EVA Pharm

Company Information

History :

Established in 1997, Eva Pharma is one of Egypt's leading pharmaceutical companies, built on the heritage of Les Laboratoires Delta, Egypt's second oldest pharmaceutical company.Today, Eva Pharma is the fastest growing pharmaceutical company in the MENA region, growing at a rate of more than 30% CAGR (compound annual growth rate) for the past seven years; transforming from a successful local company into a world class multinational organization, with a sales and marketing presence across the region.Eva Pharma is an active contributor to the on-going drug industry in Egypt, North Africa and the Middle East, with huge market participation.Currently, Eva Pharma consists of a team of 2811 loyal staff and produces an average 350,000 effective and affordable packs of medicine daily from 137 different products. All our products are stamped by several recognized quality seals and the Eva Pharma logo which, due to our exacting quality standards, acts as our own stamp of approval.


Vision
Empower the fight for health and wellbeing as a Human right
Mission:
To save and improve millions of lives in Africa and frontier markets by offering accessible, high quality branded medicines that meet specific local market needs through innovative research & product development, a passionate diverse top team and state of the art scale facilities.
Values:
Our Values At Eva Pharma we pride ourselves on our core values and ethics that have guided our growth and helped position us as one of the most trusted providers of healthcare products in Egypt and the region. The founding pillars of our philosophy, is to improve people's lives by honoring our core values:- Customer First- Ownership- Passion for Success- Honesty- Fairness- Respect- Positive Impact.


