrophages and thus weakens the atherosclerotic plaque. It also has antioxidant properties and it prevents platelet aggregation.**Indications for Lacidipine*1. Hypertension*Interactions for Lacidipine*Avoid grape fruit juice as it may affect metabolism. Other interactions as with calcium channel blockers.
LACIPIL 4 mg 7tab.LACIDIPINEGLAXO SMITHKLINEAntihypertensive.selective calcium channel blocker18About Lacidipine*Selective calcium channel blocker, Dihydropyridine derivative, Antihypertensive.**Mechanism of Action of Lacidipine*Lacidipine is a vasoselective long acting dihydropyridine Ca channel blocker. It exerts antihypertensive action through blocking the influx of Ca ions through voltage gated L-type Ca channels to the peripheral vascular smooth muscle cells, Coronary smooth muscle cells and to the myocardial cells. Thus causes dilatation of vascular endothelium, decrease peripheral resistance, and blood pressure. It exerts some anti atherosclerotic properties by modulating the secretion of matrix degrading metalloproteinase-9 by human macrophages and thus weakens the atherosclerotic plaque. It also has antioxidant properties and it prevents platelet aggregation.**Indications for Lacidipine*1. Hypertension*Interactions for Lacidipine*Avoid grape fruit juice as it may affect metabolism. Other interactions as with calcium channel blockers.
LAMICTAL 100mg 30 tab.LAMOTRIGINEGLAXO SMITHKLINEAnti-epileptic.Triazine87About Lamotrigine*Phenyltriazine derivative, Anticonvulsant,Mood stabilizer.**Mechanism of Action of Lamotrigine*Lamotrigine prolongs the inactivated state of voltage sensitive neuronal sodium ion channel either by increasing the efflux or decreasing the influx of sodium ion across the cell membrane and inhibits the high frequency firing of neurons. *It blocks the voltage sensitive sodium ion channel and stabilizes the presynaptic membrane. It also prevents the release of excitatory neurotransmitters such as glutamate and aspartate receptors **Interactions for Lamotrigine*Phenytoin, carbamazepine, phenobarbitone and primidone: Enhance the metabolism of lamotrigine and may increase dose requirements. *Sodium Valproate: Reduces the metabolism of lamotrigine. *There is no evidence that lamotrigine causes clinically significant induction or inhibition of hepatic oxidative drug-metabolizing enzymes.
LAMICTAL 25mg 30 tab.LAMOTRIGINEGLAXO SMITHKLINEAnti-epileptic.Triazine30About Lamotrigine*Phenyltriazine derivative, Anticonvulsant,Mood stabilizer.**Mechanism of Action of Lamotrigine*Lamotrigine prolongs the inactivated state of voltage sensitive neuronal sodium ion channel either by increasing the efflux or decreasing the influx of sodium ion across the cell membrane and inhibits the high frequency firing of neurons. *It blocks the voltage sensitive sodium ion channel and stabilizes the presynaptic membrane. It also prevents the release of excitatory neurotransmitters such as glutamate and aspartate receptors **Interactions for Lamotrigine*Phenytoin, carbamazepine, phenobarbitone and primidone: Enhance the metabolism of lamotrigine and may increase dose requirements. *Sodium Valproate: Reduces the metabolism of lamotrigine. *There is no evidence that lamotrigine causes clinically significant induction or inhibition of hepatic oxidative drug-metabolizing enzymes.
LAMICTAL 50mg 30 tab.LAMOTRIGINEGLAXO SMITHKLINEAnti-epileptic.Triazine51About Lamotrigine*Phenyltriazine derivative, Anticonvulsant,Mood stabilizer.**Mechanism of Action of Lamotrigine*Lamotrigine prolongs the inactivated state of voltage sensitive neuronal sodium ion channel either by increasing the efflux or decreasing the influx of sodium ion across the cell membrane and inhibits the high frequency firing of neurons. *It blocks the voltage sensitive sodium ion channel and stabilizes the presynaptic membrane. It also prevents the release of excitatory neurotransmitters such as glutamate and aspartate receptors **Interactions for Lamotrigine*Phenytoin, carbamazepine, phenobarbitone and primidone: Enhance the metabolism of lamotrigine and may increase dose requirements. *Sodium Valproate: Reduces the metabolism of lamotrigine. *There is no evidence that lamotrigine causes clinically significant induction or inhibition of hepatic oxidative drug-metabolizing enzymes.
LANOXIN 0.05gm/litre paediatric elixirDIGOXINEGLAXO SMITHKLINEHeart failure.Cardiotonic Agents21.6Digoxin is derived from the leaves of a digitalis plant. Digoxin helps make the heart beat stronger and with a more regular rhythm.**Important information*You should not use digoxin if you have ventricular fibrillation (a heart rhythm disorder of the ventricles, or lower chambers of the heart that allow blood to flow out of the heart).**What happens if I miss a dose?**Take the missed dose as soon as you remember. Skip the missed dose if your next dose is less than 12 hours away. Do not take extra medicine to make up the missed dose.**
LANOXIN 0.25mg 100 tab.DIGOXINEGLAXO SMITHKLINEHeart failure.Cardiotonic Agents14.4Digoxin is derived from the leaves of a digitalis plant. Digoxin helps make the heart beat stronger and with a more regular rhythm.**Important information*You should not use digoxin if you have ventricular fibrillation (a heart rhythm disorder of the ventricles, or lower chambers of the heart that allow blood to flow out of the heart).**What happens if I miss a dose?**Take the missed dose as soon as you remember. Skip the missed dose if your next dose is less than 12 hours away. Do not take extra medicine to make up the missed dose.**
LANOXIN 0.5mg/2ml 5 amp. 5 MLDIGOXINEGLAXO SMITHKLINEHeart failure.Cardiotonic Agents16.8Digoxin is derived from the leaves of a digitalis plant. Digoxin helps make the heart beat stronger and with a more regular rhythm.**Important information*You should not use digoxin if you have ventricular fibrillation (a heart rhythm disorder of the ventricles, or lower chambers of the heart that allow blood to flow out of the heart).**What happens if I miss a dose?**Take the missed dose as soon as you remember. Skip the missed dose if your next dose is less than 12 hours away. Do not take extra medicine to make up the missed dose.**
LANVIS 40 mg 25tab.THIOGUANINEGLAXO SMITHKLINE157.25
MARCOFEN 100mg infantile 5 rectal supp.IBUPROFENGLAXO SMITHKLINENSAID.Propionic acid derivatives4.5About Ibuprofen*NSAID, a propionic acid derivative, Analgesic and anti-inflammatory.**Mechanism of Action of Ibuprofen*Ibuprofen has analgesic, anti-inflammatory and antipyretic action. It acts by inhibiting Prostaglandin (PGs) synthesis and their release at the site of injury. Prostaglandins cause tenderness and amplify the action of other algesics. Ibuprofen inhibits cyclo-oxygenase enzyme and antagonizes prostaglandin actions. It also inhibits platelet aggregation and prolongs bleeding time.**Indications for Ibuprofen*1.Rheumatoid arthritis *2.Ankylosing spondylitis *3.Acute gout *4.Joint disorders e.g. inflammatory disease in joints, crystal deposition in the joints *5.Osteoarthritis *6.For the relief of fever, pain and inflammation in dental, minor surgery and orthopedic *7.Dysmenorrhoea *8.Juvenile arthritis *9.Migraine *10.Patent ductus arteriosus(IV)
MARCOFEN 100mg/5ml 120ml susp.IBUPROFENGLAXO SMITHKLINENSAID.Propionic acid derivatives5.85About Ibuprofen*NSAID, a propionic acid derivative, Analgesic and anti-inflammatory.**Mechanism of Action of Ibuprofen*Ibuprofen has analgesic, anti-inflammatory and antipyretic action. It acts by inhibiting Prostaglandin (PGs) synthesis and their release at the site of injury. Prostaglandins cause tenderness and amplify the action of other algesics. Ibuprofen inhibits cyclo-oxygenase enzyme and antagonizes prostaglandin actions. It also inhibits platelet aggregation and prolongs bleeding time.**Indications for Ibuprofen*1.Rheumatoid arthritis *2.Ankylosing spondylitis *3.Acute gout *4.Joint disorders e.g. inflammatory disease in joints, crystal deposition in the joints *5.Osteoarthritis *6.For the relief of fever, pain and inflammation in dental, minor surgery and orthopedic *7.Dysmenorrhoea *8.Juvenile arthritis *9.Migraine *10.Patent ductus arteriosus(IV)
MARCOFEN 300mg 5 PAED. supp.IBUPROFENGLAXO SMITHKLINENSAID.Propionic acid derivatives4.75About Ibuprofen*NSAID, a propionic acid derivative, Analgesic and anti-inflammatory.**Mechanism of Action of Ibuprofen*Ibuprofen has analgesic, anti-inflammatory and antipyretic action. It acts by inhibiting Prostaglandin (PGs) synthesis and their release at the site of injury. Prostaglandins cause tenderness and amplify the action of other algesics. Ibuprofen inhibits cyclo-oxygenase enzyme and antagonizes prostaglandin actions. It also inhibits platelet aggregation and prolongs bleeding time.**Indications for Ibuprofen*1.Rheumatoid arthritis *2.Ankylosing spondylitis *3.Acute gout *4.Joint disorders e.g. inflammatory disease in joints, crystal deposition in the joints *5.Osteoarthritis *6.For the relief of fever, pain and inflammation in dental, minor surgery and orthopedic *7.Dysmenorrhoea *8.Juvenile arthritis *9.Migraine *10.Patent ductus arteriosus(IV)
MARCOFEN 400 mg 20 coated tab.IBUPROFENGLAXO SMITHKLINENSAID.Propionic acid derivatives11About Ibuprofen*NSAID, a propionic acid derivative, Analgesic and anti-inflammatory.**Mechanism of Action of Ibuprofen*Ibuprofen has analgesic, anti-inflammatory and antipyretic action. It acts by inhibiting Prostaglandin (PGs) synthesis and their release at the site of injury. Prostaglandins cause tenderness and amplify the action of other algesics. Ibuprofen inhibits cyclo-oxygenase enzyme and antagonizes prostaglandin actions. It also inhibits platelet aggregation and prolongs bleeding time.**Indications for Ibuprofen*1.Rheumatoid arthritis *2.Ankylosing spondylitis *3.Acute gout *4.Joint disorders e.g. inflammatory disease in joints, crystal deposition in the joints *5.Osteoarthritis *6.For the relief of fever, pain and inflammation in dental, minor surgery and orthopedic *7.Dysmenorrhoea *8.Juvenile arthritis *9.Migraine *10.Patent ductus arteriosus(IV)
MARCOFEN 400 mg SR 10 Caps.IBUPROFENGLAXO SMITHKLINENSAID.Propionic acid derivatives5.85About Ibuprofen*NSAID, a propionic acid derivative, Analgesic and anti-inflammatory.**Mechanism of Action of Ibuprofen*Ibuprofen has analgesic, anti-inflammatory and antipyretic action. It acts by inhibiting Prostaglandin (PGs) synthesis and their release at the site of injury. Prostaglandins cause tenderness and amplify the action of other algesics. Ibuprofen inhibits cyclo-oxygenase enzyme and antagonizes prostaglandin actions. It also inhibits platelet aggregation and prolongs bleeding time.**Indications for Ibuprofen*1.Rheumatoid arthritis *2.Ankylosing spondylitis *3.Acute gout *4.Joint disorders e.g. inflammatory disease in joints, crystal deposition in the joints *5.Osteoarthritis *6.For the relief of fever, pain and inflammation in dental, minor surgery and orthopedic *7.Dysmenorrhoea *8.Juvenile arthritis *9.Migraine *10.Patent ductus arteriosus(IV)
MARCOFEN 500mg 5 supp.IBUPROFENGLAXO SMITHKLINENSAID.Propionic acid derivatives6About Ibuprofen*NSAID, a propionic acid derivative, Analgesic and anti-inflammatory.**Mechanism of Action of Ibuprofen*Ibuprofen has analgesic, anti-inflammatory and antipyretic action. It acts by inhibiting Prostaglandin (PGs) synthesis and their release at the site of injury. Prostaglandins cause tenderness and amplify the action of other algesics. Ibuprofen inhibits cyclo-oxygenase enzyme and antagonizes prostaglandin actions. It also inhibits platelet aggregation and prolongs bleeding time.**Indications for Ibuprofen*1.Rheumatoid arthritis *2.Ankylosing spondylitis *3.Acute gout *4.Joint disorders e.g. inflammatory disease in joints, crystal deposition in the joints *5.Osteoarthritis *6.For the relief of fever, pain and inflammation in dental, minor surgery and orthopedic *7.Dysmenorrhoea *8.Juvenile arthritis *9.Migraine *10.Patent ductus arteriosus(IV)
MARCOFEN FLU 10f.c.tab.IBUPROFEN -- PSEUDOEPHEDRINEGLAXO SMITHKLINE4About Ibuprofen*NSAID, a propionic acid derivative, Analgesic and anti-inflammatory.*Mechanism of Action of Ibuprofen*Ibuprofen has analgesic, anti-inflammatory and antipyretic action. It acts by inhibiting Prostaglandin (PGs) synthesis and their release at the site of injury. Prostaglandins cause tenderness and amplify the action of other algesics. Ibuprofen inhibits cyclo-oxygenase enzyme and antagonizes prostaglandin actions. It also inhibits platelet aggregation and prolongs bleeding time.*About Pseudoephedrine*Alpha/Beta Adrenergic Agonist, a phenethylamine derivative, A nasal decongestant.*Mechanism of Action of Pseudoephedrine*It is a nasal decongestant with alpha-2 agonistic action. It produces local vasoconstriction, reduces blood flow, and causes shrinkage of mucosa which provides relief of nasal congestion. It reduces oedema of the nasal mucosa, thus improving ventilation, drainage and nasal stuffiness.