Logo

  • No. of Employees: 500 +

  • Range of expected salary for Med. Rep.: After interview

  • Car policy: Yes

  • Incentive scheme: yes

  • factory: yes

  • Company rank (IMS) 2018: 7

  • Company link: http://www.evapharma.com

Products

Trade NameGeneric NameCompanyPharmacology PriceDescription
ACNETROX 1% TOPICAL CREAM 25 GMNADIFLOXACINEVA PHARMAAntibiotic.quinolone24Nadifloxacin is a topical fluoroquinolone antibiotic for the treatment of acne vulgaris. It is also used to treat bacterial skin infections.**Nadifloxacin inhibits the enzyme DNA gyrase that is involved in bacterial DNA synthesis and replication, thus inhibiting the bacterial multiplication. Nadifloxacin in addition to determine a therapeutic antibacterial action, can have a sebostatic and anti-inflammatory action, thus contributing to the improvement of the clinical condition of the patient.
ACNIDU topical gelBENZOYL PEROXIDE--ERYTHROMYCINEVA PHARMA16.2COMPOSITION:*When dispensed, ACNIDU (erythromycin and benzoyl peroxide topical gel, USP) contains:Container (1) 5% (50 mg/g) benzoyl peroxide*Container (2) 3% (30 mg/g) erythromycin*Container (3) Ethyl alcohol .**INDICATIONS:*Acnidu is indicated for the topical treatment of acne vulgaris.**DOSAGE:*Acnidu Topical Gel should be applied twice daily, morning and evening, or as directed by a physician, to affected areas after the skin is thoroughly washed. rinsed with warm water and gently patted dry.**PACKAGE:*Carton box containing 3 containers (2 plastic containers and 1 glass vial)**STORAGE:*Before reconstitution store at temperature dose not exceeding 30 C.After reconstitution: store under refrigeration between 2-8 C.
AMLOVERAN 10/10mg 30 tabs.AMLODIPINE -- PERINDOPRILEVA PHARMAAnti-hypertensive.Combined ACE with calcium channel blocker120"Indication *For the treatment of mild to moderate essential hypertension, mild to moderate congestive heart failure, and to reduce the cardiovascular risk of individuals with hypertension or post-myocardial infarction and stable coronary disease.**About Amlodipine*Calcium Channel Blocker, Anti hypertensive,anti angina.**Mechanism of Action of Amlodipine*Amlodipine is a second generation dihydropyridine Ca channel blocker. It exerts it`s antihypertensive, antianginal actions through blocking the influx of Ca ions through voltage gated L-type Ca channels to the peripheral vascular smooth muscle cells, Coronary smooth muscle cells and to the myocardial cells. Thus causes dilatation of vascular endothelium, decrease peripheral resistance, & reduce myocardial oxygen demand .It markedly relax arterioles and milder effects on veins. They do not compromise haemodynamics and cerebral and renal perfusion.**Indications :*1.Hypertension *2.Prinzmetal`s angina *3.Stable angina"
AMLOVERAN 10/5mg 30 tabs.AMLODIPINE -- PERINDOPRILEVA PHARMAAnti-hypertensive.Combined ACE with calcium channel blocker111"Indication *For the treatment of mild to moderate essential hypertension, mild to moderate congestive heart failure, and to reduce the cardiovascular risk of individuals with hypertension or post-myocardial infarction and stable coronary disease.**About Amlodipine*Calcium Channel Blocker, Anti hypertensive,anti angina.**Mechanism of Action of Amlodipine*Amlodipine is a second generation dihydropyridine Ca channel blocker. It exerts it`s antihypertensive, antianginal actions through blocking the influx of Ca ions through voltage gated L-type Ca channels to the peripheral vascular smooth muscle cells, Coronary smooth muscle cells and to the myocardial cells. Thus causes dilatation of vascular endothelium, decrease peripheral resistance, & reduce myocardial oxygen demand .It markedly relax arterioles and milder effects on veins. They do not compromise haemodynamics and cerebral and renal perfusion.**Indications :*1.Hypertension *2.Prinzmetal`s angina *3.Stable angina"
AMLOVERAN 5/10mg 30 tabs.AMLODIPINE -- PERINDOPRILEVA PHARMAAnti-hypertensive.Combined ACE with calcium channel blocker84"Indication *For the treatment of mild to moderate essential hypertension, mild to moderate congestive heart failure, and to reduce the cardiovascular risk of individuals with hypertension or post-myocardial infarction and stable coronary disease.**About Amlodipine*Calcium Channel Blocker, Anti hypertensive,anti angina.**Mechanism of Action of Amlodipine*Amlodipine is a second generation dihydropyridine Ca channel blocker. It exerts it`s antihypertensive, antianginal actions through blocking the influx of Ca ions through voltage gated L-type Ca channels to the peripheral vascular smooth muscle cells, Coronary smooth muscle cells and to the myocardial cells. Thus causes dilatation of vascular endothelium, decrease peripheral resistance, & reduce myocardial oxygen demand .It markedly relax arterioles and milder effects on veins. They do not compromise haemodynamics and cerebral and renal perfusion.**Indications :*1.Hypertension *2.Prinzmetal`s angina *3.Stable angina"
AMLOVERAN 5/5mg 30 tabs.AMLODIPINE -- PERINDOPRILEVA PHARMAAnti-hypertensive.Combined ACE with calcium channel blocker78"Indication *For the treatment of mild to moderate essential hypertension, mild to moderate congestive heart failure, and to reduce the cardiovascular risk of individuals with hypertension or post-myocardial infarction and stable coronary disease.**About Amlodipine*Calcium Channel Blocker, Anti hypertensive,anti angina.**Mechanism of Action of Amlodipine*Amlodipine is a second generation dihydropyridine Ca channel blocker. It exerts it`s antihypertensive, antianginal actions through blocking the influx of Ca ions through voltage gated L-type Ca channels to the peripheral vascular smooth muscle cells, Coronary smooth muscle cells and to the myocardial cells. Thus causes dilatation of vascular endothelium, decrease peripheral resistance, & reduce myocardial oxygen demand .It markedly relax arterioles and milder effects on veins. They do not compromise haemodynamics and cerebral and renal perfusion.**Indications :*1.Hypertension *2.Prinzmetal`s angina *3.Stable angina"
APHTHTAB 2mg 20 Buccal bioadhesive tab.AMLEXANOXEVA PHARMAMouth Ulcer..Antiallergic.Anti-inflammatory46"Description : *Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and rhinitis. Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers. Recurrent aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and 50% of the general population.**Indication :*Used as a paste in the mouth to treat aphthous ulcers**Mechanism of action :*amlexanox has anti-inflammatory and antiallergic properties. It inhibits chemical mediatory release of the slow-reacting substance of anaphylaxis (SRS-A) and may have antagonistic effects on interleukin-3. When cells are under stress, they release an inactive form of human fibroblast growth factor 1 (FGF-1), a potent mitogen (entity that causes mitosis). Amlexanox binds to FGF1, increasing its conformational stability, sterically blocking Cu(2) induced oxidation which normally leads to activation of FGF-1."
APIXATRACK 2.5 MG 10 F.C. TABS.APIXABANEVA PHARMAAnticoagulant97Apixaban is an anticoagulant for the treatment of venous thromboembolic events. It is taken by mouth. It is a direct factor Xa inhibitor.*Apixaban was approved in the U.S. in 2014 for treatment and secondary prophylaxis of deep vein thrombosis (DVT) and pulmonary embolism (PE).**Apixaban is indicated for the following:**To lower the risk of stroke and embolism in patients with nonvalvular atrial fibrillation.**Deep vein thrombosis (DVT) prophylaxis. DVT s may lead to pulmonary embolism (PE) in knee or hip replacement surgery patients.**Treatment of both DVT and PE.**To reduce the risk of recurring DVT and PE after initial therapy.
ARTHFREE 100mg 3f.c.tab.LEFLUNOMIDEEVA PHARMAImmunosuppressive Agent.Antirheumatic Antiviral Agent.pyrimidine synthesis inhibitor60About Leflunomide*A pyrimidine synthesis inhibitor, Isoxazole derivative, Disease-modifying Antirheumatic Drug.**Mechanism of Action of Leflunomide*This immunomodulatory drug inhibits dihydroorotate dehydrogenase (an enzyme involved in de novo pyrimidine synthesis) (abbreviation DHODH). It also has anti-inflammatory effect. This double action is slow progression of the disease and to cause remission/relief of symptoms of rheumatoid arthritis and psoriatic arthritis such as joint tenderness and decreased joint and general mobility in human patients.**Indications for Leflunomide*1. Rheumatoid arthritis *2. Psoriatic arthritis *Interactions for Leflunomide*Cholesturamine, charcoal: Co-administration with lefulnomide results in rapid and significant decrease in lefulnomide activity. *Rifampicin: Co-administration increases lefulnomide plasma levels. *Hepatotoxic drugs: Co-administration may increase side effects. *NSAIDs: increase in the free fraction of diclofenac and ibuprof
ARTHFREE 20mg 10f.c.tab.LEFLUNOMIDEEVA PHARMAImmunosuppressive Agent.Antirheumatic Antiviral Agent.pyrimidine synthesis inhibitor50About Leflunomide*A pyrimidine synthesis inhibitor, Isoxazole derivative, Disease-modifying Antirheumatic Drug.**Mechanism of Action of Leflunomide*This immunomodulatory drug inhibits dihydroorotate dehydrogenase (an enzyme involved in de novo pyrimidine synthesis) (abbreviation DHODH). It also has anti-inflammatory effect. This double action is slow progression of the disease and to cause remission/relief of symptoms of rheumatoid arthritis and psoriatic arthritis such as joint tenderness and decreased joint and general mobility in human patients.**Indications for Leflunomide*1. Rheumatoid arthritis *2. Psoriatic arthritis *Interactions for Leflunomide*Cholesturamine, charcoal: Co-administration with lefulnomide results in rapid and significant decrease in lefulnomide activity. *Rifampicin: Co-administration increases lefulnomide plasma levels. *Hepatotoxic drugs: Co-administration may increase side effects. *NSAIDs: increase in the free fraction of diclofenac and ibuprof
BACTIZOLID 100mg/5ml 150ml suspLINEZOLIDEVA PHARMAAntibiotic.Oxazolidinone38.75About Linezolid*Oxazolidinone derivative, reversible, nonselective monoamine oxidase inhibitor, Antibiotic.**Mechanism of Action of Linezolid*Linezolid binds to the 23 S fraction of 50 S ribosome and inhibit the formation of 70S initiation complex. **Indications for Linezolid*1.Skin and soft tissue infection *2.Pneumonia *3.Wound infection *4.Bactremia *5.Respiratory tract infection *6.Septicaemia *7.Vancomycin resistant enterococcal infection**Typical Dosage for Linezolid*Adult: 800 - 1200 mg/day in two divided dose for 1 - 2 week
BIOVITONE 24 CAPSULESGINSENG -- WHEAT GERM OIL -- EVENING PRIMROSE OIL -- YEAST CONCENTRATE -- VITAMIN C -- ZINC SULPHATEEVA PHARMA25.2
BONPROVE 150 MG 3 F.C. TABLETSIBANDRONIC ACIDEVA PHARMAOsteoporosis.Antiresorptives66Dose : one tablet 150 mg taken once monthly on the same date each month
BOSENTADIN 125 MG 10 F.C. TABS.BOSENTANEVA PHARMA699Pharmacology**Endothelian receptor antagonist that blocks endothelin receptors on endothelium and vascular smooth muscle (stimulation of these receptors is associated with vasoconstriction). Bosentan blocks both ETA and ETB receptors, with a slightly higher affinity for the A subtype. **Indications**Pulmonary arterial hypertension: Treatment of pulmonary artery hypertension (PAH) (WHO Group I) in patients with WHO/NYHA Class II, III, or IV symptoms to improve exercise capacity and decrease the rate of clinical deterioration. Note: According to treatment guidelines from the Fifth World Symposium on Pulmonary Hypertension (WSPH), only a small number of PAH patients with WHO-FC IV symptoms (ie, severely ill patients) were included in clinical trials, therefore, most experts consider bosentan second-line therapy in these patients (WSPH [Gailï؟½ 2013]).
BOSENTADIN 62.5 MG 10 F.C. TABS.BOSENTANEVA PHARMA699Pharmacology**Endothelian receptor antagonist that blocks endothelin receptors on endothelium and vascular smooth muscle (stimulation of these receptors is associated with vasoconstriction). Bosentan blocks both ETA and ETB receptors, with a slightly higher affinity for the A subtype. **Indications**Pulmonary arterial hypertension: Treatment of pulmonary artery hypertension (PAH) (WHO Group I) in patients with WHO/NYHA Class II, III, or IV symptoms to improve exercise capacity and decrease the rate of clinical deterioration. Note: According to treatment guidelines from the Fifth World Symposium on Pulmonary Hypertension (WSPH), only a small number of PAH patients with WHO-FC IV symptoms (ie, severely ill patients) were included in clinical trials, therefore, most experts consider bosentan second-line therapy in these patients (WSPH [Gailï؟½ 2013]).
BUSPALEX 15mg 24 tabs.BUSPIRONEEVA PHARMApsychiatric.Anxiolytics-hypnotics24About Buspirone*Psychotropic drug, serotonin 5-HT1A receptor partial agonist, weak Dopamine (D2) antagonist azaspirodecanediones derivative, Sedative, anxiolytic agent.**Mechanism of Action of Buspirone*Buspirone has a partial agonistic action on 5HT1A receptor and it stimulates presynaptic autoreceptors. This will produce a decrease in serotonin neuronal activity. It also has antagonistic action on post synaptic 5HT1A receptor. Buspirone has a weak Dopamine (D2) antagonistic action. Mood elevation may be due to facilitation of noradrenergic system.**Indications for Buspirone*Anxiety**Typical Dosage for Buspirone*Adult: 15 - 30 mg / day in 3 divided dose *Initial dose: 15 mg / day in 3 divided dose. Dose can be gradually increased in every 3 days. Maximum daily dose: 60 mg / day
CALAMIDINE TOPICAL LOTION 120 MLCALAMINE -- DIPHENHYDRAMINE -- ZINC OXIDEEVA PHARMA4.95
CALSTER 250 MG 30 CHEW. TABS.CALCIUMEVA PHARMACalcium Supplement18.75Treating or preventing calcium deficiency. It may also be used for other conditions as determined by your doctor.SSCalcium carbonate is a dietary supplement. It works by providing extra calcium to the body.SSDo NOT use calcium carbonate if:SSyou are allergic to any ingredient in calcium carbonateSyou have high blood calcium levels
CALSTER 500 MG 30 F.C. TABS.CALCIUMEVA PHARMACalcium Supplement24Treating or preventing calcium deficiency. It may also be used for other conditions as determined by your doctor.**Calcium carbonate is a dietary supplement. It works by providing extra calcium to the body.**Do NOT use calcium carbonate if:**you are allergic to any ingredient in calcium carbonate*you have high blood calcium levels
CARNIVITA 30% Oral SolutionL-CARNITINEEVA PHARMAvitamin33About L-carnitine*Dietary supplement, Amino acid derivative, Antioxidant.**Mechanism of Action of L-carnitine*Carnitine is an essential co-factor of fatty acid metabolism in the heart, liver, and skeletal muscle. It is normally synthesised in the liver, brain, and kidneys in sufficient quantities to meet human requirements. It is an antioxidant. It protects neurons from damage caused by super oxide radicals.**Indications for L-carnitine*1.As antioxidant *2.Carnitine deficiency
CARNIVITA FORTE 30 F.C. Tab.L-CARNITINE L-TARTRATE -- ZINCEVA PHARMA92.5About L-carnitine*Dietary supplement, Amino acid derivative, Antioxidant.*Mechanism of Action of L-carnitine*Carnitine is an essential co-factor of fatty acid metabolism in the heart, liver, and skeletal muscle. It is normally synthesised in the liver, brain, and kidneys in sufficient quantities to meet human requirements. It is an antioxidant. It protects neurons from damage caused by super oxide radicals.*Indications for L-carnitine*1.As antioxidant *2.Carnitine deficiency *Typical Dosage for L-carnitine*Oral .. Adult: 100 - 200 mg/kg daily in 2 to 4 divided doses. *Children: 50 to 100 mg/kg daily in 2 to 4 divided doses *Parenteral (IV) SAdult: 50 to 100 mg/kg daily is given in 3 to 4 divided doses by slow intravenous injection over 2 to 3 minutes.
CHROMAX 60 CAPSULESCHROMIUM PICOLINATE -- GARCINIA CAMBOGIA FRUIT EXTRACTEVA PHARMA79During weight loss programs
CITRA 20 LOZENGESVITAMIN C -- ZINC GLUCONATEEVA PHARMA14
CLINDANOID Topical Gel 30 GMCLINDAMYCIN -- TRETINOINEVA PHARMA9
CLOVIRALEX 600 MG 10 TABLETSEFAVIRENZEVA PHARMAAnti-Viral200It is a non-nucleoside reverse transcriptase inhibitor (NNRTI) discovered at Merck Research Laboratories. It is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1.
CLOXIDE 30Caps.CHLORDIAZEPOXIDE -- CLIDINIUM BROMIDEEVA PHARMA6.5(chlordiazepoxide and clidinium) combines in a single capsule formulation the antianxiety action of chlordiazepoxide hydrochloride and the anticholinergic/spasmolytic effects of clidinium bromide.*Chlordiazepoxide hydrochloride is a versatile, therapeutic agent of proven value for the relief of anxiety and tension. It is indicated when anxiety, tension or apprehension are significant components of the clinical profile. It is among the safer of the effective psychopharmacologic compounds.*Clidinium bromide is a synthetic anticholinergic agent which has been shown in experimental and clinical studies to have a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract.
COLDEX-2 18 F.C.tab.CAFFEINE -- CHLORPHENIRAMINE -- PARACETAMOL(ACETAMINOPHEN) -- PSEUDOEPHEDRINEEVA PHARMA8"Description *A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma.*Indication For the treatment of rhinitis, urticaria, allergy, common cold, asthma and hay fever.*Pharmacodynamics In allergic reactions an allergen interacts with and cross-links surface IgE antibodies on mast cells and basophils. Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell-degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. Once released, histamine can react with local or widespread tissues through histamine receptors. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Chlorpheniramine, is a histamine H1 antagonist (or more correctly, an inverse histamine agonist) of the alkylamine class."
CONVENTIN 100mg 30 cap.GABAPENTINEVA PHARMAAnti-epileptic.GABA analogs27.75About Gabapentin*A GABA analogue, Anticonvulsant, Mood stabilizer.**Mechanism of Action of Gabapentin*Gabapentin is a GABA derivative and it bounds to lipophilic molecule. The mechanism of action of Gabapentin is not exactly known. It crosses blood brain barrier and enhances release of GABA.**Indications for Gabapentin*1.Antiepileptic(Treatment of partial seizure) *2.Treatment of neuropathic pain **Typical Dosage for Gabapentin*Adult: Initial dose: 300 mg / day increase the dose by 300 mg/day for next 2 days (up to 900 mg / day in 3 divided doses). Thereafter increase the dose until sufficient therapeutic response is obtained. *Maintenance dose: 900-1800mg /day in 3 divided doses *Maximum dose: 3.6 g /day *Children above 12 years: 10mg / kg / day in 3 divided doses, then gradually increase the dose until sufficient therapeutic response is obtained.
CONVENTIN 300mg 30 Caps.GABAPENTINEVA PHARMAAnti-epileptic.GABA analogs60About Gabapentin*A GABA analogue, Anticonvulsant, Mood stabilizer.**Mechanism of Action of Gabapentin*Gabapentin is a GABA derivative and it bounds to lipophilic molecule. The mechanism of action of Gabapentin is not exactly known. It crosses blood brain barrier and enhances release of GABA.**Indications for Gabapentin*1.Antiepileptic(Treatment of partial seizure) *2.Treatment of neuropathic pain **Typical Dosage for Gabapentin*Adult: Initial dose: 300 mg / day increase the dose by 300 mg/day for next 2 days (up to 900 mg / day in 3 divided doses). Thereafter increase the dose until sufficient therapeutic response is obtained. *Maintenance dose: 900-1800mg /day in 3 divided doses *Maximum dose: 3.6 g /day *Children above 12 years: 10mg / kg / day in 3 divided doses, then gradually increase the dose until sufficient therapeutic response is obtained.
CONVENTIN 400mg 30 Caps.GABAPENTINEVA PHARMAAnti-epileptic.GABA analogs81About Gabapentin*A GABA analogue, Anticonvulsant, Mood stabilizer.**Mechanism of Action of Gabapentin*Gabapentin is a GABA derivative and it bounds to lipophilic molecule. The mechanism of action of Gabapentin is not exactly known. It crosses blood brain barrier and enhances release of GABA.**Indications for Gabapentin*1.Antiepileptic(Treatment of partial seizure) *2.Treatment of neuropathic pain **Typical Dosage for Gabapentin*Adult: Initial dose: 300 mg / day increase the dose by 300 mg/day for next 2 days (up to 900 mg / day in 3 divided doses). Thereafter increase the dose until sufficient therapeutic response is obtained. *Maintenance dose: 900-1800mg /day in 3 divided doses *Maximum dose: 3.6 g /day *Children above 12 years: 10mg / kg / day in 3 divided doses, then gradually increase the dose until sufficient therapeutic response is obtained.
CURAZOLE 2% topical cream 15 GMKETOCONAZOLEEVA PHARMAantifungals.Imidazoles7About Ketoconazole*Imidazole derivative, A broad spectrum Antifungal.**Mechanism of Action of Ketoconazole*Ketoconazole is fungicidal or fungistatic depending on concentrations. I t inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochromeP450 enzyme 14 alpha demethylase and impair ergosterol synthesis. This will alter cell membrane and its permeability. This will results in loss of intracellular components. It also inhibits biosynthesis of triglycerides and phospholipids by fungi. It also inhibits several enzymes (e.g. Oxidative and peroxidative enzymes) which are involved in detoxification process. This will leads to cellular necrosis. **Interactions for Ketoconazole*Antacids & Histamine H2 antagonists: Increased gastric pH may inhibit ketoconazole absorption. *Isoniazid: The bioavailability of Ketoconazole may be decreased. *Rifampicin: Decreased serum levels of either drug may occur. **
CURAZOLE-H shampoo 60 MLCHLORHEXIDINE -- KETOCONAZOLEEVA PHARMA14.4
CYMBATEX 20mg 30 hard gelatin Caps.DULOXETINEEVA PHARMApsychiatric.Antidepressants126About Duloxetine*A serotonin-norepinephrine reuptake inhibitor,Thiophene derivative, Antidepressant.**Mechanism of Action of Duloxetine*Duloxetine preferentially inhibits the re-uptake of Noradrenaline and Serotonin (5 HT) in the CNS nerve terminals .This will result in an increased concentration of neurotransmitter Serotonin in the synaptic cleft and produces antidepressant effect**Indications for Duloxetine*1. Major depressive disorder *2. Diabetic Peripheral Neuropathic Pain *3. Generalised anxiety disorder **Typical Dosage for Duloxetine*Major Depressive Disorder: 20 - 60mg / day in 2 divided doses *Diabetic Peripheral Neuropathic Pain:60 mg/day *Generalized Anxiety Disorder: 60 mg/ day
CYMBATEX 30mg 30 hard gelatin Caps.DULOXETINEEVA PHARMApsychiatric.Antidepressants166About Duloxetine*A serotonin-norepinephrine reuptake inhibitor,Thiophene derivative, Antidepressant.**Mechanism of Action of Duloxetine*Duloxetine preferentially inhibits the re-uptake of Noradrenaline and Serotonin (5 HT) in the CNS nerve terminals .This will result in an increased concentration of neurotransmitter Serotonin in the synaptic cleft and produces antidepressant effect**Indications for Duloxetine*1. Major depressive disorder *2. Diabetic Peripheral Neuropathic Pain *3. Generalised anxiety disorder **Typical Dosage for Duloxetine*Major Depressive Disorder: 20 - 60mg / day in 2 divided doses *Diabetic Peripheral Neuropathic Pain:60 mg/day *Generalized Anxiety Disorder: 60 mg/ day
CYMBATEX 60mg 30 hard gelatin Caps.DULOXETINEEVA PHARMApsychiatric.Antidepressants214.5About Duloxetine*A serotonin-norepinephrine reuptake inhibitor,Thiophene derivative, Antidepressant.**Mechanism of Action of Duloxetine*Duloxetine preferentially inhibits the re-uptake of Noradrenaline and Serotonin (5 HT) in the CNS nerve terminals .This will result in an increased concentration of neurotransmitter Serotonin in the synaptic cleft and produces antidepressant effect**Indications for Duloxetine*1. Major depressive disorder *2. Diabetic Peripheral Neuropathic Pain *3. Generalised anxiety disorder **Typical Dosage for Duloxetine*Major Depressive Disorder: 20 - 60mg / day in 2 divided doses *Diabetic Peripheral Neuropathic Pain:60 mg/day *Generalized Anxiety Disorder: 60 mg/ day
DACLAVIRIDIN 60 MG 28 F.C. TABS.DACLATASVIREVA PHARMAAnti-Viral200*Daclatasvir is a drug for the treatment of hepatitis C (HCV).**Daclatasvir inhibits the HCV nonstructural protein NS5A. Recent research suggests that it targets two steps of the viral replication process, enabling rapid decline of HCV RNA.**Daclatasvir has been tested in combination regimens with pegylated interferon and ribavirin, as well as with other direct-acting antiviral agents including asunaprevir and sofosbuvir.
DESLORAT 0.5mg/ml 100ml syrupDESLORATADINEEVA PHARMAAnti-histamine.Anti-Allergy9About Desloratadine*Second Generation long-acting tricyclic H1 Antagonist, Antihistamine.**Mechanism of Action of Desloratadine*This second generation antihistamine has a selective peripheral H1-antagonist action.Desloratadine competes with free histamine for binding at H1-receptors in the GI tract, uterus, large blood vessels, and bronchial smooth muscle. This inhibit the action of histamine, which subsequently leads to temporary relief of the negative symptoms brought by histamine**Indications for Desloratadine*1. Hay fever *2. Watery eyes *3. Runny nose *4. Itching eyes *5. Sneezing *6. Hives *7. Decongestant **Typical Dosage for Desloratadine**Adult (general dose)- 5mg/day *Children (-12yrs)-Same as adult
DESLORAT 5mg 20 F.C. Tab.DESLORATADINEEVA PHARMAAnti-histamine.Anti-Allergy20About Desloratadine*Second Generation long-acting tricyclic H1 Antagonist, Antihistamine.**Mechanism of Action of Desloratadine*This second generation antihistamine has a selective peripheral H1-antagonist action.Desloratadine competes with free histamine for binding at H1-receptors in the GI tract, uterus, large blood vessels, and bronchial smooth muscle. This inhibit the action of histamine, which subsequently leads to temporary relief of the negative symptoms brought by histamine**Indications for Desloratadine*1. Hay fever *2. Watery eyes *3. Runny nose *4. Itching eyes *5. Sneezing *6. Hives *7. Decongestant **Typical Dosage for Desloratadine**Adult (general dose)- 5mg/day *Children (-12yrs)-Same as adult
DIACEREIN 50mg 30 cap.DIACERINEVA PHARMA92.5(Indications) : *This medication is an anti-inflammatory agent, prescribed for osteoarthritis and chronic inflammatory arthritis. It works by inhibiting interleukin-1. **Dosage & When it is to be taken : *Osteoarthritis- Adult-PO- The recommended dose is 50 mg to be taken twice daily. **Warnings and Precautions : Caution should be exercised in patients with history of liver, kidney disease, during pregnancy and breastfeeding. *Monitor complete blood count, liver function, and urinalysis regularly while taking this medication. **Side Effects : Diarrhea, stomach pain, nausea, vomiting and intense yellow coloring of urine. **
DIAMONRECTA 20mg 2 F.C. Tab.TADALAFILEVA PHARMASexual tonic50About Tadalafil*A Phosphodiesterase 5 enzyme inhibitor, Treating erectile dysfunction (ED).*Mechanism of Action of Tadalafil*Tadalafil is a phosphodiesterase enzyme (PDE5) inhibitor. This enzyme is responsible for the degradation cyclic guanosine monophosphate (cGMP) produced in reaction to sexual stimulation. The more cGMP is available, the more durable the erection. Tadalafil inhibits the PDE5 enzyme, preserving cGMP levels, therefore aiding erection viability and durability *Erection of the penis is caused by the filling of the penis with blood. Filling occurs because the blood vessels that bring blood to the penis increase in size and deliver more blood to the penis, and, at the same time, the blood vessels that take blood away from the penis decrease in size and remove less blood from the penis. *Sexual stimulation that leads to an erection causes the production and release of nitric oxide in the penis. The nitric oxide causes an enzyme, guanylate cyclase,
Diety 300 TabsASPARTAMEEVA PHARMA15
Diety 50 TabsASPARTAMEEVA PHARMA4
DIMETROL 100ml susp.DILOXANIDE FUROATE -- METRONIDAZOLEEVA PHARMAAntiprotozoal.Nitroimidazole5.5"About Diloxanide Furoate*Dichloroacetamide derivative, anti-protozoal, Luminal amebicides.*Mechanism of Action of Diloxanide Furoate*Diloxanide Furoate is a dicloroacetamide derivative which acts as a luminal amoebicide. It exerts its action by directly killing the trophozoites responsible for production of cysts.**Indications for Diloxanide Furoate*1. Mild intestinal Amoebiasis, *2. Asymptomatic cyst passers of Entamoeba histolitica **Mechanism of action Metronidazole *is a prodrug. Unionized metronidazole is selective for anaerobic bacteria due to their ability to intracellularly reduce metronidazole to its active form. This reduced metronidazole then covalently binds to DNA, disrupt its helical structure, inhibiting bacterial nucleic acid synthesis and resulting in bacterial cell death."
DIMETROL-N 20 F.C.tab.DILOXANIDE FUROATE -- MEBEVERINE -- METRONIDAZOLEEVA PHARMA14About Diloxanide Furoate*Dichloroacetamide derivative, anti-protozoal, Luminal amebicides.*Mechanism of Action of Diloxanide Furoate*Diloxanide Furoate is a dicloroacetamide derivative which acts as a luminal amoebicide. It exerts its action by directly killing the trophozoites responsible for production of cysts*Indications for Diloxanide Furoate*1. Mild intestinal Amoebiasis, *2. Asymptomatic cyst passers of Entamoeba histolitica *Interactions for Diloxanide Furoate*No known interaction.*Typical Dosage for Diloxanide Furoate*Adults: 0.5gm 8hourly for 5 to 10days. *Children (above 2years): 20mg/kg/day in divided doses up to 10days.
DONAZIL 5mg 30 F.C.tab.DONEPEZILEVA PHARMA63About Donepezil*Central Acetylcholinesterase inhibitor, Antidementia agent in Alzheimer`s disease.**Mechanism of Action of Donepezil*Alzheimer`s disease may result from a deficiency in neurotransmitters used by nerves in the brain to communicate with one another. Donepezil exerts its therapeutic effect by enhancing its cholinergic function. It increases the concentration of Acetylcholine through reversible inhibition of acetyl cholinesterase enzyme which is involved in the hydrolysis of Acetylcholine. It leads to increased concentration of Acetylcholine.This increased Acetylcholine concentrations are believed to be responsible for the improvement seen during treatment with donepezil.**Interactions for Donepezil*Antiarrhythmics: Procainamide, quinidine and probably propafenone antagonise effect of neostigmine & pyridostigmine. *Antibacterials : Aminoglycosides, clindamycin & colistin antagonise effect of neostigmine & pyridostigmine. *Antimuscarinics: Antagonism of effect. *
DONIFOXATE 40 MG 30 F.C. TABLETSFEBUXOSTATEVA PHARMAAntigout73.25Indication: treatment of hyperuricaemia in conditions where urate deposition has already occured.*Dose: 1 tablet once daily
DONIFOXATE 80 MG 30 F.C. TABLETSFEBUXOSTATEVA PHARMAAntigout85.75Indication: treatment of hyperuricaemia in conditions where urate deposition has already occured.*Dose: 1 tablet once daily
DRONADEX 400 MG 10 TABS.DRONEDARONEEVA PHARMA52Dronedarone mainly for the indication of cardiac arrhythmias. It was recommended as an alternative to amiodarone for the treatment of atrial fibrillation and atrial flutter in people whose hearts have either returned to normal rhythm or who undergo drug therapy or electric shock treatment i.e. direct current cardioversion (DCCV) to maintain normal rhythm.*Dronedarone has been termed a ï؟½multichannel blockerï؟½ however it is unclear which channel(s) play a pivotal role in its success.
DROTAVEX 200mg 36 Caps.NIFUROXAZIDEEVA PHARMA15Indications**Infectious diarrhea in children and adults, chronic colitis, enterocolitis, as an adjunctive treatment in combined therapy of intestinal dysbiosis.**Contraindication**Hypersensitivity to 5-nitrofurane derivatives and/or other components of the drug.**Dosage and administration**Nifuroxazide should be taken orally, with or without meals.**Adults and children over 6 years of age - 1 tablet 4 times daily (a daily dose - 800 mg).**The treatment course is 5 - 7 days.*Side effects**Nifuroxazide is well tolerated- however, the following effects may be occasionally observed:**gastrointestinal disorders: short-term abdominal pain, nausea, aggravation of diarrhea.**Hypersensitivity reactions (require discontinuation of the drug):**respiratory disorders: asthma-**skin disorders: rash, pruritus.
EMEDROTEC 3mg 20 Buccal Bioadhesive tab.PROCHLORPERAZINEEVA PHARMApsychiatric.Antipsychotics16About Prochlorperazine*First-Generation Antipsychotic, Phenothiazine derivative, Antiemetic, Antipsychotic,anxiolytic.*Mechanism of Action of Prochlorperazine*Antipsychotic action: Prochlorperazine binds to the dopamine receptor (D1, D2, D3 &D4).It exerts its antipsychotic activity by blocking the dopamine projections in the limbic system and in mesocortical area. Peripherally and centrally it acts as a competitive Dopamine antagonist. Prochlorperazine also produces alpha adrenergic blocking activity and anticholinergic activity. It also produces weak H1 antihistaminic activity and anti serotonin activity. *Antiemetic action: Antiemetic activity is by blocking dopamine receptor (D2 receptor) in the Chemoreceptor trigger zone (CTZ) *Migraine: Prochlorperazine has been used in migraine to control severe nausea and vomiting unresponsive to Antiemetics and to relieve the pain of severe migraine attacks unresponsive to parenteral Dihydroergotamine or Sumatriptan. *
ESOMELODAN 20mg 20 enteric coated tab.ESOMEPRAZOLEEVA PHARMAPeptic Ulcer.proton pump inhibitor63About Esomeprazole*A proton pump inhibitor, Substituted Benzimidazole, Antiulcer, antisecretory drug.**Mechanism of Action of Esomeprazole*Esomeprazole is the S enantiomer of Omeprazole and is a proton pump inhibitor. It is a prodrug. After administration it diffuses in to the parietal cell of the stomach and accumulates in the secretory canaliculi. In the acidic medium Esomeprazole is converted to sulfenamide. This sulfenamide covalently interacts with sulfhydryl (SH) group in the proton pump (H -- K -- ATPase) and inhibits the exchange of extracellular K -- for intracellular H -- ion. Esomeprazole irreversibly inhibits proton pumps activity and decreases gastric acid secretion. As compared to Omeprazole, Esomeprazole produces better control of intragastric acidity in Gastroesophageal reflux diseases. It is as effective as Omeprazole in other disease condition.**Indications for Esomeprazole*1.Gastric ulcer *2.Gastroesophageal reflux disease *3.Oesophagitis *4.NSAID associated ulcerat
ESOMELODAN 40mg 20 enteric coated tab.ESOMEPRAZOLEEVA PHARMAPeptic Ulcer.proton pump inhibitor69About Esomeprazole*A proton pump inhibitor, Substituted Benzimidazole, Antiulcer, antisecretory drug.**Mechanism of Action of Esomeprazole*Esomeprazole is the S enantiomer of Omeprazole and is a proton pump inhibitor. It is a prodrug. After administration it diffuses in to the parietal cell of the stomach and accumulates in the secretory canaliculi. In the acidic medium Esomeprazole is converted to sulfenamide. This sulfenamide covalently interacts with sulfhydryl (SH) group in the proton pump (H -- K -- ATPase) and inhibits the exchange of extracellular K -- for intracellular H -- ion. Esomeprazole irreversibly inhibits proton pumps activity and decreases gastric acid secretion. As compared to Omeprazole, Esomeprazole produces better control of intragastric acidity in Gastroesophageal reflux diseases. It is as effective as Omeprazole in other disease condition.**Indications for Esomeprazole*1.Gastric ulcer *2.Gastroesophageal reflux disease *3.Oesophagitis *4.NSAID associated ulcerat
EVA BABY CARE 50GRAM CREAMZINC OXIDEEVA PHARMA9.75For diaper rash
FINORATE 100mg 20 Caps.FENOFIBRATEEVA PHARMAAntihyperlipidemic.Fibrates11About Fenofibrate*Fibric Acid Derivative, PPARa agonist, Antilipemic agent, Antigout.**Mechanism of Action of Fenofibrate*It is prodrug which has greater LDL (low density lipoprotein) cholesterol lowering potential. It lowers circulating triglyceride levels by activating lipoprotein lipase which is a key enzyme in the degradation of VLDL (very low density lipoprotein) cholesterol. This effect is exerted through paroxisome proliferator-activated receptor alpha (PPARalpha) which enhances lipoprotein lipase synthesis and fatty acid oxidation. It also reduces hepatic triglyceride synthesis. It also reduces VLDL levels and increases HDL (high density lipoprotein) cholesterol. The increase in HDL cholesterol is partly due to transfer of surface lipid components from catabolised VLDL to HDL and also due to increased production of HDL apoproteins by liver.
FINORATE RETARD 250mg 20 Caps.FENOFIBRATEEVA PHARMAAntihyperlipidemic.Fibrates22About Fenofibrate*Fibric Acid Derivative, PPARa agonist, Antilipemic agent, Antigout.**Mechanism of Action of Fenofibrate*It is prodrug which has greater LDL (low density lipoprotein) cholesterol lowering potential. It lowers circulating triglyceride levels by activating lipoprotein lipase which is a key enzyme in the degradation of VLDL (very low density lipoprotein) cholesterol. This effect is exerted through paroxisome proliferator-activated receptor alpha (PPARalpha) which enhances lipoprotein lipase synthesis and fatty acid oxidation. It also reduces hepatic triglyceride synthesis. It also reduces VLDL levels and increases HDL (high density lipoprotein) cholesterol. The increase in HDL cholesterol is partly due to transfer of surface lipid components from catabolised VLDL to HDL and also due to increased production of HDL apoproteins by liver.
FIRAMAZIN 0.4mg 30 H.G.Caps.TAMSULOSINEVA PHARMAUrination-difficulty.Alpha Blocker54About TamsulosinSSelective Alpha1a Adrenergic Antagonist , For benign prostatic hyperplasia.SMechanism of Action of TamsulosinSTamsulosin is adrenergic alpha receptor antagonist. It inhibits alpha 1A and alpha 1D subtype receptors. Tamsulosin selectively inhibits alpha 1A receptor in the prostate and leads to relaxation of smooth muscles in the bladder neck and prostate. This will improve urine flow and reduces BPH symptoms. SAdrenergic nerves releases adrenalin which produces contraction of muscles. Tamsulosin is selectively inhibit alpha 1A receptor in the prostate and bladder neck and relaxes the muscles and decrease the obstruction to the flow of urine in prostate hypertrophy. SIndications for TamsulosinS1. Benign Prostatic hyperplasia (BPH) SSSInteractions for TamsulosinSCimetidine: Results in significant decrease in clearance of tamsulosin AUC. SAlpha adrenergic blocking agents: Tamsulosin should not be used in combination with other alpha adrenergics.
FLAMOGUARD XR 150mg 10 extended release Caps.KETOPROFENEVA PHARMANSAID.Propionic acid derivatives7.5About Ketoprofen*NSAID, propionic acid derivative, Analgesic,antipyretic,antiinflammatory.**Mechanism of Action of Ketoprofen*It inhibits cyclo oxygenase enzymes both COX1 and COX2.These cyclooxygenase enzyme catalyses the synthesis of prostaglandins from arachidonic acid in the tissue. These inhibition produces its analgesic, antipyretic and anti inflammatory effects. It can also stabilize the lysosomal membrane. It is a Non Steroidal Anti Inflammatory Drug. It is a propionic acid derivative.**Indications for Ketoprofen*1. Rheumatoid arthritis *2. Osteo arthritis *3. Pain due to dysmenorrhea *4. Treatment for exacerbations of musculo skeletal, periarticular and soft tissue disorders *5. Migraine *6. Gout-Acute attack
FLIX NASAL SPRAY 50 mcg/metered spray doseFLUTICASONE PROPIONATEEVA PHARMAAnti-inflammatory.glucocorticoid.bronchodilator31.2"Description *Fluticasone propionate, a medium-potency synthetic corticosteroid, is used topically to relieve inflammatory and pruritic symptoms of dermatoses and psoriasis, intranasally to manage symptoms of allergic and non-allergic rhinitis, and orally for the treatment of asthma. Fluticasone proprionate is marketed under several different brand names such as Flonaseï؟½. Fluticasone propionate is also available as a combination product of azelastine hydrochloride and fluticasone propionate called Dymistaï؟½. Dymistaï؟½ is indicated in patients over 12 years old for symptomatic relief of seasonal allergic rhinitis.**Indication * is used topically to relieve inflammatory and pruritic symptoms of dermatoses and psoriasis, intranasally to manage symptoms of allergic and non-allergic rhinitis, and orally for the maintenance treatment of asthma as prophylactic therapy and for patients requiring oral corticosteroid therapy for asthma."
FLOPADEX 4 mg 20 CAPSULESSILODOSINEVA PHARMAUrination-difficulty.Alpha Blocker56It s selective alpha 1 A blocker used to treat symptoms associated with (BPH) Benign Prostate Hyperplasia*Recommended dose : Once daily.