MAREVAN 1 mg 100tab.WARFARINGLAXO SMITHKLINEAnticoagulant.clotting factors activation inhibitors7About Warfarin*Synthetic coumarin derivative , Vitamin K Antagonist, Anticoagulant.*Mechanism of Action of Warfarin*It exerts it`s pharmacological action by inhibiting regeneration of active hydroquinone from vitamin K and also behaves as a competitive antagonist of vitamin K. Thus the drug interacts with synthesis of vitamin K derived clotting factors (factors- II, VII, IX, and X.) in a dose dependent manner and reduce their plasma levels. Vitamin K-hydroquinone is required for final step of gama-carboxylation of descarboxy forms of these factors. This carboxylation is essential for the ability of the clotting factors to bind Ca2 -- and to get bound to phospholipid surfaces and ultimately involve in coagulation cascade.*Indications for Warfarin*1. Thromboembolism, *2. Pulmonary embolism *3. Transient ischemic attack *4. Atrial fibrillation *5. Rheumatic heart disease *6. Deep vein thrombosis
MAREVAN 3 mg 100 tab.WARFARINGLAXO SMITHKLINEAnticoagulant.clotting factors activation inhibitors12About Warfarin*Synthetic coumarin derivative , Vitamin K Antagonist, Anticoagulant.*Mechanism of Action of Warfarin*It exerts it`s pharmacological action by inhibiting regeneration of active hydroquinone from vitamin K and also behaves as a competitive antagonist of vitamin K. Thus the drug interacts with synthesis of vitamin K derived clotting factors (factors- II, VII, IX, and X.) in a dose dependent manner and reduce their plasma levels. Vitamin K-hydroquinone is required for final step of gama-carboxylation of descarboxy forms of these factors. This carboxylation is essential for the ability of the clotting factors to bind Ca2 -- and to get bound to phospholipid surfaces and ultimately involve in coagulation cascade.*Indications for Warfarin*1. Thromboembolism, *2. Pulmonary embolism *3. Transient ischemic attack *4. Atrial fibrillation *5. Rheumatic heart disease *6. Deep vein thrombosis
MAREVAN 5 mg 100 tab.WARFARINGLAXO SMITHKLINEAnticoagulant.clotting factors activation inhibitors16.8About Warfarin*Synthetic coumarin derivative , Vitamin K Antagonist, Anticoagulant.*Mechanism of Action of Warfarin*It exerts it`s pharmacological action by inhibiting regeneration of active hydroquinone from vitamin K and also behaves as a competitive antagonist of vitamin K. Thus the drug interacts with synthesis of vitamin K derived clotting factors (factors- II, VII, IX, and X.) in a dose dependent manner and reduce their plasma levels. Vitamin K-hydroquinone is required for final step of gama-carboxylation of descarboxy forms of these factors. This carboxylation is essential for the ability of the clotting factors to bind Ca2 -- and to get bound to phospholipid surfaces and ultimately involve in coagulation cascade.*Indications for Warfarin*1. Thromboembolism, *2. Pulmonary embolism *3. Transient ischemic attack *4. Atrial fibrillation *5. Rheumatic heart disease *6. Deep vein thrombosis
MOTINORM 10mg 30 TABS.DOMPERIDONEGLAXO SMITHKLINE28.25About Domperidone*Antidopaminergic, Motility stimulant,Piperidine derivative, Antiemetic, anti-vertigo.*Mechanism of Action of Domperidone*Domperidone is a potent dopamine receptor antagonist. It acts centrally and blocks the Dopamine receptor in the Chemoreceptor trigger zone and produces Antiemetic effect. *Domperidone acts peripherally in the gastrointestinal system and increases oesophageal peristalsis, oesophageal sphincter pressure and gastric motility. These all facilitates gastric emptying. Domperidone is used in migraine to relieve nausea and vomiting. *Anaesthetic adjuncts: It is used preoperatively in order to reduce the post operative vomiting. **Indications for Domperidone*1.Nausea and vomiting associated with gastrointestinal disorder and migraine. *2.Delayed gastric emptying of functional origin *3.As an Antiemetic in patient receiving cytotoxic drugs *4.Preanaesthetic medication
MOTINORM 10mg infant supp. (CANCELLED)DOMPERIDONEGLAXO SMITHKLINE4.5About Domperidone*Antidopaminergic, Motility stimulant,Piperidine derivative, Antiemetic, anti-vertigo.*Mechanism of Action of Domperidone*Domperidone is a potent dopamine receptor antagonist. It acts centrally and blocks the Dopamine receptor in the Chemoreceptor trigger zone and produces Antiemetic effect. *Domperidone acts peripherally in the gastrointestinal system and increases oesophageal peristalsis, oesophageal sphincter pressure and gastric motility. These all facilitates gastric emptying. Domperidone is used in migraine to relieve nausea and vomiting. *Anaesthetic adjuncts: It is used preoperatively in order to reduce the post operative vomiting. **Indications for Domperidone*1.Nausea and vomiting associated with gastrointestinal disorder and migraine. *2.Delayed gastric emptying of functional origin *3.As an Antiemetic in patient receiving cytotoxic drugs *4.Preanaesthetic medication
MOTINORM 30mg 5 supp.DOMPERIDONEGLAXO SMITHKLINE7.75About Domperidone*Antidopaminergic, Motility stimulant,Piperidine derivative, Antiemetic, anti-vertigo.*Mechanism of Action of Domperidone*Domperidone is a potent dopamine receptor antagonist. It acts centrally and blocks the Dopamine receptor in the Chemoreceptor trigger zone and produces Antiemetic effect. *Domperidone acts peripherally in the gastrointestinal system and increases oesophageal peristalsis, oesophageal sphincter pressure and gastric motility. These all facilitates gastric emptying. Domperidone is used in migraine to relieve nausea and vomiting. *Anaesthetic adjuncts: It is used preoperatively in order to reduce the post operative vomiting. **Indications for Domperidone*1.Nausea and vomiting associated with gastrointestinal disorder and migraine. *2.Delayed gastric emptying of functional origin *3.As an Antiemetic in patient receiving cytotoxic drugs *4.Preanaesthetic medication
MOTINORM 5 MG/5ML SUSP. 125 MLDOMPERIDONEGLAXO SMITHKLINE12About Domperidone*Antidopaminergic, Motility stimulant,Piperidine derivative, Antiemetic, anti-vertigo.*Mechanism of Action of Domperidone*Domperidone is a potent dopamine receptor antagonist. It acts centrally and blocks the Dopamine receptor in the Chemoreceptor trigger zone and produces Antiemetic effect. *Domperidone acts peripherally in the gastrointestinal system and increases oesophageal peristalsis, oesophageal sphincter pressure and gastric motility. These all facilitates gastric emptying. Domperidone is used in migraine to relieve nausea and vomiting. *Anaesthetic adjuncts: It is used preoperatively in order to reduce the post operative vomiting. **Indications for Domperidone*1.Nausea and vomiting associated with gastrointestinal disorder and migraine. *2.Delayed gastric emptying of functional origin *3.As an Antiemetic in patient receiving cytotoxic drugs *4.Preanaesthetic medication
MOTINORM 60mg supp. (CANCELLED)DOMPERIDONEGLAXO SMITHKLINE11About Domperidone*Antidopaminergic, Motility stimulant,Piperidine derivative, Antiemetic, anti-vertigo.*Mechanism of Action of Domperidone*Domperidone is a potent dopamine receptor antagonist. It acts centrally and blocks the Dopamine receptor in the Chemoreceptor trigger zone and produces Antiemetic effect. *Domperidone acts peripherally in the gastrointestinal system and increases oesophageal peristalsis, oesophageal sphincter pressure and gastric motility. These all facilitates gastric emptying. Domperidone is used in migraine to relieve nausea and vomiting. *Anaesthetic adjuncts: It is used preoperatively in order to reduce the post operative vomiting. **Indications for Domperidone*1.Nausea and vomiting associated with gastrointestinal disorder and migraine. *2.Delayed gastric emptying of functional origin *3.As an Antiemetic in patient receiving cytotoxic drugs *4.Preanaesthetic medication
MYOLGIN 250/300 MG 20 Caps.CHLORZOXAZONE -- PARACETAMOL(ACETAMINOPHEN)GLAXO SMITHKLINE16"(Indications) : *This medication is a muscle relaxant, prescribed for muscle spasm and the resulting pain or discomfort. It is used in combination with physical therapy, analgesics (such as aspirin or acetaminophen), and rest. *About Chlorzoxazone*A benzoxazolone derivative, Centrally acting Muscle relaxant and mild sedative.*Mechanism of Action of Chlorzoxazone*This muscle relaxant works by blocking nerve impulses (or pain sensations) that are sent to your brain. It inhibits degranulation of mast cells, subsequently preventing the release of histamine and slow-reacting substance of anaphylaxis (SRS-A), mediators of type I allergic reactions. It may also reduce the release of inflammatory leukotrienes. Chlorzoxazone may act by inhibiting calcium influx. *"
NIMBEX 2mg/ml (10ml=20mg) 5amps.CISATRACURIUM BESYLATEGLAXO SMITHKLINEAnesthetic.Muscle Relaxant.Non depolarizing250"Description *Cisatracurium Besylate is a nondepolarizing skeletal muscle relaxant for intravenous administration.**Indication *For inpatients and outpatients as an adjunct to general anesthesia, to facilitate tracheal intubation, and to provide skeletal muscle relaxation during surgery or mechanical ventilation in the ICU.**Mechanism of action *Cisatracurium Besylate binds to the nicotinic acetycholine (cholinergic) receptors in the motor endplate and blocks access to the receptors. In the process of binding, the receptor is actually activated - causing a process known as depolarization. Since it is not degraded in the neuromuscular junction, the depolarized membrane remains depolarized and unresponsive to any other impulse, causing muscle paralysis."