FLOPADEX 8 mg 20 CAPSULESSILODOSINEVA PHARMAUrination-difficulty.Alpha Blocker70It s selective alpha 1 A blocker used to treat symptoms associated with (BPH) Benign Prostate Hyperplasia*Recommended dose : Once daily.
FLOXABACT 250mg 5 F.C.tab.LEVOFLOXACINEVA PHARMAAntibiotic.quinolone8About Levofloxacin*Third generation fluoroquinolone (or quinolone), A broad spectrum antiinfective.**Mechanism of Action of Levofloxacin*Levofloxacin is a broad spectrum antibacterial agent. It act by inhibiting the enzyme DNA gyrase (Topoisomerase 2) and Topoisomerase 4.DNA gyrase helps in the formation of a highly condensed three dimensional structure of the DNA by its nicking and closing activity and also by introducing negative supercoil in to the DNA double helix. Levofloxacin inhibits DNA gyrase which results in abnormal linkage between opened DNA and gyrase and negative supercoiling is also impaired. This will inhibits transcription of DNA in to RNA and subsequent protein synthesis.**Indications for Levofloxacin*1.Sinusitis *2.Bronchitis *3.Pneumonia *4.Urinary tract infection *5.Traveler`s diarrhoea *6.Skin and soft tissue infections *7.Urethritis
FLOXABACT 500mg 10 F.C. TABLETSLEVOFLOXACINEVA PHARMAAntibiotic.quinolone20About Levofloxacin*Third generation fluoroquinolone (or quinolone), A broad spectrum antiinfective.**Mechanism of Action of Levofloxacin*Levofloxacin is a broad spectrum antibacterial agent. It act by inhibiting the enzyme DNA gyrase (Topoisomerase 2) and Topoisomerase 4.DNA gyrase helps in the formation of a highly condensed three dimensional structure of the DNA by its nicking and closing activity and also by introducing negative supercoil in to the DNA double helix. Levofloxacin inhibits DNA gyrase which results in abnormal linkage between opened DNA and gyrase and negative supercoiling is also impaired. This will inhibits transcription of DNA in to RNA and subsequent protein synthesis.**Indications for Levofloxacin*1.Sinusitis *2.Bronchitis *3.Pneumonia *4.Urinary tract infection *5.Traveler`s diarrhoea *6.Skin and soft tissue infections *7.Urethritis
FLUMOL 120ml syrupCHLORPHENIRAMINE -- PARACETAMOL(ACETAMINOPHEN) -- PSEUDOEPHEDRINEEVA PHARMA8.25Indication:*runny noses*blocked noses and sinus*sneezing*watery, itchy eyes*sinus pain*fever, headache, body aches & pain**information:*Pseudoephedrine hydrochloride belongs to a group of medicines called sympathomimetic decongestants.*It works by reducing congestion in the upper respiratory tract, including the nose, nasal passages and sinuses, making it easier to breathe.*Chlorpheniramine maleate belongs to a group of medicines called antihistamines . Antihistamines help reduce allergic symptoms by preventing the effects of a substance called histamine. Histamine is produced by the body in response to foreign substances that the body is allergic to.*Paracetamol works to stop the pain messages from getting through to the brain. It also acts in the brain to reduce fever.
FODAVIR 10mg 30 tab.ADEFOVIREVA PHARMAAnti-Viral.Nucleoside225About Adefovir*Antiretroviral Agent, Reverse Transcriptase Inhibitor (Nucleoside)*Mechanism of Action of Adefovir*Adefovir undergoes phosphorylation in the presence of cellular kinase enzyme to Adefovir diphosphate. This Adefovir diphosphate competitively inhibits HBV DNA polymerase and reverse transcriptase enzyme by competing with nucleoside adenosine triphosphate and inhibits DNA synthesis.*Indications for Adefovir*1.Hepatitis B infection
FUSIDERM 2% cream 15 GMFUSIDIC ACIDEVA PHARMA12About Fusidic acid*A bacteriostatic Steroid Antibiotic, Systemic antibacterial, anti-infective.**Mechanism of Action of Fusidic acid*Fusidic acid is a bactericidal or bacteriostatic drug depending upon the concentration. It inhibits the transfer of aminoacid from aminoacyl sRNA to the protein. This will leads to inhibition of protein synthesis in the bacteria and prevent the growth of microbes.**Indications for Fusidic acid*Primary and secondary skin infections *1. Impetigo *2. Erythrasma *3. Folliculitis *4. Sycosis barbae *5. Hidradenitis
FUSIDERM 2% gel 15 GMFUSIDIC ACIDEVA PHARMA12.75About Fusidic acid*A bacteriostatic Steroid Antibiotic, Systemic antibacterial, anti-infective.**Mechanism of Action of Fusidic acid*Fusidic acid is a bactericidal or bacteriostatic drug depending upon the concentration. It inhibits the transfer of aminoacid from aminoacyl sRNA to the protein. This will leads to inhibition of protein synthesis in the bacteria and prevent the growth of microbes.**Indications for Fusidic acid*Primary and secondary skin infections *1. Impetigo *2. Erythrasma *3. Folliculitis *4. Sycosis barbae *5. Hidradenitis
FUSIDERM 2% oint. 15 GMSODIUM FUSIDATEEVA PHARMA12About Sodium Fusidate*Steroidal antibiotic (topical).*Mechanism of Action of Sodium Fusidate*Sodium fusidate is a bactericidal or bacteriostatic drug depending upon the concentration. It inhibits the transfer of aminoacid from aminoacyl sRNA to the protein. This will leads to inhibition of protein synthesis in the bacteria and prevent the growth of microbes.*Indications for Sodium Fusidate*Primary and secondary skin infections *1. Impetigo *2. Erythrasma *3. Folliculitis *4. Sycosis barbae *5. Hidradenitis
GAROPRIDE 50mg 30 F.C. TABS.ITOPRIDEEVA PHARMA30About Itopride*Dopamine(D2) antagonist, a prokinetic benzamide derivative, Motility stimulant.**Mechanism of Action of Itopride*Itopride has three way action. It inhibits the dopamine D2 receptor at the parasympathetic nerve ends.It increases the release of acetycholine and decreases the metabolism of acetylcholine by inhibiting the enzyme acetylcholinesterase (AChE). By maintaining higher acetylcholine levels, itopride increases the oesophageal and gastrointestinal peristalsis, increases the lower oesophageal sphincter pressure, stimulates gastric motility, accelerates gastric emptying and improves gastro-duodenal coordination. Itopride exerts anti-emetic actions because of its dopamine D2 receptor antagonistic action at CTZ. **Interactions for Itopride*Cisapride, atropine. *Typical Dosage for Itopride*Adult-Oral: 50 mg 3 times daily taken before each meal
GENUPHIL 250ml syrupCHONDROITIN -- GLUCOSAMINE -- METHYL SULPHONYL METHANEEVA PHARMAAnti-Rheumatic.Osteoarthritis.Anabolic Agents45About Chondroitin Sulphate*A sulfated glycosaminoglycan (mucopolysaccharides, Dietary supplement , anti-rheumatic and anti-inflammatory.*Mechanism of Action of Chondroitin Sulphate*Chondroitin sulfate is part of a large protein molecule (proteoglycan) that gives cartilage elasticity. *It stimulates cartilage cells to produce glucosaminoglycans and proteoglycans which are the building blocks of cartilage. This stops the progression of OA (osteoarthritis) and possibly reverses the process. It also has anti-inflammatory properties by its inhibition of proteolytic enzymes.
GENUPHIL 50 F.C. TAB.CHONDROITIN -- GLUCOSAMINE -- METHYL SULPHONYL METHANEEVA PHARMAAnti-Rheumatic.Osteoarthritis.Anabolic Agents99.5About Chondroitin Sulphate*A sulfated glycosaminoglycan (mucopolysaccharides, Dietary supplement , anti-rheumatic and anti-inflammatory.*Mechanism of Action of Chondroitin Sulphate*Chondroitin sulfate is part of a large protein molecule (proteoglycan) that gives cartilage elasticity. *It stimulates cartilage cells to produce glucosaminoglycans and proteoglycans which are the building blocks of cartilage. This stops the progression of OA (osteoarthritis) and possibly reverses the process. It also has anti-inflammatory properties by its inhibition of proteolytic enzymes.
GLEPTOMET 50/1000mg 10 f.c.tab.METFORMIN -- SITAGLIPTINEVA PHARMAAnti-Diabetic.Combined Secretagogues -- Sensitizers25It is an oral prescription medicine that, along with diet and exercise, helps lower blood sugar in adults with type 2 diabetes. These tablets contain 2 prescription medicines: sitagliptin and metformin. Your doctor will determine whether it is right for you.**It targets 3 key factors to lower blood sugar:** Helps your pancreas make more insulin* Helps your body more effectively use the insulin that it makes* Helps decrease excess sugar that your liver makes*** Helps control blood sugar throughout the day, including after meals* Is not likely to cause weight gain and low blood sugar (hypoglycemia) by itself**It can lower blood sugar more than metformin alone.**It is a powerful type 2 diabetes medicine that combines 2 prescription medicines, sitagliptin and metformin, and can lower blood sugar more than the most commonly prescribed medicine (metformin).
GLEPTOMET 50/500mg 10 f.c.tab.METFORMIN -- SITAGLIPTINEVA PHARMAAnti-Diabetic.Combined Secretagogues -- Sensitizers24It is an oral prescription medicine that, along with diet and exercise, helps lower blood sugar in adults with type 2 diabetes. These tablets contain 2 prescription medicines: sitagliptin and metformin. Your doctor will determine whether it is right for you.**It targets 3 key factors to lower blood sugar:** Helps your pancreas make more insulin* Helps your body more effectively use the insulin that it makes* Helps decrease excess sugar that your liver makes*** Helps control blood sugar throughout the day, including after meals* Is not likely to cause weight gain and low blood sugar (hypoglycemia) by itself**It can lower blood sugar more than metformin alone.**It is a powerful type 2 diabetes medicine that combines 2 prescription medicines, sitagliptin and metformin, and can lower blood sugar more than the most commonly prescribed medicine (metformin).
GLIMITOID 1mg 30 tabs.GLIMEPIRIDEEVA PHARMAAnti-Diabetic.Secretagogues.Sulfonylurea13.5Indications :* This medication is a sulfonylurea antidiabetic agent, prescribed for type 2 diabetes. It works by causing the pancreas to produce insulin**Dosage :*The recommended starting dose is 1-2 mg once daily,with food.Maximum: 2mg/day**Contraindications:* Contraindicated in patients with diabetic ketoacidosis, with or without coma, and hypersensitivity****
GLIMITOID 2mg 30 tabs.GLIMEPIRIDEEVA PHARMAAnti-Diabetic.Secretagogues.Sulfonylurea15Indications :* This medication is a sulfonylurea antidiabetic agent, prescribed for type 2 diabetes. It works by causing the pancreas to produce insulin**Dosage :*The recommended starting dose is 1-2 mg once daily,with food.Maximum: 2mg/day**Contraindications:* Contraindicated in patients with diabetic ketoacidosis, with or without coma, and hypersensitivity****
GLIMITOID 4mg 30 tabs.GLIMEPIRIDEEVA PHARMAAnti-Diabetic.Secretagogues.Sulfonylurea18Indications :* This medication is a sulfonylurea antidiabetic agent, prescribed for type 2 diabetes. It works by causing the pancreas to produce insulin**Dosage :*The recommended starting dose is 1-2 mg once daily,with food.Maximum: 2mg/day**Contraindications:* Contraindicated in patients with diabetic ketoacidosis, with or without coma, and hypersensitivity****
GLIPTUS 50 MG 30 TABS.VILDAGLIPTINEVA PHARMAAnti-Diabetic.Secretagogues.DPP-4 inhibitors104
GLIPTUS PLUS 50/1000mg 30 TABLETSMETFORMIN HYDROCHLORIDE -- VILDAGLIPTINEVA PHARMAAnti-Diabetic.Combined Secretagogues -- Sensitizers104About Metformin*Biguanide derivative, Oral anti-diabetic.*Mechanism of Action of Metformin*It is a biguanide which exerts antidiabetic action. The drug suppresses gluconeogenesis in liver and thus suppresses hepatic glucose output. It enhance insulin mediated glucose disposal in muscle and adipose tissue. It enhance GLUT1 (glucose transporter-1) transport from intracellular site to plasma membrane. It also interferes with respiratory chain in mitochondria and promotes peripheral glucose utilization by increasing anaerobic glycolysis. It inhibits intestinal absorption of glucose, other hexose sugars, amino acids and vitamin B12. It also improves lipid profile in type-2 diabetics.*Indications for Metformin*Non-insulin dependent diabetes mellitus (as adjunct to diet and exercise).*Typical Dosage for Metformin*Adults: Initial dose: 250mg twice or thrice daily with meals. Increase gradually at 2 week intervals, if required to a maximum of 3g daily. *Children: Not applicable.
GLIPTUS PLUS 50/850mg 30 TABLETSMETFORMIN HYDROCHLORIDE -- VILDAGLIPTINEVA PHARMAAnti-Diabetic.Combined Secretagogues -- Sensitizers104About Metformin*Biguanide derivative, Oral anti-diabetic.*Mechanism of Action of Metformin*It is a biguanide which exerts antidiabetic action. The drug suppresses gluconeogenesis in liver and thus suppresses hepatic glucose output. It enhance insulin mediated glucose disposal in muscle and adipose tissue. It enhance GLUT1 (glucose transporter-1) transport from intracellular site to plasma membrane. It also interferes with respiratory chain in mitochondria and promotes peripheral glucose utilization by increasing anaerobic glycolysis. It inhibits intestinal absorption of glucose, other hexose sugars, amino acids and vitamin B12. It also improves lipid profile in type-2 diabetics.*Indications for Metformin*Non-insulin dependent diabetes mellitus (as adjunct to diet and exercise).*Typical Dosage for Metformin*Adults: Initial dose: 250mg twice or thrice daily with meals. Increase gradually at 2 week intervals, if required to a maximum of 3g daily. *Children: Not applicable.
GLUCOSAMINE 30 Caps.GLUCOSAMINE -- VITAMIN CEVA PHARMA16.8About Glucosamine*Amino sugar,Monosaccharide derivative, Anti-inflammatory,Antiarthritic.*Mechanism of Action of Glucosamine*It stimulates cartilage cells to produce glucosaminoglycans and proteoglycans which are the building blocks of cartilage. This stops the progression of OA (osteoarthritis) and possibly reverses the process. It also has anti-inflammatory properties by its inhibition of proteolytic enzymes.*Indications for Glucosamine*1. Osteo arthritis. *2. Rheumatoid arthritis *Typical Dosage for Glucosamine*Oral- *Adult:1200mg /day
GLUCOSAMINE COMPOUND 30 F.C.tab.CHONDROITIN -- GLUCOSAMINE -- VITAMIN CEVA PHARMAAnti-Rheumatic.Osteoarthritis.Anabolic Agents36A combination formula providing critical nutrients to stimulate cells to help build joint cartilage.*Glucosamine. Glucosamine is a naturally occurring chemical found throughout the human body, including in the fluids surrounding joints. This formula contains 1,500 mg of glucosamine sulfate, the form of glucosamine used most often in research.* *Chondroitin. Chondroitin is another naturally occurring chemical, found in cartilage around joints in the body. Included are 1,200 mg of chondroitin sulfate, the most widely available and commonly used form of this nutrient.
HAIR TONE 40 Caps.BIOTIN -- CALCIUM PANTOTHENATE -- CYSTEINE -- KERATIN -- P-AMINOBENZOIC ACID -- SACCHAROMYCES -- VITAMIN(B1 -- B2 -- B6 -- E)EVA PHARMA38Mechanism of Action of Biotin*Biotin excerts it`s pharmacological action by influencing metabolic reactions. It acts as a coenzyme for carbohydrate, fat, and protein metabolism. It is required for cell growth and production of fatty acids. It is required for healthy maintenance of hair, skin, sweat glands, nerve tissue, and bone marrow. It also helps in the transfer of carbon dioxide and in the maintenance of a steady blood sugar level
HAIRGREW lotionD-PANTHENOL -- PILOCARPINE -- QUININEEVA PHARMA12
HEEL FORTE oint. 20 GMSALICYLIC ACID -- UREAEVA PHARMA7.5About Salicylic Acid*A beta hydroxy acid, Keratolytic, Topical Skin Product(Anti Acne).*Mechanism of Action of Salicylic Acid*It is a keratolytic agent. It encourages exfoliation of the skin and opening up of the plugged follicles, which helps re-establish the normal skin- cell replacement cycle. For milder acne, salicylic acid helps unclog pores to resolve and prevent lesions.
HEPAGUARD 40 tab.ACETYLCYSTEINE -- SILYMARINEVA PHARMALiver Support Supplement20
HIHAEM 100 MG 30 Cap.FERROUS GLYCINE SULPHATE COMPLEXEVA PHARMAAnemia.Iron Supplement45Indication*Iron-deficiency anemia, and various salts or complexes of iron are used as hematinics, including iron dextran, Iron , polysaccharide, i. sorbitex, and Iron sucrose. Hemochromatosis is an inherited disease in which too much iron builds up in your body. Breastfeeding Warnings,Pregnancy
KAPIFECTIN 250 mg 14 F.C.tab.CLARITHROMYCINEVA PHARMAAntibiotic.Macrolide24About Clarithromycin*It is a new macrolide antimicrobial drug.It is the most effective macrolide against Haemophilus influenzae, chlamydia trachomaitis and chlamydia pneumoniae.**Mechanism of Action of Clarithromycin*Clarithromycin is a member of macrolide antibiotic.It binds to the 50S sub unit of bacterial ribosome and inhibits translocation.ie:they interfere with the transfer of the newly formed peptide chain from the A site to the P site and fails to expose the A site .So that A site is unable to bind with the next aminoacyl tRNA complex. This leads to premature termination of amino acid chain and there by inhibits protein synthesis.**Indications for Clarithromycin*1.Tonsilitis *2.Pharyngitis *3.Pneumonia *4.Skin and soft tissue infections *5.Bronchitis *6.Otitis media *7.Prophylaxis of MAC *8.Leprosy *9.Acne *10.Nocardiosis
KAPIFECTIN 500 mg 14 F.C.tab.CLARITHROMYCINEVA PHARMAAntibiotic.Macrolide37About Clarithromycin*It is a new macrolide antimicrobial drug.It is the most effective macrolide against Haemophilus influenzae, chlamydia trachomaitis and chlamydia pneumoniae.**Mechanism of Action of Clarithromycin*Clarithromycin is a member of macrolide antibiotic.It binds to the 50S sub unit of bacterial ribosome and inhibits translocation.ie:they interfere with the transfer of the newly formed peptide chain from the A site to the P site and fails to expose the A site .So that A site is unable to bind with the next aminoacyl tRNA complex. This leads to premature termination of amino acid chain and there by inhibits protein synthesis.**Indications for Clarithromycin*1.Tonsilitis *2.Pharyngitis *3.Pneumonia *4.Skin and soft tissue infections *5.Bronchitis *6.Otitis media *7.Prophylaxis of MAC *8.Leprosy *9.Acne *10.Nocardiosis
KETALGIPAN 50mg 44*10 F.C. tab.KETOPROFENEVA PHARMANSAID.Propionic acid derivatives72About KetoprofenSNSAID, propionic acid derivative, Analgesic,antipyretic,antiinflammatory.SSMechanism of Action of KetoprofenSIt inhibits cyclo oxygenase enzymes both COX1 and COX2.These cyclooxygenase enzyme catalyses the synthesis of prostaglandins from arachidonic acid in the tissue. These inhibition produces its analgesic, antipyretic and anti inflammatory effects. It can also stabilize the lysosomal membrane. It is a Non Steroidal Anti Inflammatory Drug. It is a propionic acid derivative.SSIndications for KetoprofenS1. Rheumatoid arthritis S2. Osteo arthritis S3. Pain due to dysmenorrhea S4. Treatment for exacerbations of musculo skeletal, periarticular and soft tissue disorders S5. Migraine S6. Gout-Acute attack
LAMIDINE 100 mg 30 F.C. TAB.LAMIVUDINEEVA PHARMAAnti-Viral.Nucleoside90About Lamivudine*Nucleoside Reverse Transcriptase Inhibitor ,cytidine analogue, Antiretroviral.**Mechanism of Action of Lamivudine*Lamivudine is a deoxy cytidine nucleoside analogue. It undergoes phosphorylation in the presence of Kinase enzyme and form Lamivudine triphosphate. This Lamivudine triphosphate competitively inhibit HIV reverse transcriptase enzyme which is responsible for the conversion of viral RNA to pro viral DNA and is then added to host cell chromosome. Lamivudine triphosphate terminates elongation of pro viral DNA and results in inhibition of viral replication. Lamivudine triphosphate is also a potent inhibitor of HBV (hepatitis B virus)**Indications for Lamivudine*1.HIV infections *2.Treatment of chronic Hepatitis B**Interactions for Lamivudine*Trimethoprim, sulfamethoxazole: Results in an increase in AUC of Lamivudine and a decrease in renal clearance. *Zidovudine: Results in an increase in C max. of Zidovudine.
LAMIDINE 150mg 10f.c.tabLAMIVUDINEEVA PHARMAAnti-Viral.Nucleoside50About Lamivudine*Nucleoside Reverse Transcriptase Inhibitor ,cytidine analogue, Antiretroviral.**Mechanism of Action of Lamivudine*Lamivudine is a deoxy cytidine nucleoside analogue. It undergoes phosphorylation in the presence of Kinase enzyme and form Lamivudine triphosphate. This Lamivudine triphosphate competitively inhibit HIV reverse transcriptase enzyme which is responsible for the conversion of viral RNA to pro viral DNA and is then added to host cell chromosome. Lamivudine triphosphate terminates elongation of pro viral DNA and results in inhibition of viral replication. Lamivudine triphosphate is also a potent inhibitor of HBV (hepatitis B virus)**Indications for Lamivudine*1.HIV infections *2.Treatment of chronic Hepatitis B**Interactions for Lamivudine*Trimethoprim, sulfamethoxazole: Results in an increase in AUC of Lamivudine and a decrease in renal clearance. *Zidovudine: Results in an increase in C max. of Zidovudine.