NIMBEX 2mg/ml (2.5ml=5mg) 5 amps.CISATRACURIUM BESYLATEGLAXO SMITHKLINEAnesthetic.Muscle Relaxant.Non depolarizing81"Description *Cisatracurium Besylate is a nondepolarizing skeletal muscle relaxant for intravenous administration.**Indication *For inpatients and outpatients as an adjunct to general anesthesia, to facilitate tracheal intubation, and to provide skeletal muscle relaxation during surgery or mechanical ventilation in the ICU.**Mechanism of action *Cisatracurium Besylate binds to the nicotinic acetycholine (cholinergic) receptors in the motor endplate and blocks access to the receptors. In the process of binding, the receptor is actually activated - causing a process known as depolarization. Since it is not degraded in the neuromuscular junction, the depolarized membrane remains depolarized and unresponsive to any other impulse, causing muscle paralysis."
NIMBEX 2mg/ml (5ml=10mg) 5 amps.CISATRACURIUM BESYLATEGLAXO SMITHKLINEAnesthetic.Muscle Relaxant.Non depolarizing146"Description *Cisatracurium Besylate is a nondepolarizing skeletal muscle relaxant for intravenous administration.**Indication *For inpatients and outpatients as an adjunct to general anesthesia, to facilitate tracheal intubation, and to provide skeletal muscle relaxation during surgery or mechanical ventilation in the ICU.**Mechanism of action *Cisatracurium Besylate binds to the nicotinic acetycholine (cholinergic) receptors in the motor endplate and blocks access to the receptors. In the process of binding, the receptor is actually activated - causing a process known as depolarization. Since it is not degraded in the neuromuscular junction, the depolarized membrane remains depolarized and unresponsive to any other impulse, causing muscle paralysis."
NOVIRUS 200 mg 8 Hard gelatin Caps.ACYCLOVIRGLAXO SMITHKLINEAnti-Viral.Nucleoside13.2(Indications) : *This medication is an antiviral agent, prescribed for herpes simplex, genital herpes, herpes zoster and chickenpox. It slows down the growth and spread of the herpes virus. Acyclovir is also sometimes used to treat eczema herpeticum, herpes infections of the skin, eyes, nose, and mouth in patients with human immunodeficiency virus (HIV) . ** (Dosage) : *Acute Treatment of Herpes Zoster: 800 mg every 4 hours orally, 5 times daily for 7 to 10 days. *Genital Herpes: Treatment of Initial Genital Herpes: 200 mg every 4 hours, 5 times daily for 10 days. *Chronic Suppressive Therapy for Recurrent Disease: 400 mg 2 times daily for up to 12 months, followed by re-evaluation. *Treatment of Chickenpox: Children (2 years of age and older): 20 mg/kg per dose orally 4 times daily (80 mg/kg/day) for 5 days. *Adults and Children over 40 kg: 800 mg 4 times daily for 5 days. **
OXYBRAL 30mg 20 S.R.caps.VINCAMINEGLAXO SMITHKLINE18
PRIMALEVE 28 CAPSULESEVENING PRIMROSE OIL -- DL-ALPHA TOCOPHEROLGLAXO SMITHKLINE30Improve body functions
PYREMOL 300mg supp.PARACETAMOL(ACETAMINOPHEN)GLAXO SMITHKLINEAntipyretic3.15About Paracetamol*Acetanilide derivative, Non narcotic Analgesic,Antipyretic.*Mechanism of Action of Paracetamol*Paracetamol has analgesic and antipyretic action. *It is more active on cyclo-oxygenase enzyme in brain. Peripherally it is a poor inhibitor of prostaglandin synthesis. *Analgesic action: Paracetamol raises the pain threshold and produces analgesic effect. *Antipyretic action: Paracetamol lowers fever by direct action on the thermoregulatory centre in the Hypothalamus and block the effects of endogenous pyrogen. *Indications for Paracetamol*1. To relieve pain and fever *2. Acute gout *3. Migraine *Interactions for Paracetamol*Cholestyramine: Reduces absorption of paracetamol. *Charcoal: Activated, administered immediately reduces absorption of paracetamol. *Domperidone and metochlopramide: Enhance absorption of paracetamol. *Alcohol: Chronic excessive ingestion of alcohol potentiates hepatotoxicity of paracetamol. *
RAPIFLAM 12.5mg 5 SUPP.DICLOFENAC POTASSIUMGLAXO SMITHKLINENSAID.Acetic acid derivatives1.5About Diclofenac Potassium*NSAID, anti-inflammatory ,antipyretic and analgesic.**Mechanism of Action of Diclofenac Potassium*Diclofenac possess analgesic, anti-inflammatory and antipyretic action. It inhibits the enzyme cyclo-oxygenase and there by inhibits the synthesis of Prostaglandins (((PGs))). It is more potent against cyclo-oxygenase-2 enzyme as compared to other NSAIDs like Indomethacin, Naproxen etc. It reduces intracellular concentrations of free arachidonic acid in leukocyte by altering its release or uptake.**Indications for Diclofenac Potassium*1.Rheumatoid arthritis *2.Ankylosing spondylitis *3.Acute gout *4.Joint disorders e.g. inflammatory disease in joints, crystal deposition in the joints *5.Osteoarthritis *6.For the relief of pain and inflammation in dental minor surgery and orthopedic *7.Dysmenorrhoea
RAPIFLAM 25mg 10 enteric coated tab.DICLOFENAC POTASSIUMGLAXO SMITHKLINENSAID.Acetic acid derivatives6About Diclofenac Potassium*NSAID, anti-inflammatory ,antipyretic and analgesic.**Mechanism of Action of Diclofenac Potassium*Diclofenac possess analgesic, anti-inflammatory and antipyretic action. It inhibits the enzyme cyclo-oxygenase and there by inhibits the synthesis of Prostaglandins (((PGs))). It is more potent against cyclo-oxygenase-2 enzyme as compared to other NSAIDs like Indomethacin, Naproxen etc. It reduces intracellular concentrations of free arachidonic acid in leukocyte by altering its release or uptake.**Indications for Diclofenac Potassium*1.Rheumatoid arthritis *2.Ankylosing spondylitis *3.Acute gout *4.Joint disorders e.g. inflammatory disease in joints, crystal deposition in the joints *5.Osteoarthritis *6.For the relief of pain and inflammation in dental minor surgery and orthopedic *7.Dysmenorrhoea
RAPIFLAM 25mg 5 SUPP.DICLOFENAC POTASSIUMGLAXO SMITHKLINENSAID.Acetic acid derivatives1.65About Diclofenac Potassium*NSAID, anti-inflammatory ,antipyretic and analgesic.**Mechanism of Action of Diclofenac Potassium*Diclofenac possess analgesic, anti-inflammatory and antipyretic action. It inhibits the enzyme cyclo-oxygenase and there by inhibits the synthesis of Prostaglandins (((PGs))). It is more potent against cyclo-oxygenase-2 enzyme as compared to other NSAIDs like Indomethacin, Naproxen etc. It reduces intracellular concentrations of free arachidonic acid in leukocyte by altering its release or uptake.**Indications for Diclofenac Potassium*1.Rheumatoid arthritis *2.Ankylosing spondylitis *3.Acute gout *4.Joint disorders e.g. inflammatory disease in joints, crystal deposition in the joints *5.Osteoarthritis *6.For the relief of pain and inflammation in dental minor surgery and orthopedic *7.Dysmenorrhoea
RAPIFLAM 50mg 10 enteric coated tab.DICLOFENAC POTASSIUMGLAXO SMITHKLINENSAID.Acetic acid derivatives8About Diclofenac Potassium*NSAID, anti-inflammatory ,antipyretic and analgesic.**Mechanism of Action of Diclofenac Potassium*Diclofenac possess analgesic, anti-inflammatory and antipyretic action. It inhibits the enzyme cyclo-oxygenase and there by inhibits the synthesis of Prostaglandins (((PGs))). It is more potent against cyclo-oxygenase-2 enzyme as compared to other NSAIDs like Indomethacin, Naproxen etc. It reduces intracellular concentrations of free arachidonic acid in leukocyte by altering its release or uptake.**Indications for Diclofenac Potassium*1.Rheumatoid arthritis *2.Ankylosing spondylitis *3.Acute gout *4.Joint disorders e.g. inflammatory disease in joints, crystal deposition in the joints *5.Osteoarthritis *6.For the relief of pain and inflammation in dental minor surgery and orthopedic *7.Dysmenorrhoea
Revolade 25mg 14 TabsEltrombopag OlamineGLAXO SMITHKLINE1600It is a medication that has been developed for conditions that lead to thrombocytopenia (abnormally low platelet counts). It is a small molecule agonist of the c-mpl (TpoR) receptor, which is the physiological target of the hormone thrombopoietin.
Revolade 50mg 14 TabsEltrombopag OlamineGLAXO SMITHKLINE3200It is a medication that has been developed for conditions that lead to thrombocytopenia (abnormally low platelet counts). It is a small molecule agonist of the c-mpl (TpoR) receptor, which is the physiological target of the hormone thrombopoietin.
RHEUMAFEN 100mg S.R.caps.DICLOFENAC SODIUMGLAXO SMITHKLINENSAID.Acetic acid derivatives12.6"Description *A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt. **Indication :*For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.**Mechanism of action The antiinflammatory effects of diclofenac are believed to be due to inhibition of both leukocyte migration and the enzyme cylooxygenase (COX-1 and COX-2), leading to the peripheral inhibition of prostaglandin synthesis. As prostaglandins sensitize pain receptors, inhibition of their synthesis is responsible for the analgesic effects of diclofenac. Antipyretic effects may be due to action on the hypothalamus, resulting in peripheral dilation, increased cutaneous blood flow, and subsequent heat dissipation."
RHEUMAFEN 25mg 20 enteric coated tab.DICLOFENAC SODIUMGLAXO SMITHKLINENSAID.Acetic acid derivatives8.85"Description *A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt. **Indication :*For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.**Mechanism of action The antiinflammatory effects of diclofenac are believed to be due to inhibition of both leukocyte migration and the enzyme cylooxygenase (COX-1 and COX-2), leading to the peripheral inhibition of prostaglandin synthesis. As prostaglandins sensitize pain receptors, inhibition of their synthesis is responsible for the analgesic effects of diclofenac. Antipyretic effects may be due to action on the hypothalamus, resulting in peripheral dilation, increased cutaneous blood flow, and subsequent heat dissipation."
RHEUMAFEN 50mg 20 enteric coated tab.DICLOFENAC SODIUMGLAXO SMITHKLINENSAID.Acetic acid derivatives10.3"Description *A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt. **Indication :*For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.**Mechanism of action The antiinflammatory effects of diclofenac are believed to be due to inhibition of both leukocyte migration and the enzyme cylooxygenase (COX-1 and COX-2), leading to the peripheral inhibition of prostaglandin synthesis. As prostaglandins sensitize pain receptors, inhibition of their synthesis is responsible for the analgesic effects of diclofenac. Antipyretic effects may be due to action on the hypothalamus, resulting in peripheral dilation, increased cutaneous blood flow, and subsequent heat dissipation."
RHEUMAFEN 75 mg SR 10 Caps.DICLOFENAC SODIUMGLAXO SMITHKLINENSAID.Acetic acid derivatives10.6"Description *A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt. **Indication :*For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.**Mechanism of action The antiinflammatory effects of diclofenac are believed to be due to inhibition of both leukocyte migration and the enzyme cylooxygenase (COX-1 and COX-2), leading to the peripheral inhibition of prostaglandin synthesis. As prostaglandins sensitize pain receptors, inhibition of their synthesis is responsible for the analgesic effects of diclofenac. Antipyretic effects may be due to action on the hypothalamus, resulting in peripheral dilation, increased cutaneous blood flow, and subsequent heat dissipation."
RHEUMAFEN ACTI-GEL 1% gel 15 GMDICLOFENAC SODIUMGLAXO SMITHKLINENSAID.Acetic acid derivatives5"Description *A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt. **Indication :*For the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.**Mechanism of action The antiinflammatory effects of diclofenac are believed to be due to inhibition of both leukocyte migration and the enzyme cylooxygenase (COX-1 and COX-2), leading to the peripheral inhibition of prostaglandin synthesis. As prostaglandins sensitize pain receptors, inhibition of their synthesis is responsible for the analgesic effects of diclofenac. Antipyretic effects may be due to action on the hypothalamus, resulting in peripheral dilation, increased cutaneous blood flow, and subsequent heat dissipation."
RHEUMAFEN FORTE supp.DICLOFENAC SODIUM -- DIFLUNISALGLAXO SMITHKLINENSAID.Analgesic.Combination7About Diflunisal*NSAID,salicylic acid derivative, Nonopioid analgesic, anti-inflammatory.*Diclofenac Sodium*Mechanism of Action of Diclofenac Sodium*Diclofenac possess analgesic, anti-inflammatory and antipyretic action. It inhibits the enzyme cyclo-oxygenase and there by inhibits the synthesis of Prostaglandins (PGs). It is more potent against cyclo-oxygenase-2 enzyme as compared to other NSAIDs like Indomethacin, Naproxen etc. It reduces intracellular concentrations of free arachidonic acid in leukocyte by altering its release or uptake. .*Interactions for Diclofenac Sodium*Lithium & Digoxin : Blood levels of lithium and digoxin increased leading to enhanced efficacy and posible toxicity. *Diuretics : Inhibits diuretics but efficacy of potassium sparing diuretics enhanced. *Methotrexate : Toxicity enhanced. *Salicylates : Efficacy of salicylates reduced. *Cyclosporine : Increases nephrotoxicity of both agents. *Hydantoins : Increases serum levels resulting in toxicity.
SEMPREX 8mg 24 hard gelatin Caps.ACRIVASTINEGLAXO SMITHKLINEAnti-histamine.Second-Generation18.8"Description:*a non-sedating antihistamine**Indication :*Relieving the symptoms of nasal allergies (allergic rhinitis) such as hay fever.*Relieving the symptoms of an itchy skin rash with no known cause (chronic idiopathic urticaria).**Mechanism of action :*Acrivastine works by blocking histamine H1 receptors. It doesn t prevent the actual release of histamine from mast cells, but prevents it binding to its receptors. This in turn prevents the release of other allergy chemicals and increased blood supply to the area, and provides relief from the typical symptoms of nasal allergies such as hayfever.*Acrivastine can also be used to relieve the symptoms of various itchy rashes and hives. Blocking the actions of histamine relieves the itching and reduces the rash**dosage:*Adults and adolescents aged 12 years and over should take one capsule up to three times a day when needed to relieve symptoms.**"
SEPTRIN D.S 10 coated tab.SULPHAMETHOXAZOLE -- TRIMETHOPRIMGLAXO SMITHKLINE9"Indication For the treatment bacterial infections causing bronchitis, prostatitis and urinary tract infections.*Mechanism of action Sulfonamides inhibit the enzymatic conversion of pteridine and p-aminobenzoic acid (PABA) to dihydropteroic acid by competing with PABA for binding to dihydrofolate synthetase, an intermediate of tetrahydrofolic acid (THF) synthesis. THF is required for the synthesis of purines and dTMP and inhibition of its synthesis inhibits bacterial growth. Pyrimethamine and trimethoprim inhibit dihydrofolate reductase, another step in THF synthesis, and therefore act synergistically with the sulfonamides."
SEPTRIN paediatric 200/40 120ml susp.SULPHAMETHOXAZOLE -- TRIMETHOPRIMGLAXO SMITHKLINE8"Indication For the treatment bacterial infections causing bronchitis, prostatitis and urinary tract infections.*Mechanism of action Sulfonamides inhibit the enzymatic conversion of pteridine and p-aminobenzoic acid (PABA) to dihydropteroic acid by competing with PABA for binding to dihydrofolate synthetase, an intermediate of tetrahydrofolic acid (THF) synthesis. THF is required for the synthesis of purines and dTMP and inhibition of its synthesis inhibits bacterial growth. Pyrimethamine and trimethoprim inhibit dihydrofolate reductase, another step in THF synthesis, and therefore act synergistically with the sulfonamides."
SEREVENT 25mcg rotadisksSALMETEROLGLAXO SMITHKLINE60About Salmeterol*A long-acting beta2-adrenergic agonist, Phenethylamine derivative, Bronchodilator(Antiasthma).*Mechanism of Action of Salmeterol*Salmeterol is a long acting ?2 receptor agonist. It directly relaxes the airway smooth muscles and produces bronchodilation. Stimulation of ?2 receptors activates Gs adenylyl-cyclase -cyclic AMP path way and produces reduction in smooth muscle tone. ?2 receptor agonists also increases the conductance of large Ca2 -- sensitive K -- channels in airway smooth muscles and leads to membrane hyperpolarisation and relaxation of smooth muscles. Its ?2 receptor selectivity is about 50 times greater than Salbutamol. *?2 receptor agonists also suppress the release of Leukotrienes and histamine from the mast cells in the lung tissue and enhance mucociliary function and decrease micro vascular permeability and also inhibits Phospholipase A2 which produces inhibition of prostaglandins production.
SEROXAT 20mg 30 F.C.Tab.PAROXETINEGLAXO SMITHKLINEpsychiatric.Antidepressants74.25About Paroxetine*A selective serotonin reuptake inhibitor (SSRI), Anti-depressant.*Mechanism of Action of Paroxetine*Paroxetine blocks the re-uptake of neurotransmitter Serotonin from the synapse in to the presynaptic nerve terminal in the CNS. This will prolong the action of Serotonin (5HT) and it is useful in the treatment of depression. *Indications for Paroxetine*1. Depression *2. Obsessive compulsive disorder *3. Panic disorder *4. Social anxiety disorder *Interactions for Paroxetine*Monoamine oxidase inhibitors: Avoid concomitant use since serious, sometimes fatal reactions have been reported. Paroxetine hydrochloride should not be used in combination with a MAOI, or within 14 days of discontinuing treatment with MAOI. *Warfarin: Concomitant administration should be undertaken with caution. *Drugs affecting hepatic metabolism: The metabolism and pharmacokinetics of paroxetine may be affected by the induction or inhibition of drug metabolizing enzymes. *
SEROXAT CR 12.5mg enteric 10f.c.tabPAROXETINEGLAXO SMITHKLINEpsychiatric.Antidepressants30About Paroxetine*A selective serotonin reuptake inhibitor (SSRI), Anti-depressant.*Mechanism of Action of Paroxetine*Paroxetine blocks the re-uptake of neurotransmitter Serotonin from the synapse in to the presynaptic nerve terminal in the CNS. This will prolong the action of Serotonin (5HT) and it is useful in the treatment of depression. *Indications for Paroxetine*1. Depression *2. Obsessive compulsive disorder *3. Panic disorder *4. Social anxiety disorder *Interactions for Paroxetine*Monoamine oxidase inhibitors: Avoid concomitant use since serious, sometimes fatal reactions have been reported. Paroxetine hydrochloride should not be used in combination with a MAOI, or within 14 days of discontinuing treatment with MAOI. *Warfarin: Concomitant administration should be undertaken with caution. *Drugs affecting hepatic metabolism: The metabolism and pharmacokinetics of paroxetine may be affected by the induction or inhibition of drug metabolizing enzymes. *
SEROXAT CR 25mg enteric 10f.c.tabPAROXETINEGLAXO SMITHKLINEpsychiatric.Antidepressants40About Paroxetine*A selective serotonin reuptake inhibitor (SSRI), Anti-depressant.*Mechanism of Action of Paroxetine*Paroxetine blocks the re-uptake of neurotransmitter Serotonin from the synapse in to the presynaptic nerve terminal in the CNS. This will prolong the action of Serotonin (5HT) and it is useful in the treatment of depression. *Indications for Paroxetine*1. Depression *2. Obsessive compulsive disorder *3. Panic disorder *4. Social anxiety disorder *Interactions for Paroxetine*Monoamine oxidase inhibitors: Avoid concomitant use since serious, sometimes fatal reactions have been reported. Paroxetine hydrochloride should not be used in combination with a MAOI, or within 14 days of discontinuing treatment with MAOI. *Warfarin: Concomitant administration should be undertaken with caution. *Drugs affecting hepatic metabolism: The metabolism and pharmacokinetics of paroxetine may be affected by the induction or inhibition of drug metabolizing enzymes. *
SUPRAVIT 28 Caps.MINERALS -- VITAMINSGLAXO SMITHKLINEMulti-Vitamins.Comination18About Minerals*Dietary mineral supplement, Nutritional supplement.*
THEO 100mg S.R.caps.THEOPHYLLINEGLAXO SMITHKLINEBronchodilator.Phosphodiesterase Inhibitors4.75About Theophylline*Bronchodilator, a methylxanthine derivative, Anti asthma, in COPD.*Mechanism of Action of Theophylline*It inhibit phosphodiesterase enzyme which degrades cyclic nucleotides intracellularly and it results the cyclic AMP accumulation in the cell. This cause bronchodialatation, cardiac stimulation and vasodilatation. This drug release calcium from sarcoplasmic reticulam, especially in cardiac muscles and results increased cardiac muscle contraction. This drug also blocks adenosine receptors (adenosine acts as a local mediator in CNS & CVS and other organs- which contracts smooth muscles, especially in bronchi, blood vessels etc). This results bronchodialatation and vasodialatation.*Indications for Theophylline*1. Asthma *2. Chronic obstructive pulmonary disease *3. Chronic bronchitis *4. Emphysema *5. It can be used in premature infants who stop breathing *
THEO 200mg S.R. 20 caps.THEOPHYLLINEGLAXO SMITHKLINEBronchodilator.Phosphodiesterase Inhibitors9.2About Theophylline*Bronchodilator, a methylxanthine derivative, Anti asthma, in COPD.*Mechanism of Action of Theophylline*It inhibit phosphodiesterase enzyme which degrades cyclic nucleotides intracellularly and it results the cyclic AMP accumulation in the cell. This cause bronchodialatation, cardiac stimulation and vasodilatation. This drug release calcium from sarcoplasmic reticulam, especially in cardiac muscles and results increased cardiac muscle contraction. This drug also blocks adenosine receptors (adenosine acts as a local mediator in CNS & CVS and other organs- which contracts smooth muscles, especially in bronchi, blood vessels etc). This results bronchodialatation and vasodialatation.*Indications for Theophylline*1. Asthma *2. Chronic obstructive pulmonary disease *3. Chronic bronchitis *4. Emphysema *5. It can be used in premature infants who stop breathing *
THEO 300mg S.R.caps.THEOPHYLLINEGLAXO SMITHKLINEBronchodilator.Phosphodiesterase Inhibitors5.1About Theophylline*Bronchodilator, a methylxanthine derivative, Anti asthma, in COPD.*Mechanism of Action of Theophylline*It inhibit phosphodiesterase enzyme which degrades cyclic nucleotides intracellularly and it results the cyclic AMP accumulation in the cell. This cause bronchodialatation, cardiac stimulation and vasodilatation. This drug release calcium from sarcoplasmic reticulam, especially in cardiac muscles and results increased cardiac muscle contraction. This drug also blocks adenosine receptors (adenosine acts as a local mediator in CNS & CVS and other organs- which contracts smooth muscles, especially in bronchi, blood vessels etc). This results bronchodialatation and vasodialatation.*Indications for Theophylline*1. Asthma *2. Chronic obstructive pulmonary disease *3. Chronic bronchitis *4. Emphysema *5. It can be used in premature infants who stop breathing *
TRACRIUM 25mg/2.5ml ampouleATRACURIUM BESYLATEGLAXO SMITHKLINE90.85"Indication For use, as an adjunct to general anesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.*Pharmacodynamics Atracurium is a nondepolarizing skeletal muscle relaxant. Atracurium can be used most advantageously if muscle twitch response to peripheral nerve stimulation is monitored to assess degree of muscle relaxation. The duration of neuromuscular block produced by Atracurium is approximately one third to one half the duration of block by d-tubocurarine, metocurine, and pancuronium at initially equipotent doses. As with other nondepolarizing neuromuscular blockers, the time to onset of paralysis decreases and the duration of maximum effect increases with increasing doses of Atracurium. Repeated administration of maintenance doses of Atracurium has no cumulative effect on the duration of neuromuscular block if recovery is allowed to begin prior to repeat dosing."