LAMIZIDINE 10f.c.tab.LAMIVUDINE -- ZIDOVUDINEEVA PHARMA100About Lamivudine*Nucleoside Reverse Transcriptase Inhibitor ,cytidine analogue, Antiretroviral.*Mechanism of Action of Lamivudine*Lamivudine is a deoxy cytidine nucleoside analogue. It undergoes phosphorylation in the presence of Kinase enzyme and form Lamivudine triphosphate. This Lamivudine triphosphate competitively inhibit HIV reverse transcriptase enzyme which is responsible for the conversion of viral RNA to pro viral DNA and is then added to host cell chromosome. Lamivudine triphosphate terminates elongation of pro viral DNA and results in inhibition of viral replication. Lamivudine triphosphate is also a potent inhibitor of HBV (hepatitis B virus)
LAXEOL-PI 750mg/100 ml 15ml oral dropsSODIUM PICOSULPHATEEVA PHARMA5About Sodium Picosulphate*A locally acting Bowel preparation, A stimulant laxative.*Mechanism of Action of Sodium Picosulphate*Sodium picosulphate is a stimulant laxative. After oral administration it is activated by the bacteria present in the large intestine. It then stimulates nerve endings in the intestinal wall. Stimulation of nerves contracts the muscles in the intestine and rectum with more force (peristalsis) and the bowel can be emptied, and hence relieves constipation. Sodium picosulphate is also used to stimulate the emptying of the bowel before surgery, childbirth or medical investigation of the gut.*Indications for Sodium Picosulphate*1. Emptying the bowel prior to surgery, childbirth or radiological investigation of the gut. *2. Short term management of constipation. **Interactions for Sodium Picosulphate*Sodium picosulphate is broken down by bacteria in the large intestine so it is possible that patients taking broad spectrum antibiotics may experience some loss
LAXEOL-PI 750mg/100 ml 30ml oral dropsSODIUM PICOSULPHATEEVA PHARMALaxative6About Sodium Picosulphate*A locally acting Bowel preparation, A stimulant laxative.*Mechanism of Action of Sodium Picosulphate*Sodium picosulphate is a stimulant laxative. After oral administration it is activated by the bacteria present in the large intestine. It then stimulates nerve endings in the intestinal wall. Stimulation of nerves contracts the muscles in the intestine and rectum with more force (peristalsis) and the bowel can be emptied, and hence relieves constipation. Sodium picosulphate is also used to stimulate the emptying of the bowel before surgery, childbirth or medical investigation of the gut.*Indications for Sodium Picosulphate*1. Emptying the bowel prior to surgery, childbirth or radiological investigation of the gut. *2. Short term management of constipation. **Interactions for Sodium Picosulphate*Sodium picosulphate is broken down by bacteria in the large intestine so it is possible that patients taking broad spectrum antibiotics may experience some loss
LOCOPREX 0.05% TOPICAL CREAM 15 GMDESONIDEEVA PHARMA10Non flourinated corticosteroid for topical dermatological use.*It has anti-inflammatory, antipruritic and vasoconstrictive effects.
LOCOPREX 0.05% TOPICAL LOTION 60 GMDESONIDEEVA PHARMA31.2Non flourinated corticosteroid for topical dermatological use.*It has anti-inflammatory, antipruritic and vasoconstrictive effects.
LOCOPREX 0.05% TOPICAL OINTMENT 15 GMDESONIDEEVA PHARMA10Non flourinated corticosteroid for topical dermatological use.*It has anti-inflammatory, antipruritic and vasoconstrictive effects.
LORIN-D 10 CAPS.LORATADINE -- PSEUDOEPHEDRINEEVA PHARMAAnti-histamine.Anti-Allergy.Combined With Vasoconstrictor Agent5.25About Loratadine*Second Generation H1 Antagonist, Antihistamine.*Mechanism of Action of Loratadine*Loratadine blocks one type of receptor for histamine (the H1 receptor) and thus prevents activation (activation releasing other chemicals which produce the symptoms associated with allergy) of cells by histamine. Drug also has mast cell stabilizing property.*Interactions for Loratadine*Macrolide antibiotics, ketoconazole, cimetidine, ranitidine and theophylline: Caution should be exerted while co-administration of these drugs which are known to inhibit hepatic metabolism.*About Pseudoephedrine*Alpha/Beta Adrenergic Agonist, a phenethylamine derivative, A nasal decongestant.*Mechanism of Action of Pseudoephedrine*It is a nasal decongestant with alpha-2 agonistic action. It produces local vasoconstriction, reduces blood flow, and causes shrinkage of mucosa which provides relief of nasal congestion. It reduces oedema of the nasal mucosa, thus improving ventilation, drainage and nasa
MAGVITAL-B6 20 TABS.MAGNESIUM -- PYRIDOXINEEVA PHARMA11
MANOVIPERCAINE 10% spray 15 MLLIDOCAINEEVA PHARMAAnalgesic.Local Anesthetic12"Indication *For production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks.**Mechanism of action *Lidocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses thereby effecting local anesthetic action. Lidocaine alters signal conduction in neurons by blocking the fast voltage gated sodium (Na -- ) channels in the neuronal cell membrane that are responsible for signal propagation. With sufficient blockage the membrane of the postsynaptic neuron will not depolarize and will thus fail to transmit an action potential. This creates the anaesthetic effect by not merely preventing pain signals from propagating to the brain but by aborting their birth in the first place."
MAXISPECT 100mg/5ml oral susp. 100 MLCEFPODOXIMEEVA PHARMAAntibiotic.cephalosporin.third-generation40About Cefpodoxime*Third Generation Cephalosporin antibiotic, Oral antibiotic.**Mechanism of Action of Cefpodoxime*Cefpodoxime is a 3rd generation cephalosporin which exerts its bactericidal action mainly against gram positive organisms by inhibiting bacterial cell wall synthesis. Cefpodoxime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefpodoxime. *It is active against enterobacteriaceae, streptococci ,staphylococci aureus, & H. influenzae. **Indications for Cefpodoxime*1.Pneumonia, bronchitis &other respiratory tract infections *2.Sinusitis *3.Urinary tract &genital tract infections *4.Gonorrhea & rectal gonococcal infections *5.Skin infections *6.Otitismedia *7.Tonsillitis, Pharyngitis
METOGRAINE 20 tab.CAFFEINE -- ERGOTAMINE -- METOCLOPRAMIDE -- PARACETAMOL(ACETAMINOPHEN)EVA PHARMA8"About Caffeine*Xanthine alkaloid, Central stimulant and metabolic stimulant.*Mechanism of Action of Caffeine*Because caffeine is both water-soluble and lipid-soluble, it readily crosses the blood?brain barrier .Caffeine stimulates medullary, vagal, vasomotor, and respiratory centers, promoting bradycardia, vasoconstriction, and increased respiratory rate. Xanthines such as caffeine act as antagonists at adenosine-receptors within the plasma membrane of virtually every cell. As adenosine acts as an autocoid, inhibiting the release of neurotransmitters from presynaptic sites but augmenting the actions of norepinephrine or angiotensin, antagonism of adenosine receptors promotes neurotransmitter release. This explains the stimulatory effects of caffeine. Blockade of the adenosine A1 receptor in the heart leads to the accelerated, pronounced ""pounding"" of the heart upon caffeine intake."
MICAZOLE 2gm/100gm 20g oral gelMICONAZOLEEVA PHARMAantifungals.Imidazoles6.8About Miconazole*An imidazole derivative, Broad spectrum Antifungal.**Mechanism of Action of Miconazole*Miconazole is fungicidal or fungistatic depending on the drug concentrations. I t inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochromeP450 enzyme 14 alpha demethylase and impair ergosterol synthesis*Indications for Miconazole*1.Tinea versicolor *2.Vulvovaginal candidiasis *3.Tinea pedis *4.Tinea corporis *5.Tinea cruris *6.Otomycosis *7.Onychomycosis *8.Oral candidiasis *9.Intestinal candidiasis *10.Diaper dermatitis*
MICAZOLE 2gm/100gm 40g oral gelMICONAZOLEEVA PHARMAantifungals.Imidazoles10About Miconazole*An imidazole derivative, Broad spectrum Antifungal.**Mechanism of Action of Miconazole*Miconazole is fungicidal or fungistatic depending on the drug concentrations. I t inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochromeP450 enzyme 14 alpha demethylase and impair ergosterol synthesis*Indications for Miconazole*1.Tinea versicolor *2.Vulvovaginal candidiasis *3.Tinea pedis *4.Tinea corporis *5.Tinea cruris *6.Otomycosis *7.Onychomycosis *8.Oral candidiasis *9.Intestinal candidiasis *10.Diaper dermatitis*
MILGA 30 F.C. Tab.BENFOTIAMINE -- CYANOCOBALAMINE -- PYRIDOXINEEVA PHARMAvitamin31.5
MINOTENSOL 7.5 mg 20 F.C.tab.MOEXIPRILEVA PHARMAAnti-hypertensive.ACE32.4"Indication *For the treatment of hypertension.**Mechanism of action Moexipril is a prodrug for moexiprilat, which inhibits ACE in humans and animals. The mechanism through which moexiprilat lowers blood pressure is believed to be primarily inhibition of ACE activity. ACE is a peptidyl dipeptidase that catalyzes the conversion of the inactive decapeptide angiotensin I to the vasoconstrictor substance angiotensin II. Angiotensin II is a potent peripheral vasoconstrictor that also stimulates aldosterone secretion by the adrenal cortex and provides negative feedback on renin secretion. ACE is identical to kininase II, an enzyme that degrades bradykinin, an endothelium-dependent vasodilator. Moexiprilat is about 1000 times as potent as moexipril in inhibiting ACE and kininase II. Inhibition of ACE results in decreased angiotensin II formation, leading to decreased vasoconstriction, increased plasma renin activity, and decreased aldosterone secretion."
MOOV massage 40gram creamCAMPHOR -- CAMPHOR OIL -- MENTHOL -- METHYL SALICYLATE -- CAPSICIUM OLEORESINEVA PHARMAAnalgesic.Antirheumatic8.25About Capsaicin*A lipophilic capsaicinoid(methyl vanillyl nonenamide),substance P release inducer, A topical analgesic ,antineuralgic and antipruritic, rubefacient.*About Methyl salicylate*Salicylates, Rubefacient, counterirritant.*Mechanism of Action of Methyl salicylate*Methyl salicylate is a rubefacient. It produces reddening of the skin by dilatation of the blood vessel and gives a soothing feeling of warmth. It is also called as counterirritant because they produce their action by counter irritation. Irritation of the sensory nerve endings alters pain in the underlying muscle or joints that are served by the same nerves.*About Menthol*Terpenes and terpenoid, Antipruritic, decongestant, topical analgesic.*Mechanism of Action of Menthol*Menthol acts as a local anesthetic on the respiratory passageways and causing cough suppression. When Menthol is rubbed on the skin, it acts as a rubefacient and causes localized vasodilatation- which gives feelings of comfort and warmth. Wh
MOXIFLOX 0.5% EYE DROPS 5 MLMOXIFLOXACINEVA PHARMAAntibiotic.quinolone16.5About Moxifloxacin*A third generation synthetic fluoroquinolone Antibiotic, A broad spectrum antibiotic.*Mechanism of Action of Moxifloxacin*Moxifloxacin acts by inhibiting the enzyme DNA gyrase (Topoisomerase 2) and Topoisomerase 4.DNA gyrase helps in the formation of a highly condensed three dimensional structure of the DNA by its nicking and closing activity and also by introducing negative supercoil in to the DNA double helix. Moxifloxacin inhibits DNA gyrase which results in abnormal linkage between opened DNA and gyrase and negative supercoiling is impaired. This will inhibits transcription of DNA in to RNA and subsequent protein synthesis.**Indications for Moxifloxacin*1.Pneumonia *2.Bronchitis *3.Sinusitis *4.Skin infections *Interactions for Moxifloxacin*Antiarrhythmic agents (amiodarone, bretylium, disopyramide, procainamide, quinidine, sotalol): The risk of threatening cardiac arrhythmias may be increased.
MOXIFLOX 400mg 10 F.C. TABS.MOXIFLOXACINEVA PHARMAAntibiotic.quinolone148About Moxifloxacin*A third generation synthetic fluoroquinolone Antibiotic, A broad spectrum antibiotic.*Mechanism of Action of Moxifloxacin*Moxifloxacin acts by inhibiting the enzyme DNA gyrase (Topoisomerase 2) and Topoisomerase 4.DNA gyrase helps in the formation of a highly condensed three dimensional structure of the DNA by its nicking and closing activity and also by introducing negative supercoil in to the DNA double helix. Moxifloxacin inhibits DNA gyrase which results in abnormal linkage between opened DNA and gyrase and negative supercoiling is impaired. This will inhibits transcription of DNA in to RNA and subsequent protein synthesis.**Indications for Moxifloxacin*1.Pneumonia *2.Bronchitis *3.Sinusitis *4.Skin infections *Interactions for Moxifloxacin*Antiarrhythmic agents (amiodarone, bretylium, disopyramide, procainamide, quinidine, sotalol): The risk of threatening cardiac arrhythmias may be increased.
MOXIFLOX 400mg/250ML SOL. FOR INJ.MOXIFLOXACINEVA PHARMAAntibiotic.quinolone120.5About Moxifloxacin*A third generation synthetic fluoroquinolone Antibiotic, A broad spectrum antibiotic.*Mechanism of Action of Moxifloxacin*Moxifloxacin acts by inhibiting the enzyme DNA gyrase (Topoisomerase 2) and Topoisomerase 4.DNA gyrase helps in the formation of a highly condensed three dimensional structure of the DNA by its nicking and closing activity and also by introducing negative supercoil in to the DNA double helix. Moxifloxacin inhibits DNA gyrase which results in abnormal linkage between opened DNA and gyrase and negative supercoiling is impaired. This will inhibits transcription of DNA in to RNA and subsequent protein synthesis.**Indications for Moxifloxacin*1.Pneumonia *2.Bronchitis *3.Sinusitis *4.Skin infections *Interactions for Moxifloxacin*Antiarrhythmic agents (amiodarone, bretylium, disopyramide, procainamide, quinidine, sotalol): The risk of threatening cardiac arrhythmias may be increased.
MSM 30 TABSMETHYL SULPHONYL METHANEEVA PHARMA18For joint & muscles
MYOFEN 20 Caps.CHLORZOXAZONE -- IBUPROFENEVA PHARMA18"(Indications) : *This medication is a muscle relaxant, prescribed for muscle spasm and the resulting pain or discomfort. It is used in combination with physical therapy, analgesics (such as aspirin or acetaminophen), and rest. *About Chlorzoxazone*A benzoxazolone derivative, Centrally acting Muscle relaxant and mild sedative.*Mechanism of Action of Chlorzoxazone*This muscle relaxant works by blocking nerve impulses (or pain sensations) that are sent to your brain. It inhibits degranulation of mast cells, subsequently preventing the release of histamine and slow-reacting substance of anaphylaxis (SRS-A), mediators of type I allergic reactions. It may also reduce the release of inflammatory leukotrienes. Chlorzoxazone may act by inhibiting calcium influx. ***"
NICOTIPAN 1000 mg 20 extended release f.c. tabs.NICOTINIC ACIDEVA PHARMA54Mechanism of Action of Nicotinic Acid*Niacin refers to Nicotinic acid as well as Nicotinamide which exerts it`s action by influencing metabolic reactions. It is converted in to coenzymes Ncotinamide adenine dinucleotide (NAD) and its phosphate Ncotinamide adenine dinucleotide phosphate (NADP) involved in oxidation reduction reactions. These pyridine nucleotides act as hydrogen acceptors in the electron transport chain in tissue respiration, glycolysis, and fat synthesis. Nicotinic acid in high doses has vasodilator effects and also improves lipid profile- reduces serum cholesterol, raises HDL level, lowers VLDL, and LDL levels.*Indications for Nicotinic Acid*1. Pellagra *2. Niacin deficiency *3. Hartnup disease *4. Hyperlipidaemia (only nicotinic acid *5. Peripheral vascular diseases (only nicotinic acid)
NICOTIPAN 500 mg 20 extended release f.c. tabs.NICOTINIC ACIDEVA PHARMA42Mechanism of Action of Nicotinic Acid*Niacin refers to Nicotinic acid as well as Nicotinamide which exerts it`s action by influencing metabolic reactions. It is converted in to coenzymes Ncotinamide adenine dinucleotide (NAD) and its phosphate Ncotinamide adenine dinucleotide phosphate (NADP) involved in oxidation reduction reactions. These pyridine nucleotides act as hydrogen acceptors in the electron transport chain in tissue respiration, glycolysis, and fat synthesis. Nicotinic acid in high doses has vasodilator effects and also improves lipid profile- reduces serum cholesterol, raises HDL level, lowers VLDL, and LDL levels.*Indications for Nicotinic Acid*1. Pellagra *2. Niacin deficiency *3. Hartnup disease *4. Hyperlipidaemia (only nicotinic acid *5. Peripheral vascular diseases (only nicotinic acid)
NICOTIPAN 750 mg 20 extended release f.c. tabs.NICOTINIC ACIDEVA PHARMA48Mechanism of Action of Nicotinic Acid*Niacin refers to Nicotinic acid as well as Nicotinamide which exerts it`s action by influencing metabolic reactions. It is converted in to coenzymes Ncotinamide adenine dinucleotide (NAD) and its phosphate Ncotinamide adenine dinucleotide phosphate (NADP) involved in oxidation reduction reactions. These pyridine nucleotides act as hydrogen acceptors in the electron transport chain in tissue respiration, glycolysis, and fat synthesis. Nicotinic acid in high doses has vasodilator effects and also improves lipid profile- reduces serum cholesterol, raises HDL level, lowers VLDL, and LDL levels.*Indications for Nicotinic Acid*1. Pellagra *2. Niacin deficiency *3. Hartnup disease *4. Hyperlipidaemia (only nicotinic acid *5. Peripheral vascular diseases (only nicotinic acid)
NITORA 30 TABLETSMETHYL SULPHONYL METHANE -- ZINCEVA PHARMA22.5Special hair & skin formula
NOLICE 0.4gm/100 ml lotionPHENOTHRINEVA PHARMA7.15Phenothrin is a chemical that kills insects (an insecticide). It is a man-made (synthetic) chemical similar to the natural insecticides called pyrethrins. Phenothrin is one of a group of insecticides known as pyrethroids. It is also used to control scabies (a disease caused by mites that live on the skin).
NOLICE 0.4gm/100ml shampooPHENOTHRINEVA PHARMA9Phenothrin is a chemical that kills insects (an insecticide). It is a man-made (synthetic) chemical similar to the natural insecticides called pyrethrins. Phenothrin is one of a group of insecticides known as pyrethroids. It is also used to control scabies (a disease caused by mites that live on the skin).
NUCLEOBUVIR 400MG 28 TABLETSSOFOSBUVIREVA PHARMAAnti-Viral900INDICATIONS AND USAGE:*It is a hepatitis C virus (HCV) nucleotide analog NS5B polymerase inhibitor indicated for the treatment of chronic hepatitis C (CHC) infection as a component of a combination antiviral treatment regimen.**Efficacy has been established in subjects with HCV genotype 1, 2, 3 or 4 infection, including those with hepatocellular carcinoma meeting Milan criteria (awaiting liver transplantation) and those with HCV/HIV-1 co-infection.***DOSAGE AND ADMINISTRATION:** One 400 mg tablet taken once daily with or without food.** Should be used in combination with ribavirin or in combination with pegylated interferon and ribavirin for the treatment of CHC.*Recommended combination therapy:*HCV Mono-infected and HCV/HIV-1 Co-infected* Treatment Duration*Genotype 1 or 4 SOVALDI -- peg-interferon alfa -- ribavirin 12 weeks*Genotype 2 SO
OLANZA 5mg 30 F.C. Tab.OLANZAPINEEVA PHARMApsychiatric.Antipsychotics84.75"Indication *For the acute and maintenance treatment of schizophrenia and related psychotic disorders, as well as acute treatment of manic or mixed episodes of bipolar 1 disorder. Intramuscular olanzapine is indicated for the rapid control of agitated patients.*Mechanism of action Olanzapine s antipsychotic activity is likely due to a combination of antagonism at D2 receptors in the mesolimbic pathway and 5HT2A receptors in the frontal cortex. Antagonism at D2 receptors relieves positive symptoms while antagonism at 5HT2A receptors relieves negative symptoms of schizophrenia."
ORLY 120mg 30 Caps.ORLISTATEVA PHARMA100About Orlistat*Anti-obese drug. Saturated derivative of lipstatin.**Mechanism of Action of Orlistat*Its primary function is preventing the absorption of fats from the human diet, thereby reducing caloric intake.Orlistat works by inhibiting gastric and pancreatic lipases, the enzymes that break down triglycerides in the intestine. When lipase activity is blocked, triglycerides from the diet are not hydrolyzed into absorbable free fatty acids, and are excreted undigested instead.