TRISOLVIN 10 soft gelatin Caps.AMBROXOL -- GUAIFENESIN -- THEOPHYLLINEGLAXO SMITHKLINE5.2"(Indications) : *This medication is a mucolytic agent, prescribed for various respiratory diseases such as emphysema with bronchitis pneumoconiosis, chronic inflammatory pulmonary conditions, tracheobronchitis (respiratory tract inflammation), bronchiectasis, bronchitis with bronchospasm asthma. *Theophylline and guaifenesin combination is used to treat or prevent the symptoms of asthma or to treat chronic bronchitis and emphysema. This medicine relieves cough, wheezing, shortness of breath, and troubled breathing. It works by opening up the bronchial tubes (air passages) of the lungs and increasing the flow of air through them. ***"
TYKERB 250mg 70 F.C. Tab.LAPATINIBGLAXO SMITHKLINE4297"Mechanism of action Lapatinib is a 4-anilinoquinazoline kinase inhibitor of the intracellular tyrosine kinase domains of both epidermal growth factor receptor (HER1/EGFR/ERBB1) and human epidermal growth factor receptor type 2 (HER2/ERBB2)with a dissociation half-life of =300 minutes. Lapatinib inhibits ERBB-driven tumor cell growth in vitro and in various animal models. An additive effect was demonstrated in an in vitro study when lapatinib and 5-florouracil (the active metabolite of capecitabine) were used in combination in the 4 tumor cell lines tested. The growth inhibitory effects of lapatinib were evaluated in trastuzumab-conditioned cell lines. Lapatinib retained significant activity against breast cancer cell lines selected for long-term growth in trastuzumab-containing medium in vitro. These in vitro findings suggest non-cross-resistance between these two agents."
ULTIVA 1mg I.V.vialREMIFENTANILGLAXO SMITHKLINE20About Remifentanil*Ultra short acting synthetic opioid analgesics*Mechanism of Action of Remifentanil*Remifentanil is a specific mu-type-opioid receptor agonist. Hence, it causes a reduction in sympathetic nervous system tone, respiratory depression and analgesia*Indications for Remifentanil*1.Analgesia during Induction of anaesthesia *2.Continuation of analgesia into immediate post operative period *Interactions for Remifentanil*Increased CNS depression with inhaled and IV anaesthetics, benzodiazepines *Increased hypotension and bradycardia with cardiac depressants (e.g. ?-blockers, calcium channel blockers) *Increased CNS depressant with sodium oxybate
ULTIVA 2mg I.V.vialREMIFENTANILGLAXO SMITHKLINE30About Remifentanil*Ultra short acting synthetic opioid analgesics*Mechanism of Action of Remifentanil*Remifentanil is a specific mu-type-opioid receptor agonist. Hence, it causes a reduction in sympathetic nervous system tone, respiratory depression and analgesia*Indications for Remifentanil*1.Analgesia during Induction of anaesthesia *2.Continuation of analgesia into immediate post operative period *Interactions for Remifentanil*Increased CNS depression with inhaled and IV anaesthetics, benzodiazepines *Increased hypotension and bradycardia with cardiac depressants (e.g. ?-blockers, calcium channel blockers) *Increased CNS depressant with sodium oxybate
ULTIVA 5mg vialREMIFENTANILGLAXO SMITHKLINE52About Remifentanil*Ultra short acting synthetic opioid analgesics*Mechanism of Action of Remifentanil*Remifentanil is a specific mu-type-opioid receptor agonist. Hence, it causes a reduction in sympathetic nervous system tone, respiratory depression and analgesia*Indications for Remifentanil*1.Analgesia during Induction of anaesthesia S2.Continuation of analgesia into immediate post operative period SInteractions for RemifentanilSIncreased CNS depression with inhaled and IV anaesthetics, benzodiazepines SIncreased hypotension and bradycardia with cardiac depressants (e.g. ?-blockers, calcium channel blockers) SIncreased CNS depressant with sodium oxybate
ULTRAFEN 1% CREAM 15 GMIBUPROFENGLAXO SMITHKLINENSAID.Propionic acid derivatives4.5About Ibuprofen*NSAID, a propionic acid derivative, Analgesic and anti-inflammatory.**Mechanism of Action of Ibuprofen*Ibuprofen has analgesic, anti-inflammatory and antipyretic action. It acts by inhibiting Prostaglandin (PGs) synthesis and their release at the site of injury. Prostaglandins cause tenderness and amplify the action of other algesics. Ibuprofen inhibits cyclo-oxygenase enzyme and antagonizes prostaglandin actions. It also inhibits platelet aggregation and prolongs bleeding time.**Indications for Ibuprofen*1.Rheumatoid arthritis *2.Ankylosing spondylitis *3.Acute gout *4.Joint disorders e.g. inflammatory disease in joints, crystal deposition in the joints *5.Osteoarthritis *6.For the relief of fever, pain and inflammation in dental, minor surgery and orthopedic *7.Dysmenorrhoea *8.Juvenile arthritis *9.Migraine *10.Patent ductus arteriosus(IV)
ULTRAFEN 100 mg/5ml 120ml susp.IBUPROFENGLAXO SMITHKLINENSAID.Propionic acid derivatives4.8About Ibuprofen*NSAID, a propionic acid derivative, Analgesic and anti-inflammatory.**Mechanism of Action of Ibuprofen*Ibuprofen has analgesic, anti-inflammatory and antipyretic action. It acts by inhibiting Prostaglandin (PGs) synthesis and their release at the site of injury. Prostaglandins cause tenderness and amplify the action of other algesics. Ibuprofen inhibits cyclo-oxygenase enzyme and antagonizes prostaglandin actions. It also inhibits platelet aggregation and prolongs bleeding time.**Indications for Ibuprofen*1.Rheumatoid arthritis *2.Ankylosing spondylitis *3.Acute gout *4.Joint disorders e.g. inflammatory disease in joints, crystal deposition in the joints *5.Osteoarthritis *6.For the relief of fever, pain and inflammation in dental, minor surgery and orthopedic *7.Dysmenorrhoea *8.Juvenile arthritis *9.Migraine *10.Patent ductus arteriosus(IV)
ULTRAFEN 200 mg supp.IBUPROFENGLAXO SMITHKLINENSAID.Propionic acid derivatives4About Ibuprofen*NSAID, a propionic acid derivative, Analgesic and anti-inflammatory.**Mechanism of Action of Ibuprofen*Ibuprofen has analgesic, anti-inflammatory and antipyretic action. It acts by inhibiting Prostaglandin (PGs) synthesis and their release at the site of injury. Prostaglandins cause tenderness and amplify the action of other algesics. Ibuprofen inhibits cyclo-oxygenase enzyme and antagonizes prostaglandin actions. It also inhibits platelet aggregation and prolongs bleeding time.**Indications for Ibuprofen*1.Rheumatoid arthritis *2.Ankylosing spondylitis *3.Acute gout *4.Joint disorders e.g. inflammatory disease in joints, crystal deposition in the joints *5.Osteoarthritis *6.For the relief of fever, pain and inflammation in dental, minor surgery and orthopedic *7.Dysmenorrhoea *8.Juvenile arthritis *9.Migraine *10.Patent ductus arteriosus(IV)
ULTRAFEN 200mg 30tab.IBUPROFENGLAXO SMITHKLINENSAID.Propionic acid derivatives5.6About Ibuprofen*NSAID, a propionic acid derivative, Analgesic and anti-inflammatory.**Mechanism of Action of Ibuprofen*Ibuprofen has analgesic, anti-inflammatory and antipyretic action. It acts by inhibiting Prostaglandin (PGs) synthesis and their release at the site of injury. Prostaglandins cause tenderness and amplify the action of other algesics. Ibuprofen inhibits cyclo-oxygenase enzyme and antagonizes prostaglandin actions. It also inhibits platelet aggregation and prolongs bleeding time.**Indications for Ibuprofen*1.Rheumatoid arthritis *2.Ankylosing spondylitis *3.Acute gout *4.Joint disorders e.g. inflammatory disease in joints, crystal deposition in the joints *5.Osteoarthritis *6.For the relief of fever, pain and inflammation in dental, minor surgery and orthopedic *7.Dysmenorrhoea *8.Juvenile arthritis *9.Migraine *10.Patent ductus arteriosus(IV)
ULTRAFEN 400 mg 20 tab.IBUPROFENGLAXO SMITHKLINENSAID.Propionic acid derivatives9About Ibuprofen*NSAID, a propionic acid derivative, Analgesic and anti-inflammatory.**Mechanism of Action of Ibuprofen*Ibuprofen has analgesic, anti-inflammatory and antipyretic action. It acts by inhibiting Prostaglandin (PGs) synthesis and their release at the site of injury. Prostaglandins cause tenderness and amplify the action of other algesics. Ibuprofen inhibits cyclo-oxygenase enzyme and antagonizes prostaglandin actions. It also inhibits platelet aggregation and prolongs bleeding time.**Indications for Ibuprofen*1.Rheumatoid arthritis *2.Ankylosing spondylitis *3.Acute gout *4.Joint disorders e.g. inflammatory disease in joints, crystal deposition in the joints *5.Osteoarthritis *6.For the relief of fever, pain and inflammation in dental, minor surgery and orthopedic *7.Dysmenorrhoea *8.Juvenile arthritis *9.Migraine *10.Patent ductus arteriosus(IV)
ULTRAFEN 500 mg supp.IBUPROFENGLAXO SMITHKLINENSAID.Propionic acid derivatives5About Ibuprofen*NSAID, a propionic acid derivative, Analgesic and anti-inflammatory.**Mechanism of Action of Ibuprofen*Ibuprofen has analgesic, anti-inflammatory and antipyretic action. It acts by inhibiting Prostaglandin (PGs) synthesis and their release at the site of injury. Prostaglandins cause tenderness and amplify the action of other algesics. Ibuprofen inhibits cyclo-oxygenase enzyme and antagonizes prostaglandin actions. It also inhibits platelet aggregation and prolongs bleeding time.**Indications for Ibuprofen*1.Rheumatoid arthritis *2.Ankylosing spondylitis *3.Acute gout *4.Joint disorders e.g. inflammatory disease in joints, crystal deposition in the joints *5.Osteoarthritis *6.For the relief of fever, pain and inflammation in dental, minor surgery and orthopedic *7.Dysmenorrhoea *8.Juvenile arthritis *9.Migraine *10.Patent ductus arteriosus(IV)
ULTRAFEN 600 mg 20 tab.IBUPROFENGLAXO SMITHKLINENSAID.Propionic acid derivatives12About Ibuprofen*NSAID, a propionic acid derivative, Analgesic and anti-inflammatory.**Mechanism of Action of Ibuprofen*Ibuprofen has analgesic, anti-inflammatory and antipyretic action. It acts by inhibiting Prostaglandin (PGs) synthesis and their release at the site of injury. Prostaglandins cause tenderness and amplify the action of other algesics. Ibuprofen inhibits cyclo-oxygenase enzyme and antagonizes prostaglandin actions. It also inhibits platelet aggregation and prolongs bleeding time.**Indications for Ibuprofen*1.Rheumatoid arthritis *2.Ankylosing spondylitis *3.Acute gout *4.Joint disorders e.g. inflammatory disease in joints, crystal deposition in the joints *5.Osteoarthritis *6.For the relief of fever, pain and inflammation in dental, minor surgery and orthopedic *7.Dysmenorrhoea *8.Juvenile arthritis *9.Migraine *10.Patent ductus arteriosus(IV)
VALTREX 500mg 42 tab.VALACYCLOVIRGLAXO SMITHKLINEAnti-Viral.Nucleoside385"Indication For the treatment or suppression of cold sores (herpes labialis), herpes zoster (shingles), genital herpes in immunocompetent individuals, and recurrent genital herpes in HIV-infected individuals.*Mechanism of action Valaciclovir is phosphorylated by viral thymidine kinase to acyclovir triphosphate (the active metabolite) which then inhibits herpes viral DNA replication by competitive inhibition of viral DNA polymerase, and by incorporation into and termination of the growing viral DNA chain. When used as a substrate for viral DNA polymerase, acyclovir triphosphate competitively inhibits dATP leading to the formation of faulty DNA. This is where acyclovir triphosphate is incorporated into the DNA strand replacing many of the adenosine bases. This results in the prevention of DNA synthesis, as phosphodiester bridges can longer to be built, destabilizing the strand."