OSSOFORTIN 0.25MG (10.000 I.U.) 30 TABS.ERGOCALCIFEROLEVA PHARMA30
OSSOFORTIN 1.25MG (50.000 I.U.) 30 TABS.ERGOCALCIFEROLEVA PHARMA54
OSTELOS gr.for oral 7sachet susp. in sachetsSTRONTIUM RANELATEEVA PHARMAOsteoporosis.Antiresorptives43About STRONTIUM RANEL*Bone metabolism modulator, Antiosteoporotic agent*Mechanism of Action of STRONTIUM RANEL*Strontium ranelate is an antiosteoporotic agent which both increases bone formation and reduces bone resorption. Strontium ranelate stimulates the calcium sensing receptors and leads to the differentiation of pre-osteoblast to osteoblast which increases the bone formation. Strontium ranelate also stimulates osteoblasts to secrete osteoprotegerin in inhibiting osteoclasts formed from pre-osteoclasts in relation to the RANKL system, which leads to the decrease of bone resorption*Indications for STRONTIUM RANEL*Postmenopausal Osteoporosis*Interactions for STRONTIUM RANEL*Food, milk and derivative products, and medicinal products containing calcium may reduce the bioavailability of strontium ranelate *May reduce the absorption of oral tetracycline and quinolone antibiotics
PANTHO EVA 5% emulgel 15 GMPANTHENOLEVA PHARMA5About Panthenol*Alcohol analog of pantothenic acid (vitamin B5), and is thus a provitamin of B5.*Mechanism of Action of Panthenol*Skin:It binds to the hair shaft readily and It coats the hair and seals its surface, lubricating the hair shaft and making strands appear shiny.Panthenol has good skin penetration. It improves hydration, reduces itching and inflammation of the skin and accelerates and improves healing of epidermal wounds. *Oral:If ingested, panthenol is metabolized to pantothenic acid.. Panthenol comes in two enantiomers, D and L. Only D-panthenol (dexpanthenol) is biologically active, however both forms have moisturizing properties. For cosmetic use, panthenol comes either in D form, or as a racemic mixture of D and L (DL-panthenol).
PANTHO EVA 7.5% topical sol. 50 MLPANTHENOLEVA PHARMAvitamin5.25About Panthenol*Alcohol analog of pantothenic acid (vitamin B5), and is thus a provitamin of B5.*Mechanism of Action of Panthenol*Skin:It binds to the hair shaft readily and It coats the hair and seals its surface, lubricating the hair shaft and making strands appear shiny.Panthenol has good skin penetration. It improves hydration, reduces itching and inflammation of the skin and accelerates and improves healing of epidermal wounds. *Oral:If ingested, panthenol is metabolized to pantothenic acid.. Panthenol comes in two enantiomers, D and L. Only D-panthenol (dexpanthenol) is biologically active, however both forms have moisturizing properties. For cosmetic use, panthenol comes either in D form, or as a racemic mixture of D and L (DL-panthenol).
PLAVEDAMOL 75mg 60 F.C. TABS.CLOPIDOGRELEVA PHARMAAntiplatlet.ADP receptor blocker36About Clopidogrel*Thienopyridine class, Platelet Aggregation Inhibitor, Antithrombic, Anti platelet agent.*Mechanism of Action of Clopidogrel*The drug exerts it`s antithrombotic action by interfering with platelet aggregation. It alters surface receptors in platelets and inhibits ADP induced platelet-fibrinogen and platelet-platelet binding and prevents platelet aggregation. It blocks G-protein coupled P2YAC type of inhibitory purinergic receptors which mediates adenylyl cyclase inhibition by ADP. It prolongs bleeding time.**Indications for Clopidogrel*1. To reduce atherosclerotic events *2. Thrombotic disorders *3. Prevention of stroke *4. Prophylaxis of myocardial infarction *5. Peripheral vascular diseases *6. Coronary artery diseases.
POWERECTA 10mg 4 DISINTEG. TABS.VARDENAFILEVA PHARMASexual tonic18About Vardenafil*Phosphodiesterase-5 Enzyme Inhibitor, In erectile dysfunction.
POWERECTA 2.5mg 1 F.C. TABS.VARDENAFILEVA PHARMASexual tonic2.25About Vardenafil*Phosphodiesterase-5 Enzyme Inhibitor, In erectile dysfunction.
POWERECTA 20mg 3 F.C. TABS.VARDENAFILEVA PHARMASexual tonic21.6About Vardenafil*Phosphodiesterase-5 Enzyme Inhibitor, In erectile dysfunction.
POWERECTA 5mg 1 F.C. TABS.VARDENAFILEVA PHARMASexual tonic3About Vardenafil*Phosphodiesterase-5 Enzyme Inhibitor, In erectile dysfunction.
PRAZOLAM 0.25 mg 30 tab.ALPRAZOLAMEVA PHARMApsychiatric.Anxiolytics-hypnotics15"Description *A triazolobenzodiazepine compound with antianxiety and sedative-hypnotic actions,**Indications*1.For the short-term management of anxiety, *2.Treatment of Panic disorder.**Contra-indications of Alprazolam*1.Hypersensitivity to Benzodiazepines *2.Acute angle closure glaucoma**Mechanism of Action of Alprazolam*Alprazolam mainly acts on Limbic system and ascending reticular formation in the CNS and binds to the BZD receptor. The binding will facilitates GABA mediated chloride channel opening and produce hyperpolarisation. This will produce an increase in the concentration of the inhibitory neurotransmitter GABA and increase in chloride ions and decreases firing rate of neuron. This in turn alters normal functions of the body."
PRAZOLAM 0.5mg 30 tab.ALPRAZOLAMEVA PHARMApsychiatric.Anxiolytics-hypnotics18.75"Description *A triazolobenzodiazepine compound with antianxiety and sedative-hypnotic actions,**Indications*1.For the short-term management of anxiety, *2.Treatment of Panic disorder.**Contra-indications of Alprazolam*1.Hypersensitivity to Benzodiazepines *2.Acute angle closure glaucoma**Mechanism of Action of Alprazolam*Alprazolam mainly acts on Limbic system and ascending reticular formation in the CNS and binds to the BZD receptor. The binding will facilitates GABA mediated chloride channel opening and produce hyperpolarisation. This will produce an increase in the concentration of the inhibitory neurotransmitter GABA and increase in chloride ions and decreases firing rate of neuron. This in turn alters normal functions of the body."
PREGAVALEX 150mg hard gelatin cap.PREGABALINEVA PHARMAAnti-epileptic.GABA analogs52About Pregabalin*A GABA agonist, Anticonvulsant.*Mechanism of Action of Pregabalin*Pregabalin is a GABA neurotransmitter analog. It produces its action by modulating calcium channels and also reduces the release of neurotransmitters such as Glutamate, Norepinephrine, Serotonin, Dopamine and Substance P.*Indications for Pregabalin*1.Epilepsy *2.Generalised anxiety disorder *3.Neuropathic pain *Typical Dosage for Pregabalin*150- 300mg / day in 2 divided doses
PREGAVALEX 25 mg 30 hard gelatin Caps.PREGABALINEVA PHARMAAnti-epileptic.GABA analogs69.75About Pregabalin*A GABA agonist, Anticonvulsant.*Mechanism of Action of Pregabalin*Pregabalin is a GABA neurotransmitter analog. It produces its action by modulating calcium channels and also reduces the release of neurotransmitters such as Glutamate, Norepinephrine, Serotonin, Dopamine and Substance P.*Indications for Pregabalin*1.Epilepsy *2.Generalised anxiety disorder *3.Neuropathic pain *Typical Dosage for Pregabalin*150- 300mg / day in 2 divided doses
PREGAVALEX 300mg hard gelatin 10Caps.PREGABALINEVA PHARMAAnti-epileptic.GABA analogs67About Pregabalin*A GABA agonist, Anticonvulsant.*Mechanism of Action of Pregabalin*Pregabalin is a GABA neurotransmitter analog. It produces its action by modulating calcium channels and also reduces the release of neurotransmitters such as Glutamate, Norepinephrine, Serotonin, Dopamine and Substance P.*Indications for Pregabalin*1.Epilepsy *2.Generalised anxiety disorder *3.Neuropathic pain *Typical Dosage for Pregabalin*150- 300mg / day in 2 divided doses
PREGAVALEX 50mg 30 hard gelatin cap.PREGABALINEVA PHARMAAnti-epileptic.GABA analogs69.75About Pregabalin*A GABA agonist, Anticonvulsant.*Mechanism of Action of Pregabalin*Pregabalin is a GABA neurotransmitter analog. It produces its action by modulating calcium channels and also reduces the release of neurotransmitters such as Glutamate, Norepinephrine, Serotonin, Dopamine and Substance P.*Indications for Pregabalin*1.Epilepsy *2.Generalised anxiety disorder *3.Neuropathic pain *Typical Dosage for Pregabalin*150- 300mg / day in 2 divided doses
PREGAVALEX 75 mg 30 hard gelatin Caps.PREGABALINEVA PHARMAAnti-epileptic.GABA analogs79.75About Pregabalin*A GABA agonist, Anticonvulsant.*Mechanism of Action of Pregabalin*Pregabalin is a GABA neurotransmitter analog. It produces its action by modulating calcium channels and also reduces the release of neurotransmitters such as Glutamate, Norepinephrine, Serotonin, Dopamine and Substance P.*Indications for Pregabalin*1.Epilepsy *2.Generalised anxiety disorder *3.Neuropathic pain *Typical Dosage for Pregabalin*150- 300mg / day in 2 divided doses
PREVAGLIP 5 MG 10 TABS.LINAGLIPTINEVA PHARMAAnti-Diabetic.Secretagogues.DPP-4 inhibitors51This is indicated in the treatment of type 2 diabetes mellitus to improve glycaemic control in adults:**as monotherapy** in patients inadequately controlled by diet and exercise alone and for whom metformin is inappropriate due to intolerance, or contraindicated due to renal impairment.**as combination therapy** in combination with metformin when diet and exercise plus metformin alone do not provide adequate glycaemic control.* in combination with a sulphonylurea and metformin when diet and exercise plus dual therapy with these medicinal products do not provide adequate glycaemic control.* in combination with insulin with or without metformin, when this regimen alone, with diet and exercise, does not provide adequate glycaemic control.
PREVAGLIP PLUS 2.5/1000MG 10 TABS.LINAGLIPTINEVA PHARMAAnti-Diabetic.Secretagogues.DPP-4 inhibitors33This is indicated in the treatment of type 2 diabetes mellitus to improve glycaemic control in adults:**as monotherapy** in patients inadequately controlled by diet and exercise alone and for whom metformin is inappropriate due to intolerance, or contraindicated due to renal impairment.**as combination therapy** in combination with metformin when diet and exercise plus metformin alone do not provide adequate glycaemic control.* in combination with a sulphonylurea and metformin when diet and exercise plus dual therapy with these medicinal products do not provide adequate glycaemic control.* in combination with insulin with or without metformin, when this regimen alone, with diet and exercise, does not provide adequate glycaemic control.
PREVAGLIP PLUS 2.5/500MG 10 TABS.LINAGLIPTINEVA PHARMAAnti-Diabetic.Secretagogues.DPP-4 inhibitors32This is indicated in the treatment of type 2 diabetes mellitus to improve glycaemic control in adults:**as monotherapy** in patients inadequately controlled by diet and exercise alone and for whom metformin is inappropriate due to intolerance, or contraindicated due to renal impairment.**as combination therapy** in combination with metformin when diet and exercise plus metformin alone do not provide adequate glycaemic control.* in combination with a sulphonylurea and metformin when diet and exercise plus dual therapy with these medicinal products do not provide adequate glycaemic control.* in combination with insulin with or without metformin, when this regimen alone, with diet and exercise, does not provide adequate glycaemic control.
PREVAGLIP PLUS 2.5/850MG 10 TABS.LINAGLIPTINEVA PHARMAAnti-Diabetic.Secretagogues.DPP-4 inhibitors33This is indicated in the treatment of type 2 diabetes mellitus to improve glycaemic control in adults:**as monotherapy** in patients inadequately controlled by diet and exercise alone and for whom metformin is inappropriate due to intolerance, or contraindicated due to renal impairment.**as combination therapy** in combination with metformin when diet and exercise plus metformin alone do not provide adequate glycaemic control.* in combination with a sulphonylurea and metformin when diet and exercise plus dual therapy with these medicinal products do not provide adequate glycaemic control.* in combination with insulin with or without metformin, when this regimen alone, with diet and exercise, does not provide adequate glycaemic control.
PROSTANORM 30 CAPSSAW PALMETTO BERRY POWDER -- PYGEUM RESINOUS WAXY -- STINGING NETTLE POWDER -- ZINC GLUCONATEEVA PHARMA85Improve prostate functions
PROSTETROL 10mg M.R. 30 tab.ALFUZOSINEVA PHARMAAntihypertensive.Selective Alpha 1 receptor blockers45"Description *Alfuzosin (INN, provided as the hydrochloride salt) is an alpha-adrenergic blocker used to treat benign prostatic hyperplasia**Indication :*For the reduction of urinary obstruction and relief of associated manifestations (eg. sensation of incomplete bladder emptying or straining, urgency, interrupted or weak stream) in patients with symptomatic beningn prostatic hyperplasia.**dosage:*The recommended dose is 2.5 mg 3 times/day. Max: 10 mg/day.**Mechanism of action:*Alfuzosin is a non-subtype specific alpha(1)-adrenergic blocking agent that exhibits selectivity for alpha(1)-adrenergic receptors in the lower urinary tract. Inhibition of these adrenoreceptors leads to the relaxation of smooth muscle in the bladder neck and prostate, resulting in the improvement in urine flow and a reduction in symptoms in benign prostate hyperplasia. Alfuzosin also inhibits the vasoconstrictor effect of circulating and locally released catecholamines (epinephrine and norepinephrine)"
PULMOCARE 125ml syrupCHLORPHENIRAMINE -- DEXTROMETHORPHAN -- GUAIFENESIN -- PSEUDOEPHEDRINEEVA PHARMAAnti-Cough.Antitussive and expectorant5.75"Description *A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma.*Indication For the treatment of rhinitis, urticaria, allergy, common cold, asthma and hay fever.*Pharmacodynamics In allergic reactions an allergen interacts with and cross-links surface IgE antibodies on mast cells and basophils. Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell-degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. Once released, histamine can react with local or widespread tissues through histamine receptors. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Chlorpheniramine, is a histamine H1 antagonist (or more correctly, an inverse histamine agonist) of the alkylamine class."
RAMIXOLE 0.25mg 30 TABS.PRAMIPEXOLEVA PHARMAParkinson s disease.Dopamine agonis33About Pramipexole*A nonergot Dopamine agonist, Antiparkinsonism.*Mechanism of Action of Pramipexole*Pramipexole is a non-ergot dopamine agonist. It stimulates Dopamine receptor in the striatum. It binds with high affinity to D3 receptors than D2 or D4 receptor subtypes. *It stimulates dopamine receptors in the striatum. It influences striatal neuronal firing rates via activation of dopamine receptors in the striatum and the substantia nigra. This produces the same effects as dopamine, and acts as a dopamine substitute. Pramipexole helps to restore the dopamine activity in the brain and reduce the symptoms of Parkinson`s disease. Pramipexole can be used in conjunction with Levodopa to treat Parkinson`s disease.*Indications for Pramipexole*Parkinson`s disease
RAMIXOLE 1 MG 10 tab.PRAMIPEXOLEVA PHARMAParkinson s disease.Dopamine agonis30About Pramipexole*A nonergot Dopamine agonist, Antiparkinsonism.*Mechanism of Action of Pramipexole*Pramipexole is a non-ergot dopamine agonist. It stimulates Dopamine receptor in the striatum. It binds with high affinity to D3 receptors than D2 or D4 receptor subtypes. *It stimulates dopamine receptors in the striatum. It influences striatal neuronal firing rates via activation of dopamine receptors in the striatum and the substantia nigra. This produces the same effects as dopamine, and acts as a dopamine substitute. Pramipexole helps to restore the dopamine activity in the brain and reduce the symptoms of Parkinson`s disease. Pramipexole can be used in conjunction with Levodopa to treat Parkinson`s disease.*Indications for Pramipexole*Parkinson`s disease
RAVEMANTINE 10mg f.c. tabs.MEMANTINEEVA PHARMA40About Memantine*N-Methyl-D-Aspartate Receptor Antagonist, dopamine D2 agonist, Antidementia agent,In Alzheimer`s disease.*Mechanism of Action of Memantine*Memantine in an uncompetitive (low to moderate affinity to) NMDA (N-methyl-D-aspartate) receptor antagonist. It regulates the activity of glutamate which is involved in information processing, storage and retrieval. Excess glutamate plays a role in neuronal cell death and it is common to all neurodegenerative diseases. *In Alzheimer`s disease excess release of glutamate occurs. Sustained elevation of glutamate over stimulates NMDA receptors and allows too much of calcium in to nerve cells and leads to cell degeneration and cell death. Memantine prevents these actions by inhibiting the binding of glutamate at NMDA receptor.
REGUPHOSE 800 mg 30 F.C. Tabs.SEVELAMEREVA PHARMA120About Sevelamer*Phosphate Binder, Management of hyperphosphataemia,urinary alkalinizer.*Mechanism of Action of Sevelamer*Sevelamer is a phosphate binder. It is used to reduce the level of phosphorus in chronic renal disease. It binds with phosphate in the gastrointestinal tract and decreases phosphate absorption. *These amines (Sevelamer) exist in a protonated form in the intestine and interact with phosphate molecules. It binds with phosphate in the dietary tract and decreases absorption. Sevelamer lowers the phosphate concentration in the serum. *Indications for Sevelamer*Hyperphosphataemia in chronic kidney disease*Typical Dosage for Sevelamer*Adult: 800 to 1600 mg / day in divided doses.
ROSAGEL 0.75gm/100gm gel 20 GMMETRONIDAZOLEEVA PHARMAAntiprotozoal.Nitroimidazole5.5About Metronidazole*A nitroimidazole antibiotic, Anti-infective, Antiprotozoal,amebicide.*Mechanism of Action of Metronidazole*Metronidazole is nitro imidazoles which have broad spectrum cidal activity against Protozoa and some anaerobic bacteria. Its selective toxicity to anaerobic microbes involves 1. Drug enters the cell by diffusion, 2. Nitro group of drug is reduced by redox proteins present only in anaerobic organisms to reactive nitro radical which exerts cytotoxic action by damaging DNA and other critical biomolecules. 3. DNA helix destabilization & strand breakage has been observed.*Indications for Metronidazole*1.Amoebiasis *2.Giardiasis *3.Trichomonas vaginitis *4.Pseudo membranous enterocolitis *5.Anaerobic bacterial infections after surgery, Brain abscess, & Endocarditis *6.Helicobacter pylori infections *7.Ulcerative gingivitis
SEPTOBAR 6 eff. sachet.HALFA BAR EXTRACT -- HEXAMINEEVA PHARMAUrinary.Analgesic.Antiseptic5
SIMVASTIMIBE 10/20mg 30 tabs.EZETIMIBE -- SIMVASTATINEVA PHARMAAntihyperlipidemic.Cholesterol Absorption Inhibitors.Combined with statin54About Ezetimibe*Cholesterol Absorption Inhibitor, 2-Azetidinone derivative, Hypolipidemic agent.*Mechanism of Action of Ezetimibe*It reduces the absorption of cholesterol from the intestine by localising at the brush border of the small intestine, where it inhibits the absorption of cholesterol from the diet. Specifically, it appears to bind to the Niemann-Pick C1-Like 1 (NPC1L1) protein on the gastrointestinal tract epithelium, a critical mediator of cholesterol absorption. This decreased cholesterol absorption leads to an increase in LDL-cholesterol uptake into cells, thus decreasing levels in the blood plasma.*Indications for Ezetimibe*1. Adjunct to dietary measures and statin in primary and homozygous familial hypercholesterolaemia *2. Adjunct to dietary measures in homozygous familial sitosterolaemia *Interactions for Ezetimibe*Cyclosporin: Plasma concentraction of ezetimibe increased. Lipid-regulating drugs: Avoid concomitant use with fibrates.
SIMVASTIMIBE 10/40mg 30 tabs.EZETIMIBE -- SIMVASTATINEVA PHARMAAntihyperlipidemic.Cholesterol Absorption Inhibitors.Combined with statin61.5About Ezetimibe*Cholesterol Absorption Inhibitor, 2-Azetidinone derivative, Hypolipidemic agent.*Mechanism of Action of Ezetimibe*It reduces the absorption of cholesterol from the intestine by localising at the brush border of the small intestine, where it inhibits the absorption of cholesterol from the diet. Specifically, it appears to bind to the Niemann-Pick C1-Like 1 (NPC1L1) protein on the gastrointestinal tract epithelium, a critical mediator of cholesterol absorption. This decreased cholesterol absorption leads to an increase in LDL-cholesterol uptake into cells, thus decreasing levels in the blood plasma.*Indications for Ezetimibe*1. Adjunct to dietary measures and statin in primary and homozygous familial hypercholesterolaemia *2. Adjunct to dietary measures in homozygous familial sitosterolaemia *Interactions for Ezetimibe*Cyclosporin: Plasma concentraction of ezetimibe increased. Lipid-regulating drugs: Avoid concomitant use with fibrates.