VENTOLIN 0.5% respirator solution 20 MLSALBUTAMOLGLAXO SMITHKLINE33About Salbutamol*Beta2-Adrenergic Agonist, Phenethylamine derivative, Bronchodilator(Antiasthma), uterine relaxant.*Mechanism of Action of Salbutamol*Salbutamol is a short acting ?2 receptor agonist. It selectively stimulates ?2 receptors present in airway, Uterus, and Vascular Smooth muscles. It directly relaxes the airway smooth muscles and produces bronchodilation. Stimulation of ?2 receptors activates Gs adenylyl-cyclase -cyclic AMP path way and produces reduction in smooth muscle tone. ?2 receptor agonists also increases the conductance of large Ca2 -- sensitive K -- channels in airway smooth muscles and leads to membrane hyperpolarisation and relaxation of smooth muscles. *?2 receptor agonists also suppress the release of Leukotrienes and histamine from the mast cells in the lung tissue and enhance mucociliary function and decrease micro vascular permeability and also inhibits Phospholipase A2 which produces inhibition of prostaglandins production.
VENTOLIN 2mg 20 tab.SALBUTAMOLGLAXO SMITHKLINE8About Salbutamol*Beta2-Adrenergic Agonist, Phenethylamine derivative, Bronchodilator(Antiasthma), uterine relaxant.*Mechanism of Action of Salbutamol*Salbutamol is a short acting ?2 receptor agonist. It selectively stimulates ?2 receptors present in airway, Uterus, and Vascular Smooth muscles. It directly relaxes the airway smooth muscles and produces bronchodilation. Stimulation of ?2 receptors activates Gs adenylyl-cyclase -cyclic AMP path way and produces reduction in smooth muscle tone. ?2 receptor agonists also increases the conductance of large Ca2 -- sensitive K -- channels in airway smooth muscles and leads to membrane hyperpolarisation and relaxation of smooth muscles. *?2 receptor agonists also suppress the release of Leukotrienes and histamine from the mast cells in the lung tissue and enhance mucociliary function and decrease micro vascular permeability and also inhibits Phospholipase A2 which produces inhibition of prostaglandins production.
VENTOLIN 2mg/5ml 125ml syrupSALBUTAMOLGLAXO SMITHKLINE9About Salbutamol*Beta2-Adrenergic Agonist, Phenethylamine derivative, Bronchodilator(Antiasthma), uterine relaxant.*Mechanism of Action of Salbutamol*Salbutamol is a short acting ?2 receptor agonist. It selectively stimulates ?2 receptors present in airway, Uterus, and Vascular Smooth muscles. It directly relaxes the airway smooth muscles and produces bronchodilation. Stimulation of ?2 receptors activates Gs adenylyl-cyclase -cyclic AMP path way and produces reduction in smooth muscle tone. ?2 receptor agonists also increases the conductance of large Ca2 -- sensitive K -- channels in airway smooth muscles and leads to membrane hyperpolarisation and relaxation of smooth muscles. *?2 receptor agonists also suppress the release of Leukotrienes and histamine from the mast cells in the lung tissue and enhance mucociliary function and decrease micro vascular permeability and also inhibits Phospholipase A2 which produces inhibition of prostaglandins production.
VENTOLIN DISKUS 200mcg/dose accuhalerSALBUTAMOLGLAXO SMITHKLINE32.5About Salbutamol*Beta2-Adrenergic Agonist, Phenethylamine derivative, Bronchodilator(Antiasthma), uterine relaxant.*Mechanism of Action of Salbutamol*Salbutamol is a short acting ?2 receptor agonist. It selectively stimulates ?2 receptors present in airway, Uterus, and Vascular Smooth muscles. It directly relaxes the airway smooth muscles and produces bronchodilation. Stimulation of ?2 receptors activates Gs adenylyl-cyclase -cyclic AMP path way and produces reduction in smooth muscle tone. ?2 receptor agonists also increases the conductance of large Ca2 -- sensitive K -- channels in airway smooth muscles and leads to membrane hyperpolarisation and relaxation of smooth muscles. *?2 receptor agonists also suppress the release of Leukotrienes and histamine from the mast cells in the lung tissue and enhance mucociliary function and decrease micro vascular permeability and also inhibits Phospholipase A2 which produces inhibition of prostaglandins production.
VENTOLIN EVOHALER 100mcg/actuation inhalerSALBUTAMOLGLAXO SMITHKLINE23.5About Salbutamol*Beta2-Adrenergic Agonist, Phenethylamine derivative, Bronchodilator(Antiasthma), uterine relaxant.*Mechanism of Action of Salbutamol*Salbutamol is a short acting ?2 receptor agonist. It selectively stimulates ?2 receptors present in airway, Uterus, and Vascular Smooth muscles. It directly relaxes the airway smooth muscles and produces bronchodilation. Stimulation of ?2 receptors activates Gs adenylyl-cyclase -cyclic AMP path way and produces reduction in smooth muscle tone. ?2 receptor agonists also increases the conductance of large Ca2 -- sensitive K -- channels in airway smooth muscles and leads to membrane hyperpolarisation and relaxation of smooth muscles. *?2 receptor agonists also suppress the release of Leukotrienes and histamine from the mast cells in the lung tissue and enhance mucociliary function and decrease micro vascular permeability and also inhibits Phospholipase A2 which produces inhibition of prostaglandins production.
VENTOLIN EXPECTORANT 125ml syrupGUAIFENESIN -- SALBUTAMOLGLAXO SMITHKLINE10.5"Description *An expectorant that also has some muscle relaxing action*Mechanism of action Guaifenesin may act as an irritant to gastric vagal receptors, and recruit efferent parasympathetic reflexes that cause glandular exocytosis of a less viscous mucus mixture. Cough may be provoked. This combination may flush tenacious, congealed mucopurulent material from obstructed small airways and lead to a temporary improvement in dyspnea or the work of breathing."
VENTOLIN ROTACAPS 200 MCG 8*16 INH. CAPS.SALBUTAMOLGLAXO SMITHKLINE79About Salbutamol*Beta2-Adrenergic Agonist, Phenethylamine derivative, Bronchodilator(Antiasthma), uterine relaxant.*Mechanism of Action of Salbutamol*Salbutamol is a short acting ?2 receptor agonist. It selectively stimulates ?2 receptors present in airway, Uterus, and Vascular Smooth muscles. It directly relaxes the airway smooth muscles and produces bronchodilation. Stimulation of ?2 receptors activates Gs adenylyl-cyclase -cyclic AMP path way and produces reduction in smooth muscle tone. ?2 receptor agonists also increases the conductance of large Ca2 -- sensitive K -- channels in airway smooth muscles and leads to membrane hyperpolarisation and relaxation of smooth muscles. *?2 receptor agonists also suppress the release of Leukotrienes and histamine from the mast cells in the lung tissue and enhance mucociliary function and decrease micro vascular permeability and also inhibits Phospholipase A2 which produces inhibition of prostaglandins production.
VERM-ALL 100mg 6tab.FLUBENDAZOLEGLAXO SMITHKLINEAnthelmintic4.5Indication:*Flubendazol is used in the treatment of single or mixed infections caused by: Enterobiasis, ascariasis, hookworm, and trichuriasis *Contraindications:*Hypersensitivity to the drug Pregnancy and Lactation*Side effects:*Flubendazol is well tolerated but may cause: transient abdominal pain, diarrhea, headache, allergic reactions and raised liver enzyme values with the high doses.*Dosage and administration:*For the treatment of enterobiasis:*Adults and children: l00mgas a single dose repeated if necessary after 2-3 weeks.*For ascariasis, hook worm, and Trichuriasis: l00mg twice daily for 3 days
VERM-ALL 100mg/5ml susp. 30 MLFLUBENDAZOLEGLAXO SMITHKLINEAnthelmintic4.75Indication:*Flubendazol is used in the treatment of single or mixed infections caused by: Enterobiasis, ascariasis, hookworm, and trichuriasis *Contraindications:*Hypersensitivity to the drug Pregnancy and Lactation*Side effects:*Flubendazol is well tolerated but may cause: transient abdominal pain, diarrhea, headache, allergic reactions and raised liver enzyme values with the high doses.*Dosage and administration:*For the treatment of enterobiasis:*Adults and children: l00mgas a single dose repeated if necessary after 2-3 weeks.*For ascariasis, hook worm, and Trichuriasis: l00mg twice daily for 3 days
VITAMAX 30 CAPSULESMINERALS -- VITAMINSGLAXO SMITHKLINEMulti-Vitamins.Comination43.25
VITAMAX PLUS 20 CAPSMINERALS -- VITAMINSGLAXO SMITHKLINEMulti-Vitamins.Comination45
VOTRIENT 200 MG 30 F.C. TAB.PAZOPANIBGLAXO SMITHKLINE2380It is a potent and selective multi-targeted receptor tyrosine kinase inhibitor that blocks tumour growth and inhibits angiogenesis. It has been approved for renal cell carcinoma and soft tissue sarcoma by numerous regulatory administrations worldwide.
VOTRIENT 400 MG 30 F.C. TAB.PAZOPANIBGLAXO SMITHKLINE4387It is a potent and selective multi-targeted receptor tyrosine kinase inhibitor that blocks tumour growth and inhibits angiogenesis. It has been approved for renal cell carcinoma and soft tissue sarcoma by numerous regulatory administrations worldwide.
WELLBUTRIN 150mg S.R.tab.BUPROPIONGLAXO SMITHKLINEpsychiatric.Antidepressants70About Bupropion*Norepinephrine and dopamine reuptake inhibitor,nicotinic antagonist, aminoketone derivative, Atypical antidepressant, Smoking Cessation Aid.*Mechanism of Action of Bupropion*Bupropion blocks the re-uptake of neurotransmitter Dopamine and Noradrenaline from the synapse in to the presynaptic nerve terminal in the CNS. It has only a less activity in blocking the reuptake of Serotonin. Bupropion potentiates the noradrenergic and Dopaminergic activity and produces antidepressant activity. *Smoking cessation action: Bupropion is a competitive antagonist of nicotine. *Indications for Bupropion*1. Depression *2. Smoking cessation treatment
ZANTAC 150mg 2*10 EFF. Tab.RANITIDINEGLAXO SMITHKLINEPeptic Ulcer.Anti-Histamine.H2 Antagonist43.25About Ranitidine*A histamine H2-receptor antagonist, Furan derivative, Anti-secretory G.I agent,Anti ulcer.*Mechanism of Action of Ranitidine*Ranitidine is a H2 (Histamine) receptor antagonist. Histamine is the most potent stimulus of acid secretion and acts as the common mediator. H2 receptor is a G-protein coupled receptor. It induces adenylate cyclase which converts ATP to cyclic AMP. This cyclic AMP acts on proton pump and exchange extracellular potassium ion for intracellular hydrogen ion across the parietal cell membrane. Ranitidine reversibly competes with Histamine for binding to H2 receptors on the parietal cells and predominantly inhibits basal acid secretion. *Anaesthetic adjuncts: It is used in patients undergoing prolonged operations, caesarian section,obese patients those are at increased risk of gastric regurgitation and aspiration pneumonia. It raises pH of gastric juice and also reduces its volume and thus chances of regurgitation.