SIMVASTIMIBE 10/80mg tabs.EZETIMIBE -- SIMVASTATINEVA PHARMAAntihyperlipidemic.Cholesterol Absorption Inhibitors.Combined with statin42About Ezetimibe*Cholesterol Absorption Inhibitor, 2-Azetidinone derivative, Hypolipidemic agent.*Mechanism of Action of Ezetimibe*It reduces the absorption of cholesterol from the intestine by localising at the brush border of the small intestine, where it inhibits the absorption of cholesterol from the diet. Specifically, it appears to bind to the Niemann-Pick C1-Like 1 (NPC1L1) protein on the gastrointestinal tract epithelium, a critical mediator of cholesterol absorption. This decreased cholesterol absorption leads to an increase in LDL-cholesterol uptake into cells, thus decreasing levels in the blood plasma.*Indications for Ezetimibe*1. Adjunct to dietary measures and statin in primary and homozygous familial hypercholesterolaemia *2. Adjunct to dietary measures in homozygous familial sitosterolaemia *Interactions for Ezetimibe*Cyclosporin: Plasma concentraction of ezetimibe increased. Lipid-regulating drugs: Avoid concomitant use with fibrates.
SINLERG 20 TABLETSCHLORPHENIRAMINE -- IBUPROFEN -- PSEUDOEPHEDRINEEVA PHARMA21For cold & flu
SLIMMER SWEETENER 100 SACHETSSUCRALOSEEVA PHARMA521 Sachet = 2 teaspoonful of normal sugar
SLIMMER SWEETENER 300 SACHETSSUCRALOSEEVA PHARMA1271 Sachet = 2 teaspoonful of normal sugar
SLIMMER SWEETENER 50 SACHETSSUCRALOSEEVA PHARMA28.51 Sachet = 2 teaspoonful of normal sugar
SOLITRACT 10mg 30 F.C. Tab.SOLIFENACIN SUCCINATEEVA PHARMAUrinary incontinence.Antispasmodics.Muscarinic Antagonists113.5"Indication For the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency.*Mechanism of action Solifenacin is a competitive muscarinic acetylcholine receptor antagonist. The binding of acetylcholine to these receptors, particularly the M3 receptor subtype, plays a critical role in the contraction of smooth muscle. By preventing the binding of acetylcholine to these receptors, solifenacin reduces smooth muscle tone in the bladder, allowing the bladder to retain larger volumes of urine and reducing the number of incontinence episodes."
SOLITRACT 5mg 30 F.C. Tab.SOLIFENACIN SUCCINATEEVA PHARMAUrinary incontinence.Antispasmodics.Muscarinic Antagonists86.5"Indication For the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency.*Mechanism of action Solifenacin is a competitive muscarinic acetylcholine receptor antagonist. The binding of acetylcholine to these receptors, particularly the M3 receptor subtype, plays a critical role in the contraction of smooth muscle. By preventing the binding of acetylcholine to these receptors, solifenacin reduces smooth muscle tone in the bladder, allowing the bladder to retain larger volumes of urine and reducing the number of incontinence episodes."
SOPROL 10mg 30 F.C.tabBISOPROLOL FUMARATEEVA PHARMAAnti-hypertensive.Beta blocker.Selective B127About Bisoprolol*Beta1-selective adrenergic blocker, Antihypertensive.**Mechanism of Action of Bisoprolol*Bisoprolol is a cardio selective beta-1 adrenergic antagonist.It has negative chronotropic and negative inotropic effects on heart. It decreases oxygen consumption- cardiac work and aortic pressure. It decreases central sympathetic out flow and also decreases nor adrenaline and renin releases. The drug decreases BP in hypertensive individuals. **Indications for Bisoprolol*1.Hypertension *2.Coronary artery diseases **Contra-indications of Bisoprolol*1.Hypersensitivity to the drug *2.Second or third degree heart block *3.Congestive heart failure *4.Cardiogenic shock *5.Sinus Bradycardia *6.Chronic obstructive pulmonary diseases *7.Bronchial asthma *9.Peripheral arteriolar disorders *10.Renal impairment.
SOPROL 5mg 20 F.C.tab.BISOPROLOL FUMARATEEVA PHARMAAnti-hypertensive.Beta blocker.Selective B114About Bisoprolol*Beta1-selective adrenergic blocker, Antihypertensive.**Mechanism of Action of Bisoprolol*Bisoprolol is a cardio selective beta-1 adrenergic antagonist.It has negative chronotropic and negative inotropic effects on heart. It decreases oxygen consumption- cardiac work and aortic pressure. It decreases central sympathetic out flow and also decreases nor adrenaline and renin releases. The drug decreases BP in hypertensive individuals. **Indications for Bisoprolol*1.Hypertension *2.Coronary artery diseases **Contra-indications of Bisoprolol*1.Hypersensitivity to the drug *2.Second or third degree heart block *3.Congestive heart failure *4.Cardiogenic shock *5.Sinus Bradycardia *6.Chronic obstructive pulmonary diseases *7.Bronchial asthma *9.Peripheral arteriolar disorders *10.Renal impairment.
SOPROL PLUS 5/12.5mg 20 F.C.tabBISOPROLOL FUMARATE -- HYDROCHLOROTHIAZIDEEVA PHARMAAnti-hypertensive.Combined Beta blocker with Diuretic14Indications for Bisoprolol -- Hydrochlorothiazide*It is the combination of beta blocker Bisoprolol and diuretic Hydrochlorothiazide. *Hypertention **Typical Dosage for Bisoprolol -- Hydrochlorothiazide*1 tablet / day**Pregnancy Related Information*Contraindicated- since Hydrochlorothiazide is contraindicated in pregnancy, the combination generic cannot be used in pregnancy*Breast Feeding Related Information*Contraindicated- since Hydrochlorothiazide is contraindicated in lactation, the combination generic cannot be used in breast feeding.*
STADIVIR 40mg hard gelatin 10Caps.STAVUDINEEVA PHARMAAnti-Viral.Nucleoside50About Stavudine*Nucleoside Reverse Transcriptase Inhibitor, Antiretroviral Agent.*Mechanism of Action of Stavudine*Stavudine is a Thymidine nucleoside analogue. It undergoes phosphorylation in the presence of Kinase enzyme and form Stavudine triphosphate. This Stavudine triphosphate competitively inhibit HIV reverse transcriptase enzyme which is responsible for the conversion of viral RNA to pro viral DNA and is then added to host cell chromosome. Stavudine triphosphate terminates elongation of pro viral DNA and results in inhibition of viral replication.
STOPADOL EXTRA 20 tab.CAFFEINE -- PARACETAMOL(ACETAMINOPHEN)EVA PHARMA7mechanism:*It is thought paracetamol reduces fever by affecting an area of the brain that regulates our body temperature (the hypothalamic heat-regulating center).*Paracetamol is about as effective as aspirin or ibuprofen at relieving mild to moderate pain and fever, but unlike aspirin and ibuprofen it has no anti-inflammatory effect.*Caffeine is a mild stimulant that helps reduce fatigue. Caffeine is also thought to enhance the painkilling effect of paracetamol.**What is it used for?*Mild to moderate pain, such as headache, migraine, toothache, sore throat, muscular and rheumatic pain, nerve pain (neuralgia), backache (lumbago) and period pain.*Relieving aches, pains, sore throat and fever associated with colds and flu.***
STOPAIN 10 tab.CAFFEINE -- PARACETAMOL(ACETAMINOPHEN) -- PROPYPHENAZONEEVA PHARMA2.55"About Caffeine*Xanthine alkaloid, Central stimulant and metabolic stimulant.*Mechanism of Action of Caffeine*Because caffeine is both water-soluble and lipid-soluble, it readily crosses the blood?brain barrier .Caffeine stimulates medullary, vagal, vasomotor, and respiratory centers, promoting bradycardia, vasoconstriction, and increased respiratory rate. Xanthines such as caffeine act as antagonists at adenosine-receptors within the plasma membrane of virtually every cell. As adenosine acts as an autocoid, inhibiting the release of neurotransmitters from presynaptic sites but augmenting the actions of norepinephrine or angiotensin, antagonism of adenosine receptors promotes neurotransmitter release. This explains the stimulatory effects of caffeine. Blockade of the adenosine A1 receptor in the heart leads to the accelerated, pronounced ""pounding"" of the heart upon caffeine intake."
SUDOPHINE 10mg/5ml 120ml syrupPSEUDOEPHEDRINEEVA PHARMA5About Pseudoephedrine*Alpha/Beta Adrenergic Agonist, a phenethylamine derivative, A nasal decongestant.*Mechanism of Action of Pseudoephedrine*It is a nasal decongestant with alpha-2 agonistic action. It produces local vasoconstriction, reduces blood flow, and causes shrinkage of mucosa which provides relief of nasal congestion. It reduces oedema of the nasal mucosa, thus improving ventilation, drainage and nasal stuffiness.*Indications for Pseudoephedrine*1. Nasal and Eustachian tube congestion *2.Upper respiratory tract congestion *3.Adjunctive therapy in symptomatic relief of common cold, allergic rhinitis, blocked Eustachian tube, and upper respiratory tract infections
TECAVIR 0.05mg/ml oral soln.ENTECAVIREVA PHARMAAnti-Viral.Nucleoside450About Entecavir*Nucleoside analog, reverse transcriptase inhibitor, oral antiviral drug used in the treatment of hepatitis B infection.**Mechanism of Action of Entecavir*By competing with the natural substrate deoxyguanosine triphosphate, entecavir functionally inhibits all three activities of the HBV polymerase (reverse transcriptase, rt): (1) base priming, (2) reverse transcription of the negative strand from the pregenomic messenger RNA, and (3) synthesis of the positive strand of HBV DNA. Upon activation by kinases, the drug can be incorporated into the DNA which has the ultimate effect of inhibiting the HBV polymerase activity.**Indications for Entecavir*For the treatment of chronic hepatitis B virus infection in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease.
TECAVIR 0.5mg 30 f.c. tab.ENTECAVIREVA PHARMAAnti-Viral.Nucleoside900About Entecavir*Nucleoside analog, reverse transcriptase inhibitor, oral antiviral drug used in the treatment of hepatitis B infection.**Mechanism of Action of Entecavir*By competing with the natural substrate deoxyguanosine triphosphate, entecavir functionally inhibits all three activities of the HBV polymerase (reverse transcriptase, rt): (1) base priming, (2) reverse transcription of the negative strand from the pregenomic messenger RNA, and (3) synthesis of the positive strand of HBV DNA. Upon activation by kinases, the drug can be incorporated into the DNA which has the ultimate effect of inhibiting the HBV polymerase activity.**Indications for Entecavir*For the treatment of chronic hepatitis B virus infection in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease.
TECAVIR 1mg 20 f.c.tab.ENTECAVIREVA PHARMAAnti-Viral.Nucleoside900About Entecavir*Nucleoside analog, reverse transcriptase inhibitor, oral antiviral drug used in the treatment of hepatitis B infection.**Mechanism of Action of Entecavir*By competing with the natural substrate deoxyguanosine triphosphate, entecavir functionally inhibits all three activities of the HBV polymerase (reverse transcriptase, rt): (1) base priming, (2) reverse transcription of the negative strand from the pregenomic messenger RNA, and (3) synthesis of the positive strand of HBV DNA. Upon activation by kinases, the drug can be incorporated into the DNA which has the ultimate effect of inhibiting the HBV polymerase activity.**Indications for Entecavir*For the treatment of chronic hepatitis B virus infection in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease.
TENAVIRON 300 MG 30 TABLETSTENOFOVIR DISOPROXIL FUMARATEEVA PHARMAAnti-Viral.Nucleoside360It s indicated for treatment of chronic hepatitis B in adults and pediatrics 12 years of age and older.*Dose: Once daily for certain period of time determined by the physician.*
TENDRATINE 25mg/5ml 100ml syrupDESLORATADINEEVA PHARMAAnti-histamine.Anti-Allergy9About Desloratadine*Second Generation long-acting tricyclic H1 Antagonist, Antihistamine.**Mechanism of Action of Desloratadine*This second generation antihistamine has a selective peripheral H1-antagonist action.Desloratadine competes with free histamine for binding at H1-receptors in the GI tract, uterus, large blood vessels, and bronchial smooth muscle. This inhibit the action of histamine, which subsequently leads to temporary relief of the negative symptoms brought by histamine**Indications for Desloratadine*1. Hay fever *2. Watery eyes *3. Runny nose *4. Itching eyes *5. Sneezing *6. Hives *7. Decongestant **Typical Dosage for Desloratadine**Adult (general dose)- 5mg/day *Children (-12yrs)-Same as adult
THIOTACID 300mg 30 tab.THIOCTIC ACIDEVA PHARMAvitamin67.5"Indication *For nutritional supplementation, also for treating dietary shortage or imbalance.*Mechanism of action Lipoic Acid is generally involved in oxidative decarboxylations of keto acids and is presented as a growth factor for some organisms. Lipoic acid exists as two enantiomers, the R-enantiomer and the S-enantiomer. Normally only the R-enantiomer of an amino acid is biologically active, but for lipoic acid the S-enantiomer assists in the reduction of the R-enantiomer when a racemic mixture is given. Some recent studies have suggested that the S-enantiomer in fact has an inhibiting effect on the R-enantiomer, reducing its biological activity substantially and actually adding to oxidative stress rather than reducing it. Furthermore, the S-enantiomer has been found to reduce the expression of GLUT-4s in cells, responsible for glucose uptake, and hence reduce insulin sensitivity."
THIOTACID 300mg 5 I.V. AMP 10 MLTHIOCTIC ACIDEVA PHARMAvitamin46.5"Indication *For nutritional supplementation, also for treating dietary shortage or imbalance.*Mechanism of action Lipoic Acid is generally involved in oxidative decarboxylations of keto acids and is presented as a growth factor for some organisms. Lipoic acid exists as two enantiomers, the R-enantiomer and the S-enantiomer. Normally only the R-enantiomer of an amino acid is biologically active, but for lipoic acid the S-enantiomer assists in the reduction of the R-enantiomer when a racemic mixture is given. Some recent studies have suggested that the S-enantiomer in fact has an inhibiting effect on the R-enantiomer, reducing its biological activity substantially and actually adding to oxidative stress rather than reducing it. Furthermore, the S-enantiomer has been found to reduce the expression of GLUT-4s in cells, responsible for glucose uptake, and hence reduce insulin sensitivity."
THIOTACID 600mg 20 F.C.tab.THIOCTIC ACIDEVA PHARMA67.5"Indication *For nutritional supplementation, also for treating dietary shortage or imbalance.*Mechanism of action Lipoic Acid is generally involved in oxidative decarboxylations of keto acids and is presented as a growth factor for some organisms. Lipoic acid exists as two enantiomers, the R-enantiomer and the S-enantiomer. Normally only the R-enantiomer of an amino acid is biologically active, but for lipoic acid the S-enantiomer assists in the reduction of the R-enantiomer when a racemic mixture is given. Some recent studies have suggested that the S-enantiomer in fact has an inhibiting effect on the R-enantiomer, reducing its biological activity substantially and actually adding to oxidative stress rather than reducing it. Furthermore, the S-enantiomer has been found to reduce the expression of GLUT-4s in cells, responsible for glucose uptake, and hence reduce insulin sensitivity."
THIOTACID COMPOUND 300 MG 30 Caps.THIOCTIC ACID -- VITAMIN B1 -- VITAMIN B12EVA PHARMA67.5
THIOTACID COMPOUND 600 MG 20 F.C.capletsTHIOCTIC ACID -- VITAMIN B1 -- VITAMIN B12EVA PHARMA67.5
TINOX 1% cream 15 GMOXICONAZOLEEVA PHARMAantifungals.Imidazoles10About Oxiconazole*Imidazole derivative, Antifungal.**Mechanism of Action of Oxiconazole*Oxiconazole is fungicidal or fungistatic depending on concentrations. It inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochromeP450 enzyme 14 alpha demethylase and impair ergosterol synthesis. This will alter cellular membrane integrity of fungus.*Indications for Oxiconazole*1. Tinea corporis (ring worm of the body) *2. Tinea cruris (ring worm of the groin and jock itch) *3. Pityriasis versicolor *4. Tinea pedis
TINOX 1% LOTION 50 MLOXICONAZOLEEVA PHARMAantifungals.Imidazoles24About Oxiconazole*Imidazole derivative, Antifungal.**Mechanism of Action of Oxiconazole*Oxiconazole is fungicidal or fungistatic depending on concentrations. It inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochromeP450 enzyme 14 alpha demethylase and impair ergosterol synthesis. This will alter cellular membrane integrity of fungus.*Indications for Oxiconazole*1. Tinea corporis (ring worm of the body) *2. Tinea cruris (ring worm of the groin and jock itch) *3. Pityriasis versicolor *4. Tinea pedis
TOPINOID 0.05% top. Gel 15 GMTAZAROTENEEVA PHARMA11"Indication Used to treat psoriasis, acne and sun damaged skin (photodamage).*Mechanism of action Although the exact mechanism of tazarotene action is not known, studies have shown that the active form of the drug (tazarotenic acid) binds to all three members of the retinoic acid receptor (RAR) family: RARa, RARb, and RARg, but shows relative selectivity for RARb, and RARg and may modify gene expression. It also has affinity for RXR receptors."
TREMODECT 1 mg 30 F.C.tabs.ROPINIROLEEVA PHARMAParkinson s disease.Dopamine agonist31.5About Ropinirole*A non-ergoline Dopamine Agonist, Anti-Parkinson`s Agent.*Mechanism of Action of Ropinirole*Ropinirole is a non-ergoline Dopamine agonist. The antiparkinsonian activity is due to stimulatory effect on post synaptic Dopamine receptors (D2) within the caudate- putamen. It has affinity for other dopamine receptors such as D3 &D4. Ropinirole also has moderate invitro affinity for opioid receptors. Ropinirole and its metabolite has very little affinity for D1, 5HT1, 5HT2,Benzodiazepines, GABA, muscarinic, alpha and beta adreno receptors. *Indications for Ropinirole*1. Parkinson`s disease - idiopathic Parkinson`s disease.*Interactions for Ropinirole*Oestrogens decrease the oral clearance of ropinirole thereby increasing its plasma levels. *Cimetidine, ciprofloxacin, Diltiazem and Mexiletene increase its levels by altering the clearance. *Phenothiazines and butyrophenones decrease its effectiveness.
TREMODECT 4 mg 30 F.C.tabs.ROPINIROLEEVA PHARMAParkinson s disease.Dopamine agonist52.5About Ropinirole*A non-ergoline Dopamine Agonist, Anti-Parkinson`s Agent.*Mechanism of Action of Ropinirole*Ropinirole is a non-ergoline Dopamine agonist. The antiparkinsonian activity is due to stimulatory effect on post synaptic Dopamine receptors (D2) within the caudate- putamen. It has affinity for other dopamine receptors such as D3 &D4. Ropinirole also has moderate invitro affinity for opioid receptors. Ropinirole and its metabolite has very little affinity for D1, 5HT1, 5HT2,Benzodiazepines, GABA, muscarinic, alpha and beta adreno receptors. *Indications for Ropinirole*1. Parkinson`s disease - idiopathic Parkinson`s disease.*Interactions for Ropinirole*Oestrogens decrease the oral clearance of ropinirole thereby increasing its plasma levels. *Cimetidine, ciprofloxacin, Diltiazem and Mexiletene increase its levels by altering the clearance. *Phenothiazines and butyrophenones decrease its effectiveness.
TREMOGINE 10 mg 10 tab.SELEGILINE CHLORIDEEVA PHARMAParkinson s disease.MAO-B inhibitor13About Selegiline*A selective irreversible MAO-B inhibitor, Phenethylamine derivative, Antiparkinsonian agent, Antidepressant.*Mechanism of Action of Selegiline*Selegiline is a Monoamine oxidase enzyme inhibitor. It selectively blocks MAO-B than MAO-A at recommended dose. Selegiline inhibits the reuptake of Dopamine in to the presynaptic nerve terminal and also blocks presynaptic Dopamine receptor. This will produce Dopaminergic activity. Metabolites of Selegiline (Amphetamine and Methamphetamine) interferes the reuptake and enhances the release of neurotransmitters such as Noradrenaline, Dopamine and Serotonin and produces antidepressant effect. *Antiparkinsonian action: MAO-B (Monoamine oxidase enzyme-B) in the CNS is responsible for the metabolism of Dopamine to DOPAC (3, 4 Dihydroxy-phenyl acetic acid). Selegiline binds to MAO-B and inhibits the Dopamine degradation. Selegiline produces an increase in the concentration of Dopamine in the CNS
TRITOSPOT cream 15 GMEUSELX OILY -- HYDROCORTISONE ACETATE -- HYDROQUINONE -- TRETINOINEVA PHARMA12About Hydroquinone*Benzenediol derivative, Depigmenting Agent.*Mechanism of Action of Hydroquinone*Hydroquinone decreases the formation of melanin in the skin. It inhibits tyrosinase and other melanin forming enzymes and thus decreases the formation and increases the degradation of melanosomes.