ZANTAC 150mg 20 F.C.tab.RANITIDINEGLAXO SMITHKLINEPeptic Ulcer.Anti-Histamine.H2 Antagonist36About Ranitidine*A histamine H2-receptor antagonist, Furan derivative, Anti-secretory G.I agent,Anti ulcer.*Mechanism of Action of Ranitidine*Ranitidine is a H2 (Histamine) receptor antagonist. Histamine is the most potent stimulus of acid secretion and acts as the common mediator. H2 receptor is a G-protein coupled receptor. It induces adenylate cyclase which converts ATP to cyclic AMP. This cyclic AMP acts on proton pump and exchange extracellular potassium ion for intracellular hydrogen ion across the parietal cell membrane. Ranitidine reversibly competes with Histamine for binding to H2 receptors on the parietal cells and predominantly inhibits basal acid secretion. *Anaesthetic adjuncts: It is used in patients undergoing prolonged operations, caesarian section,obese patients those are at increased risk of gastric regurgitation and aspiration pneumonia. It raises pH of gastric juice and also reduces its volume and thus chances of regurgitation.
ZANTAC 300mg 20 F.C.tab.RANITIDINEGLAXO SMITHKLINEPeptic Ulcer.Anti-Histamine.H2 Antagonist54About Ranitidine*A histamine H2-receptor antagonist, Furan derivative, Anti-secretory G.I agent,Anti ulcer.*Mechanism of Action of Ranitidine*Ranitidine is a H2 (Histamine) receptor antagonist. Histamine is the most potent stimulus of acid secretion and acts as the common mediator. H2 receptor is a G-protein coupled receptor. It induces adenylate cyclase which converts ATP to cyclic AMP. This cyclic AMP acts on proton pump and exchange extracellular potassium ion for intracellular hydrogen ion across the parietal cell membrane. Ranitidine reversibly competes with Histamine for binding to H2 receptors on the parietal cells and predominantly inhibits basal acid secretion. *Anaesthetic adjuncts: It is used in patients undergoing prolonged operations, caesarian section,obese patients those are at increased risk of gastric regurgitation and aspiration pneumonia. It raises pH of gastric juice and also reduces its volume and thus chances of regurgitation.
ZINACEF 1.5g I.V. vial.CEFUROXIMEGLAXO SMITHKLINEAntibiotic.cephalosporin.Second-generation33.85About Cefuroxime*Second Generation Cephalosporin antibiotic.**Mechanism of Action of Cefuroxime*Cefuroxime is a 2nd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefuroxime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefuroxime **Indications for Cefuroxime*1.Meningitis caused by H.influenzae, meningococci, pneumococci etc. *2.Gonorrhea *3.Pneumonia & Pulmonary infections *4.Infections caused by ampicillin resistant H. influenzae *5.Septicemia *6.Tonsillitis *7.Pharyngitis *8.Urinary tract infections *9.Otitis media
ZINACEF 125mg 10 F.C. TABS.CEFUROXIMEGLAXO SMITHKLINEAntibiotic.cephalosporin.Second-generation18About Cefuroxime*Second Generation Cephalosporin antibiotic.**Mechanism of Action of Cefuroxime*Cefuroxime is a 2nd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefuroxime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefuroxime **Indications for Cefuroxime*1.Meningitis caused by H.influenzae, meningococci, pneumococci etc. *2.Gonorrhea *3.Pneumonia & Pulmonary infections *4.Infections caused by ampicillin resistant H. influenzae *5.Septicemia *6.Tonsillitis *7.Pharyngitis *8.Urinary tract infections *9.Otitis media
ZINACEF 125mg/5ml 50ml susp.CEFUROXIMEGLAXO SMITHKLINEAntibiotic.cephalosporin.Second-generation22.2About Cefuroxime*Second Generation Cephalosporin antibiotic.**Mechanism of Action of Cefuroxime*Cefuroxime is a 2nd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefuroxime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefuroxime **Indications for Cefuroxime*1.Meningitis caused by H.influenzae, meningococci, pneumococci etc. *2.Gonorrhea *3.Pneumonia & Pulmonary infections *4.Infections caused by ampicillin resistant H. influenzae *5.Septicemia *6.Tonsillitis *7.Pharyngitis *8.Urinary tract infections *9.Otitis media
ZINACEF 250mg 10 F.C. TABS.CEFUROXIMEGLAXO SMITHKLINEAntibiotic.cephalosporin.Second-generation30About Cefuroxime*Second Generation Cephalosporin antibiotic.**Mechanism of Action of Cefuroxime*Cefuroxime is a 2nd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefuroxime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefuroxime **Indications for Cefuroxime*1.Meningitis caused by H.influenzae, meningococci, pneumococci etc. *2.Gonorrhea *3.Pneumonia & Pulmonary infections *4.Infections caused by ampicillin resistant H. influenzae *5.Septicemia *6.Tonsillitis *7.Pharyngitis *8.Urinary tract infections *9.Otitis media
ZINACEF 250mg vial.CEFUROXIMEGLAXO SMITHKLINEAntibiotic.cephalosporin.Second-generation8.5About Cefuroxime*Second Generation Cephalosporin antibiotic.**Mechanism of Action of Cefuroxime*Cefuroxime is a 2nd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefuroxime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefuroxime **Indications for Cefuroxime*1.Meningitis caused by H.influenzae, meningococci, pneumococci etc. *2.Gonorrhea *3.Pneumonia & Pulmonary infections *4.Infections caused by ampicillin resistant H. influenzae *5.Septicemia *6.Tonsillitis *7.Pharyngitis *8.Urinary tract infections *9.Otitis media
ZINACEF 500mg 10 F.C. TABS.CEFUROXIMEGLAXO SMITHKLINEAntibiotic.cephalosporin.Second-generation45About Cefuroxime*Second Generation Cephalosporin antibiotic.**Mechanism of Action of Cefuroxime*Cefuroxime is a 2nd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefuroxime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefuroxime **Indications for Cefuroxime*1.Meningitis caused by H.influenzae, meningococci, pneumococci etc. *2.Gonorrhea *3.Pneumonia & Pulmonary infections *4.Infections caused by ampicillin resistant H. influenzae *5.Septicemia *6.Tonsillitis *7.Pharyngitis *8.Urinary tract infections *9.Otitis media
ZINACEF 750mg I.V/I.M vialCEFUROXIMEGLAXO SMITHKLINEAntibiotic.cephalosporin.Second-generation18.15About Cefuroxime*Second Generation Cephalosporin antibiotic.**Mechanism of Action of Cefuroxime*Cefuroxime is a 2nd generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefuroxime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefuroxime **Indications for Cefuroxime*1.Meningitis caused by H.influenzae, meningococci, pneumococci etc. *2.Gonorrhea *3.Pneumonia & Pulmonary infections *4.Infections caused by ampicillin resistant H. influenzae *5.Septicemia *6.Tonsillitis *7.Pharyngitis *8.Urinary tract infections *9.Otitis media
ZOFRAN 4mg/2ml 5 amp. For I.V/I.M inj.ONDANSETRONGLAXO SMITHKLINE137.55About Ondansetron*Selective serotonin 5-HT3 receptor antagonist, Imidazole derivative, Antiemetic.*Mechanism of Action of Ondansetron*Ondansetron is a selective 5HT3 receptor antagonist. 5HT3 receptors are present in vagal nerve terminals and chemoreceptor trigger zone of area postrema of the brain. *Cytotoxic chemotherapy is associated with release of Serotonin from Enterochromaffin cells in the small intestine. Serotonin triggers vomiting through 5HT3 vagal receptor that activates the vomiting reflex. Since Ondansetron is a 5HT3 receptor antagonist, it is indicated for the prevention of nausea and vomiting associated in chemotherapy. *Anaesthetic adjuncts: It is used preoperatively in order to reduce the post operative vomiting.
ZOFRAN 8mg 10 tab.ONDANSETRONGLAXO SMITHKLINE364About Ondansetron*Selective serotonin 5-HT3 receptor antagonist, Imidazole derivative, Antiemetic.*Mechanism of Action of Ondansetron*Ondansetron is a selective 5HT3 receptor antagonist. 5HT3 receptors are present in vagal nerve terminals and chemoreceptor trigger zone of area postrema of the brain. *Cytotoxic chemotherapy is associated with release of Serotonin from Enterochromaffin cells in the small intestine. Serotonin triggers vomiting through 5HT3 vagal receptor that activates the vomiting reflex. Since Ondansetron is a 5HT3 receptor antagonist, it is indicated for the prevention of nausea and vomiting associated in chemotherapy. *Anaesthetic adjuncts: It is used preoperatively in order to reduce the post operative vomiting.
ZOFRAN 8mg/4ml 5 amp. For I.V./I.M. inj.ONDANSETRONGLAXO SMITHKLINE260About Ondansetron*Selective serotonin 5-HT3 receptor antagonist, Imidazole derivative, Antiemetic.*Mechanism of Action of Ondansetron*Ondansetron is a selective 5HT3 receptor antagonist. 5HT3 receptors are present in vagal nerve terminals and chemoreceptor trigger zone of area postrema of the brain. *Cytotoxic chemotherapy is associated with release of Serotonin from Enterochromaffin cells in the small intestine. Serotonin triggers vomiting through 5HT3 vagal receptor that activates the vomiting reflex. Since Ondansetron is a 5HT3 receptor antagonist, it is indicated for the prevention of nausea and vomiting associated in chemotherapy. *Anaesthetic adjuncts: It is used preoperatively in order to reduce the post operative vomiting.
ZOVIRAX 200mg/5ml 125ml susp.ACYCLOVIRGLAXO SMITHKLINEAnti-Viral.Nucleoside143.05(Indications) : *This medication is an antiviral agent, prescribed for herpes simplex, genital herpes, herpes zoster and chickenpox. It slows down the growth and spread of the herpes virus. Acyclovir is also sometimes used to treat eczema herpeticum, herpes infections of the skin, eyes, nose, and mouth in patients with human immunodeficiency virus (HIV) . ** (Dosage) : *Acute Treatment of Herpes Zoster: 800 mg every 4 hours orally, 5 times daily for 7 to 10 days. *Genital Herpes: Treatment of Initial Genital Herpes: 200 mg every 4 hours, 5 times daily for 10 days. *Chronic Suppressive Therapy for Recurrent Disease: 400 mg 2 times daily for up to 12 months, followed by re-evaluation. *Treatment of Chickenpox: Children (2 years of age and older): 20 mg/kg per dose orally 4 times daily (80 mg/kg/day) for 5 days. *Adults and Children over 40 kg: 800 mg 4 times daily for 5 days. **
ZOVIRAX 250mg I.V. infusionACYCLOVIRGLAXO SMITHKLINEAnti-Viral.Nucleoside64.4(Indications) : *This medication is an antiviral agent, prescribed for herpes simplex, genital herpes, herpes zoster and chickenpox. It slows down the growth and spread of the herpes virus. Acyclovir is also sometimes used to treat eczema herpeticum, herpes infections of the skin, eyes, nose, and mouth in patients with human immunodeficiency virus (HIV) . ** (Dosage) : *Acute Treatment of Herpes Zoster: 800 mg every 4 hours orally, 5 times daily for 7 to 10 days. *Genital Herpes: Treatment of Initial Genital Herpes: 200 mg every 4 hours, 5 times daily for 10 days. *Chronic Suppressive Therapy for Recurrent Disease: 400 mg 2 times daily for up to 12 months, followed by re-evaluation. *Treatment of Chickenpox: Children (2 years of age and older): 20 mg/kg per dose orally 4 times daily (80 mg/kg/day) for 5 days. *Adults and Children over 40 kg: 800 mg 4 times daily for 5 days. **
ZOVIRAX 3% 4.5gram eye.oint.ACYCLOVIRGLAXO SMITHKLINEAnti-Viral.Nucleoside31.75(Indications) : *This medication is an antiviral agent, prescribed for herpes simplex, genital herpes, herpes zoster and chickenpox. It slows down the growth and spread of the herpes virus. Acyclovir is also sometimes used to treat eczema herpeticum, herpes infections of the skin, eyes, nose, and mouth in patients with human immunodeficiency virus (HIV) . ** (Dosage) : *Acute Treatment of Herpes Zoster: 800 mg every 4 hours orally, 5 times daily for 7 to 10 days. *Genital Herpes: Treatment of Initial Genital Herpes: 200 mg every 4 hours, 5 times daily for 10 days. *Chronic Suppressive Therapy for Recurrent Disease: 400 mg 2 times daily for up to 12 months, followed by re-evaluation. *Treatment of Chickenpox: Children (2 years of age and older): 20 mg/kg per dose orally 4 times daily (80 mg/kg/day) for 5 days. *Adults and Children over 40 kg: 800 mg 4 times daily for 5 days. **
ZOVIRAX 400mg 10 tab.ACYCLOVIRGLAXO SMITHKLINEAnti-Viral.Nucleoside33(Indications) : *This medication is an antiviral agent, prescribed for herpes simplex, genital herpes, herpes zoster and chickenpox. It slows down the growth and spread of the herpes virus. Acyclovir is also sometimes used to treat eczema herpeticum, herpes infections of the skin, eyes, nose, and mouth in patients with human immunodeficiency virus (HIV) . ** (Dosage) : *Acute Treatment of Herpes Zoster: 800 mg every 4 hours orally, 5 times daily for 7 to 10 days. *Genital Herpes: Treatment of Initial Genital Herpes: 200 mg every 4 hours, 5 times daily for 10 days. *Chronic Suppressive Therapy for Recurrent Disease: 400 mg 2 times daily for up to 12 months, followed by re-evaluation. *Treatment of Chickenpox: Children (2 years of age and older): 20 mg/kg per dose orally 4 times daily (80 mg/kg/day) for 5 days. *Adults and Children over 40 kg: 800 mg 4 times daily for 5 days. **
ZOVIRAX 5% topical cream 10 GMACYCLOVIRGLAXO SMITHKLINEAnti-Viral.Nucleoside14.4(Indications) : *This medication is an antiviral agent, prescribed for herpes simplex, genital herpes, herpes zoster and chickenpox. It slows down the growth and spread of the herpes virus. Acyclovir is also sometimes used to treat eczema herpeticum, herpes infections of the skin, eyes, nose, and mouth in patients with human immunodeficiency virus (HIV) . ** (Dosage) : *Acute Treatment of Herpes Zoster: 800 mg every 4 hours orally, 5 times daily for 7 to 10 days. *Genital Herpes: Treatment of Initial Genital Herpes: 200 mg every 4 hours, 5 times daily for 10 days. *Chronic Suppressive Therapy for Recurrent Disease: 400 mg 2 times daily for up to 12 months, followed by re-evaluation. *Treatment of Chickenpox: Children (2 years of age and older): 20 mg/kg per dose orally 4 times daily (80 mg/kg/day) for 5 days. *Adults and Children over 40 kg: 800 mg 4 times daily for 5 days. **
ZOVIRAX 500 mg freez dried powder for infusionACYCLOVIRGLAXO SMITHKLINEAnti-Viral.Nucleoside80(Indications) : *This medication is an antiviral agent, prescribed for herpes simplex, genital herpes, herpes zoster and chickenpox. It slows down the growth and spread of the herpes virus. Acyclovir is also sometimes used to treat eczema herpeticum, herpes infections of the skin, eyes, nose, and mouth in patients with human immunodeficiency virus (HIV) . ** (Dosage) : *Acute Treatment of Herpes Zoster: 800 mg every 4 hours orally, 5 times daily for 7 to 10 days. *Genital Herpes: Treatment of Initial Genital Herpes: 200 mg every 4 hours, 5 times daily for 10 days. *Chronic Suppressive Therapy for Recurrent Disease: 400 mg 2 times daily for up to 12 months, followed by re-evaluation. *Treatment of Chickenpox: Children (2 years of age and older): 20 mg/kg per dose orally 4 times daily (80 mg/kg/day) for 5 days. *Adults and Children over 40 kg: 800 mg 4 times daily for 5 days. **
ZOVIRAX D.S 400mg/5ml 100ml susp.ACYCLOVIRGLAXO SMITHKLINEAnti-Viral.Nucleoside47(Indications) : *This medication is an antiviral agent, prescribed for herpes simplex, genital herpes, herpes zoster and chickenpox. It slows down the growth and spread of the herpes virus. Acyclovir is also sometimes used to treat eczema herpeticum, herpes infections of the skin, eyes, nose, and mouth in patients with human immunodeficiency virus (HIV) . ** (Dosage) : *Acute Treatment of Herpes Zoster: 800 mg every 4 hours orally, 5 times daily for 7 to 10 days. *Genital Herpes: Treatment of Initial Genital Herpes: 200 mg every 4 hours, 5 times daily for 10 days. *Chronic Suppressive Therapy for Recurrent Disease: 400 mg 2 times daily for up to 12 months, followed by re-evaluation. *Treatment of Chickenpox: Children (2 years of age and older): 20 mg/kg per dose orally 4 times daily (80 mg/kg/day) for 5 days. *Adults and Children over 40 kg: 800 mg 4 times daily for 5 days. **
ZYLORIC 100mg 30 tab.ALLOPURINOLGLAXO SMITHKLINEAntigout.Xanthine oxidase inhibitor16.25Description*Xanthine oxidase inhibitor, In hyperuricemia in gout or during cancer chemotherapy.**Mechanism of Action of Allopurinol*It inhibits an enzyme xanthine oxidase that is necessary to form uric acid (the enzyme catalyzing the conversion of hypoxanthine to xanthine, and xanthine to uric acid), a substance present in abnormally large amounts in the blood of persons with gout that forms solid deposits in the joints, the kidneys, and other tissues**Indications for Allopurinol*1. Primary hyperuricaemia of Gout. *2. Secondary hyperuricaemia due to myeloid metaplasia, radiation, cancer chemotherapy, thiazide diuretics. *3. Prevention of uric acid nephropathy. **Contra-indications of Allopurinol*1. Hypersensitivity to the drug. *2. Acute gout. *3. Hemochromatosis. ****
ZYLORIC 300mg 30 tab.ALLOPURINOLGLAXO SMITHKLINEAntigout.Xanthine oxidase inhibitor24.25Description*Xanthine oxidase inhibitor, In hyperuricemia in gout or during cancer chemotherapy.**Mechanism of Action of Allopurinol*It inhibits an enzyme xanthine oxidase that is necessary to form uric acid (the enzyme catalyzing the conversion of hypoxanthine to xanthine, and xanthine to uric acid), a substance present in abnormally large amounts in the blood of persons with gout that forms solid deposits in the joints, the kidneys, and other tissues**Indications for Allopurinol*1. Primary hyperuricaemia of Gout. *2. Secondary hyperuricaemia due to myeloid metaplasia, radiation, cancer chemotherapy, thiazide diuretics. *3. Prevention of uric acid nephropathy. **Contra-indications of Allopurinol*1. Hypersensitivity to the drug. *2. Acute gout. *3. Hemochromatosis. ****
ZYRTEC 0.1% 100ml syrupCETIRIZINEGLAXO SMITHKLINEAnti-histamine.Anti-Allergy20About Cetirizine*Second Generation H1 Antagonist, Metabolite of hydroxyzine, Antihistamine.**Mechanism of Action of Cetirizine*This drug is a selective peripheral H1 receptor antagonist. Thus it inhibits the allergic symptoms produced by histamines like cold, rhinorrhea, sneezing, urticaria etc. The drug has some mast cell stabilizing properties. It also inhibit eotaxin-induced eosinophil TEM through both dermal and lung micro vascular endothelial cells. So inhibit eosinophil chemotaxis and also inflammation caused by it.**Indications for Cetirizine*1. Sneezing *2. Rhinorrhoea *3. Postnasal discharge. *4. Common coughs *5. Colds. *6. Chronic urticaria *7. Dermatitis *8. Pruritic skin disorders *9. Hay fever *10. Angioedema
ZYRTEC 10 mg 20 tab.CETIRIZINEGLAXO SMITHKLINEAnti-histamine.Anti-Allergy39.75About Cetirizine*Second Generation H1 Antagonist, Metabolite of hydroxyzine, Antihistamine.**Mechanism of Action of Cetirizine*This drug is a selective peripheral H1 receptor antagonist. Thus it inhibits the allergic symptoms produced by histamines like cold, rhinorrhea, sneezing, urticaria etc. The drug has some mast cell stabilizing properties. It also inhibit eotaxin-induced eosinophil TEM through both dermal and lung micro vascular endothelial cells. So inhibit eosinophil chemotaxis and also inflammation caused by it.**Indications for Cetirizine*1. Sneezing *2. Rhinorrhoea *3. Postnasal discharge. *4. Common coughs *5. Colds. *6. Chronic urticaria *7. Dermatitis *8. Pruritic skin disorders *9. Hay fever *10. Angioedema
ZYRTEC 10mg/ml oral dropsCETIRIZINEGLAXO SMITHKLINEAnti-histamine.Anti-Allergy18About Cetirizine*Second Generation H1 Antagonist, Metabolite of hydroxyzine, Antihistamine.**Mechanism of Action of Cetirizine*This drug is a selective peripheral H1 receptor antagonist. Thus it inhibits the allergic symptoms produced by histamines like cold, rhinorrhea, sneezing, urticaria etc. The drug has some mast cell stabilizing properties. It also inhibit eotaxin-induced eosinophil TEM through both dermal and lung micro vascular endothelial cells. So inhibit eosinophil chemotaxis and also inflammation caused by it.**Indications for Cetirizine*1. Sneezing *2. Rhinorrhoea *3. Postnasal discharge. *4. Common coughs *5. Colds. *6. Chronic urticaria *7. Dermatitis *8. Pruritic skin disorders *9. Hay fever *10. Angioedema
NAVIDOXINE 10 TABLETS (ILLEGAL IMPORT)MECLIZINE -- VITAMIN B6GLAXO SMITHKLINE -0About Meclizine*First Generation H1 Antagonist, Piperazine derivative, Antihistamine, antiemetic, antinauseant.*Mechanism of Action of Meclizine*Meclizine produces Antiemetic action by its central action on Chemoreceptor trigger zone (CTZ). It decreases the sensitivity of Labyrinth apparatus which transmit stimuli to the CTZ and stimulates the vomiting center. *Meclizine produces antivertigo action by decreasing the excitability of middle ear labyrinth. It blocks the conduction in the middle ear vestibular path ways. *Meclizine is a potent H1 receptor antihistaminic agent. It has anticholinergic activity also *About Vit B6*Physiological functions: It is involved as a coenzyme (Pyridoxal phosphate) in metabolism of tryptophan, in several metabolic transformations of amino acids including transamination, decarboxylation & racemization. *Deficiency symptoms: Peripheral neuritis, seizures, stomatitis, glossitis, anaemia, seborrhea like lesions.*

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