TRITOSPOT cream 30 GMEUSELX OILY -- HYDROCORTISONE ACETATE -- HYDROQUINONE -- TRETINOINEVA PHARMA16.5About Hydroquinone*Benzenediol derivative, Depigmenting Agent.*Mechanism of Action of Hydroquinone*Hydroquinone decreases the formation of melanin in the skin. It inhibits tyrosinase and other melanin forming enzymes and thus decreases the formation and increases the degradation of melanosomes.
TROMACURE topical gel 40 GMAESCIN -- DIETHYLAMINE SALICYLATEEVA PHARMANSAID.Antirehumatic.Salicylates8.5Indications :SS- In cases of contusions, crush injuries, sprains .bruises, haematoma and tenosynovitis.S- Painful conditions of the vertebral column (disc lesions, neck pain, lumbago, sciatica).S- In superficial thrombophlebitis ,varicose veins ,for care ofS- the veins after injections or infusions.SSContraindications :SSHypersensitivity to any of the drug components. Reparil-Gel N should not be applied to eyes, broken skin, mucous membranes or skin areas exposed to radiotherapy.
TROSPAMEXIN 20mg 20 F.C. TABS.TROSPIUM CHLORIDEEVA PHARMAUrinary antispasmodic.42Trospium chloride is used for the treatment of overactive bladder with symptoms of urge incontinence and frequent urination.**It shouldn t be used with people who retain urine, who have severe digestive conditions, myasthenia gravis, narrow-angle glaucoma, or tachyarrhythmia.
TUSSAPIN 20mg 10 lozengeDROPRIPIZINEEVA PHARMA4The antitussive efficacy and tolerability of dropropizine and of its enantiomer levodropropizine were evaluated in children with non-productive cough- 258 were evaluable for tolerability and 254 for efficacy. Patients randomly received either 1 mg/kg dropropizine or 2 mg/kg levodropropizine orally, three times daily for 3 days.
ULCFREE 150mg 20 Caps.NIZATIDINEEVA PHARMAPeptic Ulcer.Anti-Histamine.H2 Antagonist21"Indication *For the treatment of acid-reflux disorders (GERD), peptic ulcer disease, active benign gastric ulcer, and active duodenal ulcer.*Pharmacodynamics *Nizatidine is a competitive, reversible inhibitor of histamine at the histamine H2-receptors, particularly those in the gastric parietal cells. By inhibiting the action of histamine on stomach cells, nizatidine reduces stomach acid production. Nizatidine had no demonstrable antiandrogenic action. Full-dose therapy for the problems treated by nizatidine lasts no longer than 8 weeks. It has been demonstrated that treatment with a reduced dose of nizatidine is effective as maintenance therapy following healing of active duodenal ulcers.**Mechanism of action *Nizatidine competes with histamine for binding at the H2-receptors on the gastric basolateral membrane of parietal cells. Competitive inhibition results in reduction of basal and nocturnal gastric acid secretions."
ULTRADOL 100mg 3 amp.TRAMADOLEVA PHARMAAnalgesics.Narcotic Opioid12(Indications):S This medication is an opioid analgesic, prescribed for moderate to severe pain in adults.It works by changing the way the body senses pain. SS(Contraindications):S acute alcoholism, head injuries, severe kidney impairment, breastfeeding, hypersensitivitySS(Dosage):SThe recommended dose is 50-100 mg (immediate release tablets) every 4-6 hours as needed for pain. The maximum dose is 400 mg/day.SIV/IM-Moderate to severe pain- The recommended dose is 50-100 mg 4-6 hourly.SS
ULTRADOL 100mg 6 supp.TRAMADOLEVA PHARMAAnalgesics.Narcotic Opioid12(Indications):* This medication is an opioid analgesic, prescribed for moderate to severe pain in adults.It works by changing the way the body senses pain. **(Contraindications):* acute alcoholism, head injuries, severe kidney impairment, breastfeeding, hypersensitivity**(Dosage):*The recommended dose is 50-100 mg (immediate release tablets) every 4-6 hours as needed for pain. The maximum dose is 400 mg/day.*IV/IM-Moderate to severe pain- The recommended dose is 50-100 mg 4-6 hourly.**
UROCOLINE 6 EFF. SACHETSCOLCHICINE -- HALFA BAR EXTRACT -- PIPERAZINE CITRATEEVA PHARMAAntigout.Analgesic5.25Mechanism of Action of Colchicine*It inhibits microtubule polymerization by binding to tubulin, one of the main constituents of microtubules. This tubulin is essential to mitosis, and therefore it inhibits the development of spindles as the nuclei are dividing. These results the death of rapidly proliferating cells. Colchicines in gout reduce lactic acid production by leukocytes, which results in a decrease in uric acid deposition, and it also reduce phagocytosis, with abatement of the inflammatory response.
VALYSERNEX 1000mg 20 f.c.capletVALACYCLOVIREVA PHARMAAnti-Viral.Nucleoside170"Indication For the treatment or suppression of cold sores (herpes labialis), herpes zoster (shingles), genital herpes in immunocompetent individuals, and recurrent genital herpes in HIV-infected individuals.*Mechanism of action Valaciclovir is phosphorylated by viral thymidine kinase to acyclovir triphosphate (the active metabolite) which then inhibits herpes viral DNA replication by competitive inhibition of viral DNA polymerase, and by incorporation into and termination of the growing viral DNA chain. When used as a substrate for viral DNA polymerase, acyclovir triphosphate competitively inhibits dATP leading to the formation of faulty DNA. This is where acyclovir triphosphate is incorporated into the DNA strand replacing many of the adenosine bases. This results in the prevention of DNA synthesis, as phosphodiester bridges can longer to be built, destabilizing the strand."
VALYSERNEX 500mg f.c. capletVALACYCLOVIREVA PHARMAAnti-Viral.Nucleoside50"Indication For the treatment or suppression of cold sores (herpes labialis), herpes zoster (shingles), genital herpes in immunocompetent individuals, and recurrent genital herpes in HIV-infected individuals.*Mechanism of action Valaciclovir is phosphorylated by viral thymidine kinase to acyclovir triphosphate (the active metabolite) which then inhibits herpes viral DNA replication by competitive inhibition of viral DNA polymerase, and by incorporation into and termination of the growing viral DNA chain. When used as a substrate for viral DNA polymerase, acyclovir triphosphate competitively inhibits dATP leading to the formation of faulty DNA. This is where acyclovir triphosphate is incorporated into the DNA strand replacing many of the adenosine bases. This results in the prevention of DNA synthesis, as phosphodiester bridges can longer to be built, destabilizing the strand."
VELGAROL 5mg/100gm top. Oint.CALCIPOTRIOLEVA PHARMA41"Description *Calcipotriol (INN) or calcipotriene (USAN) is a sythetic derivative of calcitriol or Vitamin D.**Indication *For the treatment of moderate plaque psoriasis in adults.**Mechanism of action *The precise mechanism of calcipotriol in remitting psoriasis is not well-understood. However, it has been shown to have comparable affinity with calcitriol for the Vitamin D receptor, while being less than 1% as active as the calcitriol in regulating calcium metabolism. The Vitamin D receptor (VDR) belongs to the steroid/thyroid receptor superfamily, and is found on the cells of many different tissues including the thyroid, bone, kindney, and T cells of the immune system. T cells are known to play a role in psoriasis, and it is thought that the binding of calcipotriol to the VDR modulates the T cells gene transcription of cell differentiation and proliferation related genes."
VENDEXINE 125ml syrupCHLORPHENIRAMINE -- DEXAMETHASONEEVA PHARMAAnti-histamine.Anti-Allergy.Combined With glucocorticoid steroid9.75"DEXAMETHASONE*Description *An anti-inflammatory 9-fluoro-glucocorticoid.*Mechanism of action Dexamethasone is a glucocorticoid agonist. Unbound dexamethasone crosses cell membranes and binds with high affinity to specific cytoplasmic glucocorticoid receptors. This complex binds to DNA elements (glucocorticoid response elements) which results in a modification of transcription and, hence, protein synthesis in order to achieve inhibition of leukocyte infiltration at the site of inflammation, interference in the function of mediators of inflammatory response, suppression of humoral immune responses, and reduction in edema or scar tissue. The antiinflammatory actions of dexamethasone are thought to involve phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes."
VIDANE SYRUP 120 MLTHYME LIQUID EXT. -- WHITE PINE EXT. -- ANISE OIL -- HONEYEVA PHARMA10
VIRECTA 100mg 9 F.C. Tab.SILDENAFILEVA PHARMASexual tonic41About Sildenafil Citrate*Phosphodiesterase-5 Enzyme Inhibitor, Anti-erectile dysfunction agent.SMechanism of Action of Sildenafil CitrateSSildenafil is a phosphodiesterase enzyme (PDE5) inhibitor. This enzyme is responsible for the degradation cyclic guanosine monophosphate (cGMP) produced in reaction to sexual stimulation. The more cGMP is available, the more durable the erection. Sildenafil inhibits the PDE5 enzyme, preserving cGMP levels, therefore aiding erection viability and durability SErection of the penis is caused by the filling of the penis with blood. Filling occurs because the blood vessels that bring blood to the penis increase in size and deliver more blood to the penis and at the same time, the blood vessels that take blood away from the penis decrease in size and remove less blood from the penis. SSexual stimulation that leads to an erection causes the production and release of nitric oxide in the corpora cavernosa of the penis.
VIRECTA 50mg 30 F.C. Tab.SILDENAFILEVA PHARMASexual tonic54About Sildenafil Citrate*Phosphodiesterase-5 Enzyme Inhibitor, Anti-erectile dysfunction agent.*Mechanism of Action of Sildenafil Citrate*Sildenafil is a phosphodiesterase enzyme (PDE5) inhibitor. This enzyme is responsible for the degradation cyclic guanosine monophosphate (cGMP) produced in reaction to sexual stimulation. The more cGMP is available, the more durable the erection. Sildenafil inhibits the PDE5 enzyme, preserving cGMP levels, therefore aiding erection viability and durability *Erection of the penis is caused by the filling of the penis with blood. Filling occurs because the blood vessels that bring blood to the penis increase in size and deliver more blood to the penis and at the same time, the blood vessels that take blood away from the penis decrease in size and remove less blood from the penis. *Sexual stimulation that leads to an erection causes the production and release of nitric oxide in the corpora cavernosa of the penis.
VITACAL 120ml syrupCALCIUM LEVULINATE -- VITAMIN D -- VITAMIN B12EVA PHARMA5
VITAFERROL 30 soft gelatin Caps.FOLIC ACID -- IRON -- MANGANESE -- VITAMIN B12 -- VITAMIN C -- ZINCEVA PHARMAMulti-Vitamins.Comination27PROPERTIES:*VitaferroI is a well balanced formula that allows maximal absorption and utilization of iron. It contains Ferrous fumarate which has the highest content of elemental iron compared to other iron salts. The product also contains Cyanocobalamin (B12) which helps building up of nucleic acids necessary for body cells and red cells formation. Ascorbic acid is included to facilitate the absorption of iron by maintaining more of the iron in the absorbable ferrous state, while Folic acid, Manganese and Zinc are considered necessary with iron as supplements for hemoglobin synthesis.*INDICATIONS:*Treatment and prophylaxis of iron deficiency anemia in cases of: blood loss of various origin (menstruation, hemorrhage, surgical operations), nutritional deficiency, adolescence and convalescence.Prophylaxis during pregnancy.
VITAFERROL elixir 120 MLIRON -- NICOTINAMIDE -- PANTHENOL -- VITAMIN B1 -- VITAMIN B2 -- VITAMIN B6 -- VITAMIN B12EVA PHARMAMulti-Vitamins.Comination9PROPERTIES:*Vitaferrol elixir contains vitamins, the building block of the body together with a novel iron preparation, which contains non-ionic ferric iron and polymaltose in a stable complex. This facilitates a controlled absorption of the ferric iron when it comes in contact with the mucosal cell surface. The polynuclear iron (III)-hydroxide cores are superficially surrounded by a number of non-covalently bound polymaltose molecules. The complex is stable and doesnï؟½t release ionic iron under physiological conditions. The iron in the polynuclear cores is bound in a similar structure as in the case of physiologically occurring ferritin. Due to this similarity, only the iron (III) of the complex is absorbed by an active absorption process. By means of competitive ligand exchange, any iron binding protein in the gastrointestinal fluid and on the surface of the epithelium can take up iron (III).
ZANOGLIDE 2/30 mg 30 tab.GLIMEPIRIDE -- PIOGLITAZONEEVA PHARMAAnti-Diabetic.Combined Secretagogues -- Sensitizers36"About Glimepiride*Third-generation sulfonylurea, Oral Antidiabetic Agent.*Mechanism of Action of Glimepiride*It is a potent antidiabetic drug which exerts its action by increasing insulin release from the pancreas and by improving glucose tolerance. It acts on the ""sulfonylurea receptors"" on pancreatic ?-cell membrane and reduces conductance of ATP sensitive K -- channels and thus causes depolarization. This enhances Ca2 -- influx and degranultion and thus increases insulin secretion rate at any glucose concentration. It primarily increases 2nd phase insulin secretion and has little effect on 1st phase. It also slows hepatic degradation of insulin and minor action of reducing glucagon release and increasing Somatostatin release. It also exerts stronger extrapancreatic action- by sensitizing the target tissues such as liver to insulin action. It increases the number of insulin receptors and through a post receptor action improving translation of receptor activation."
ZANOGLIDE 4/30 mg 30 tab.GLIMEPIRIDE -- PIOGLITAZONEEVA PHARMAAnti-Diabetic.Combined Secretagogues -- Sensitizers39"About Glimepiride*Third-generation sulfonylurea, Oral Antidiabetic Agent.*Mechanism of Action of Glimepiride*It is a potent antidiabetic drug which exerts its action by increasing insulin release from the pancreas and by improving glucose tolerance. It acts on the ""sulfonylurea receptors"" on pancreatic ?-cell membrane and reduces conductance of ATP sensitive K -- channels and thus causes depolarization. This enhances Ca2 -- influx and degranultion and thus increases insulin secretion rate at any glucose concentration. It primarily increases 2nd phase insulin secretion and has little effect on 1st phase. It also slows hepatic degradation of insulin and minor action of reducing glucagon release and increasing Somatostatin release. It also exerts stronger extrapancreatic action- by sensitizing the target tissues such as liver to insulin action. It increases the number of insulin receptors and through a post receptor action improving translation of receptor activation."
ZEFICAM 4mg 20 F.C.tab.LORNOXICAMEVA PHARMANSAID.Oxicam13About Lornoxicam*Non-steroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic (pain relieving), anti-inflammatory and antipyretic (fever reducing) properties. It is available in oral and parenteral formulations.**Mechanism of Action of Lornoxicam*Like other NSAIDs, lornoxicam inhibits prostaglandin biosynthesis by blocking the enzyme cyclooxygenase. Lornoxicam inhibits both isoforms in the same concentration range, that is, the ratio of COX-1 inhibition to COX-2 inhibition is 1:1. It readily penetrates into the synovial fluid.**Interactions for Lornoxicam*1.Vitamin K antagonists like warfarin increases the risk of bleeding. *2.Ciclosporin can lead to reduced kidney function, and to acute renal failure in rare cases. *3.Lornoxicam can also increase the adverse effects of lithium, methotrexate and digoxin and its derivatives. *4.The effect of diuretics, ACE inhibitors and angiotensin II receptor antagonists can be reduced, but this is only relevant in patient
ZEFICAM 8mg 20 F.C. TABS.LORNOXICAMEVA PHARMANSAID.Oxicam14About Lornoxicam*Non-steroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic (pain relieving), anti-inflammatory and antipyretic (fever reducing) properties. It is available in oral and parenteral formulations.**Mechanism of Action of Lornoxicam*Like other NSAIDs, lornoxicam inhibits prostaglandin biosynthesis by blocking the enzyme cyclooxygenase. Lornoxicam inhibits both isoforms in the same concentration range, that is, the ratio of COX-1 inhibition to COX-2 inhibition is 1:1. It readily penetrates into the synovial fluid.**Interactions for Lornoxicam*1.Vitamin K antagonists like warfarin increases the risk of bleeding. *2.Ciclosporin can lead to reduced kidney function, and to acute renal failure in rare cases. *3.Lornoxicam can also increase the adverse effects of lithium, methotrexate and digoxin and its derivatives. *4.The effect of diuretics, ACE inhibitors and angiotensin II receptor antagonists can be reduced, but this is only relevant in patient
ZEFICAM 8mg/2ml vial for I.M./I.V. inj.LORNOXICAMEVA PHARMANSAID.Oxicam6.5About Lornoxicam*Non-steroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic (pain relieving), anti-inflammatory and antipyretic (fever reducing) properties. It is available in oral and parenteral formulations.**Mechanism of Action of Lornoxicam*Like other NSAIDs, lornoxicam inhibits prostaglandin biosynthesis by blocking the enzyme cyclooxygenase. Lornoxicam inhibits both isoforms in the same concentration range, that is, the ratio of COX-1 inhibition to COX-2 inhibition is 1:1. It readily penetrates into the synovial fluid.**Interactions for Lornoxicam*1.Vitamin K antagonists like warfarin increases the risk of bleeding. *2.Ciclosporin can lead to reduced kidney function, and to acute renal failure in rare cases. *3.Lornoxicam can also increase the adverse effects of lithium, methotrexate and digoxin and its derivatives. *4.The effect of diuretics, ACE inhibitors and angiotensin II receptor antagonists can be reduced, but this is only relevant in patient
ZIDIN 300mg 10f.c.tab.ZIDOVUDINEEVA PHARMAAnti-Viral.Nucleoside60
ZOFATRONE 4mg/2ml 3 amp. For I.V/I.M inj.ONDANSETRONEVA PHARMA49.5About Ondansetron*Selective serotonin 5-HT3 receptor antagonist, Imidazole derivative, Antiemetic.*Mechanism of Action of Ondansetron*Ondansetron is a selective 5HT3 receptor antagonist. 5HT3 receptors are present in vagal nerve terminals and chemoreceptor trigger zone of area postrema of the brain. *Cytotoxic chemotherapy is associated with release of Serotonin from Enterochromaffin cells in the small intestine. Serotonin triggers vomiting through 5HT3 vagal receptor that activates the vomiting reflex. Since Ondansetron is a 5HT3 receptor antagonist, it is indicated for the prevention of nausea and vomiting associated in chemotherapy. *Anaesthetic adjuncts: It is used preoperatively in order to reduce the post operative vomiting.
ZOFATRONE 8mg/4ml 3 amp. For I.V/I.M inj.ONDANSETRONEVA PHARMA72About Ondansetron*Selective serotonin 5-HT3 receptor antagonist, Imidazole derivative, Antiemetic.*Mechanism of Action of Ondansetron*Ondansetron is a selective 5HT3 receptor antagonist. 5HT3 receptors are present in vagal nerve terminals and chemoreceptor trigger zone of area postrema of the brain. *Cytotoxic chemotherapy is associated with release of Serotonin from Enterochromaffin cells in the small intestine. Serotonin triggers vomiting through 5HT3 vagal receptor that activates the vomiting reflex. Since Ondansetron is a 5HT3 receptor antagonist, it is indicated for the prevention of nausea and vomiting associated in chemotherapy. *Anaesthetic adjuncts: It is used preoperatively in order to reduce the post operative vomiting.
ZOPICLONE 7.5mg 10 F.C.tabs.ZOPICLONEEVA PHARMApsychiatric.Anxiolytics-hypnotics9About Zopiclone*A non-benzodiazepine, a cyclopyrrolone derivative, Hypnotic,Sedative.*Mechanism of Action of Zopiclone*Zopiclone is a non benzodiazepine sedative hypnotic drug. It has agonistic action on omega1 binding site of alpha1 GABA-A receptor subunit. Zopiclone potentiates the action of GABA and decreases firing rate of neurons. This will produce a sedative-hypnotic effect.*Indications for Zopiclone*1. Insomnia*Interactions for Zopiclone*Metoclopramide: Concomitant administration may increase the plasma concentration of zopiclone. *Atropine: May decrease its plasma concentration, when given concurrently. *Trimipramine: If given along with Zopiclone may result in lessened antidepressant effect of the former.

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